Public Health Commons^™

Healing Right Way: A Stepped Wedge Cluster Randomised Controlled Trial Aiming To Enhance Quality Of Life For Aboriginal Australian Survivors Of Stroke And Traumatic Brain Injury, Elizabeth Armstrong, Tapan Rai, Judith M. Katzenellenbogen, Sandra J. Thompson, Meaghan Mcallister, Natalie Ciccone, Deborah Hersh, Leon Flicker, Dominique A. Cadilhac, Erin Godecke, Graeme J. Hankey, Neil Drew, Colleen Hayward, Deborah Woods, Mel Robinson, Ivan Lin, Sanita Kratina, Jane White, Juli Coffin

Research outputs 2022 to 2026

Objective: To determine the effect of cultural security training (CST) for health professionals and access to an Aboriginal Brain Injury Coordinator (ABIC) for Aboriginal Australians with stroke or traumatic brain injury (TBI). Design: A stepped wedge cluster randomised controlled trial; the intervention package consisted of CST for hospital professionals and 6-month access to ABICs providing education, support, liaison and advocacy; the commencement order of the intervention phase was randomised. Setting: Four urban and four rural hospitals in Western Australia, 2018–2022. Participants: Aboriginal adults ≥ 18 years hospitalised with stroke or TBI. Main Outcome Measures: Primary outcome was quality of life …

Knowledge + Innovation = Power: A Protocol For Implementing Aboriginal Data Sovereignty In An Aboriginal Medical Service For Service Delivery Reform, Emma Haynes, Lesley Nelson, Heather D'Antoine, Judith Katzenellenbogen, Elizabeth Armstrong, Lindey Andrews, Jasmin Brown, Nicole Bowser, Roz Walker, Ingrid Stacey, Jessika Purnomo, Dawn Bessarab

Research outputs 2022 to 2026

Context Comprehensive Primary Health Care (CPHC) is an interconnected, holistic, and strengths-based health and wellbeing approach fundamental to Aboriginal Community Controlled Health Organisations (ACCHOs) in Australia. However, policy and funding trends increasingly threaten the capacity of ACCHOs to deliver CPHC by imposing burdensome administrative and accountability requirements. A central constraint is the marginalisation of culturally informed data measures and tools that could enable improved development, implementation, evaluation and reporting of CHPC services and programs. To mitigate this, ACCHOs must be enabled to take charge of collecting and using meaningful data to increase self-determination and drive impactful policy and service delivery. …

Exploring Preferences For Interventions To Increase Active School Transportation Among Children And Adolescents In Australia, Anna Gannett, Paula Hooper, Julie Saunders, Gina Trapp

Research outputs 2022 to 2026

Introduction: The observed decline in children's active school transport (AST) across numerous countries over recent decades necessitates targeted, multi-level interventions to reverse this trend. However, data on young people's preferred AST interventions is lacking. This study aimed to explore children's preferences for AST interventions and assess differences between AST users and non-users among primary and secondary school students. Methods: In 2023, a cross-sectional survey was conducted in Perth, Western Australia with n = 742 primary school students from 23 schools and n = 412 secondary school students from 9 schools. The survey assessed AST frequency, preferred transport mode, and AST …

Implementation Fidelity Of A Smartphone Application For Population-Based General Movement Assessment: The Early Moves Study, Caroline F. Alexander, Sarah E. Hall, Alison Salt, Alicia J. Spittle, Catherine Morgan, Tiffany Grisbrook, Alishum Ali, Natasha Amery, Sue Anne Davidson, Ashleigh Thornton, Mary Sharp, Emily Young, Robert S. Ware, Desiree Silva, Roslyn Ward, Nadia Badawi, Samudragupta Bora, Roslyn N. Boyd, Susan Woolfenden, Catherine Elliott, Jane Valentine

Research outputs 2022 to 2026

Objective: To describe the infant and maternal characteristics of the Early Moves cohort and to assess representativeness to the general population, and to evaluate the implementation fidelity of an application-based collection of General Movement Assessment (GMA) videos at writhing and fidgety age. Study design: Prospective observational study. Mothers who had recently delivered or were enrolled to deliver at maternity hospitals in Perth, Western Australia, were recruited from November 2019 to December 2023. Sociodemographic and infant clinical characteristics were extracted from hospital records. Parents were invited to record GMA videos using the Baby Moves smartphone application, which were assessed for scorability …

Tissue-Specific Distribution Of Microplastics In Human Blood And Carotid Plaques: A Paired Sample Analysis, Cancan Cui, Zheng Guo, Yanxi Liu, Ning Han, Jiayin Song, Yuanmei Chen, Yulu Zheng, Chen Sheng, Lois Balmer, Haibin Li, Rui Liu, Lin Liu, Jianshi Du, Zhiyuan Wu

Research outputs 2022 to 2026

Backgrounds: Microplastics (MPs) have been increasingly detected in human tissues, raising concerns about their role in cardiovascular disease. However, their distribution in matched blood and vascular tissues, such as atherosclerotic plaques, remains poorly understood. Methods: Paired blood and carotid plaque samples were analyzed for 12 polymer types of MPs using pyrolysis–gas chromatography–mass spectrometry among twenty patients undergoing carotid endarterectomy. Results: The mean concentration of total MPs was 75.2 μg/g in blood and 432.9 μg/g in plaque. Polyethylene (PE) dominated blood samples (46.5 %), followed by polyvinyl chloride (PVC, 16.8 %) and styrene-butadiene rubber (SBR, 16.3 %). In plaques, MPs were …

Occupational Exposure To Diesel Particulate Matter In Western Australian Mining: A Retrospective Analysis And Challenges To Future Compliance, Matthew Oosthuizen, Kerry Staples, Adelle Liebenberg, Kiam Padamsey, Marcus Cattani, Andy Mccarthy, Jacques Oosthuizen

Research outputs 2022 to 2026

De-identified diesel particulate matter (DPM) exposure data (n = 24,459) was obtained from the Western Australian mining regulator to assess compliance with the current Workplace Exposure Standard (WES) of 0.1 mg/m³, measured as submicron elemental carbon, and a proposed limit of 0.01 mg/m³, assessed as respirable elemental carbon. R and R-Studio were used to generate summary statistics comparing compliance to the current and proposed limits, stratified by industry and occupational groups. To examine temporal trends, a zero-adjusted gamma model was used to assess whether expected sample means changed over the past ten years, using commodity and …

Digital Tools To Promote Or Measure Health Literacy In Children Aged 3–5 Years: Scoping Review, Caron Molster, Jennifer Irvine, Amanda Devine, Ruth Wallace, Lennie Barblett, Leesa Costello

Research outputs 2022 to 2026

Health literacy is a determinant of health that should be promoted and measured in early childhood. In the era of digitalization, this could involve digital platforms. However, little knowledge exists on the extent, range, and nature of literature on digital tools for promoting or measuring young children’s health literacy. Addressing this gap, a scoping review was undertaken to explore what digital health literacy tools for children aged 3–5 years could be identified in the literature, what their key features were, how they were designed, whether children were codesigners, and whether the tools had been evaluated. Eligibility criteria included the literature …

Restricting Outdoor Advertising Of Unhealthy Food: Can Australia's Food Category-Based Classification System Be Applied Consistently?, Clare Whitton, Frith Klug, Alexia Bivoltsis, Georgina S.A. Trapp, Claire E. Pulker

Research outputs 2022 to 2026

Most outdoor food advertising (e.g. billboards and bus stops) features foods that are considered unhealthy. The most important technical challenge when designing policies to restrict unhealthy outdoor food advertising is defining 'unhealthy food'. To date, most restriction policies have used nutrient profiling models (i.e. foods are classified according to their nutritional composition) to determine which foods and beverages may be advertised. In Australia, state governments have endorsed a food category-based classification system, with no prescribed nutrient limits, which may create ambiguity when multiple users are identifying food advertisements to be restricted. This study aimed to assess the consistency of decisions …

Welding Fume In The Western Australian Mining Industry: Impact Of A Change To The Workplace Exposure Standard, Matthew Oosthuizen, Kerry Staples, Adelle Liebenberg, Kiam Padamsey, Marcus Cattani, Andy Mccarthy, Jacques Oosthuizen

Research outputs 2022 to 2026

The aim of this study was to analyse the Western Australian (WA) Safety Regulatory System (SRS) database to assess compliance of the WA mining sector regarding workers exposure to welding fumes and to identify trends over time. De-identified data analysed to assess the impact of reducing workplace exposure standards (WES) for general welding fumes on industry compliance. Historical trend analysis shows a shift from 100% compliance to 100% non-compliance, based on mean values and 95% confidence intervals, with exposure levels remaining consistent over time. These findings highlight the need for current, innovative engineering solutions, and raise questions about the validity …

A Global Movement Takes Shape – Physical Activity, Health, And The New Era Of Responsibility: “Global Alliance For Promotion Of Physical Activity”, J. M. Steinacker, W. Van Mechelen, C. Joisten, S. Zanuso, C. A. Jaworski, Y. P. Pitsiladis

Research outputs 2022 to 2026

No abstract provided.

Clostridioides (Clostridium) Difficile In Children And Adolescents In The Community In Cambodia, Lengsea Eng, Paul Turner, Kefyalew Addis Alene, Deirdre A. Collins, Su Chen Lim, Pisey Tan, Sona Soeng, Dylorng Hun, Sotera Yohn, Sarim Vong, Archie C.A. Clements, Thomas V. Riley

Research outputs 2022 to 2026

Background: Clostridioides (Clostridium) difficile transmission between community and healthcare settings has been increasingly reported. We aimed to identify the prevalence and molecular epidemiology of C. difficile colonising adolescents and non-hospitalised children in Cambodia. Methods: Stool samples were collected from 266 students at the University of Health Sciences (UHS) in Phnom Penh, between July and August 2022, and 246 children ≥1 year old visiting the outpatient department (OPD) at Angkor Hospital for Children in Siem Reap, between January and August 2022. C. difficile culture, toxin gene detection and PCR ribotyping were performed. Results: Overall, C. difficile was recovered from 07/266 specimens …

Caring For Home Care Workers: Health And Safety Hazards, Harms And Risk Factors, Denise M. Jepsen, Sanetta Henrietta Johanna Du Toit, Toni Robyn Barker, Saul Wodak, Erin Lawn, Tash Freeburn, Josh Rhee, Carmel Laragy, Elizabeth Convery

Research outputs 2022 to 2026

Home care workers support the growing number of older adults or people with disabilities who are living at home in their own private residences. The complex and varied work health and safety (WHS) hazards these workers face on the job include both physical and psychosocial harms. While physical WHS hazards in this sector have been articulated, there is an urgent need to update, understand and address psychosocial risks such as verbal abuse and sexually inappropriate behaviour and bullying, particularly when perpetrated by clients. This study sought to identify the range of WHS hazards and harms that home care workers face …

Navigating Child Oral Health In Western Australia: A Caregiver's Perspective, Lesley Andrew, Elizabeth Wenden, Mohamed Estai, Ruth Wallace

Research outputs 2022 to 2026

Background: Early childhood caries (ECC) is the most common chronic health condition among Australian preschool-aged children. Untreated, ECC can affect children's physical and emotional health and future social opportunities. ECC is largely preventable through primary caregivers' correct understanding of oral health promoting diets, oral hygiene practices and dental service engagement. The study aim is to explore Western Australian (WA) primary caregivers' child oral health knowledge, experience and practices. The Fisher-Owens socioecological model of child oral health was applied across the study to structure and interpret the findings across the complex, interactive sociocultural influences on child oral health. Methods: The mixed-methods …

Foundations And Strategic Vision Of The Canadian Translational Geroscience Network, Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, Gustavo Duque

Research outputs 2022 to 2026

Geroscience is an emerging interdisciplinary field that explores the biological connections between aging and the development of chronic diseases, with the ultimate goal of identifying interventions to extend healthspan and delay age-related conditions. Recognizing the growing importance of this field, the Canadian Translational Geroscience Network (geroscience.ca) was officially launched during a conference held in Montreal on September 5-6, 2024. Building on the momentum of successful Geroscience meetings in Toronto and Montreal in 2023, this milestone event marked a transformative step forward for geroscience in Canada. This event brought together key stakeholders, including the Canadian Frailty Network (CFN), the Canadian Institutes …

Models Of Care For Indigenous Children In Rural And Remote Settings: A Global Scoping Review, Joseph Freeman, Thomas Stubbs, Verity Chadwick, Anita Pickard, Tuguy Esgin, Elizabeth J. Elliott, Alexandra Martiniuk

Research outputs 2022 to 2026

Indigenous communities internationally have demonstrated remarkable strength despite significant challenges. Health disparities among Indigenous peoples persist due to historical injustices and ongoing racial discrimination, not inherent vulnerabilities. Disparities are rooted in a legacy of colonisation, systemic exclusion, and socio-economic inequities impacting access to healthcare, education, and employment. Preliminary searches show limited literature on models of care for remote living Indigenous children. This review aimed to identify internationally, effective models of care for Indigenous children in rural and remote areas. A scoping review was conducted, analysing literature on models of care for remote Indigenous children. This study followed the JBI’s Scoping …

The Artichoke Model: A Conceptual Framework For Positive Food Environments In Early Childhood Education And Care (Ecec) Settings, Ros Sambell, Audrey Elford, Tori Overstone, Rebecca Byrne, Kirsty Elliott, Sandra Vale, Penelope Love, Lisa Vincze, Leanne Elliston, Fiona Nave, Janny Goris, Emma Esdaile, Amanda Devine

Research outputs 2022 to 2026

The Artichoke Model is a conceptual framework developed to support the understanding of the breadth and influence of food environments in Early Childhood Education and Care (ECEC) settings. It identifies twelve interrelated components spanning food provision, mealtime practices, curriculum integration, staff capacity, family engagement, and systemic enablers such as policy, equity, and environmental sustainability. Represented visually as an artichoke with the child at its centre, the model encourages holistic analysis, recognising that sustainable change requires the interconnected operation of all components, rather than isolated interventions. The Artichoke Model is intended as a tool for researchers, policymakers, and advocates to guide …

Leadership And Capacity Building In International Osteopathic Research: Introducing Strengthening Osteopathy Leadership And Research (Solar) Program, Cindy Mcintyre, Gopi Anne Mcleod, Ana Paula Antunes Ferreira, Francesco Cerritelli, Jerry Draper-Rodi, Jack Feehan, Michael Fleischmann, Kesava Kovanur Sampath, Chantal Morin, Lee Muddle, Niklas Sinderholm Sposato, Oliver P. Thomson, Loïc Treffel, Nicholas Tripodi, Brett Vaughan, Amie Steel, Jon Adams

Research outputs 2022 to 2026

Research evidence has become the foundation of modern health services. Health professionals rely on sound research to provide safe and effective care for patients, for the development of innovative diagnostic and treatment practices and to develop policies supporting the provision of optimal healthcare. Osteopathy is an established profession with an emerging research evidence base. The Strengthening Osteopathic Leadership and Research (SOLAR) program is a recent international initiative aiming to further build the evidence base and research capacity of the osteopathy profession. The program was developed by The Australian Research Consortium in Complementary and Integrative Medicine (ARCCIM) at the University of …

Consumers' Perspectives On The Design Of A New Digital Frailty Education Course, ‘Focus On Frailty’: A Qualitative Co-Design Study, Kristiana Ludlow, Benignus Logan, Jhalak Arora, Sarah Martin, Elizabeth Miller, Ruth E. Hubbard, Nicola Warren, Olivia Gallagher, Rosemary Saunders

Research outputs 2022 to 2026

Introduction: Frailty-focused care in hospitals is hindered by systemic barriers, ageism and stereotypes about older adults and frailty. There is a need for frailty education to increase healthcare professionals' and students' understanding of frailty. Objective: As part of a larger study to co-design a new digital frailty education course, ‘Focus on Frailty’, this study aimed to explore consumers' and caregivers' perspectives on (i) how frailty and older adults should be represented in frailty education and (ii) what healthcare professionals should be taught about caring for older adults and people who are frail in hospitals. Design: This was a qualitative co-design …

Changes In The Contributions Of Risk Factors To Under-Five Mortality In Low- And Lower-Middle-Income Countries (1997-2022): An Analysis Of Demographic And Health Survey Data, Bereket Kefale, Jonine Jancey, Amanuel T. Gebremedhin, Gavin Pereira, Gizachew A. Tessema

Research outputs 2022 to 2026

Background: Under-five mortality (U5M) is a critical public health challenge in low- and lower-middle-income countries (LLMICs), where over 90% of global deaths occur. Despite progress, the changing contributions of risk factors to U5M in LLMICs remain unexplored.

Mrthods: We analysed Demographic and Health Survey (DHS) data from 24 LLMICs across two periods: 1997-2005 and 2016-2022. We included 139,890 live births in 1997-2005 and 319,034 in 2016-2022. A mixed-effects robust Poisson regression model with a log link function was employed to identify risk factors of U5M in each period. Population-attributable fractions (PAFs) were calculated and compared to investigate changes in the …

Navigating Travel Therapy: Balancing Benefits And Risks For Optimal Wellness, Fangli Hu, Jun Wen, Wei Wang

Research outputs 2022 to 2026

This research note examines travel therapy as a novel healthcare approach in which positive travel experiences serve to promote well-being. It emphasizes the need for a balanced assessment of the benefits and risks associated with travel therapy, offering insights into this practice's evolving roles in the health and wellness domains.

A Multivariate Analysis Of Reported Quality Of Life Among Medical Students In Jordan Using The Whoqol-Bref, Mohammad Hamad, Saba Al Smadi, Diana Arabiat

Research outputs 2022 to 2026

BACKGROUND: Low quality of life (QoL) in university students is often associated with unhealthy lifestyle and negative impacts on students' ability to learn and succeed. To date, no research has examined the QoL of medical students in Jordan or the demographic factors that may associate with lower QoL. MATERIALS AND METHODS: A quantitative, cross-sectional study with a descriptive design was chosen for this study. Participants were 512 medical students from one public university in Jordan. The Arabic version of the World Health Quality of life-brief survey (WHOQOL-BREF) was used to collect data online from students. RESULTS: Regarding the overall QoL, …

Cocreating A Programme To Prevent Injuries And Improve Performance In Australian Police Force Recruits: Consumer, Industry Partner And Researcher Involvement Protocol, Myles Calder Murphy, Andrea R. Bruder, Vanessa R. Sutton, Garth M. Allen, Andrea C.M. Mosler, Jonathan M. Hodgson, Simone Radavelli-Bagatini, Evert L. Verhagen, Joanne Kemp, Caroline Jones, Joletta Belton, Debra Langridge

Research outputs 2022 to 2026

We are conducting a research program to cocreate, implement and evaluate an injury prevention intervention for the Western Australia (WA) Police Force Recruit Training Academy. This programme of research has three primary phases: (1) cocreate an injury prevention intervention for the WA Police Force with WA Force recruits, WA Police Force staff, health professionals and injury prevention experts, (2) implement the injury prevention intervention into WA Police Force Recruit training and (3) evaluate the reach, effectiveness, adoption, implementation and maintenance of the injury prevention intervention. Our research programme includes the involvement of consumers, industry partners and researchers. To ensure collaboration …

Lifesaving Cardiopulmonary Resuscitation: A Pilot Evaluation Of A Targeted Educational Intervention To Improve Cardiopulmonary Resuscitation Provision In Volunteer Surf Lifesavers, David Reid, Katie M. Dixon, Leesa Equid, Chris Jacobson, Jasmin C. Lawes, Tracey Hare-Boyd, Andrew Chubb, Michelle Murphy, Kane Treloar, Pamela Simon, Ned Douglas

Research outputs 2022 to 2026

Background: Approximately 26,000 out-of-hospital cardiac arrests occur in Australia each year, and only 13% of patients survive their event and return home. Survival variability from out-of-hospital cardiac arrests can be explained by a range of factors. Cardiopulmonary resuscitation (CPR) education quality-improvement programs focusing on identified elements of basic life support provision in concert with resuscitation system interventions have been associated with significant improvements in survival after cardiac arrest. Surf Life Saving Australia members respond to approximately 65 cardiac arrests per year in the community while on duty and have successfully resuscitated many beachgoers over the years. In addition to this, …

Codesigning Training For Health Providers To Improve Detection And Response To Elder Abuse, Bianca Brijnath, Marina G. Cavuoto, Peter Feldman, Briony Dow, Josefine Antoniades, Joan Ostaszkiewicz, Sigrid Nakrem, Catriona Stevens, Patricia Reyes, Gianna Renshaw, Micah D.J. Peters, Andrew Gilbert, Elizabeth Manias, Duncan Mortimer, Joanne Enticott, Claudia Cooper, Cheryl Durston, Brenda Appleton, Meghan O'Brien, Marion Eckert, Simona Markusevska

Research outputs 2022 to 2026

Background and Objectives: Screening for elder abuse can improve detection, but many health providers lack the necessary skills and confidence. To address this, training for health providers on elder abuse screening was codesigned as part of a trial aimed at improving elder abuse detection and response. Research Design and Methods: Between March and April 2023, 7 health providers and 10 older people and family carers participated in 2 national Australian online codesign workshops. Using the World Café method, discussions focused on what knowledge and skills health providers needed for screening; clinical and social issues affecting screening and referral; and support …

Impact Of Changes To International Commission On Radiological Protection Models On Occupational Thorium Ore Dust Intake, Gregory S. Hewson, Martin I. Ralph, Marcus Cattani

Research outputs 2022 to 2026

Workers involved in mining and processing naturally occurring radioactive materials (NORMs) are potentially exposed to dust containing alpha particle emitters. The objective of this study is to summarize the key impacts of the latest International Commission on Radiological Protection (ICRP) biokinetic model for thorium ore dust intake and to identify model parameters that require further investigation. The dosimetric significance of thorium ore dust exposure has varied widely over time owing to progressive changes in the inhalation dose coefficients. These changes had a significant influence on radiation protection practices in the Western Australian mineral sand industry, including research initiatives and implementation …

Opportunistic Measurement Of Sagittal Abdominal Diameter With Bone Densitometry Predicts Death And Cardiovascular Events, William D. Leslie, Fatima Zarzour, Lisa M. Lix, Neil Binkley, Joshua R. Lewis, John T. Schousboe

Research outputs 2022 to 2026

Supine sagittal abdominal diameter (SAD), also known as abdominal height, has been proposed as a simple measure for assessing abdominal adiposity. We aimed to determine whether SAD from DXA performed for osteoporosis assessment predicts major adverse cardiovascular events (MACEs) using the population-based DXA registry for the Province of Manitoba, Canada. The study population comprised 72 974 individuals aged 40 yr and older with baseline DXA assessment between February 1999 and March 2018. Incident MACE (composite of all-cause mortality, acute myocardial infarction [MI], non-hemorrhagic stroke) was ascertained from linked healthcare databases. During mean 8.4 yr follow-up (611 862 person-years), 14 457 …

Kaat Koort: Study Protocol For A Pragmatic Randomized Controlled Trial Of A Multifactorial, Multidisciplinary Aboriginal Health Practitioner-Led Aboriginal Dementia Prevention Intervention, Carrington C.J. Shepherd, Melissa A. Dunham, Lina Gubhaju, Karen E. Lamb, Digsu N. Koye, Phoebe Fitzpatrick, Emily Banks, Kaarin J. Anstey, Melinda Carrington, Daniel Mcaullay, Ofra Kalter-Leibovici, Grace Joshy, Lesley Nelson, Jason Agostino, Ellie Paige, Kathleen Abu-Saad, Elise Alexander, Rona Macniven, Kelsey Griffen, Fiona Collins, Salena Linforth-Milham, Dolores Gilbert, Cindy Prior, Sadia Rind, Richelle Douglas, Sandra Eades

Research outputs 2022 to 2026

Background: Limited available data indicate that dementia prevalence rates among Aboriginal and Torres Strait Islander (hereafter Aboriginal) peoples are 3–5 times higher than the overall Australian population. Effective, pragmatic and scalable interventions are urgently required to address this disproportionate burden of dementia in Aboriginal populations. Methods: Kaat Koort is a pragmatic two-arm parallel-group randomized controlled trial which will recruit a sample of 354 participants from two Aboriginal community-controlled health services in the south-west of Western Australia. Eligible participants are aged 35–60 years with risk factors for cardiovascular disease. Participants will be randomized in a 1:1 ratio to receive either a …

Changing Age Profile And Incidence Of Injecting Drug Use Initiation Among People In Australia Who Inject Drugs: Evidence From Two National Repeated Cross-Sectional Studies, Olivia Price, Lisa Maher, Amy Peacock, Farzaneh Zolala, Louisa Degenhardt, Paul Dietze, Sarah Larney, Seraina Agramunt, Samantha Colledge-Frisby, Bradley Mathers, Dan Lewer, Rachel Sutherland

Research outputs 2022 to 2026

Background: The age of people who inject drugs appears to be increasing in some high-income countries. We aimed to explore trends in the age of people injecting and recently starting to inject drugs in Australia, and to model incidence of initiation over time. Methods: We obtained data from the Illicit Drug Reporting System (IDRS) and the Australian Needle Syringe Program Survey (ANSPS), which comprise annual cross-sectional surveys with people who inject drugs (2000–2019). Outcome measures were current age, age of initiation, and time since initiation (both surveys), and drug first injected (IDRS only). We estimated time trends in age using …

Sedentary Leisure Behaviour, Physical Activity, And Gastroesophageal Reflux Disease: Evidence From A Mendelian Randomization Analysis, Shan Lu, Yahong Zhu, Mingyu Cui, Zheng Guo, Xingang Li, Ying Song

Research outputs 2022 to 2026

Background and Aims: Gastroesophageal reflux disease (GERD) is common worldwide. Although associations between sedentary behaviour (LSBs), physical activity (PAs), and GERD have been reported, their causal relationships remain unclear. This study uses Mendelian randomization (MR) to examine these associations with GERD. Methods: Genetic instruments from the UK Biobank and other consortia were utilized to assess the causal relationship between LSBs, PAs, and GERD. Causal analyses employed inverse variance weighted (IVW), weighted-median (WM), and MR-Egger regression. Sensitivity analyses included Cochran's Q test, MR-Egger intercept test, leave-one-out analysis, and funnel plot assessment. Outliers were detected using MR-PRESSO and Radial MR. A risk …

Thorium Ore Dust Research Applicable To Mineral Sands Industry Workers, Gregory S. Hewson, M. I. Ralph, M. Cattani

Research outputs 2022 to 2026

Historically, radiation exposure to mineral sands workers arose primarily from intake of thorium associated with monazite dust generated in mineral separation plants. Research investigations in the 1990s provided greater insight into the characteristics of inhaled thorium ore dust and bioassay studies inferred that some workers had accumulated significant lung burdens of thorium. Recent changes to biokinetic models have increased the radiation dose assessed to arise from thorium intake, raising questions on the appropriateness of current assumptions used in exposure assessment and feasibility of further bioassay research. Past radiation research undertaken in the Western Australian mineral sands industry is summarised and …