Public Health Commons^™

Exercise And Physical Activity In The Prevention And Treatment Of Atherosclerotic Cardiovascular Disease: A Statement From The Council On Clinical Cardiology (Subcommittee On Exercise, Rehabilitation, And Prevention) And The Council On Nutrition, Physical Activity, And Metabolism (Subcommittee On Physical Activity), Paul D. Thompson, David Buchner, Ileana L. Piña, Gary J. Balady, Mark A. Williams, Bess H. Marcus, Kathy Berra, Steven N. Blair, Fernando Costa, Barry Franklin, Gerald F. Fletcher, Neil F. Gordon, Russell R. Pate, Beatriz L. Rodriguez, Antronette K. Yancey, Nanette K. Wenger

Faculty Publications

No abstract provided.

Transmission Of Mycobacterium Tuberculosis Associated With Failed Completion Of Treatment For Latent Tuberculosis Infection - Chickasaw County, Mississippi, June 1999-March 2002, T. Chamblee, D. Hartley, M. Holcombe, K. Parham, P. Upchurch, R. M. Webb, Alyssa G. Robillard, L. Diem, B. Metchock, N. Deluca, P. D. Mcelroy, T. Navin, W. Walton, P. K. Dewan

Faculty Publications

During June 1999-March 2002, a total of 16 tuberculosis (TB) cases were reported from Chickasaw County, Mississippi (2000 population: 19,440), corresponding to annual TB incidences of 20.5-27.6 cases per 100,000 population. In comparison, annual TB incidences for Mississippi during the same period decreased from 7.8 to 5.4 cases per 100,000 population. This report summarizes the results of an investigation of the patients and their contacts and demonstrates the need for strategies to increase the proportion of infection contacts that successfully complete treatment for latent TB infection (LTBI).

Utilization Of Algal And Bacterial Extracellular Polymeric Secretions (Eps) By The Deposit-Feeding Brittlestar Amphipholis Gracillima (Echinodermata), D. L. Hoskins, S. E. Stancyk, Alan W. Decho

Faculty Publications

Like many deposit-feeding organisms, the burrowing brittlestar Amphipholis gracillima feeds on particulate organic matter in surface sediments. Microbial exopolymeric secretions (EPS) are carbohydrate-enriched polymers produced by microalgae and bacteria that bind aggregates and form dense biofilms near the sediment-water interface. EPS are assimilable by some benthic infauna and may be utilized as a significant carbon source. EPS are absorbed by some deposit-feeders, including a holothurian, and may be supplemental sources of nutrition. The burrowing brittlestar A. gracillima is a deposit-feeder that was used in a mass balance approach to model the incorporation of radiolabeled EPS by bottom feeders. Brittlestars were …

Urinary Excretion Of Dithiocarbamates And Selfreported Cruciferous Vegetable Intake: Application Of The ‘Method Of Triads’ To A Foodspecific Biomarker, Jay H. Fowke, James R. Hébert, Jed W. Fahey

Faculty Publications

Objective: Greater intake of Cruciferous vegetables (e.g. broccoli) may prevent cancer at several sites. Urinary excretion of isothiocyanate conjugates (dithiocarbamates, DTC) provides a specific biomarker of Cruciferous vegetable consumption suitable for epidemiological investigations. However, no gold-standard referent is available for evaluating urinary DTC levels as an estimator of Cruciferous vegetable consumption. We compared urinary DTC levels to intake as measured by two selfreported dietary assessment techniques. Design: Cruciferous vegetable consumption was measured before and after a behavioural dietary intervention using multiple 24-hour recalls (24HR), a foodcounting questionnaire (VFQ) and urinary DTC excretion levels. Analysis included a structural equation approach (Method …

Activity Patterns And Correlates Among Youth: Differences By Weight Status, Wendell C. Taylor, James F. Sallis, Marsha Dowda, Patty S. Freedson, Karen Eason, Russell R. Pate

Faculty Publications

The purposes of the study were to assess differences in physical activity levels and correlates of physical activity among overweight (‡ 85th percentile of body mass index for their sex and age) and non-overweight (< 85th percentile) youth. The sample included 509 seventh through twelfth graders. Activity was measured by a 7-day, 46-item activity checklist. Overweight girls were more sedentary than non-overweight girls (p<.03), and non-overweight girls engaged in more vigorous physical activity than overweight girls (p<.03). For boys, there were no significant differences in activity. The regression analyses for vigorous activity yielded the largest total R²'s (R²=.049 for overweight and R²=.27 for non-overweight.) The significant factor for overweight youth was greater athletic coordination (p<.01). For non-overweight youth, the significant factors were greater family support (p<.05), greater peer support (p<.001), fewer barriers (p<.03), and greater athletic coordination (p<.01). Correlates of physical activity vary by weight status of young people.

Associations Between Cardiorespiratory Fitness And C-Reactive Protein In Men, Timothy S. Church, Carolyn E. Barlow, Conrad P. Earnest, James B. Kampert, Elisa L. Priest, Steven N. Blair

Faculty Publications

Objective - This study examined the association between cardiorespiratory fitness and C-reactive protein (CRP), with adjustment for weight and within weight categories.

Methods and Results - We calculated median and adjusted geometric mean CRP levels, percentages of individuals with an elevated CRP (≥2.00 mg/L), and odds ratios of elevated CRP across 5 levels of cardiorespiratory fitness for 722 men. CRP values were adjusted for age, body mass index, vitamin use, statin medication use, aspirin use, the presence of inflammatory disease, cardiovascular disease, and diabetes, and smoking habit. We found an inverse association of CRP across fitness levels (P for …

Aha Guidelines For Primary Prevention Of Cardiovascular Disease And Stroke: 2002 Update - Consensus Panel Guide To Comprehensive Risk Reduction For Adult Patients Without Coronary Or Other Atherosclerotic Vascular Diseases, Thomas A. Pearson, Steven N. Blair, Stephen R. Daniels, Robert H. Eckel, Joan M. Fair, Stephen F. Fortmann, Barry A. Franklin, Larry B. Goldstein, Philip Greenland, Scott M. Grundy, Yuling Hong, Nancy Houston-Miller, Ronald M. Lauer, Ira S. Ockene, Ralph L. Sacco, James F. Sallis, Sidney C. Smith Jr., Neil J. Stone, Kathryn A. Taubert

Faculty Publications

No abstract provided.

Prevention Conference Vi: Diabetes And Cardiovascular Disease - Writing Group Iii: Risk Assessment In Persons With Diabetes, Rita F. Redberg, Philip Greenland, Valentin Fuster, Kalevi Pyörälä, Steven N. Blair, Aaron R. Folsom, Anne B. Newman, Daniel H. O'Leary, Trever J. Orchard, Bruce Psaty, J. Sanford Schwartz, Rodman D. Starke, Peter W. F. Wilson

Faculty Publications

No abstract provided.

Dietary Exposures And Oral Precancerous Lesions In Srikakulam District, Andhra Pradesh, India, James R. Hébert, Prakash C. Gupta, Ramesh B. Bhonsle, Hemali Mehta, Wei Zheng, Maureen Sanderson, Jane Teas

Faculty Publications

Objective: To test the effect of dietary nutrients on oral precancerous lesions in a reverse-smoking (i.e. smoking with the glowing end inside the mouth) population in South India. Design: Case–control. Cases with precancerous lesions were matched to an equal number of lesion-free controls matched on age (^5 years), sex and village. All subjects used tobacco in some form. Dietary data were obtained using an intervieweradministered food-frequency questionnaire, designed for use in this population. All interviews were conducted blinded to the disease status of the subject. Data were analysed using logistic regression. Setting: Nineteen rural villages in Srikakulam District, Andhra Pradesh. …

Correlates Of Vigorous Physical Activity For Children In Grades 1 Through 12: Comparing Parent-Reported And Objectively Measured Physical Activity, James F. Sallis, Wendell C. Taylor, Marsha Dowda, Patty S. Freedson, Russell R. Pate

Faculty Publications

Correlates of physical activity were examined in young people in grades 1 through 12, and analyses were conducted separately for eight age/grade and sex subgroups. Twenty-one explanatory variables were assessed by parental report. Physical activity was assessed in 781 young people via parent report, and 200 wore an accelerometer for seven days. Between 11% and 36% of parent-reported child vigorous physical activity was explained. The most consistent correlates were peer support and use of afternoon time for active rather than sedentary recreation. Peer support was the only significant correlate of objectively monitored activity in multiple subgroups.

Descriptive Epidemiology Of Body Mass Index Of An Urban Adult Population In Western India, H. C. Shukla, P. C. Gupta, H. C. Mehta, James R. Hébert

Faculty Publications

Study objective: To describe height, weight, and body mass index (BMI) of the adult urban population in Mumbai, western India and to estimate the prevalence and severity of thinness and overweight in this population. To describe the association of BMI with education, age, and tobacco habits in an urban Indian population. Design: Cross sectional representative survey of 99 598 adults (40 071 men and 59 527 women). Setting: The survey was carried out in the city of Mumbai (formerly known as Bombay) in western India. Participants: Men and women aged >35 years who were residents of the main city of …

Aha/Acc Guidelines For Preventing Heart Attack And Death In Patients With Atherosclerotic Cardiovascular Disease: 2001 Update - A Statement For Healthcare Professionals From The American Heart Association And The American College Of Cardiology, Sidney C. Smith Jr., Steven N. Blair, Robert O. Bonow, Lawrence M. Brass, Manuel D. Cerqueira, Kathleen Dracup, Valentin Fuster, Antonio M. Gotto, Scott M. Grundy, Nancy Houston-Miller, Alice Jacobs, Daniel Jones, Ronald M. Krauss, Lori Mosca, Ira S. Ockene, Richard C. Pasternak, Thomas A. Pearson, Marc A. Pfeffer, Rodman K. Starke, Kathryn A. Taubert

Faculty Publications

No abstract provided.

Proteolytic Enzymes In The Marine Bacterium Pseudoalteromonas Atlantica: Post-Secretional Activation And Effects Of Environmental Conditions, Monica Hoffman, Alan W. Decho

Faculty Publications

Production and activities of cellular and extracellular proteolytic enzymes associated with the marine bacterium Pseudoalteromonas atlantica were examined in response to physiological state and changing environmental variables under laboratory conditions. Enzymes evidenced by zymography were metalloproteases, as defined by substrate preference and susceptibility to inhibitors (EDTA and 1, 10-phenanthroline). Distinct bands (i.e. molecular-weight [MW] size classes) of enzymes were isolated from within cellular and extracellular compartments. Susceptibility of extracellular enzymes to environmental stressors was related, in part, to the MW size classes of the enzymes. While all bands of enzymes showed some degree of inhibition when pH was decreased, the …

Biomedical Research Leaders: Report On Needs, Opportunities, Difficulties, Education And Training, And Evaluation, Samuel H. Wilson, Deborah Brown, Jay Moskowitz, Dan Hurley, David Brown, David Brown, Byron J. Bailey, Michael Mcclain, Marilyn Misenhimer, Judith Buckalew, Thomas Burks

Faculty Publications

The National Association of Physicians for the Environment (NAPE) has assumed a leadership role in protecting environmental health in recent years. The Committee of Biomedical Research Leaders was convened at the recent NAPE Leadership Conference: Biomedical Research and the Environment held on 1–2 November 1999, at the National Institutes of Health, Bethesda, Maryland. This report summarizes the discussion of the committee and its recommendations. The charge to the committee was to raise and address issues that will promote and sustain environmental health, safety, and energy efficiency within the biomedical community. Leaders from every important research sector (industry laboratories, academic health …

The Use Of Uniaxial And Triaxial Accelerometers To Measure Children's "Free-Play" Physical Activity, Alise E. Ott, Russell R. Pate, Stewart G. Trost, Dianne S. Ward, Ruth P. Saunders

Faculty Publications

In order to effectively measure the physical activity of children, objective monitoring devices must be able to quantify the intermittent and nonlinear movement of free play. The purpose of this study was to investigate the validity of the Computer Science and Applications (CSA) uniaxial accelerometer and the TriTrac-R3D triaxial accelerometer with respect to their ability to measure 8 "free-play" activities of different intensity. The activities ranged from light to very vigorous in intensity and included activities such as throwing and catching, hopscotch, and basketball. Twenty-eight children, ages 9 to 11, wore a CSA and a heart rate monitor while performing …

Children's Understanding Of The Concept Of Physical Activity, Stewart G. Trost, Angela M. Morgan, Ruth P. Saunders, Gwen A. Felton, Dianne S. Ward, Russell R. Pate

Faculty Publications

This study evaluated 4th-grade students' understanding of the concept of physical activity and assessed the effects of two interventions to enhance the students' understanding of this concept. Students were randomly assigned to 1 of 3 conditions: the video group (n=40) watched a 5-min video describing physical activity; the verbal group (n=42) listened to a generic description of physical activity; the control group received no instruction (n=45). Students completed a 17-item checklist testing their understanding of the concept of physical activity. Compared to controls, students in the verbal and video group demonstrated significantly higher checklist …

Comparison Of A Dietary Record Using Reported Portion Size Versus Standard Portion Size For Assessing Nutrient Intake, Desiree C. Welten, Ruth A. Carpenter, R. Sue Mcpherson, Suzanne Brodney, Deirdre Douglass, James B. Kampert, Steven N. Blair

Faculty Publications

Objective: Because the percentage of missing portion sizes was large in the Aerobics Center Longitudinal Study (ACLS), careful consideration of the accuracy of standard portion sizes was necessary. The purpose of the present study was to investigate the consequences of using standard portion size instead of reported portion sizes on subjects' nutrient intake.

Methods: In 2307 men and 411 women, nutrient intake calculated from a 3-day dietary record using reported portion sizes was compared with nutrient intake calculated from the same record in which standard portion sizes were substituted for reported portion sizes.

Results: The standard portion sizes provided significantly …