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Full-Text Articles in Public Health

Neurodevelopment Correlates With Gut Microbiota In A Cross-Sectional Analysis Of Children At 3 Years Of Age In Rural China, Sarah E. Rothenberg, Qiurong Chen, Yanfen Nong, Hua Nong, Eva P. Trinh, Fred J. Biasini, Jihong Liu, Xiaoyun Zeng, Yunfeng Zou, Fengxiu Ouyang, Susan A. Korrick Apr 2021

Neurodevelopment Correlates With Gut Microbiota In A Cross-Sectional Analysis Of Children At 3 Years Of Age In Rural China, Sarah E. Rothenberg, Qiurong Chen, Yanfen Nong, Hua Nong, Eva P. Trinh, Fred J. Biasini, Jihong Liu, Xiaoyun Zeng, Yunfeng Zou, Fengxiu Ouyang, Susan A. Korrick

Faculty Publications

We investigated cross-sectional associations between children’s neurodevelopment and their gut microbiota composition. Study children (36 months of age) lived in rural China (n = 46). Neurodevelopment was assessed using the Bayley Scales of Infant Development, 2nd Edition, yielding the Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI). Children's gut microbiota was assessed using 16S rRNA gene profiling. Microbial diversity was characterized using alpha diversity patterns. Additionally, 3 coabundance factors were determined for the 25 most abundant taxa. Multivariable linear regression models were constructed to examine the relationships between Bayley scores (MDI and PDI) and children's gut microbiota. In adjusted …


The Pharmaceutical Industry Contributes To Public Health, Karl E. Peace, Mario Keko Apr 2021

The Pharmaceutical Industry Contributes To Public Health, Karl E. Peace, Mario Keko

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

No abstract provided.


Socastee Interview, Participant #08, March 31, 2021, Jennifer Mokos, Jaime Mccauley Mar 2021

Socastee Interview, Participant #08, March 31, 2021, Jennifer Mokos, Jaime Mccauley

Flood Survivor Interviews

A community member of the Rosewood neighborhood in Socastee is interviewed by a CCU student.


Socastee Interview, Participant #04, March 30, 2021, Jennifer Mokos, Jaime Mccauley Mar 2021

Socastee Interview, Participant #04, March 30, 2021, Jennifer Mokos, Jaime Mccauley

Flood Survivor Interviews

A community member of the Rosewood neighborhood in Socastee is interviewed by a CCU student.


Socastee Interview, Participant #03, March 26, 2021, Jennifer Mokos, Jaime Mccauley Mar 2021

Socastee Interview, Participant #03, March 26, 2021, Jennifer Mokos, Jaime Mccauley

Flood Survivor Interviews

A community member of the Rosewood neighborhood in Socastee is interviewed by a CCU student.


Socastee Interview, Participant #01, March 26, 2021, Jennifer Mokos, Jaime Mccauley Mar 2021

Socastee Interview, Participant #01, March 26, 2021, Jennifer Mokos, Jaime Mccauley

Flood Survivor Interviews

A community member of the Rosewood neighborhood in Socastee is interviewed by CCU students.


Sars-Cov-2 Transmission In Alberta, British Columbia, And Ontario, Canada, December 25, 2019, To December 1, 2020, Isaac Chun-Hai Fung, Yuen Wai Hung, Sylvia Ofori, Kamalich Muniz-Rodriguez, Po-Ying Lai, Gerardo Chowell Mar 2021

Sars-Cov-2 Transmission In Alberta, British Columbia, And Ontario, Canada, December 25, 2019, To December 1, 2020, Isaac Chun-Hai Fung, Yuen Wai Hung, Sylvia Ofori, Kamalich Muniz-Rodriguez, Po-Ying Lai, Gerardo Chowell

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

Objective:

This study aimed to investigate coronavirus disease (COVID-19) epidemiology in Alberta, British Columbia, and Ontario, Canada.

Methods:

Using data through December 1, 2020, we estimated time-varying reproduction number, R t , using EpiEstim package in R, and calculated incidence rate ratios (IRR) across the 3 provinces.

Results:

In Ontario, 76% (92 745/121 745) of cases were in Toronto, Peel, York, Ottawa, and Durham; in Alberta, 82% (49 878/61 169) in Calgary and Edmonton; in British Columbia, 90% (31 142/34 699) in Fraser and Vancouver Coastal. Across 3 provinces, R t dropped to ≤ 1 after April. …


Characterization, Bio-Uptake And Toxicity Of Polymer-Coated Silver Nanoparticles And Their Interaction With Human Peripheral Blood Mononuclear Cells, Sahar Pourhoseini, Reilly T. Enos, Angela E. Murphy, Bo Cai Ph.D., Jamie Lead Mar 2021

Characterization, Bio-Uptake And Toxicity Of Polymer-Coated Silver Nanoparticles And Their Interaction With Human Peripheral Blood Mononuclear Cells, Sahar Pourhoseini, Reilly T. Enos, Angela E. Murphy, Bo Cai Ph.D., Jamie Lead

Faculty Publications

Silver nanoparticles (AgNPs) are widely used in medical applications due to their antibacterial and antiviral properties. Despite the extensive study of AgNPs, their toxicity and their effect on human health is poorly understood, as a result of issues such as poor control of NP properties and lack of proper characterization. The aim of this study was to investigate the combined characterization, bio-uptake, and toxicity of well-characterized polyvinylpyrrolidone (PVP)-coated AgNPs in exposure media during exposure time using primary human cells (peripheral blood mononuclear cells (PBMCs)). AgNPs were synthesized in-house and characterized using a multimethod approach. Results indicated the transformation of NPs …


Comparison Of The Effectiveness Of Disinfectant-Impregnated Wipes Versus Detergent Wipes For Surface Decontamination, Jacob Amadin Mar 2021

Comparison Of The Effectiveness Of Disinfectant-Impregnated Wipes Versus Detergent Wipes For Surface Decontamination, Jacob Amadin

USF Tampa Graduate Theses and Dissertations

Over time, there is an increased need to adopt more advanced and effective ways of disinfection. The emergence of the coronavirus-2019 (COVID-19) pandemic reminded the world on the importance of disinfection. Disinfection has been a routine in the healthcare setting. However, with the current pandemic problem, it is more prominently and persistently done in the domestic setting and other business settings beyond healthcare. As such, the use of most disinfectants and detergent wipes to achieve a near sanitized environment has become a common practice around the globe. This research presents the efficacy of disinfectant impregnated versus detergents wipes through comparison. …


Relationship Between Diet Quality Scores And The Risk Of Frailty And Mortality In Adults Across A Wide Age Spectrum, Kulapong Jayanama, Olga Theou, Judith Godin, Leah Cahill, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert, Michael David Wirth Msph, Phd, Yong-Moon Park, Teresa T. Fung, Kenneth Rockwood Mar 2021

Relationship Between Diet Quality Scores And The Risk Of Frailty And Mortality In Adults Across A Wide Age Spectrum, Kulapong Jayanama, Olga Theou, Judith Godin, Leah Cahill, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert, Michael David Wirth Msph, Phd, Yong-Moon Park, Teresa T. Fung, Kenneth Rockwood

Faculty Publications

Background

Beyond intakes of total energy and individual nutrient, eating patterns may influence health, and thereby the risk of adverse outcomes. How different diet measures relate to frailty—a general measure of increased vulnerability to unfavorable health outcomes—and mortality risk, and how this might vary across the life course, is not known. We investigated the associations of five dietary indices (Nutrition Index (NI), the energy-density Dietary Inflammatory Index (E-DII™), Healthy Eating Index-2015 (HEI-2015), Mediterranean Diet Score (MDS), and Dietary Approaches to Stop Hypertension (DASH)) with frailty and mortality.

Methods

We included 15,249 participants aged ≥ 20 years from the 2007–2012 cohorts …


Using A Hybrid Agent-Based And Equation Based Model To Test School Closure Policies During A Measles Outbreak, Elizabeth Hunter, John D. Kelleher Mar 2021

Using A Hybrid Agent-Based And Equation Based Model To Test School Closure Policies During A Measles Outbreak, Elizabeth Hunter, John D. Kelleher

Articles

Background

In order to be prepared for an infectious disease outbreak it is important to know what interventions will or will not have an impact on reducing the outbreak. While some interventions might have a greater effect in mitigating an outbreak, others might only have a minor effect but all interventions will have a cost in implementation. Estimating the effectiveness of an intervention can be done using computational modelling. In particular, comparing the results of model runs with an intervention in place to control runs where no interventions were used can help to determine what interventions will have the greatest …


Lag Effects Of Ozone, Pm2.5, And Meteorological Factors On Covid-19 New Cases At The Disease Epicenter In Queens, New York, Atin Adhikari, Jingjing Yin Mar 2021

Lag Effects Of Ozone, Pm2.5, And Meteorological Factors On Covid-19 New Cases At The Disease Epicenter In Queens, New York, Atin Adhikari, Jingjing Yin

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

The influences of environmental factors on COVID-19 may not be immediate and could be lagged for days to weeks. This study investigated the choice of lag days for calculating cumulative lag effects of ozone, PM2.5, and five meteorological factors (wind speed, temperature, relative humidity, absolute humidity, and cloud percentages) on COVID-19 new cases at the epicenter of Queens County, New York, before the governor’s executive order on wearing of masks in public places (1 March to 11 April 2020). Daily data for selected air pollutants and meteorological factors were collected from the US EPA Air Quality System, weather observation station …


Validation Of Icd-10-Cm Codes For Injuries Complicating Pregnancy, Childbirth And The Puerperium: A Medical Record Review, Anna Hansen, Dana Quesinberry, Peter Akpunonu, Julia Martin, Svetla Slavova Mar 2021

Validation Of Icd-10-Cm Codes For Injuries Complicating Pregnancy, Childbirth And The Puerperium: A Medical Record Review, Anna Hansen, Dana Quesinberry, Peter Akpunonu, Julia Martin, Svetla Slavova

Kentucky Injury Prevention and Research Center Faculty Publications

INTRODUCTION: The purpose of this study was to estimate the positive predictive value (PPV) of International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes for injury, poisoning, physical or sexual assault complicating pregnancy, childbirth and the puerperium (PCP) to capture injury encounters within both hospital and emergency department claims data.

METHODS: A medical record review was conducted on a sample (n=157) of inpatient and emergency department claims from one Kentucky healthcare system from 2015 to 2017, with any diagnosis in the ICD-10-CM range O9A.2-O9A.4. Study clinicians reviewed medical records for the sampled cases and used an abstraction form to …


Healthy Trees – Healthy People: A Model For Engaging Citizen Scientists In Exotic Pest Detection In Urban Parks, Heather Norman-Burgdolf, Lynne K. Rieske Mar 2021

Healthy Trees – Healthy People: A Model For Engaging Citizen Scientists In Exotic Pest Detection In Urban Parks, Heather Norman-Burgdolf, Lynne K. Rieske

Dietetics and Human Nutrition Faculty Publications

Healthy Trees – Healthy People (HT-HP) is an outreach and education program created to enlist and train participants in exotic pest detection while providing them with structured opportunities to connect with urban nature and increase their physical and emotional health. HT- HP creates infrastructure to increase engagement by the urban populace in the urban tree canopy. The program solicits participants to engage in an 8-week intervention designed to expand capacity to detect non-native insect pests and pathogens, while increasing physical activity, raising awareness of healthy lifestyle choices, and improving the health of participants. Program participants were trained in tree and …


Predictive Modeling And Estimation Of The Doubling Time Of Confirmed Cases Of Covid-19 In Niger, Ibrahim Sidi Zakari, Hadiza Galadima Mar 2021

Predictive Modeling And Estimation Of The Doubling Time Of Confirmed Cases Of Covid-19 In Niger, Ibrahim Sidi Zakari, Hadiza Galadima

Community & Environmental Health Faculty Publications

Modeling is increasingly used to assess scenarios and make projections on the future course of new coronavirus disease. This allows for better planning of care as well as a relaxation or tightening of the restrictive measures decreed by the government and the health authorities. The data analyzed in this study covers the period from March 19 to June 05, 2020 and allowed predictions of new cases of COVID-19 based on a growth model with a growth rate that changes linearly over time. In addition, we calculated and predicted the doubling time of the number of positive cases in each region …


Analyzing Student Experience On Group Work With The Application Of Different Group Allocation Approaches, An Yee Tan Mar 2021

Analyzing Student Experience On Group Work With The Application Of Different Group Allocation Approaches, An Yee Tan

Management and HR

Working as a group can be as challenging as working by oneself. Common issues like ineffective group work, unequal work contribution, and poor communication are believed to be the reasons why many students preferred to work individually. The purpose of this study is to understand if there is a disparity in student experience on group work by implementing different methods of group formation, which are, intentional group formation and random assignment. Topics around team well-being, team communication, and team effectiveness are the main focus of this study. The second emphasis of this study is students’ opinions on whether or not …


Exclusive Breastfeeding History Risk Factor Associated With Stunting Of Children Aged 12–23 Months, Nurhalina Sari, Marlida Yuliza Manjorang, Zakiyah Zakiyah, Madeleine Randell Feb 2021

Exclusive Breastfeeding History Risk Factor Associated With Stunting Of Children Aged 12–23 Months, Nurhalina Sari, Marlida Yuliza Manjorang, Zakiyah Zakiyah, Madeleine Randell

Kesmas

Stunting (low height-for-age) remains a global and national health problem because it increases the risk of disturbances in growth and development and mortality. Banjar Margo District, Tulang Bawang Regency, has the second-highest prevalence in Lampung Province, Indonesia. This study aimed to analyze the association of exclusive breastfeeding history and stunting in children aged 12–23 months in Banjar Margo District. This study used a cross-sectional design on 193 children aged 12–23 months. It was primary data conducted between April and May 2018 with a questionnaire. Data analysis was performed using the chi-square test and multiple logistic regression. The result showed that …


Junk Food Consumption And Symptoms Of Mental Health Problems: A Meta-Analysis For Public Health Awareness, Muhammad Hafizurrachman, Risky Kusuma Hartono Feb 2021

Junk Food Consumption And Symptoms Of Mental Health Problems: A Meta-Analysis For Public Health Awareness, Muhammad Hafizurrachman, Risky Kusuma Hartono

Kesmas

Junk food consumption increases the risk of having symptoms of mental health problems. This study aimed to conduct a meta-analysis to assess the association between junk food and symptoms of mental health problems. Six researchers, two primary researchers, and four assistant researchers, from October to December 2020 conducted a systematic literature review. The data sources were selected from Pubmed and Science Direct articles published from 2010 to 2020. Those websites were check-marked for text availability for original articles, using keywords for junk foods and mental health. This study had inclusion criteria for selecting and organizing articles using the Preferred Reporting …


Assessment Of Characteristics And Conditions Before The End Of Lockdown, David San-Martín-Roldán, Francisca Rojo-Lazo, Aracelis Calzadilla-Núñez, Pablo San-Martín-Roldán, Patricia Díaz-Calzadilla, Víctor P. Díaz-Narváez Feb 2021

Assessment Of Characteristics And Conditions Before The End Of Lockdown, David San-Martín-Roldán, Francisca Rojo-Lazo, Aracelis Calzadilla-Núñez, Pablo San-Martín-Roldán, Patricia Díaz-Calzadilla, Víctor P. Díaz-Narváez

Kesmas

After months of blockades and restriction, the decision of the best time to end the lockdown after the first wave of the COVID-19 pandemic is the big question for health rectors. This study aimed to evaluate the characteristics and conditions for ending the blockade after the first wave of COVID-19. Data on the variables of interest were subjected to linear and non-linear regression studies to determine the curve that best explains the data. The coefficient of determination, the standard deviation of y in x, and the observed curve of the confidence interval were estimated. Regression which was estimated subsequently revealed …


Analysis Of Measles Vaccination Refusal On Social Media (Facebook) Among Anti-Vaccine Communities In Indonesia, Dwi Meilani, Evi Martha, Hadi Pratomo, Indah Jamiatun Hasanah, Somporn Rungreangkulkij Feb 2021

Analysis Of Measles Vaccination Refusal On Social Media (Facebook) Among Anti-Vaccine Communities In Indonesia, Dwi Meilani, Evi Martha, Hadi Pratomo, Indah Jamiatun Hasanah, Somporn Rungreangkulkij

Kesmas

Measles is one of the main causes of global mortality in the under-fives. The existence of groups that reject immunization caused a decrease in immunization coverage. Anti-vaccine messages are widely delivered on social media. Identification of vaccine rejection behavior can be used as the basis to formulate effective program strategies. The design of this study used rapid assessment procedures (RAP). The informants were from two anti-vaccine communities in the Facebook group. In-depth interviews and observations were done for data collection, and data analysis was performed using the Framework Method. The results found that determinants, such as knowledge, beliefs in health …


Parity And Marital Status As Factors Influencing Contraceptive Use Among Adolescents In Indonesia, Anni Fithriyatul Mas'udah, Terry Yr Pristya, Sulistyo Andarmoyo Feb 2021

Parity And Marital Status As Factors Influencing Contraceptive Use Among Adolescents In Indonesia, Anni Fithriyatul Mas'udah, Terry Yr Pristya, Sulistyo Andarmoyo

Kesmas

Adolescent pregnancy has a higher health risk compared to adult pregnancy. One approach to control pregnancy among adolescents is through contraceptive use. The data on contraceptive use has increased in 2018 and is still controversial among adolescents. Thus, it is necessary to determine the factors encou - rag ing the use of contraceptives among adolescents. This study aimed to determine the relation of parity and marital status on contraceptive use among adolescents. This quantitative study used a cross-sectional design. The population of this study was adolescents aged 15–19 years in Indonesia. The total sample of 936 adolescents was selected from …


Low Knowledge And Unawareness Of The Health Promotion As The Determinant Factors In Non-Compliance To The Mass Drug Administration Program, Nissa Noor Annashr, Icca Stella Amalia, Hoa Thi Phuong Dinh Feb 2021

Low Knowledge And Unawareness Of The Health Promotion As The Determinant Factors In Non-Compliance To The Mass Drug Administration Program, Nissa Noor Annashr, Icca Stella Amalia, Hoa Thi Phuong Dinh

Kesmas

From the total population of the community in Kuningan District, 78.61% were taking filariasis drugs in the Mass Drug Administration (MDA) program in 2017. Cilimus Subdistrict became a filariasis-endemic area in Kuningan with 72.39% of the MDA program coverage in 2017 (government target >86%). The purpose of this study was to analyze the determinant factors of compliance with the MDA program. The study was an analytical study with a cross-sectional design and conducted from May to June 2018. The sample of 106 people was taken from the population living in Cilimus Subdistrict, Kuningan District, using a simple random sampling technique. …


Patterns And Determinants Of Open Defecation Among Urban People, Vera Yulyani, Christin Angelina Febriani, Shaharuddin Ms, Dessy Hermawan Feb 2021

Patterns And Determinants Of Open Defecation Among Urban People, Vera Yulyani, Christin Angelina Febriani, Shaharuddin Ms, Dessy Hermawan

Kesmas

At the present time, an estimated of 673 million people defecate in the open space, not in private. Indonesia is a densely populated country with a lot of open defecation (OD) both in urban (37%) and rural areas (43%). Tanjung Karang Pusat Subdistrict is an area in Bandar Lampung City with the highest percentage of OD practice (45%). This study aimed to explore and explain the patterns and determinants of OD among urban people in the Tanjung Karang Pusat Subdistrict in- volving 377 respondents for quantitative analysis. Quantitative data were analyzed using the chi square and regression analysis. After controlling …


Risk Perception For Developing Erectile Dysfunction Among Malaysian Men With Type 2 Diabetes Mellitus, Anuar Mohamad, Hizlinda Tohid, Saharuddin Ahmad, Seng Fah Tong, Mahadir Ahmad Feb 2021

Risk Perception For Developing Erectile Dysfunction Among Malaysian Men With Type 2 Diabetes Mellitus, Anuar Mohamad, Hizlinda Tohid, Saharuddin Ahmad, Seng Fah Tong, Mahadir Ahmad

Kesmas

Risk perception for developing erectile dysfunction (ED) is an appreciation of the susceptibility to having ED and its severity. This study examined this risk perception and its associated factors among 180 men with type 2 diabetes mellitus (T2DM), who claimed not to have ED. This cross sectional study was conducted at a public health clinic using a validated self-administered questionnaire, which assessed participant characteristics, perceived susceptibility to developing ED, perceived severity of ED, and knowledge on risk factors for ED. About 71.1% had an inaccurate perception of susceptibility to developing ED and their perception on its severity was moderate (median …


Determinants Of Exclusive Breastfeeding Practices Of Female Healthcare Workers In Jakarta, Indonesia, Siti Rapingah, Nova Muhani, Besral Besral, Poppy Yuniar Feb 2021

Determinants Of Exclusive Breastfeeding Practices Of Female Healthcare Workers In Jakarta, Indonesia, Siti Rapingah, Nova Muhani, Besral Besral, Poppy Yuniar

Kesmas

The World Health Organization (WHO) recommended that mothers worldwide exclusively breastfeed their infants for the child's first six months to achieve optimal growth, development, and health. Indonesia had not fulfilled the global standard of breastfeeding rate so that there was low coverage of exclusive breastfeeding in East Jakarta, especially for female healthcare workers. This study aimed to determine the factors associated with exclusive breastfeeding practices of healthcare workers. This was a quantitative study using a cross-sectional design. The recruited sample consisted of 85 female public health center workers with infants aged 6-24 months. Data were collected using self-administered questionnaires. Logistic …


Evaluation Of Added Sugar And Sugar-Sweetened Beverage Consumption By University Students, Çağdaş Salih Meric, Nurcan Yabanci Ayhan, Hacı Ömer Yilmaz Feb 2021

Evaluation Of Added Sugar And Sugar-Sweetened Beverage Consumption By University Students, Çağdaş Salih Meric, Nurcan Yabanci Ayhan, Hacı Ömer Yilmaz

Kesmas

Today, increased intake of sugar and sugar-sweetened beverages is seen today as an important factor in the growing prevalence of chronic diseases, such as obesity, obesity-related diabetes, and coronary heart diseases. This study involved 214 university students from the Department of Nutrition and Dietetics of Ankara University, Faculty of Health Science, which was intended to evaluate the consumption of sugar and sugar-sweetened beverages. The frequency of student consumption of beverages and the quantities and amounts of sugar taken with beverages were questioned. The average total amount of sugar added to drinks by the students was 4.69 ± 6.35 gram, while …


Maternal Dietary Quality, Inflammatory Potential And Childhood Adiposity: An Individual Participant Data Pooled Analysis Of Seven European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James Hébert Scd, Fionnuala M. Mcauliffe, Cecily Kelleher, Catherine M. Phillips Feb 2021

Maternal Dietary Quality, Inflammatory Potential And Childhood Adiposity: An Individual Participant Data Pooled Analysis Of Seven European Cohorts In The Alphabet Consortium, Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James Hébert Scd, Fionnuala M. Mcauliffe, Cecily Kelleher, Catherine M. Phillips

Faculty Publications

Background

Mounting evidence suggests that maternal diet influences pregnancy and birth outcomes, but its contribution to the global epidemic of childhood obesity has not as yet been definitively characterized. We investigated whether maternal whole diet quality and inflammatory potential influence childhood adiposity.

Methods

We harmonized and pooled individual participant data from 16,295 mother-child pairs in seven European birth cohorts. Maternal pre-, early-, late-, and whole-pregnancy (any time during pregnancy) dietary quality and inflammatory potential assessed with the Dietary Approaches to Stop Hypertension (DASH) score and the energy-adjusted Dietary Inflammatory Index (E-DII™) score, respectively. Primary outcome was childhood overweight and obesity …


Whole-Exome Sequencing And Hipsc Cardiomyocyte Models Identify Myrip, Trappc11, And Slc27a6 Of Potential Importance To Left Ventricular Hypertrophy In An African Ancestry Population, Marguerite R. Irvin, Praful Aggarwal, Steven A. Claas, Lisa De Las Fuentes, Anh N. Do, C. Charles Gu, Andrea Matter, Benjamin S. Olson, Amit Patki, Karen Schwander, Joshua D. Smith, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amy J. Turner, Deborah A. Nickerson, Dabeeru C. Rao, Ulrich Broeckel, Donna K. Arnett Feb 2021

Whole-Exome Sequencing And Hipsc Cardiomyocyte Models Identify Myrip, Trappc11, And Slc27a6 Of Potential Importance To Left Ventricular Hypertrophy In An African Ancestry Population, Marguerite R. Irvin, Praful Aggarwal, Steven A. Claas, Lisa De Las Fuentes, Anh N. Do, C. Charles Gu, Andrea Matter, Benjamin S. Olson, Amit Patki, Karen Schwander, Joshua D. Smith, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amy J. Turner, Deborah A. Nickerson, Dabeeru C. Rao, Ulrich Broeckel, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Background: Indices of left ventricular (LV) structure and geometry represent useful intermediate phenotypes related to LV hypertrophy (LVH), a predictor of cardiovascular (CV) disease (CVD) outcomes.

Methods and Results: We conducted an exome-wide association study of LV mass (LVM) adjusted to height2.7, LV internal diastolic dimension (LVIDD), and relative wall thickness (RWT) among 1,364 participants of African ancestry (AAs) in the Hypertension Genetic Epidemiology Network (HyperGEN). Both single-variant and gene-based sequence kernel association tests were performed to examine whether common and rare coding variants contribute to variation in echocardiographic traits in AAs. We then used a data-driven …


Hiv/Aids Transmission Dynamics: Modelling The Roles Of Long Distance Truck Drivers, Nyimvua Mbare Feb 2021

Hiv/Aids Transmission Dynamics: Modelling The Roles Of Long Distance Truck Drivers, Nyimvua Mbare

Tanzania Journal of Science

A mathematical model to investigate the roles of long distance truck drivers on HIV transmission dynamics was formulated and analyzed to establish the existence of disease free and endemic equilibrium points. The results show that, the disease free equilibrium point is asymptotically stable when the basic reproduction number is less than unity and unstable otherwise. Furthermore, comprehensive analyses on the two steady states (infection free and endemic) have shown that they are both globally and asymptotically stable. Sensitivity analysis is performed on the reproduction number in order to establish the relative importance of parameters, and it shows that the truck …


Dietary Quality And Dietary Inflammatory Potential During Pregnancy And Offspring Emotional And Behavioral Symptoms In Childhood: An Individual Participant Data Meta-Analysis Of Four European Cohorts, Kinga Polanska, Pawel Kaluzny, Adrien M. Aubert, Liesbeth Duijts, Hanan El Marroun, Wojciech Hanke, James R. Hébert, Barbara Heude, Agnieszka Jankowska, Giulia Mancano, Sara M. Mensink-Bout, Caroline Relton, Nitin Shivappa Mbbs, Mph, Ph.D., Matthew Suderman, Elzbieta Trafalska, Ewelina Wesolowska, Raquel Garcia-Esteban, Mònica Guxens, Maribel Casas, Catherine M. Phillips Feb 2021

Dietary Quality And Dietary Inflammatory Potential During Pregnancy And Offspring Emotional And Behavioral Symptoms In Childhood: An Individual Participant Data Meta-Analysis Of Four European Cohorts, Kinga Polanska, Pawel Kaluzny, Adrien M. Aubert, Liesbeth Duijts, Hanan El Marroun, Wojciech Hanke, James R. Hébert, Barbara Heude, Agnieszka Jankowska, Giulia Mancano, Sara M. Mensink-Bout, Caroline Relton, Nitin Shivappa Mbbs, Mph, Ph.D., Matthew Suderman, Elzbieta Trafalska, Ewelina Wesolowska, Raquel Garcia-Esteban, Mònica Guxens, Maribel Casas, Catherine M. Phillips

Faculty Publications

Background

The impact of maternal diet during pregnancy on child neurodevelopment is of public health and clinical relevance. We evaluated the associations of dietary quality based on the Dietary Approaches to Stop Hypertension (DASH) score and dietary inflammatory potential based on the energy-adjusted Dietary Inflammatory Index (E-DII) score during pregnancy with emotional and behavioral symptoms of offspring at 7 to 10 years of age.

Methods

Individual participant data for 11,870 mother–child pairs from four European cohorts participating in the ALPHABET project were analyzed. Maternal antenatal DASH and E-DII scores were generated from self-completed food frequency questionnaires. Symptoms of depression …