Public Health Commons^™

Clinical And Laboratory Features Of Small Left Atrial Myxomas, Gerardo A. Polanco, Mohsin Alam, Allan M. Haggar, Remigio Garcia

Henry Ford Hospital Medical Journal

No abstract provided.

A Suggested New Approach To Supraventricular Tachydysrhythmia After Coronary Bypass Surgery, Walter Kao, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Toxic Shock-Like Syndrome Associated With Necrotizing Streptococcus Pyogenes Infection, Thomas J. Connolly, Donald J. Pavelka, Eugene F. Lanspa, Thomas L. Connolly

Henry Ford Hospital Medical Journal

Two patients with toxic shock-like syndrome are presented. Both patients had necrotizing cellulitis due to Streptococcus pyogenes, and both patients required extensive surgical debridement. The association of Streptococcus pyogenes infection and toxic shock-like syndrome is discussed.

Ulceroglandular Tularemia: A Typical Case Of Relapse, Stanley D. Miller, Michael B. Snyder, Michael Kleerekoper, Colby H. Grossman

Henry Ford Hospital Medical Journal

Tularemia is an infectious disease that continues to occur sporadically and in epidemics in the United States. It is characterized as an acute febrile illness with constitutional symptoms associated with skin, glandular, respiratory, or gastrointestinal involvement. Tularemia usually can be treated effectively with streptomycin. Relapse most often occurs when patients are treated with bacteriostatic agents such as chloramphenicol or tetracycline. We present a case of ulceroglandular tularemia distinguished by its relapse after initial streptomycin/doxycycline therapy and subsequent slow response to additional streptomycin.

Orf: A Case Report, Brent W. Mohr, David Katz

Henry Ford Hospital Medical Journal

Ecthyma contagiosum (orf), a viral disease endemic to sheep and goats, can be zoonotically transmitted to humans through contact with infected animals. While the disease is common among sheep and goat herders worldwide, it comes to medical attention infrequently since it is generally a mild self-limited illness. We recently treated a healthy 36-year-old female who presented with bullous lesions on her fingers and a diffuse macular rash which had developed after antibiotic therapy for her bullae. She had been caring for her neighbor's goats which had recently been ill with "sore mouth." We discuss this case of orf and review …

Early Detection Of Hereditary Medullary Thyroid Cancer With Polymorphic Dna Probes, Steven A. Narod, Hagay Sobol, Isabelle Schuffenecker, R. Alan B. Ezekowitz, Gilbert M. Lenoir

Henry Ford Hospital Medical Journal

We have performed linkage analysis on 32 families with hereditary medullary thyroid cancer (MTC) wilh seven polymorphic DNA probes situated near the centromere of chromosome 10. Nineteen of these families were affected with multiple endocrine neoplasia type 2A (MEN 2A), and the remainder had MTC without pheochromocytoma. There were no instances of recombination between the MEN 2 A susceptibility gene and the IRBP.H4 marker. Two other probes, TBM.34 and MCK2, are also tightly linked(θ = 0.00 and θ = 0.02. respectively). Because TBM.34 and IRBP.H4/MCK2 are situated on opposite sides of the MEN 2A gene, screening with flanking DNA markers …

Genetic Mechanisms Of Neoplasia In Men 2, Charles E. Jackson, Robert A. Norum

Henry Ford Hospital Medical Journal

Several possible mechanisms for the initiation and progression of tumors in multiple endocrine neoplasia type 2 (MEN 2) merit consideration. Localization of MEN2A to the pericentromeric area of chromosome 10 indicates the site of the initial mutagenic event but does not explain the tissue specificity observed. The consistency of tissue involvement within families, despite the variability between families, suggests that the tumors result from separate but contiguous tissue-specific genes arranged in a particular linear order. Linkage studies in MEN 2A and 2B families are compatible with this contiguous gene theory. Data suggest that Knudson's two-mutational-event theory is applicable in MEN2, …

Anthropometric Parameters In Public School Students And Seventh-Day Adventist Vegetarian And Meat-Eating Students, Joan Sabaté-Casellas

Loma Linda University Electronic Theses, Dissertations & Projects

Concerns have been expressed for the ability of some vegetarian diets to support normal growth of children. Animal protein or meat intake showed a positive relationship to attained height in children from developing countries. In this study, the relationship between meat intake/vegetarian status and physical growth was investigated in children living in California.

Height and weight were collected on 2,272 Caucasian children aged 6-18 years attending Seventh-day Adventist (SDA) or public schools who participated in a two year longitudinal study. Age-, sex-, and school-specific mean heights and weights were at or above the national reference values. Sex-specific, age-adjusted regression analysis …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Improvement In Left Ventricular Systolic Function After Pericardiocentesis: Case Report, Gary S. Salem, Robert A. Genovese, Mohsin Alam, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Screening For Adenocarcinoma Of The Prostate, Brian J. Miles

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Fibrinolysis In Acute Monocytic Leukemia, Ellis J. Van Slyck, Sundara B. K. Raman, Nalini Janakiraman

Henry Ford Hospital Medical Journal

We present the case of a young man with acute monocytic leukemia (French-American-British classification:M5) and systemic hyperfibrinolysis with severe bleeding. Although fibrinolysis is usually mild and secorulary to disseminated intravascular coagulation, its role as a primary and dominant factor in rare cases of leukemia warrants that its presence be sought as a cause of abnormal bleeding. Decreased serum plasminogen and increased serum plasmin determined by synthetic substrate assay and a negative protamine paracoagulation test are crucial findings. Use of high-dose epsilon-aminocaproic acid was effective in treating this complication. A transient increase in fibrinolytic activity coincident with the early effect of …

Pleural Effusion In Michigan Caused By Coccidioides Immitis After Travel To An Endemic Area, Christopher M. Hughes, Paul A. Kvale

Henry Ford Hospital Medical Journal

Primary coccidioidal disease is rarely diagnosed in the midwest in the nonimmunocompromised host. Since coast-to-coast travel is common today, many patients may become exposed to Coccidioides immitis while traveling in endemic areas. We present a case of acute coccidioidal pleural effusion in a Michigan woman who had recently visited northeastern Arizona. Her travel history was the single most important factor in the eventual diagnosis of coccidioidal pleural effusion.

Histopathologic Diagnosis And Classification Of Prostate Adenocarcinoma: Biologic Significance, Jill M. Peters, John D. Crissman

Henry Ford Hospital Medical Journal

Early diagnosis and accurate, biologically meaningful classification of prostate neoplasia remain important goals. The relation of evolving clinicopathologic concepts of histologic appearances to potential tumor progression is a major advance in classification of prostatic neoplasia. The criteria for recognizing incidental or "occult" stage A-l adenocarcinomas remain problematic in diagnosis, and focal neoplasms with little or no propensity to progression must be differentiated from cancers with a high likelihood of aggressive behavior. Current histologic grading systems in classifying prostate adenocarcinoma accurately identify two cancer subsets: 1) focal well differentiated tumors which rarely progress, and 2) diffuse poorly differentiated tumors which invariably …

Staging Carcinoma Of The Prostate, Joseph C. Cerny

Henry Ford Hospital Medical Journal

No abstract provided.

Hormonal Management Of Advanced Adenocarcinoma Of The Prostate, Brian J. Miles

Henry Ford Hospital Medical Journal

No abstract provided.

Advances In The Diagnosis Of Urothelial Neoplasia, John D. Crissman, Richard J. Zarbo, Terri Johnson, V. Ramesh Babu, Fazlul H. Sarkar, Brian J. Miles, Joseph C. Cerny

Henry Ford Hospital Medical Journal

Urothelial neoplasia is a unique cancer in that it consists of a spectrum of tumors with different biologic behaviors. The most common urothelial neoplasm is the low grade superficial papillary carcinoma or papilloma which may recur numerous times but does not result in significant morbidity or mortality. A variant of the superficial papillary carcinoma, which represents approximately 10% of the tumors, is the noninvasive papillary neoplasm which progresses to a less differentiated invasive transitional cell carcinoma (TCC). Considerable effort has been directed at identifying which of the superficial well differentiated papillary tumors will persist, recur and progress to invasive cancer …

Effect Of Cyclosporine On The Rate Of Renal Function Recovery After Renal Transplantation, Francis Dumler

Henry Ford Hospital Medical Journal

To assess the effect of cyclosporine therapy on the rate of renal function recovery after renal transplantation, patients with no clinical evidence of rejection and who were treated with either cyclosporine or azathioprine in addition to steroid therapy were studied (n = 74). Of the patients with immediate renal function (n = 57), those receiving organs from living, related donors had a faster recovery rate of glomerular filtration than patients with cadaveric grafts (azathioprine, 15 ± 2 versus 7 ± 1 mL/min/day, P = 0.0001; cyclosporine, 14 ± 3 versus 6 ± 1 mL/min/day, P = 0.001). Recipients of cadaveric …

Quinidine-Induced Immune Thrombocytopenia, Mansoor N. Saleh, Nadhav Dhodaphar, Karen Allen, Albert F. Lobuglio

Henry Ford Hospital Medical Journal

We have identified six cases of quinidine-induced immune thrombocytopenia based on clinical evidence and in association with elevated amounts of platelet surface IgG. The degree of thrombocytopenia did not correlate with severity of clinical symptoms, nor did it predict the amount of IgG on the platelet surface. Three of the patients recovered promptly after drug discontinuation alone whereas the other patients received additional corticosteroid therapy. The clinical presentation, mode of diagnosis, and therapeutic considerations in the treatment of drug-induced thrombocytopenia are discussed.

Surgical Management Of Spinal Epidural Disease: An Update, Jack P. Rock, Dale V. Hoekstra, Henry H. Schmidek

Henry Ford Hospital Medical Journal

Management of spinal cord compression from metastatic malignant disease remains unsatisfactory. Results of surgical decompression are at best less than those of radiation therapy alone. However, new surgical approaches now focus on removing the anterior-situated tumor tissue which produces neural compression in about 85% of the cases. The results of these procedures that allow removal of the ventrally compressing tumor show significant improvement in the management of patients with spinal epidural disease. We review the surgical strategy of these new approaches and the attendant results.

Echo-Doppler Features Of Pulmonary Valve Endocarditis, Jihad Bitar, Mohsin Alam

Henry Ford Hospital Medical Journal

Three patients with fever and pneumonitis were found to have pulmonary valve vegetations by echocardiography. Pulsed and color flow Doppler studies demonstrated mild to moderate pulmonary valve insufficiency in these patients. All patients responded to the appropriate antibiotics without requiring valve surgery. Echocardiography is of value in diagnosing pulmonary valve endocarditis and should be considered in every patient with recurrent pneumonitis.

Digitalis Intoxication Or Intrinsic Conduction System Disease, Hooman Mahdyoon, Howard S. Rosman, Demetrios N. Mermiges, Mihai Gheorghiade

Henry Ford Hospital Medical Journal

No abstract provided.

Cerebral Infarction Associated With Cocaine Use, Iliana Meza, Carlos A. Estrada, Justo A. Montalvo, Walter N. Hidalgo, Jennie Andresen

Henry Ford Hospital Medical Journal

We report the case of a young man with an acute infarction of the left putamen and caudate nucleus, whose symptoms appeared six hours after intranasal use of approximately 0.5 g of cocaine hydrochloride. It seems probable that in this patient cocaine consumption played a role in the development of stroke.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Adenocarcinoma Of The Prostate: An Overview, Brian J. Miles, Robert Chapman, Joseph C. Cerny

Henry Ford Hospital Medical Journal

No abstract provided.

Agenda For Action - Casco Bay, Department Of Environmental Protection

Maine Collection

Agenda For Action - Casco Bay

Department of Environmental Protection, Augusta, Maine (January, 1989)

Contents: Introduction / The Problems : Bacteria, Toxics, Nutrients / The Solutions / Recommendations / References

Maine Nonpoint Source Pollution Assessment Report, Bureau Of Water Quality Control

Maine Collection

Maine Nonpoint Source Pollution Assessment Report

Prepared by the Maine Department of Environmental Protection, Bureau of Water Quality Control, Augusta, Maine 1989.

Contents: Executive Summary / Introduction / Methodology / Statewide Water Quality Summary / State And Local Agency Programs for Control of Nonpoint Source Pollution / Process for Identification of Best Management Practices and Associated Standards / List of References / List of Figures / List of Tables

From The Gulf To The Rio Grande: Human Adaptation In Central, South, And Lower Pecos Texas, Thomas Hester, Stephen L. Black, D. Gentry Steele, Ben W. Olive, Anne A. Fox, Karl Reinhard, Leland C. Bement

Karl Reinhard Publications

The South Texas area, Region 3 of the Southwestern Division, U.S. Army Corps of Engineers, is synthesized from archeological and bioarcheological perspectives. Three distinct geographic units within Region 3 are treated in detail: Central Texas Plateau Prairie, South Texas Plains, and Lower Pecos Canyonlands. More than 11,000 years of human adaptation are chronicled for this area, stretching from the Gulf of Mexico to the Rio Grande along the border with northeastern Mexico. Particular attention is devoted to a consideration of the region's prehistoric record; significant problems and data gaps are outlined. For the first time, a compilation has been done …

A Mimbres Burial With Associated Colon Remains From The Nan Ranch Ruin, New Mexico, Harry J. Shafer, Marrianne Marek, Karl J. Reinhard

Karl Reinhard Publications

The skeletal remains of an adult male associated with desiccated tissue and a coprolite were recovered from an apen-air midden deposit at the NAN Ranch Ruin (LA15049)) a large Mimbres site in Grant County) New Mexico. The find dates to about A.C. 1000-1100. Identifiable macroscopic elements in the caprolite consist offi nely fragmented corn and tiny seed fragments of an unknown plant. High amounts of willow (Salix) and mustard (Brassicaceae) pollen may indicate the ingestion of medicinal plants to combat a deteriorating health condition. The individual was approximately 35 -40 years old at the time of death and suffered from …

Bioarcheological Synthesis For "From The Gulf To The Rio Grande: Human Adaptation In Central, South, And Lower Pecos Texas", Karl Reinhard, Ben W. Olive, D. Gentry Steele

Karl Reinhard Publications

One of the main problems encountered in the review of the bioarcheology of Region 3 has been the limited number of sites where human skeletal material has been adequately recovered and analyzed. In the preceding chapter it was documented that less than 30% of the burials recovered from recorded sites have been reported in published literature. It was further estimated that of the 323 sites with burials, no more than 80 sites have published detailed bioarcheological reports on the burials recovered. Only 50 of these 80 reports provide individual descriptions of each burial which facilitate subsequent analyses and evaluation.

Four …