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Articles 811 - 840 of 4171
Full-Text Articles in Public Health
Mold And Dampness In The Built Environment, Cheryl Marcham
Mold And Dampness In The Built Environment, Cheryl Marcham
Publications
This white paper calls on certified industrial hygienists and IH/OEHS professionals who practice in this area to be informed about the important of systematic building inspections and the strengths and weaknesses of sampling methods. It provides information on common misapprehensions in the lay community about such issues as mycotoxins.
A Unique Advantage Of A 24-Hour Surgical Delay In Autologous Breast Reconstruction, Devin M. Melancon, Daniel Yoo, Zachary Stern-Buchbinder, Samantha Morin, Hugo St. Hilaire, Robert J. Allen
A Unique Advantage Of A 24-Hour Surgical Delay In Autologous Breast Reconstruction, Devin M. Melancon, Daniel Yoo, Zachary Stern-Buchbinder, Samantha Morin, Hugo St. Hilaire, Robert J. Allen
School of Medicine Faculty Publications
Summary: The surgical delay technique can be used effectively in autologous breast reconstruction when there is unfavorable flap vascular anatomy or when the reconstruction necessitates a larger volume of donor tissue to obtain optimal results. The length of time between surgically delaying the flap to pedicle division and inset of the flap often varies based on surgeon preference but is typically approximately a week or longer. The authors present a case in which a 24-hour surgical delay was successfully used to augment deep inferior epigastric perforator flaps for autologous reconstruction. This technique is beneficial as it does not allow time …
Rare Variant Contribution To The Heritability Of Coronary Artery Disease, Ghislain Rocheleau, Shoa L Clarke, Gaëlle Auguste, Natalie R Hasbani, Alanna C Morrison, Adam S Heath, Lawrence F Bielak, Kruthika R Iyer, Erica P Young, Nathan O Stitziel, Goo Jun, Cecelia Laurie, Jai G Broome, Alyna T Khan, Donna K Arnett, Lewis C Becker, Joshua C Bis, Eric Boerwinkle, Donald W Bowden, April P Carson, Patrick T Ellinor, Myriam Fornage, Nora Franceschini, Barry I Freedman, Nancy L Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E Kenny, Charles Kooperberg, Brian G Kral, Ruth J F Loos, Sharon M Lutz, Joann E Manson, Lisa W Martin, Braxton D Mitchell, Rami Nassir, Nicholette D Palmer, Wendy S Post, Michael H Preuss, Bruce M Psaty, Laura M Raffield, Elizabeth A Regan, Stephen S Rich, Jennifer A Smith, Kent D Taylor, Lisa R Yanek, Kendra A Young, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Austin T Hilliard, Catherine Tcheandjieu, Patricia A Peyser, Ramachandran S Vasan, Jerome I Rotter, Clint L Miller, Themistocles L Assimes, Paul S De Vries, Ron Do
Rare Variant Contribution To The Heritability Of Coronary Artery Disease, Ghislain Rocheleau, Shoa L Clarke, Gaëlle Auguste, Natalie R Hasbani, Alanna C Morrison, Adam S Heath, Lawrence F Bielak, Kruthika R Iyer, Erica P Young, Nathan O Stitziel, Goo Jun, Cecelia Laurie, Jai G Broome, Alyna T Khan, Donna K Arnett, Lewis C Becker, Joshua C Bis, Eric Boerwinkle, Donald W Bowden, April P Carson, Patrick T Ellinor, Myriam Fornage, Nora Franceschini, Barry I Freedman, Nancy L Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E Kenny, Charles Kooperberg, Brian G Kral, Ruth J F Loos, Sharon M Lutz, Joann E Manson, Lisa W Martin, Braxton D Mitchell, Rami Nassir, Nicholette D Palmer, Wendy S Post, Michael H Preuss, Bruce M Psaty, Laura M Raffield, Elizabeth A Regan, Stephen S Rich, Jennifer A Smith, Kent D Taylor, Lisa R Yanek, Kendra A Young, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Austin T Hilliard, Catherine Tcheandjieu, Patricia A Peyser, Ramachandran S Vasan, Jerome I Rotter, Clint L Miller, Themistocles L Assimes, Paul S De Vries, Ron Do
Faculty, Staff and Student Publications
Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 controls of European ancestry from the NHLBI TOPMed program. We estimate CAD heritability at 34.3% assuming a prevalence of 8.2%. Ultra-rare (minor allele frequency ≤ 0.1%) variants with low linkage disequilibrium (LD) score contribute ~50% of the heritability. We also investigate CAD heritability enrichment using a diverse set of functional annotations: i) constraint; ii) predicted protein-altering impact; iii) cis-regulatory elements from a cell-specific chromatin …
Predisposing, Enabling, And Need Factors Influencing Health-Related Quality Of Life Among People With Metabolic Syndrome, Olajide Adekunle, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown
Predisposing, Enabling, And Need Factors Influencing Health-Related Quality Of Life Among People With Metabolic Syndrome, Olajide Adekunle, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown
Pharmacy Faculty Articles and Research
Background
Metabolic syndrome (MetS) continues to impact the health-related quality of life (HRQoL) of patients despite various available therapeutic interventions. There is a dearth of information on how patient-centered factors holistically predict HRQoL to provide more insights on addressing MetS.Objective
To predict the HRQoL of patients with MetS in the Southern states, using the predisposing, enabling, and need factors.Methods
The study adopted a cross-sectional approach in collecting 706 complete surveys on HRQoL assessment using the EQ-5D-5L survey and demographic characteristics based on the predisposing, enabling, and need factors of Andersen’s Behavioral model. The study focused on people with …Promoting Healthful And Diverse Eating Behaviours Through An Extracurricular Culinary Skills Intervention In Philadelphia, Matthew D. Kearney, Arlene R. Maheu, Madalyn Booth, Andrew B. Newberg, Peter F. Cronholm, Soussan Ayubcha
Promoting Healthful And Diverse Eating Behaviours Through An Extracurricular Culinary Skills Intervention In Philadelphia, Matthew D. Kearney, Arlene R. Maheu, Madalyn Booth, Andrew B. Newberg, Peter F. Cronholm, Soussan Ayubcha
SKMC Student Presentations and Publications
In the current study we evaluated an afterschool nutrition education programme, called Vetri Cooking Lab (VCL), for promoting healthy and diverse eating habits among at-risk children in the Greater Philadelphia area. To understand potential programme impacts, we conducted a longitudinal analysis of survey data collected before and after participation in VCL. Main study included cooking confidence, cooking knowledge, changes in dietary consumption behaviours, and changes in vegetable preferences. Participants included students in grades 3-11 enrolled in VCL during the 2018-19 school year at VCL sites (n = 60) throughout Philadelphia, PA, and Camden, NJ. Eligible participants completed surveys both before …
Transition Aged Youth Substance Use At Electric Dance Music Events In The Tampa Bay Area: A Qualitative Study Of Awareness And Prevention, Danielle Vinciguerra
Transition Aged Youth Substance Use At Electric Dance Music Events In The Tampa Bay Area: A Qualitative Study Of Awareness And Prevention, Danielle Vinciguerra
USF Tampa Graduate Theses and Dissertations
The study investigates substance use among Transitional Aged Youth (TAY), particularly focusing on Electronic Dance Music (EDM) events in the Tampa Bay area. TAY, defined as individuals aged 18-29, experience significant psychological, biological, and developmental changes, which can lead to increased vulnerability to substance use. The study examines the prevalence and patterns of substance use, specifically ketamine and cocaine, among TAY at EDM events. Exploratory qualitative data collection method was utilized for the study. Applying Social Learning Theory as a framework, the research explores the beliefs, attitudes, experiences, and community influences that contribute to substance use within this demographic. Data …
Understanding Long Covid: Navigating The Journey To Recovery, Heather H. Kelley, Rachel Byers, Ty Aller, Timothy Keady
Understanding Long Covid: Navigating The Journey To Recovery, Heather H. Kelley, Rachel Byers, Ty Aller, Timothy Keady
All Current Publications
This fact sheet provides very basic facts on what long COVID is and information on how to navigate the healthcare system and cope with long COVID.
Gender And Sexuality Awareness In Medical Education And Practice: Mixed Methods Study, Rola Khamisy-Farah, Eden Biras, Rabie Shehadeh, Ruba Tuma, Hisham Atwan, Anna Siri, Manlio Converti, Francesco Chirico, Łukasz Szarpak, Carlo Biz, Raymond Farah, Nicola Bragazzi
Gender And Sexuality Awareness In Medical Education And Practice: Mixed Methods Study, Rola Khamisy-Farah, Eden Biras, Rabie Shehadeh, Ruba Tuma, Hisham Atwan, Anna Siri, Manlio Converti, Francesco Chirico, Łukasz Szarpak, Carlo Biz, Raymond Farah, Nicola Bragazzi
Faculty, Staff and Students Publications
BACKGROUND: The integration of gender and sexuality awareness in health care is increasingly recognized as vital for patient outcomes. Despite this, there is a notable lack of comprehensive data on the current state of physicians' training and perceptions in these areas, leading to a gap in targeted educational interventions and optimal health care delivery.
OBJECTIVE: The study's aim was to explore the experiences and perceptions of attending and resident physicians regarding the inclusion of gender and sexuality content in medical school curricula and professional practice in Israel.
METHODS: This cross-sectional survey targeted a diverse group of physicians across various specializations …
Dna Methylation Near Mad1l1, Kdm2b, And Socs3 Mediates The Effect Of Socioeconomic Status On Elevated Body Mass Index In African American Adults, Láshauntá Glover, Adam G Lilly, Anne E Justice, Annie Green Howard, Brooke S Staley, Yujie Wang, Helen M Kamens, Kendra Ferrier, Jan Bressler, Laura Loehr, Laura M Raffield, Mario Sims, Kari E North, Lindsay Fernández-Rhodes
Dna Methylation Near Mad1l1, Kdm2b, And Socs3 Mediates The Effect Of Socioeconomic Status On Elevated Body Mass Index In African American Adults, Láshauntá Glover, Adam G Lilly, Anne E Justice, Annie Green Howard, Brooke S Staley, Yujie Wang, Helen M Kamens, Kendra Ferrier, Jan Bressler, Laura Loehr, Laura M Raffield, Mario Sims, Kari E North, Lindsay Fernández-Rhodes
Faculty, Staff and Student Publications
Obesity and poverty disproportionally affect African American persons. Epigenetic mechanisms could partially explain the association between socioeconomic disadvantage and body mass index (BMI). We examined the extent to which epigenetic mechanisms mediate the effect of socioeconomic status (SES) on BMI. Using data from African American adults from the Atherosclerosis Risk in Communities (ARIC) Study (n = 2664, mean age = 57 years), education, income, and occupation were used to create a composite SES score at visit 1 (1987-1989). We conducted two methylation-wide association analyses to identify associations between SES (visit 1), BMI and cytosine-phosphate-guanine (CpG) sites measured at a subsequent …
Association Between Particulate Matter And Copd Among Adults In Alaska, Adeyemi Samuel Alimi
Association Between Particulate Matter And Copd Among Adults In Alaska, Adeyemi Samuel Alimi
Walden Dissertations and Doctoral Studies
Exposure to high levels of fine particulate matter (PM2.5) is emerging as a crucial risk factor for chronic obstructive pulmonary disease (COPD), a deadly lung disease with a significant public health burden. The Fairbanks North Star Borough (FNSB) in Alaska has one of the worst PM2.5 issues in the United States. The PM2.5 issues in the area are associated with increased wood-burning and temperature inversions in the winter and wildfires in the summer. Given these prevailing PM2.5 issues, this quantitative study was conducted using Alaska BRFSS datasets and a chi-square test to compare the COPD prevalence in the FNSB with …
Physician Perspectives About The Diagnosis And Management Of Acute Chest Syndrome, Neha Bhasin, Dana Marie Leblanc, Sean Yates, Quentin Eichbaum, An Pham, Deva Sharma, Li Zhang, Elliott P. Vichinsky, Ravi Sarode
Physician Perspectives About The Diagnosis And Management Of Acute Chest Syndrome, Neha Bhasin, Dana Marie Leblanc, Sean Yates, Quentin Eichbaum, An Pham, Deva Sharma, Li Zhang, Elliott P. Vichinsky, Ravi Sarode
School of Medicine Faculty Publications
Background: Acute chest syndrome (ACS) is the leading cause of mortality, accounting for 25% of all deaths among individuals with sickle cell disease (SCD). There is a lack of evidence-based laboratory and clinical risk stratification guidelines for the diagnosis and management of ACS. Study Design and Methods: To better understand physician practices for the management of ACS in the United States, we created an ACS Working Group including hematology and transfusion medicine physicians from four different SCD treatment centers in the United States. The working group created a physician survey that included physician demographics and ACS diagnostic criteria that they …
Maternal Cortisol Concentration Is Associated With Reduced Brain Activation To Infant Cry And More Intrusive Parenting Behavior, Andrew Erhart, Sarah Enos Watamura, Aviva K. Olsavsky, Alexander J. Dufford, Rebekah C. Tribble, Tom Yeh, Pilyoung Kim
Maternal Cortisol Concentration Is Associated With Reduced Brain Activation To Infant Cry And More Intrusive Parenting Behavior, Andrew Erhart, Sarah Enos Watamura, Aviva K. Olsavsky, Alexander J. Dufford, Rebekah C. Tribble, Tom Yeh, Pilyoung Kim
Psychology: Faculty Scholarship
Previous research indicates that maternal cortisol function and maternal brain response to infant are each in turn related to variations in parenting behavior. However, little is known about how maternal cortisol and maternal brain function are associated, thus studying these two mechanisms together may improve our understanding of how maternal cortisol assessed during interactions with own infant is associated with brain response to infant cry. First-time mothers (N = 59) of infants aged 3-4 months old were recruited to participate. Mothers' cortisol concentration was measured during a naturalistic interaction with their infant and their behavior was coded for two parenting …
Sars-Cov-2 Vaccine Improved Hemostasis Of A Patient With Protein S Deficiency: A Case Report, Mohammad A. Mohammad, Alaa Malik, Lekha Thangada, Diana Polanía-Villanueva, Jovanny Zabaleta, Rinku Majumder
Sars-Cov-2 Vaccine Improved Hemostasis Of A Patient With Protein S Deficiency: A Case Report, Mohammad A. Mohammad, Alaa Malik, Lekha Thangada, Diana Polanía-Villanueva, Jovanny Zabaleta, Rinku Majumder
School of Medicine Faculty Publications
A 16-year-old patient, while an infant, incurred right-sided hemiparesis and had difficulty breast feeding. She was later diagnosed with a neonatal stroke and her genetic testing showed a missense mutation in her PROS1 (Protein S) gene. Both her grandfather and father, but not her mother, had hereditary Protein S (PS) deficiency. The patient was not prescribed any mediation due to her young age but was frequently checked by her physician. The patient’s plasma was first collected at the age of 13, and the isolated plasma from the patient and her father were analyzed by aPTT, thrombin generation, and enzyme-linked immunosorbent …
Sources Of Information That Introduced Undergraduate Students To Their Allied Health Major, Erin Vanderbunt
Sources Of Information That Introduced Undergraduate Students To Their Allied Health Major, Erin Vanderbunt
Internet Journal of Allied Health Sciences and Practice
Purpose: Selecting a college major can be overwhelming for undergraduate students. The factors influencing major selection not only impact student success and degree completion time but also affect university recruitment and retention strategies. Therefore, the purpose of this study was to identify the most influential sources of information that first introduced undergraduate students to their current major of nutrition, public health, or speech pathology and sought to determine if any differences existed between the academic majors or by the demographic variables of gender or racial/ethnic backgrounds. Methods: A total of 121 undergraduate students from a regional, midwest institution participated in …
Primary Prevention And Motivational Interviewing: Patterns In Athletic Training, Mark C. West, Justin P. Young, Matthew J. Rivera, Kenneth E. Games
Primary Prevention And Motivational Interviewing: Patterns In Athletic Training, Mark C. West, Justin P. Young, Matthew J. Rivera, Kenneth E. Games
Internet Journal of Allied Health Sciences and Practice
Background: The BOC practice analysis defines the first domain as Risk Reduction, Wellness and Health Literacy including, “Promoting healthy lifestyle behaviors with effective education and communication.” There is limited evidence on primary prevention measures athletic trainers (ATs) use to address health-related behaviors. Motivational interviewing is an evidence-based patient-centered style of communication used to help patients modify detrimental health behaviors to improve health outcomes. The purpose of this study was to explore knowledge and practice patterns of primary prevention and motivational interviewing in athletic training. Methods: We used a cross-sectional, web-based survey (Qualtrics, Provo, UT). The survey contained demographic questions, …
How Have Occupational Therapy Services Been Delivered During The Covid-19 Pandemic?, Hulya Yucel, Selen Aydoner
How Have Occupational Therapy Services Been Delivered During The Covid-19 Pandemic?, Hulya Yucel, Selen Aydoner
Internet Journal of Allied Health Sciences and Practice
The provision of traditional healthcare services has encountered obstacles due to the Coronavirus Disease-2019 (COVID-19) pandemic. The inability of healthcare professionals and clients to survive the pandemic and the inadequacy of personal protective equipment have created uncertainties regarding the appropriate practices for addressing individuals' health conditions. Furthermore, the field of rehabilitation, including occupational therapy, has experienced changes in the delivery of traditional practices. Therefore, this review aimed to examine occupational therapy services delivered during the COVID-19 pandemic. As a result of the literature review, the most commonly provided services by occupational therapists during COVID-19 were discussed and a total of …
Agricultural Producers' Perceptions Of Stressors: A Study On Controllability And Persistency, Mary Nelson Robertson, Devon Mills, Brice A. Fortinberry, Mary Marshall Waller, Hunter H. Thompson, Marina Denny, David Buys
Agricultural Producers' Perceptions Of Stressors: A Study On Controllability And Persistency, Mary Nelson Robertson, Devon Mills, Brice A. Fortinberry, Mary Marshall Waller, Hunter H. Thompson, Marina Denny, David Buys
Journal of Public Health in the Deep South
Farm stress negatively impacts agricultural producers’ (APs) physical and mental health. The average age of agricultural producers has increased in every USDA agricultural census since 1945, and the stressors may be either or both caused or exacerbated by increasing age. The Cooperative Extension Service is well-known for working with APs and is well-equipped to address these concerns for this aging population. To better understand farm-related stressors, this study examines APs’ and Extension agents’ perceptions of major stressors faced by APs. Focus groups were held to identify stressors and determine the controllability and persistency of those stressors. The mean age of …
Guía Para Planes Escolares De Gestión Del Riesgo De Desastres, Diego Alejandro Mesa Baquero, Dalia Xiomara Suárez Pulido, Luis Miguel Castañeda Galindo, María Paula Gómez Leal, Diana Julieth Garzón Sánchez, Natalia Gómez Díaz
Guía Para Planes Escolares De Gestión Del Riesgo De Desastres, Diego Alejandro Mesa Baquero, Dalia Xiomara Suárez Pulido, Luis Miguel Castañeda Galindo, María Paula Gómez Leal, Diana Julieth Garzón Sánchez, Natalia Gómez Díaz
Ciencias Agropecuarias
A través de alianzas y encuentros interinstitucionales con todas las entidades territoriales relacionadas en educación ambiental y vinculando a todos los actores de la comunidad educativa tanto docentes directivos, docentes y estudiantes como organizaciones comunitarias y líderes locales para enriquecer la implementación del Proyecto Ambiental Escolar (PRAE) y los Planes Escolares de Gestión de Riesgo de Desastres (PEGR) de los respectivos establecimientos educativos. Esta guía metodológica establecerá los lineamientos para la formulación de los PEGR que contribuirán a la gestión de sus riesgos en cada una de las instituciones educativas y de sus sedes mediante la implementación de los procesos …
Reactions To The Mpox Vaccine Regarding Absences And Disruption Of Daily Activities In The United States, Robert Rossi
Reactions To The Mpox Vaccine Regarding Absences And Disruption Of Daily Activities In The United States, Robert Rossi
Walden Dissertations and Doctoral Studies
Since its global outbreak in 2022, the monkeypox (Mpox) virus has infected over 32,000 individuals in the United States, resulting in approximately 58 deaths. Although the JYNNEOS vaccine is effective at disease prevention, it has also been found to cause side effects, such as a disruption in daily activities and/or attendance at work or school. This quantitative, cross-sectional study was conducted to investigate whether differences existed in reactions to the Mpox vaccine, using secondary data from the Centers for Disease Control and Prevention’s V-safe Mpox survey. The two dependent variables were work/school absenteeism and disruption of daily activities, and the …
Stigma Experience Of Men With Eating Disorders: A Scoping Review, Rachael Maloney, Louise Lunney, Olivia-Mari Lennox, Elena Vaughan, Colette Kelly
Stigma Experience Of Men With Eating Disorders: A Scoping Review, Rachael Maloney, Louise Lunney, Olivia-Mari Lennox, Elena Vaughan, Colette Kelly
Journal of Social Care
This scoping review aimed to synthesise the literature concerning the stigma experiences of men with eating disorders. Seven databases were searched using relevant keywords and subject headings. Following deduplication, articles published since 2000 were screened against eligibility criteria. Key information was charted and analysed using descriptive statistics and deductive content analysis. The final sample (n=9) was synthesised under four categories of stigma experiences within the Health Stigma and Discrimination Framework. Internalised stigma was the most prevalent stigma experience across the included studies. This review suggests that men with eating disorders experience stigma in many forms and across various contexts, including …
Health Matters! Coloring And Activity Booklet (16-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
Health Matters! Coloring And Activity Booklet (16-Pages), Your Very Favorite, Children's Health, Lorraine Sheldon, May Bressler
English
Health Matters! is a English-language health literacy resource designed for pediatric patients and their families. Written at an approximately 6th-grade reading level, it supports patient education through engaging coloring and activity pages.
This booklet version includes a smaller selection of materials from the larger Health Matters! book. Developed for use in both hospital settings and the broader community, the resource promotes learning through interactive, age-appropriate activities.
This printable PDF version contains the complete collection of activities and comprises 16 pages. The resource was commissioned by Children's Health and prepared by Your Very Favorite.
Two Lives, Shruti Trehan Mbbs
Two Lives, Shruti Trehan Mbbs
Journal of Wellness
A busy oncologist makes a decision to leave her busy, thriving, community practice in the Mid-West and moves to a Veterans Affairs hospital in South Florida in the quest for a better work-life balance.
Whole-Genome Sequencing In 333,100 Individuals Reveals Rare Non-Coding Single Variant And Aggregate Associations With Height, Gareth Hawkes, Robin N Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Christine M Albert, Donna K Arnett, Allison E Ashley-Koch, Aneel A Ashrani, Kathleen C Barnes, Eric Boerwinkle, Jennifer A Brody, April P Carson, Nathalie Chami, Yii-Der Ida Chen, Mina K Chung, Joanne E Curran, Dawood Darbar, Patrick T Ellinor, Myrian Fornage, Victor R Gordeuk, Xiuqing Guo, Jiang He, Chii-Min Hwu, Rita R Kalyani, Robert Kaplan, Sharon L R Kardia, Charles Kooperberg, Ruth J F Loos, Steven A Lubitz, Ryan L Minster, Take Naseri, Satupa'itea Viali, Braxton D Mitchell, Joanne M Murabito, Nicholette D Palmer, Bruce M Psaty, Susan Redline, M Benjamin Shoemaker, Edwin K Silverman, Marilyn J Telen, Scott T Weiss, Lisa R Yanek, Hufeng Zhou, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Ching-Ti Liu, Kari E North, Anne E Justice, Jonathan M Locke, Nick Owens, Anna Murray, Kashyap Patel, Timothy M Frayling, Caroline F Wright, Andrew R Wood, Xihong Lin, Alisa Manning, Michael N Weedon
Whole-Genome Sequencing In 333,100 Individuals Reveals Rare Non-Coding Single Variant And Aggregate Associations With Height, Gareth Hawkes, Robin N Beaumont, Zilin Li, Ravi Mandla, Xihao Li, Christine M Albert, Donna K Arnett, Allison E Ashley-Koch, Aneel A Ashrani, Kathleen C Barnes, Eric Boerwinkle, Jennifer A Brody, April P Carson, Nathalie Chami, Yii-Der Ida Chen, Mina K Chung, Joanne E Curran, Dawood Darbar, Patrick T Ellinor, Myrian Fornage, Victor R Gordeuk, Xiuqing Guo, Jiang He, Chii-Min Hwu, Rita R Kalyani, Robert Kaplan, Sharon L R Kardia, Charles Kooperberg, Ruth J F Loos, Steven A Lubitz, Ryan L Minster, Take Naseri, Satupa'itea Viali, Braxton D Mitchell, Joanne M Murabito, Nicholette D Palmer, Bruce M Psaty, Susan Redline, M Benjamin Shoemaker, Edwin K Silverman, Marilyn J Telen, Scott T Weiss, Lisa R Yanek, Hufeng Zhou, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Ching-Ti Liu, Kari E North, Anne E Justice, Jonathan M Locke, Nick Owens, Anna Murray, Kashyap Patel, Timothy M Frayling, Caroline F Wright, Andrew R Wood, Xihong Lin, Alisa Manning, Michael N Weedon
Faculty, Staff and Student Publications
The role of rare non-coding variation in complex human phenotypes is still largely unknown. To elucidate the impact of rare variants in regulatory elements, we performed a whole-genome sequencing association analysis for height using 333,100 individuals from three datasets: UK Biobank (N = 200,003), TOPMed (N = 87,652) and All of Us (N = 45,445). We performed rare ( < 0.1% minor-allele-frequency) single-variant and aggregate testing of non-coding variants in regulatory regions based on proximal-regulatory, intergenic-regulatory and deep-intronic annotation. We observed 29 independent variants associated with height at P < 6×10-10" role="presentation" style="box-sizing: inherit; display: inline-block; line-height: 0; font-size: 18.08px; font-size-adjust: none; overflow-wrap: normal; text-wrap-mode: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; margin: 0px; padding: 1px 0px; color: rgb(33, 33, 33); font-family: BlinkMacSystemFont, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; position: relative;">6×10−106×10-10 after conditioning on previously reported variants, with effect sizes ranging from -7cm to +4.7 cm. We also identified and replicated non-coding aggregate-based associations proximal to HMGA1 containing variants associated with a 5 cm taller height and of highly-conserved variants in …
Semi-Supervised Machine Learning Method For Predicting Homogeneous Ancestry Groups To Assess Hardy-Weinberg Equilibrium In Diverse Whole-Genome Sequencing Studies, Derek Shyr, Rounak Dey, Xihao Li, Hufeng Zhou, Eric Boerwinkle, Steve Buyske, Mark Daly, Richard A Gibbs, Ira Hall, Tara Matise, Catherine Reeves, Nathan O Stitziel, Michael Zody, Benjamin M Neale, Xihong Lin
Semi-Supervised Machine Learning Method For Predicting Homogeneous Ancestry Groups To Assess Hardy-Weinberg Equilibrium In Diverse Whole-Genome Sequencing Studies, Derek Shyr, Rounak Dey, Xihao Li, Hufeng Zhou, Eric Boerwinkle, Steve Buyske, Mark Daly, Richard A Gibbs, Ira Hall, Tara Matise, Catherine Reeves, Nathan O Stitziel, Michael Zody, Benjamin M Neale, Xihong Lin
Faculty, Staff and Student Publications
Large-scale, multi-ethnic whole-genome sequencing (WGS) studies, such as the National Human Genome Research Institute Genome Sequencing Program's Centers for Common Disease Genomics (CCDG), play an important role in increasing diversity for genetic research. Before performing association analyses, assessing Hardy-Weinberg equilibrium (HWE) is a crucial step in quality control procedures to remove low quality variants and ensure valid downstream analyses. Diverse WGS studies contain ancestrally heterogeneous samples; however, commonly used HWE methods assume that the samples are homogeneous. Therefore, directly applying these to the whole dataset can yield statistically invalid results. To account for this heterogeneity, HWE can be tested on …
In Acute Severe Ulcerative Colitis Patients Who Receive Rescue Therapy, Prior Maintenance Therapy And Day 3 C-Reactive Protein After Rescue Therapy Are Associated With 12-Month Colectomy Risk, Jared A Sninsky, Ana-Maria Staicu, Edward L Barnes
In Acute Severe Ulcerative Colitis Patients Who Receive Rescue Therapy, Prior Maintenance Therapy And Day 3 C-Reactive Protein After Rescue Therapy Are Associated With 12-Month Colectomy Risk, Jared A Sninsky, Ana-Maria Staicu, Edward L Barnes
Faculty, Staff and Students Publications
No abstract provided.
Quality Improvement Of Breast And Cervical Cancer Screening Satisfaction Rate At A Utrgv Resident-Led Clinic., Eunbee Cho, Diana Othon Martinez, Jian Garcia Cruz, Nestor Gerardo Astorga, Martha Solis, Oliverio Abarca Guzman, Elimar Gonzalez Morales, Fatimah Bello
Quality Improvement Of Breast And Cervical Cancer Screening Satisfaction Rate At A Utrgv Resident-Led Clinic., Eunbee Cho, Diana Othon Martinez, Jian Garcia Cruz, Nestor Gerardo Astorga, Martha Solis, Oliverio Abarca Guzman, Elimar Gonzalez Morales, Fatimah Bello
Research Colloquium
Background: In the US, 77.3% of women aged 21-65 years have had a Pap smear within the past three years and around 75.9% of women aged 50-74 years reported having a mammogram within the past two years as recommended according to the U.S. Preventive Services Task Force (USPSTF). In UTRGV Resident-led Clinic located in Hidalgo County, the quality metrics data demonstrated screening satisfactory rate for cervical and breast cancer to be 18% in August 2023. This Quality Improvement project is aimed at enhancing the screening satisfactory rate of breast and cervical cancer by 20% at UTRGV Knapp IM Clinic by …
Prevalence And Factors Associated With Work-Related Musculoskeletal Disorder Among Central Sterile Supply Technicians In Nakhon Si Thammarat Province, Thailand, Withaya Chanchai Dr, Ratree Nacglud Ms, Keatkongkrai Bunnum Mr., Nureeya Promsorn Mrs., Laddawan Duangmusik Mrs., Warunee Suwanrat Mrs., Wichuda Chantasin, Kritsana Thonnan Ms.
Prevalence And Factors Associated With Work-Related Musculoskeletal Disorder Among Central Sterile Supply Technicians In Nakhon Si Thammarat Province, Thailand, Withaya Chanchai Dr, Ratree Nacglud Ms, Keatkongkrai Bunnum Mr., Nureeya Promsorn Mrs., Laddawan Duangmusik Mrs., Warunee Suwanrat Mrs., Wichuda Chantasin, Kritsana Thonnan Ms.
Chulalongkorn Medical Journal
Background: Central Sterile Supply Technicians (CSSTs) face an elevated risk of work-related musculoskeletal disorders (WMSDs), notably affecting the back.
Objective: This study aimed to examine the prevalence and factors associated with work-related musculoskeletal disorders among CSSTs in Nakhon Si Thammarat Province, Thailand.
Methods: A cross-sectional study in Nakhon Si Thammarat, Thailand, assessed WMSDs among CSSTs using self-administered questionnaires on demographics and symptoms. Out of 188 distributed, 179 were completed, evaluating disorder presence and severity during sterilization in 33 hospitals.
Results: The prevalence rate of work-related musculoskeletal disorders (WMSDs) in various body regions, particularly the upper back, at the …
Effect Of Aquatic Exercises On Patellofemoral Joint Dysfunction In Middle Age Obese Women, Akshaya Joshi, Sandeep Shinde, Sawani Aphale
Effect Of Aquatic Exercises On Patellofemoral Joint Dysfunction In Middle Age Obese Women, Akshaya Joshi, Sandeep Shinde, Sawani Aphale
Chulalongkorn Medical Journal
Background: The patellofemoral joint, known for its incongruence, is susceptible to dysfunction due to abnormal pathomechanics, especially with increased body mass causing excessive stress on knee cartilage, leading to degeneration and dysfunction. Dysfunction results in pain, limited range of motion, and diminished quality of life.
Objectives: To determine the effect of aquatic exercises on patellofemoral joint dysfunction in middle-aged obese women and to compare the effect of aquatic exercises with land-based exercises on patellofemoral joint dysfunction in middle-aged obese women.
Methods: In this experimental study, 100 subjects with patellofemoral joint dysfunction were separated into group …
Beyond Assistance: Amplifying The Lived Experiences Of Marginalized Communities Navigating Support Service Systems In Mississippi, Karla Mccullough, Rodney Washington, Angela A. Omondi
Beyond Assistance: Amplifying The Lived Experiences Of Marginalized Communities Navigating Support Service Systems In Mississippi, Karla Mccullough, Rodney Washington, Angela A. Omondi
Journal of Public Health in the Deep South
Background
Perceived dehumanizing experiences when interacting with social assistance caseworkers and providers can contribute to negative perceptions of the service system that may impede enrollment and retention of families in need thereby contributing to health disparities.
Purpose
This study aimed to use secondary analysis of qualitative data to explore the interaction between social services workers/providers and recipients from the perspectives of families seeking social support services in Mississippi.
Methods
This study analyzed secondary qualitative data from a sample of (n=15) representatives in Mississippi. Data was analyzed using a thematic analysis approach.
Results
Participants reported perceived dehumanized experiences such …
A Model For Developing Emergency Medical Services Instructor Knowledge, David Hall, Lisa Fee
A Model For Developing Emergency Medical Services Instructor Knowledge, David Hall, Lisa Fee
Journal of Public Health in the Deep South
PROBLEM: The task of educating Emergency Medical Services (EMS) providers requires EMS instructors to possess and convey translational knowledge and skills relevant to out-of-hospital emergency care. Insufficiently prepared or new EMS instructors may lack translational knowledge and skills along these lines and be at a deficit when it comes to educating EMS providers. PURPOSE: The project involved creation, implementation, and analysis of a model state EMS instructor core training program in Mississippi, with the aim of developing translational knowledge and skills for use by EMS instructors. METHOD: The project utilized a revised Evidence-Based Practice (EBP) model and a standardized survey …