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Articles 361 - 390 of 417
Full-Text Articles in Public Health
Gender Difference In Traumatic Brain Injury Outcomes: Survival, Functional Independence, And Employment Status, Andrea T. Underhill
Gender Difference In Traumatic Brain Injury Outcomes: Survival, Functional Independence, And Employment Status, Andrea T. Underhill
All ETDs from UAB
Medical and rehabilitative care of women living with traumatic brain injury (TBI) is based on information drawn from research conducted primarily on men. Care for men may be adequate for women, but all of the body’s organs have the capability to respond differently based on gender, and research should examine the genders separately. This dissertation examines the survival to 24 months post-TBI and the functional independence and employment status at 12 and 24 months post-TBI of men and women. Participants were drawn from a longitudinal study of injured persons and include those diagnosed only with a TBI. Variables used in …
Partner Referral Among Patients With Sexually Transmitted Diseases In Dhaka, Bangladesh, Nazmul Alam
Partner Referral Among Patients With Sexually Transmitted Diseases In Dhaka, Bangladesh, Nazmul Alam
All ETDs from UAB
This dissertation puts together three closely related articles on partner referral for sexually transmitted diseases (STD). The first paper sought to understand feasibility and acceptability of partner referral for STD in less developed countries using a systematic literature review. The results summarized from 39 articles indicate that partner referral outcome was more common for spousal partners than for causal partners. Client's reported barriers included stigma and fear of abuse while infrastructural barriers included limited resources are important. Client centered counseling was found to be effective in increasing partner referral in Africa. The second paper aimed to determine if intention of …
Diagnosing Antiretroviral Treatment Failure In Resource-Limited Settings, Ronald Alexander Cantrell
Diagnosing Antiretroviral Treatment Failure In Resource-Limited Settings, Ronald Alexander Cantrell
All ETDs from UAB
This dissertation had three central goals. The first was to review the existing literature for reports of virologic failure among adults initiating non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in resource-limited settings. The second was to describe the epidemiology of virologic failure over the first 6 months of therapy in Lusaka, Zambia. The third was to examine the performance of different approaches for diagnosing virologic failure. We performed a meta-analysis using data from previously published reports to create summary estimates for the prevalence of virologic failure and found that the lowest estimate of the 95% confidence interval was 10% or higher …
Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones
Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones
All ETDs from UAB
Mutations to copper,zinc superoxide dismutase (Cu,Zn SOD or SOD1) are the only known causes of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized primarily by death of spinal motor neurons. While the molecular mechanisms responsible for motor neuron death in this disease remain to be elucidated, recent studies implicate mitochondrial dysfunction as a key factor in the pathogenesis of ALS. In support of this, we observed ALS-dependent alterations in key functions including creatine kinase activity and ATP levels, which could be linked to changes in the mitochondrial proteome. Importantly, extensive research efforts have failed to develop a treatment that significantly …
Evaluation Of Pre And Post Treatment Filtration Performance Of Kinetico Macrolite® Ceramic Media Compared To Traditional Sand/Anthracite And Gac Filters In Drinking Water Treatment Process, Jeff Cochran
All ETDs from UAB
This study was conducted in conjunction with the Birmingham Water Works Board to evaluate Kinetico ceramic filter media against GAC (Granular Activated Carbon) and Sand/Anthracite filters. The Birmingham Water Works Board Water Treatment Pilot Plant was located and operated on the Shades Mountain Filter Plant (SMFP) premises. The evaluation was conducted in three phases: plant matching, plant optimization, and pre-filter testing. The initial phase called for determining the best combination of Kinetico Macrolite Ceramic media to match or outperform the existing Sand/Anthracite dual media filters located at SMFP. At the end of the testing it was determined that 18 inches …
The Relationship Of Medical Homeness To The Quality Of Life Of Mothers Of Children With And Without Special Health Care Needs, Cynthia G. Cortes
The Relationship Of Medical Homeness To The Quality Of Life Of Mothers Of Children With And Without Special Health Care Needs, Cynthia G. Cortes
All ETDs from UAB
A cross-sectional study was conducted to investigate the relationship of child, family, and medical home status to quality of life for mothers of children with and without special health care needs. Mothers of children with (n=100) and without (n=80) special health care needs, completed a questionnaire at a children’s hospital in the southeastern United States focusing on the child, family, and medical home and maternal quality of life. Standardized instruments were used to measure quality of life (SF-36) and social support (Social Support Questionnaire). Non-standardized instruments used in other research were incorporated into the maternal questionnaire. Logistic and linear regression …
Interim Monitoring Efficacy, Safety And Futility In Phase Iii Clinical Trials, Qing Li
Interim Monitoring Efficacy, Safety And Futility In Phase Iii Clinical Trials, Qing Li
All ETDs from UAB
Phase III trials often have both efficacy and safety outcomes. Sometimes the safety outcomes are closely associated with the efficacy outcomes. We sought to find a statistical method to treat both efficacy and safety outcomes as bivariate primary outcomes and set up stopping rules at interim stages based on the following criteria: (1) greater safety; (2) greater efficacy; (3) futility. We first examined the internal pilot design to adjust sample size for clinical trials with a bivariate response (efficacy and safety). Three nuisance parameters (two variances and correlation) need to be considered when doing sample size recalculation for the internal …
Air Pollution And Preterm Births In Atlanta, Georgia, Corey Masuca
Air Pollution And Preterm Births In Atlanta, Georgia, Corey Masuca
All ETDs from UAB
Exposure to ambient outdoor air pollution exposure is one of the many extraneous factors associated with preterm births. Many epidemiological studies involving preterm births and ambient air pollution have repeatedly indicated positive associations. However, for many such studies, results may be statistically significant but weakly associated or inconclusive. Such results may be primarily attributable to the fact that most studies include only single or multiple criteria air pollutants but not the total air pollution mixture of criteria air pollutants and air toxic pollutants (e.g., PAHs) to which people are actually exposed. This study assessed associations between pollutant classes, including criteria …
Randomized Controlled Trial Of Low Cost Interventions To Reduce Childhood Immunization Dropouts In Pakistan, Hussain Raza Usman
Randomized Controlled Trial Of Low Cost Interventions To Reduce Childhood Immunization Dropouts In Pakistan, Hussain Raza Usman
All ETDs from UAB
Childhood immunization coverage in Pakistan remains sub-optimal despite universal and free of cost availability of vaccines. Structural impediments to progress may include the immunization card that is hard to read and interpret. A randomized controlled trial was conducted to assess the effect of redesigned immunization card and center-based education to mothers on immunization completion at rural immunization centers in Karachi, Pakistan. Other objectives were to identify the predictors of immunization completion and to identify factors associated with delay at first dose of diphtheria-tetanuspertussis (DTP1). Mother-child units were enrolled from six immunization centers at DTP1 and randomized to four study groups: …
The Effect Of Malaria And Intestinal Helminth Coinfection On Birth Outcomes In Ghana, Nelly J. Yatich
The Effect Of Malaria And Intestinal Helminth Coinfection On Birth Outcomes In Ghana, Nelly J. Yatich
All ETDs from UAB
Several studies have reported the relationship between malaria during pregnancy and adverse pregnancy outcomes including maternal anemia, low birthweight, as well as preterm delivery and small for gestational age infants. Some studies have also demonstrated the linkage between helminth infection and maternal anemia. Few studies have assessed the occurrence of coinfection of these infections in pregnancy and its effects on maternal anemia and birth outcomes. The objective of this dissertation was to assess the effect of malaria and intestinal helminth coinfection on birth outcomes in Ghana. A cross-sectional study of 785 women presenting for delivery in two hospitals in Kumasi, …
Wavelet-Based Regression And Classification For Longitudinal Diffusion Tensor Imaging Data, William R. Prucka
Wavelet-Based Regression And Classification For Longitudinal Diffusion Tensor Imaging Data, William R. Prucka
All ETDs from UAB
Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique capable of in vivo characterization of the spatial and angular dependence of free water diffusion in tissue. By studying intra- and extra-cellular water mobility, inference can be made about the surrounding medium. The non-uniform angular dependence of diffusion, known as anisotropy, is evident in fibrous tissues, which exhibit greater diffusion parallel versus perpendicular to the fiber orientation. DTI’s sensitivity to anisotropy makes it an effective tool for measuring the integrity of fibrous myelinated white matter tracts in the brain. For demyelinating diseases such as multiple sclerosis (MS), DTI has …
Predictors Of Indoor Dust Mite And Cockroach Levels, J Mark Brooks
Predictors Of Indoor Dust Mite And Cockroach Levels, J Mark Brooks
All ETDs from UAB
Exposures to dust mite and cockroach indoor allergens are important environmental risk factors in allergic sensitization and the development and exacerbation of asthma. To determine the relationship of indoor allergen levels and residence characteristics, dust samples were collected from indoor surfaces in residences in the Birmingham, Alabama area. The dust samples were analyzed for specific dust mite (Der p 1 and Der f 1) and cockroach (Bla g 1) antigens, the results of which were used to represent the level of indoor allergen present in each residence. The presence, and in some cases the degree, of potential allergen-predicting characteristics of …
Factors Associated With Sexual Debut And Depression Among Adolescents In Rural Jamaica, Olaniyi J. Ekundayo
Factors Associated With Sexual Debut And Depression Among Adolescents In Rural Jamaica, Olaniyi J. Ekundayo
All ETDs from UAB
Individual and family factors have been hypothesized to influence adolescent sexual behavior and depression, but the extent to which this is true for adolescents in Jamaica as a whole and for those in rural areas in particular, has not been well studied. The objective of this dissertation was to identify individual and family factors associated with sexual debut and depression among rural Jamaican adolescents. To elucidate these factors and to provide information to guide future interventions, we analyzed data on 748 adolescents attending public high schools in the rural parish of Hanover, Jamaica. Multivariate logistic regression was used to predict …
Sexual Violence And Correlates Among Women In Hiv Discordant Union, Uganda, Donath Emusu
Sexual Violence And Correlates Among Women In Hiv Discordant Union, Uganda, Donath Emusu
All ETDs from UAB
We sought to estimate the prevalence of sexual violence and sexually transmitted diseases (STDs), identify risk factors for sexual violence and STDs among women in Human Immunodeficiency Virus (HIV) discordant unions, and investigate the lived experiences of sexual violence among women in HIV discordant unions attending post-test club services at AIDS Information Centers (AICs) in Uganda. We carried out a prospective cohort study of women in HIV discordant and HIV negative concordant unions after disclosure of their HIV serostatus. We estimated prevalence of STDs in the two study cohorts and compared them for occurrence of risk factors for sexual violence …
Titania Coated Hollow Glass Microspheres For Environmental Applications, Mark C. Koopman
Titania Coated Hollow Glass Microspheres For Environmental Applications, Mark C. Koopman
All ETDs from UAB
The potential applicability of titania coated hollow glass microspheres (HGMs) to the photocatalytic degradation of microbiological and organic chemical water pollutants could have dramatic positive effects on improving the quality of industrial wastewaters that empty into rivers and streams, as well as potential use in economically improving the quality of drinking water. Heterogeneous photocatalysis using titania has been extensively studied since the 1990’s because of its non-toxic nature, its high quantum yield of electrons and photo-holes, and its ability to use ambient solar radiation as a power source. Although titania embodies extraordinarily attractive properties for a range of environmental applications, …
Delayed Childbearing, Pregnancy Spacing And Impact On Subsequent Pregnancy Outcomes: Missouri Resident Mothers 1978-1997, Sarah K. Nabukera
Delayed Childbearing, Pregnancy Spacing And Impact On Subsequent Pregnancy Outcomes: Missouri Resident Mothers 1978-1997, Sarah K. Nabukera
All ETDs from UAB
Introduction The main objective of the study was to examine reproductive health issues among women delaying initiation of childbearing until age 30 or older. Specifically, it examined pregnancy spacing patterns, relationship between pregnancy spacing and subsequent perinatal outcomes as well as racial differences in spacing and adverse perinatal outcomes. Methods A retrospective cohort study was conducted using the Missouri maternally linked live birth, fetal death and infant death files 1978-1997. The study sample was limited to mothers residing in Missouri during the study period, having first pregnancy at age 20-50 years, as well as a subsequent second pregnancy. Final study …
Association Between The Exposure To Aflatoxin And Micronutrient Status Of Hiv Infected Adults In Ghana, Francis Ayodele Obuseh
Association Between The Exposure To Aflatoxin And Micronutrient Status Of Hiv Infected Adults In Ghana, Francis Ayodele Obuseh
All ETDs from UAB
Aflatoxins, found naturally in some foods are toxic metabolites of some Aspergillus species.They constitute the most potent hepatocarcinogens known and are also mutagenic and hepatotoxic. The preponderance of evidence indicates that aflatoxin is the major cause of hepatocellular cancer. In studies conducted in Africa, food-borne aflatoxin exposure is common (Oyelami et al. 1996; Egal et al. 2005). There is a critical need for additional information on health outcomes associated with exposure to aflatoxin in humans, especially in developing countries with a higher degree of malnutrition and likelihood of HIV infections. We sought to test the hypothesis that aflatoxin B1 and …
Caste As A Determinant Of Utilization Of Maternal And Neonatal Healthcare Services In Maitha, Uttar Pradesh, India, Ekta Saroha
Caste As A Determinant Of Utilization Of Maternal And Neonatal Healthcare Services In Maitha, Uttar Pradesh, India, Ekta Saroha
All ETDs from UAB
Caste among Hindus in India is a non-modifiable socio-demographic characteristic, often the basis of segregation and discrimination. Despite the provision of subsidized maternal and child healthcare services, utilization in rural Uttar Pradesh (UP), India is poor. Studies showed that upper caste (UC) women were more likely to utilize healthcare services than the lower caste (LC) women but this association is inadequately researched. We explored whether caste was a determinant of utilization of maternal healthcare (MH) and neonatal healthcare (NH) services among rural Hindu women and neonates in Maitha, UP, India. Data from the ‘Morbidity and Performance Assessment’ study for 482 …
Examination Of Novel Statistical Designs For Phase Ii And Phase Iii Clinical Trials, Ayanbola Olajumoke Ayanlowo
Examination Of Novel Statistical Designs For Phase Ii And Phase Iii Clinical Trials, Ayanbola Olajumoke Ayanlowo
All ETDs from UAB
Clinical trials to determine the usefulness of a new treatment are usually conducted in four (4) phases. Each phase is designed to answer a distinct research question about the usefulness of the new treatment. Phase I trials determine the safe dose range of the new treatment identify the possible side effects and other treatment associated toxicity issues, in a small group of healthy people. In phase II trials, the efficacy and safety of the new treatment is investigated in a larger group of individuals usually from the diseased population of interest. Phase III trials, conducted in large groups of people, …
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
All ETDs from UAB
Persistent infection with certain “high-risk” types of human papillomavirus (HPV) infection is central to the development of cervical cancer. Human immunodeficiency virus (HIV)-infected women are at a higher risk of HPV infection, high grade cervical intraepithelial lesions, and cervical cancer. This study examined type-specific distribution of prevalent and incident HPV infections, clearance rates, and associated factors using novel molecular assays for HPV detection and genotyping in a cohort of 280 HIVinfected women in Alabama. First, we described the cohort’s sociodemographic characteristics and behavioral risk profile for HIV and other sexually transmitted infections, and assessed the factors associated with HIV-1 viral …
Cervical Cancer Screening For Hiv-Infected Women In Zambia., Vikrant Sahasrabuddhe
Cervical Cancer Screening For Hiv-Infected Women In Zambia., Vikrant Sahasrabuddhe
All ETDs from UAB
No abstract provided.
Factors For Hiv /Aids Risk In Yunnan Province, China Near The Myanmar Border., Yan Xiao
Factors For Hiv /Aids Risk In Yunnan Province, China Near The Myanmar Border., Yan Xiao
All ETDs from UAB
No abstract provided.
Contribution Of Non-Occupational Exposure Factors And Non-Noise Occupational Exposure To Loss Of Hearing Sensitivity Among Anniston Army Depot Worker., Katrina L. Wright
Contribution Of Non-Occupational Exposure Factors And Non-Noise Occupational Exposure To Loss Of Hearing Sensitivity Among Anniston Army Depot Worker., Katrina L. Wright
All ETDs from UAB
No abstract provided.
The Determinants Of Medicaid Participation Among Private Primary Care Dentists In Alabama., Dania E. Al Agili
The Determinants Of Medicaid Participation Among Private Primary Care Dentists In Alabama., Dania E. Al Agili
All ETDs from UAB
No abstract provided.
Small For Gestational Age Infants: Survival And Impact Of Advanced Maternal Age., Sibylle Kristensen
Small For Gestational Age Infants: Survival And Impact Of Advanced Maternal Age., Sibylle Kristensen
All ETDs from UAB
No abstract provided.
A Geographic Study Of Childhood Cancers Near Hazardous Waste Sites In Florida., Gregory D. Kearney
A Geographic Study Of Childhood Cancers Near Hazardous Waste Sites In Florida., Gregory D. Kearney
All ETDs from UAB
No abstract provided.
Intimate Partner Violence Among Low -Income Pregnant Women: Multi-Level Analysis., Qing Li
Intimate Partner Violence Among Low -Income Pregnant Women: Multi-Level Analysis., Qing Li
All ETDs from UAB
No abstract provided.
Antenatal Syphilis Management In Sub -Saharan Africa: Public Health Management Challenges And The Impact Of New Hiv Programs In Zambia., Dara G. Potter
Antenatal Syphilis Management In Sub -Saharan Africa: Public Health Management Challenges And The Impact Of New Hiv Programs In Zambia., Dara G. Potter
All ETDs from UAB
No abstract provided.
Pediatric Iron Toxicity: The Impact Of Unit Dose Packaging., Ann P. Slattery
Pediatric Iron Toxicity: The Impact Of Unit Dose Packaging., Ann P. Slattery
All ETDs from UAB
No abstract provided.
The Relationship Between Hyperfertility (Parity≥15) And Fetal Outcomes Among Singleton Births., Muktar H. Aliyu
The Relationship Between Hyperfertility (Parity≥15) And Fetal Outcomes Among Singleton Births., Muktar H. Aliyu
All ETDs from UAB
No abstract provided.