Public Health Commons^™

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Why Cancer?, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum

Henry Ford Hospital Medical Journal

Cancer of the breast and colon are well known to occur with high frequency in families with certain inherited cancer syndromes. These cancers also occur with increased frequency in families which do not have a recognizable genetic cancer syndrome. The fact of familial occurrence can be used to identify people with increased risk of cancer. In high-risk people methods for early detection can be developed which may reduce morbidity and mortality from these cancers, as has been done for certain inherited cancer syndromes.

External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel

Henry Ford Hospital Medical Journal

External beam radiation therapy for unresectable non-small cell carcinoma of the lung has produced significant survival in patients with disease limited to one hemithorax. New approaches to improve the results of radiation treatment of these patients include interstitial implantation, the use of hypoxic cell sensitizers, biologic response modifiers, as well as changes in the technique of radiation therapy. This includes the use of modern computerized tomographic scanning technology for better definition of tumor volume as well as the use of two fractions per day in the treatment of non-small cell carcinoma of the lung. Initial results of these studies are …

The Spectrum Of B Cell Neoplasia, Michael J. Deegan

Henry Ford Hospital Medical Journal

Recent progress in our understanding of the immune system and the development of new techniques that permit the precise identification of lymphocytes have permitted a reexamination of lymphoid neoplasms. Most of the non-Hodgkin's lymphomas and lymphocytic leukemias have been characterized as T or B cell neoplasms and have been shown to possess features similar to those expressed by normal lymphoid cells at different stages of maturation. The clinical significance and therapeutic implications of these discoveries are now being explored. This paper presents a concise overview of the differentiation of human B lymphocytes, the surface and cytoplasmic markers that permit their …

Preoperative Chemotherapy And Irradiation In The Treatment Of Soft Tissue Sarcomas Of The Lower Extremities: Preliminary Report Of Experience At Henry Ford Hospital, S. David Nathanson

Henry Ford Hospital Medical Journal

The development of effective chemotherapy and improved techniques of radiation therapy offer the possibility of managing soft tissue sarcomas so that surgery may need to be less radical than in the past and amputation can be avoided. The low rates of local-regional and systemic recurrence that have resulted from using innovative combinations of chemotherapy, radiation therapy, and conservative surgery encouraged us to use preoperative intraarterial adriamycin (doxorubicin) with or without radiation therapy for three cases of soft tissue sarcomas of the lower extremities. The rationale for this therapy is also discussed.

The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak

Henry Ford Hospital Medical Journal

For patients in whom unexplained elevations in SGOT and SGPT concentrations are found, determination of the serum iron level is recommended to screen for asymptomatic precirrhotic hemochromatosis. Care must be taken to differentiate between hereditary hemochromatosis and secondary iron accumulation due to liver disease.

Is Normal "Normal"?, Craig C. Foreback

Henry Ford Hospital Medical Journal

No abstract provided.

Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.

Henry Ford Hospital Medical Journal

The immunosuppressive properties of corticosteroids are well established and cause a depression of pulmonary defense mechanisms. We report the case of a patient treated with short-term corticosteroids for an exacerbation of chronic obstructive lung disease who developed a multiple organism pneumonia.

Neurosonology: An Update, Beatrice L. Madrazo, Manuel Dujovny, Juan Fuentes, Michael A. Sandler, Madelyne Galvin

Henry Ford Hospital Medical Journal

Recent technological advances in diagnostic ultrasound have resulted in the development of high-resolution, portable real-time scanners. In neurological ultrasound, these devices have been particularly useful for detecting intracranial hemorrhage in premature infants. Sonography is now being used during neurosurgical procedures to help in localizing masses for resection and biopsy, as well as in the placement of shunt catheters. The applications of neurosonology and our experience with intraoperative neurosonology are reported in this review.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Mosquitoes As Vectors Of Disease In Minnesota, John W. Washburn

Journal of the Minnesota Academy of Science

Diseases due to mosquito-borne viruses occur every summer in Minnesota. The incidence of Western encephalitis and LaCrosse encephalitis is usually low, but outbreaks of Western encephalitis have occurred in the past. Evidence of Jamestown Canyon virus activity has been found in Minnesota. This virus may represent a newly-recognized cause of central nervous system disease and encephalitis. The epidemiology of the mosquito-borne encephalitis viruses found in Minnesota and the methods of disease surveillance and control are discussed.

Ua35/11 Student Honors Research Bulletin, Wku Honors Program

WKU Administration Documents

The WKU Student Honors Research Bulletin is dedicated to scholarly involvement and student research. These papers are representative of work done by students from throughout the university.

• Albin, Bettye. Hawthorne's Narrator in the Blithedale Romance: A New Cover for an Old Friend
• Allen, Christopher. With Just Pride: The Naval History of the Warships USS Enterprise
• Barrett, Shelly. Structuralism
• Bolton, Joe. Wallace Stevens and Twentieth Century Aesthetics
• Bush, Paul. The Acceptance of Grace in Flannery O'Connor's Short Stories
• Gasparello-Moore, Nina. A Comparison of a Naïve and Simple Regression Forecasting Model for the Dow Jones Industrial Average
• Henry, Lynn. The Bureaucratic and …

Effect Of Membrane Filtration Of Antimalarial Drug Solutions On In Vitro Activity Against Plasmodium Falciparum, J. Kevin Baird, C. Lambros

United States Public Health Resources

Antimalarial activities ofchloroquine, mefloquine, amodiaquine, and quinine in vitro against Plasmodium falciparum were diminished as a consequence ofmembranefiltration. Filtered drug solutions gave ID₅₀ values up to 25-fold greater than those of non-filtered (ethanol-sterilized) drug solutions. Loss ofactivity byfiltration was overcome by increasing the drug concentration prior to filtration. Water solutions filtered through Millex-GSfilter units consistently showed an absorbance maximum at 277 nm, accompanied by a lesser peak at 225 nm. Water filtrates from Nucleopore and Millex-G Vfilters showed no absorbance at 277 nm and only slight absorbance was evidentfor the Gelmanfilter unit. Activity losses were attributed to extractable contaminating …

Minnesota's Response: The Mosquito Research Program, John Washburn, Nancy Read

Journal of the Minnesota Academy of Science

The Minnesota Mosquito Research Program (MMRP) was established in September 1984 in response to a request by Governor Perpich. The Minnesota Department of Health (MDH), as the lead agency, brought together a Working Group of distinguished North American experts to discuss the problems related to mosquito research and control. This Working Group- with advice from legislators and representatives from the community, environmental groups, and state and federal agencies- made recommendations for the development of a mosquito research and control program in Minnesota.

The Working Group divided its recommendations into two areas, research and administrative structure. An extensive research program in …

Vitamin D In Clinical Medicine, John G. Haddad

Henry Ford Hospital Medical Journal

No abstract provided.

Pathogenesis Of Hyperparathyroidism, Louis M. Sherwood

Henry Ford Hospital Medical Journal

No abstract provided.

Bone Disease In Uremia, Jack W. Coburn

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Frances And Anthony D'Anna International Symposium On Clinical Disorders Of Bone And Mineral Metabolism, Boy Frame, John T. Potts

Henry Ford Hospital Medical Journal

No abstract provided.

Recent Developments In Bone Physiology, A. M. Parfitt

Henry Ford Hospital Medical Journal

No abstract provided.

Pseudohypoparathyroidism And Related Disorders, G. D. Aurbach

Henry Ford Hospital Medical Journal

No abstract provided.

Radiology Of Metabolic Bone Disease: Workshop Report, S. R. Kottamasu, D. S. Rao, H. E. Meema, H. K. Genant

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Applications Of Parathyroid Hormone Assays, John T. Potts Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Assessment Of Trabecular Bone Status, A. M. Parfitt

Henry Ford Hospital Medical Journal

No abstract provided.

Assessment Of Mineral And Matrix Turnover, Stephen M. Krane

Henry Ford Hospital Medical Journal

No abstract provided.

The Management Of Primary Hyperparathyroidism, Michael Kleerekoper

Henry Ford Hospital Medical Journal

No abstract provided.

Parathyroid-Mediated Bone Loss, Sudhaker D. Rao

Henry Ford Hospital Medical Journal

No abstract provided.