Public Health Commons^™

Pharmacists' Role In Emergency Preparedness And Response, Jamie Kellner, Ginny Daniels, Maureen Moynihan, Joseph Stecyk, Kasie Bellmann, Natalie Dipietro

Pharmacy and Wellness Review

Over the past decade, an increased recognition of the need for budgeting and planning in case of terrorist attacks, use of infectious agents as weapons or major weather disasters has brought emergency preparedness to the forefront within health care systems and federal organizations. Pharmacists have taken active roles in activities related to emergency preparedness and response. New training initiatives and a comprehensive understanding of the overall needs in emergency situations enables pharmacists to utilize their drug knowledge and accessibility to the public to provide vital medical care in stressful situations.

Whooping Cough: A Pharmacist's Role In An Emerging Endemic, Haley Armstrong, Lydia Suchecki, Sarah Lipperman, Taylor Roberson, Andrew M. Roecker

Pharmacy and Wellness Review

Pertussis is an acute infectious disease caused by the organism Bordetella pertussis and characterized by a "whooping cough." Incidence of the disease had declined since the development of a vaccine, but is now increasing in reported cases. This increase has been attributed to both an increased awareness but also surmised to be related to a decrease in vaccinations. The pertussis vaccine is given in conjunction with tetanus and diphtheria vaccines to children before the age of 6 in five separate injections over the course of four to six years. A booster is now recommended for the older child and adults …

Emergency Contraception: A Comparison Of Levonorgestrel And Ulipristal Acetate, Tara Tokar, Rachel Muhlenkamp, Kelsey Lindsley, Alison Steinbrunner, Michelle Musser

Pharmacy and Wellness Review

Emergency contraceptives (EC) are a birth control method that is available to minimize unintended pregnancies that might result from unprotected intercourse. Several products are on the market and largely contain levonorgestrel as the active component, including Plan B One-Step®, Next Choice®, Next Choice One Dose™ and My Way®. These are labeled as effective up to 72 hours after intercourse and are available without a prescription. Another product, Ella™, contains ulipristal acetate and can be effective up to 120 hours after intercourse, but does require a prescription. Legislative issues have surrounded these products. At this point in time only Plan B …

Makena®: A Drug For Reducing The Risk Of Preterm Labor, Amanda Lovell, Kasie Bellman, Kelsey Fink, Jessica Beck, Michelle Musser

Pharmacy and Wellness Review

Makena®, hydroxyprogesterone caproate, is an intramuscular injection that is U.S. Food and Drug Administration (FDA) approved to reduce the risk of preterm delivery before 37 weeks of pregnancy in pregnant women with a history of spontaneous preterm birth, who are not currently carrying multiple children. One in nine babies born in the United States each year is born prematurely, or before 37 weeks gestation, and mothers who have previously delivered a premature baby are 2.5 times more likely to deliver another baby prematurely. Makena® is administered by a health care professional as a single intramuscular injection to the hip and …

Endometriosis: The Etiology And Recommended Treatment, Amanda Lovell, Kasie Bellmann, Kelsey Fink, Jessica Beck, Michelle Musser

Pharmacy and Wellness Review

Endometriosis is a gynecological condition that occurs in women between the ages of 15 and 49 years, in which endometrial cells grow outside the uterus. Normally, endometrial cells form the endometrium and respond to hormones throughout the menstrual cycle, but when endometrial cells are located outside the endometrium, painful bleeding and other side effects may occur. Treatment of endometriosis is usually symptomatic relief, including the use of oral contraceptives and other hormone replacement options, as well as non-steroidal anti-inflammatory drugs. To ensure that patients receive the appropriate treatment for this condition, pharmacists should be able to recognize the signs and …

Immunization Guidelines For Pregnant Women, Kelly Dye, Maria Laikos, Tristan Maiers, Eric Stack, Natalie Dipietro

Pharmacy and Wellness Review

There are many misconceptions among the general public regarding the administration of vaccinations during pregnancy. It is imperative for pharmacists to be current regarding guidelines and updates about recommended vaccines. Data from the Centers for Disease Control and Prevention (CDC) indicate that while some vaccines are highly recommended during pregnancy, others have limited safety data or are contraindicated. As new data emerges on the safety and efficacy of immunizations during pregnancy, pharmacists should continue to review the literature to stay up-to-date on vaccination recommendations. The CDC also has information available for pharmacists and other health care professionals regarding the use …

Improving Maternal And Fetal Health: A Look At Thyroid Function During Pregnancy, Sarah Ginty, Jessica Beck, Taylor Gauthier, Amanda Meyer, Michelle R. Musser

Pharmacy and Wellness Review

Maintenance of thyroid function during pregnancy is critical for both maternal and fetal health and development; therefore, knowledge regarding the relationship between thyroid hormones and pregnancy is essential. The American Thyroid Association task force has developed clinical guidelines on the diagnosis and treatment of thyroid disease during pregnancy. Gestational thyroid diseases are divided into two classifications, hypothyroidism and hyperthyroidism, which are further divided into more specific classifications based on clinical presentation. Differentiation, diagnosis, and monitoring of thyroid diseases throughout pregnancy require assessing symptoms, as well as obtaining levels of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) concentration by a simple …

Lysteda® For Heavy Menstrual Bleeding, Erica B. Schoenberger, Todd A. Tucker Jr., Justin W. Steele, Amanda Meyer, Sandra L. Hrometz

Pharmacy and Wellness Review

Lysteda®, a novel formulation of tranexamic acid, is an antifibrinolytic medication recently approved by the Food and Drug Administration (FDA) for the treatment of heavy menstrual bleeding. Tranexamic acid has been shown to significantly reduce menstrual blood loss while simultaneously allowing a woman to safely become pregnant. The major advantage of Lysteda® (an oral modified-release formulation of tranexamic acid) compared to oral immediate-release tranexamic acid, is the decreased occurrence of gastrointestinal side effects. As there are no therapeutic equivalents to Lysteda® for heavy menstrual bleeding, it is important for pharmacists to be able to counsel patients appropriately on the specific …

Effects Of Hormone Therapy On Cognition In Post-Menopausal Women, Jessica Langhals, Megan Meyer, Erica Schoenberger, Amanda Meyer, Kristen Finley Sobota

Pharmacy and Wellness Review

Menopause occurs as a result of decreased natural estrogen production by the body. A variety of short-term and long-term symptoms can occur during menopause, which may significantly impact a woman's daily life. Hormone therapy (HT) is commonly employed to alleviate these unwanted symptoms and to regain balance of hormone levels. Options include estrogen-only or estrogen-progestin combination therapy. While HT may help relieve symptoms such as cognitive decline caused by menopause, it also carries potential side effects. Although HT has shown a potential benefit in women with Alzheimer's disease (AD), overall outcomes measuring cognitive function improvement are inconclusive. Therefore, HT should …

Can Intraoperative Manometry Influence The Outcome Of The Surgical Treatment Of Achalasia?, Lucian Alecu, Iulian Slavu, Adrian Tulin, Daniela Mihaila, Robert Ivascu, Liliana Mirea

Journal of Mind and Medical Sciences

Introduction. Achalasia is defined as incomplete or even absent relaxation of the lower esophageal sphincter secondary to the chronic degeneration of unspecified etiology of the myenteric nerve plexus. Material and method. The retrospective study extended over 1 year. The collected variables were: age, sex, type of surgical intervention, intraoperative manometry results, and postoperative complications. Results. We identified 8 patients. The mean operative time was 100 minutes. The use of manometry determined an increase in time of 30 to 40 minutes. Manometry was successfully achieved in all cases, although in one case the sensor could not pass through the lower esophagus, …

Beta-Blockers In Cardiovascular Therapy: A Review, Camelia C. Diaconu, Dragos R. Marcu, Ovidiu G. Bratu, Ana Maria A. Stanescu, Gina Gheorghe, Andreea A. Hlescu, Dan L. Mischianu, Maria Manea

Journal of Mind and Medical Sciences

The role of beta-adrenergic receptor antagonists in cardiovascular therapy has been the subject of various studies over time, these agents representing one of the oldest class of drugs used for the treatment of cardiovascular diseases. Although beta-blockers have been excluded from guidelines as the first-line therapy in essential hypertension, they remain the first choice in patients with heart failure, coronary artery disease, and atrial fibrillation. In this article, we review the major clinical evidence for the use of beta-blockers in cardiovascular diseases. Several trials have demonstrated that beta-blockers reduce mortality in patients with heart failure with a reduced ejection fraction. …

Cartouches De Protection Respiratoire Contre Les Gaz Acides : Établissement Des Performances En Laboratoire Avec Le Dioxyde De Soufre, Ludovic Tuduri, Adrien Debernardi, Yves Cloutier, Brigitte Roberge, Jaime Lara

Rapports de recherche scientifique

L’exposition des travailleurs aux contaminants aéroportés doit être maîtrisée et maintenue en deçà des valeurs limites réglementaires. Lorsque l’ensemble des mesures administratives, d’ingénierie et de protection collective ne permet pas d’atteindre des niveaux d’exposition sans danger pour leur santé, les travailleurs concernés doivent être équipés d’appareils de protection respiratoire (APR). En l’absence de situations de danger immédiat pour la vie et la santé (DIVS), des APR à épuration d’air sont utilisés. Dans le cas des contaminants gazeux, ou des vapeurs, ces APR sont munis de cartouches remplies d’adsorbants. Se pose alors la question du temps de service de ces cartouches. …

State School Policies As Predictors Of Physical And Mental Health: A Natural Experiment In The Regards Cohort, Willa D. Brenowitz, Jennifer J. Manly, Audrey R. Murchland, Thu Thi Xuan Ngyuen, Sze Yan Liu, M Maria Glymour, Deborah A. Levine, Michael Crowe, Timothy J. Hohman, Carole Dufouil, Lenore J. Launer, Trey Hedden, Chloe W. Eng, Virginia G. Wadley, Virginia J. Howard

Department of Public Health Scholarship and Creative Works

We used differences in state school policies as natural experiments to evaluate the joint influence of educational quantity and quality on late-life physical and mental health. Using US census microsample data, historical measures of state compulsory schooling and school quality (term length, student-teacher ratio, and attendance rates) were combined via regression modeling on a scale corresponding to years of education (Policy Predicted Years of Education [PPYEd]). PPYEd values were linked to individual-level records for 8,920 black and 14,605 white participants aged 45+ in the REasons for Geographic and Racial Differences in Stroke study (2003-2007). Linear and quantile regression models estimated …

Presumed Diffuse Unilateral Subacute Neuroretinitis: A Review Supported By A Unique Case, Kirsti K. Ramirez Od, Joseph Pizzimenti Od, Jeannette Wong-Powell Od, Jeffrey Rabin Od

Optometric Clinical Practice

Diffuse unilateral subacute neuroretinitis (DUSN) is a rare, sight-threatening inflammatory condition caused by a nematode. It typically affects healthy children and young adults. Various nematodes have been implicated, including those that originate from dogs and raccoons. Late stage findings include optic nerve atrophy, retinal arterial attenuation, “retinitis pigmentosa-like” retinal pigmentary changes, and central and peripheral vision loss. We present a case study of long-standing DUSN. The combination of optical coherence tomography (OCT) and visual electrophysiology testing proved invaluable in establishing a presumptive diagnosis of this rare condition.

Welcome Letter Of Introduction To Our New Journal - Optometric Clinical Practice, Timothy Wingert Od

Optometric Clinical Practice

On behalf of the entire editorial board, Timothy Wingert, OD, dean at the University of the Incarnate Word - Rosenberg School of Optometry, welcomes you to the inaugural issue of Optometric Clinical Practice. (ISSN: 2575-7717)

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern: Explores Health and Wellbeing in the U.S. House Ball Community: A Systematic Review

Association Of Urine Levels Of C-Reactive Protein With Clinical Outcomes In Patients With Pneumonia: A Pilot Study, Subathra Marimuthu, Vidyulata Salunkhe, Stephen P. Furmanek, Leslie A Wolf

The University of Louisville Journal of Respiratory Infections

Finding relevant biomarkers as a potential predictor of severity for patients hospitalized with community acquired pneumonia (CAP), in addition to the clinical scoring system, could advance progress towards more effective patient management. The inflammatory marker, C-reactive protein (CRP), which is elevated in the pathogenesis of many infectious diseases, may be a key biomarker target for CAP. Previous studies have shown that serum CRP may be a useful diagnostic marker for pneumonia in hospitalized patients with acute respiratory symptoms. The main aims of this study were to determine the correlation between serum and urine CRP levels in hospitalized patients with CAP, …

Mitsui-7, Heat-Treated, And Nitrogen-Doped Multi-Walled Carbon Nanotubes Elicit Genotoxicity In Human Lung Epithelial Cells, Katelyn J. Siegrist, Steven H. Reynolds, Dale W. Porter, Robert R. Mercer, Alison K. Bauer, David Lowry, Lorenzo Cena, Todd A. Stueckle, Michael L. Kashon, John Wiley, Jeffrey L. Salisbury, John Mastovich, Kristin Bunker, Mark Sparrow, Jason S. Lupoi, Aleksandr B. Stefaniak, Michael J. Keane, Shuji Tsuruoka, Mauricio Terrones, Michael Mccawley, Linda M. Sargent

Public Health Sciences Faculty Publications

Background: The unique physicochemical properties of multi-walled carbon nanotubes (MWCNT) have led to many industrial applications. Due to their low density and small size, MWCNT are easily aerosolized in the workplace making respiratory exposures likely in workers. The International Agency for Research on Cancer designated the pristine Mitsui-7 MWCNT (MWCNT-7) as a Group 2B carcinogen, but there was insufficient data to classify all other MWCNT. Previously, MWCNT exposed to high temperature (MWCNT-HT) or synthesized with nitrogen (MWCNT-ND) have been found to elicit attenuated toxicity; however, their genotoxic and carcinogenic potential are not known. Our aim was to measure the genotoxicity …

Using Empirical And Theoretical Approaches To Control Outbreaks Of An Emerging Disease (Swimmer’S Itch) In The Midwest Of The U.S.A., Gregory J. Sandland, James Peirce

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Farm To School For All: Federal Farm To School Policy Under The Equity Lens, Chloe Marshall

Year on Climate Change: Events

This session explores federal child nutrition policy and how to apply an equity lens in advocacy using the National Farm to School Network's Racial and Social Equity Assessment tool.

Modeling Resilience In Resettled Syrian Refugees With Disabilities, Nicholas Sherwood

Biennial Conference: The Social Practice of Human Rights

Since 2011, the ongoing conflict in Syria has displaced millions of individuals, many of whom are now resettled across foreign borders. The US currently hosts 21,000 Syrian refugees, and of these, at least 5,000 have a form of disability. Furthermore, many US-based resettlement agencies currently experience strain providing the specialized care required by many of these resettled Syrian refugees with disabilities (RSRD) in large part due to austerity measures imposed by the US Federal government. This research project asks of RSRD themselves: given the limitations placed on your care providers, what personal sources of strength do you utilize when you …

Assessing Effectiveness Of A Novel Mid-Upper Arm Circumference Z-Score Tape In A Community Setting In Guatemala., Mikaela A. Miller, Kristen Mallory, Manolo Escobedo, Ana Cecilia Tarot, Susan M. Abdel-Rahman

Manuscripts, Articles, Book Chapters and Other Papers

Background: Mid-Upper Arm Circumference (MUAC) is an independent anthropometric measurement used to identify malnutrition in children. While much research has been dedicated to applying fixed estimates of MUAC to identify cases of malnutrition in children under 5 years of age, far less has been done with age-specific MUAC Z-score values across the continuum of age from birth through adolescence.

Methods: The present study examined the effectiveness of a novel MUAC Z-score tape, in the hands of community health volunteers, to identify children over the age of 5 who would benefit from nutritional rehabilitation. In January of 2019, 112 community health …

A Community-Based Survey To Assess Knowledge, Attitudes, Beliefs And Practices Regarding Herpes Zoster In An Urban Setting, Nour A. Baalbaki, Joseph P. Fava, Melanie Ng, Ezinwanne Okorafor, Asad Nawaz, Wesley Chiu, Abdulbaset Salim, Raymond Cha, Paul E. Kilgore

Department of Pharmacy Practice

Introduction: In the USA, nearly one in three people will experience herpes zoster (HZ) in their lifetime. Underserved communities may be at even higher risk due to several factors, including access to healthcare, education, and co-morbid conditions. The purpose of this study was to investigate current knowledge, attitudes, beliefs and practices (KABP) relative to HZ and HZ vaccines in a large urban city.

Methods: A cross-sectional KABP survey was conducted via in-person interview among 381 participants aged ≥ 50 years in Detroit, MI, USA, from June to August 2018. Survey results were stratified into two groups [< 60 and ≥ 60 years of age (YO)] for comparison.

Results: Of the …

Health Benefits Associated With An Employer-Sponsored Health Promotion Program With Device-Reported Activity, Ian Duncan, Wade Herndon, Xiyue Liao

Journal of Wellness

Background: As interest has grown in the effect of healthy behaviors on health outcomes, programs have been developed to incent healthy behavior. The growth of devices able to transmit information about program participant activities has allowed researchers to analyze physical activity (PA). We analyzed the relationship between positive changes in device-reported physical activity levels and changes in health-related variables in a longitudinal cohort of US based employees.

Methods: Exercise levels were measured and recorded by a device (such as a pedometer or heart-rate monitor) or gym visit and recorded by the health promotion program provider, The Vitality Group. The devices …

Effects Of Acute Physical Activity On Nih Toolbox-Measured Cognitive Functions Among Children In Authentic Education Settings, H. G. Calvert, J. M. Barcelona, D. Melville, L. Turner

University Author Recognition Bibliography: 2019

Introduction: Identifying a dose of physical activity (PA) that can improve cognitive function in children has important implications for school-day PA recommendations. Researchers and educators have interest in this link as it relates to both health and academic performance. This study examined the dose-response relationship between PA and improvement in cognition in a sample of fifth and sixth grade students.

Methods: Participants (n = 156) from eight classes each completed two of four different cognitive assessments on an iPad, both before and after exposure to one of four randomized, 10-min PA conditions (sedentary, light, moderate, and vigorous). Conditions …

Differences In Duration Of Untreated Psychosis For Racial And Ethnic Minority Groups With First-Episode Psychosis: An Updated Systematic Review And Meta-Analysis., Nicole Schoer, Chen Wei Huang, Kelly K. Anderson

Epidemiology and Biostatistics Publications

PURPOSE: Ethnic minority groups with early psychosis may have longer treatment delays, potentially leading to poorer outcomes. We updated a previous systematic review of the literature on racial and ethnic differences in duration of untreated psychosis (DUP) among people with first-episode psychosis.

RESULTS: Six of 17 studies described significant differences across aggregated racial groups; however, the pooled estimates did not show differences across groups. Additional data from this update allowed for disaggregated analyses, finding that Black-African groups have a shorter DUP, whereas Black-Caribbean groups have longer DUP, relative to White groups.

CONCLUSIONS: These findings highlight the importance of in-depth research …

Implementing Screening To Assess Readiness To Change In Overweight And Obese Patients At A Patient-Centered Medical Home, Jarrod Gant

Doctoral Projects

Obesity is at epidemic levels within the United States (U.S.), but the Southern U.S. has some of the most obese states. Mississippi (MS) is the most obese state in the country (Robert Wood Johnson Foundation, 2018). Factors such as diet, sedentary lifestyle, cultural influences, and socioeconomic status contribute to the state’s citizens being overweight and obese.

Contributing to the state’s obesity is the fact that MS has more people living in poverty than any other state (Center for American Progress [CAP], 2018). Lacking the ability to afford healthy foods and the ability to afford quality healthcare adds to the state’s …

Meeting Overview: Interferon Lambda - Disease Impact And Therapeutic Potential, Thomas R. O'Brien, Howard A. Young, Raymond P. Donnelly, Ludmila Prokunina-Olsson

United States Public Health Resources

A meeting entitled, "Interferon Lambda: Disease Impact and Translational Potential," was held on the campus of the National Institutes of Health in Bethesda, Maryland, on October 25-26, 2018. To our knowledge, this was the first meeting that focused exclusively on interferon lambda (IFN-λ). The meeting's purpose was to enhance interdisciplinary communication and promote new collaborations. The gathering brought together an international group of scientists from a wide range of disciplines. Sessions included: IFN-λ Biology, Therapy and Genetic Variation; IFN-λ and Hepatitis C Virus Infection; IFN-λ in Other Infections; and IFN-λ - Hepatic Fibrosis and Cancer. The next meeting on IFN-λ …

Vocal Hygiene For Musical Theatre Performers, Anne M. Koziara, Dr. Ron Scherer

Honors Projects

There have been numerous “do’s - and - don’t’s” vocal hygiene pamphlets made for voice users, however, a guide for vocal hygiene for musical theatre performers is not typically included in these pamphlets. Musical theatre performers differ from other professional voice users, because in addition to singing, they also have the taxing responsibilities of acting and dancing. As a result, many musical theatre performers have questions and often seem confused about what proper vocal hygiene should be for them. The goal of this honors project was to create an advisory brochure on vocal hygiene specifically for musical theatre performers. This …

Individual- And Community- Level Associations With Healthcare Utilization Among A Health System, Emergency Department Population, Carlene A. Mayfield

Theses and Dissertations

AIM: The primary aim of this study was to examine individual-level and community- level characteristics associated with ambulatory or primary care utilization, emergency department (ED) utilization, and ED charges among a sample of ED patients.

DESIGN AND SAMPLE: Data for this cross-sectional study were obtained from three distinct sources: (i) electronic medical records (EMR); (ii) billing records; and (iii) the 2013-2017 American Community Survey (ACS). The individual-level EMR and billing sample included all adults residing in Mecklenburg County, North Carolina who visited an Atrium Health ED in 2017. The ACS sample included population and demographic estimates from Mecklenburg County’s 27 …