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Articles 1921 - 1950 of 6880
Full-Text Articles in Public Health
A Review Of Research On The Potential Value And Realistic Dilemma For Homework In Physical Education, Yue Xu, Chenyu Jia, Zhihua Yin
A Review Of Research On The Potential Value And Realistic Dilemma For Homework In Physical Education, Yue Xu, Chenyu Jia, Zhihua Yin
International Journal of Physical Activity and Health
Homework in physical education (PE) has become a central strategy of educational reform movements (Novak & Lynott, 2015). A Chinese policy called “the Double Reduction” provides an opportunity for the implementation of PE homework. There are abundant studies about homework in subjects like English, Math, Science, etc., but relatively few studies have been devoted specifically to PE homework. The primary purpose of this study was to analyze the value and dilemma of PE homework, with the goal of identifying the major contributions to the research knowledge base. We followed three parts to conduct the review: a) literature was searched using …
Characteristics And International Enlightenment Of Adolescent Physical Literacy Cultivation In Wales, Han Meng, Zhihua Yin
Characteristics And International Enlightenment Of Adolescent Physical Literacy Cultivation In Wales, Han Meng, Zhihua Yin
International Journal of Physical Activity and Health
School education has focused on the fields of students’ literacy instead of specific subjects. The cultivation of physical literacy (PL) is gaining more and more attention in western countries, but few studies on this topic were found in China. The purpose of this research was to unfold the experience of Welsh adolescent PL and to provide enlightenment to China. This study analyzed the cultivation of Welsh adolescents’ PL through literature, logical analysis, and semi-structured interviews with eleven experts. The constant comparative method was used to analyze interview transcripts for common themes. During analysis, triangulation, negative case checks, member checks, and …
Effects Of High Intensity Interval Training On Children’S Health And Physical Fitness, Jinlong Xie, Yilan Li
Effects Of High Intensity Interval Training On Children’S Health And Physical Fitness, Jinlong Xie, Yilan Li
International Journal of Physical Activity and Health
The effect of high intensity interval training on children’s health is the focus of experts and scholars worldwide. After the outline of “Building a Strong Country in Sports” was issued in 2019, China’s attention to sports has reached a peak. However, the proportion of obese or myopic children in schools at all levels is still high, and the problem of low physical fitness of Chinese students is still serious. The purpose of this study was to review previous studies to explore the effects of high intensity interval training on children’s health and physical fitness. We reviewed relevant literature both in …
Measuring Invariance Of Theory Of Planned Behavior Model On Online Fitness Program Participation During The Covid-19 Pandemic, Ran Wei, Yuanlong Liu, Brooks Applegate, Colin Cork
Measuring Invariance Of Theory Of Planned Behavior Model On Online Fitness Program Participation During The Covid-19 Pandemic, Ran Wei, Yuanlong Liu, Brooks Applegate, Colin Cork
International Journal of Physical Activity and Health
Theory of Planned Behavior (TPB) is one of the most frequently cited and most influential models to explain and predict human intentions and behaviors (Ajzen, 1991, 2011; Kim & James, 2016), which include physical activity and exercise. However, the dimensionality of TPB has not been examined in the context of online fitness program (OFP) participation during the COVID-19 pandemic. The purpose of this study was to examine the TPB measurement parameters of the factorial models and determine the generalizability of the psychological constructs of the TPB model on gender groups and whether COVID-19 affected annual income groups. The participants were …
Research On Evaluation Index System Of Sports Events Over Urban Development Based On Symbiosis Theory, Hanzhi Dai
Research On Evaluation Index System Of Sports Events Over Urban Development Based On Symbiosis Theory, Hanzhi Dai
International Journal of Physical Activity and Health
With the development of economic globalization, sports events have become a strategic tool that is used for enhancing the competitiveness of the city and achieving the government’s goal. Nowadays, a myriad of cities takes organizing sports events as the goal of urban development. However, what is the relationship between sporting events and urban development? How to build an evaluation index system to measure the relationship between urban development and sports events? How are sports events coordinated with urban development? These issues have not yet been thoroughly investigated. This study attempts to analyze the relationship and mechanism between urban development and …
History, Development, And Enlightenment Of Adapted Physical Education National Standards, Yuting Song, Cuixiang Dong, Liu Ji
History, Development, And Enlightenment Of Adapted Physical Education National Standards, Yuting Song, Cuixiang Dong, Liu Ji
International Journal of Physical Activity and Health
As the total number and proportion of individuals with disabilities worldwide are increasing, the international community is paying more and more attention to the equal education rights of individuals with disabilities. Since the Individuals with Disabilities Education Act issued in 1975, physical education (PE) played a significant part in special education. According to the requirements of the United States federal legislation, a national certification examination system has been established and developed subsequently to better promote the development of physical education for children with disabilities. The National Consortium for Physical Education for Individuals with Disabilities (NCPEID) has formulated the Adapted Physical …
Relationship Between Physical Activity And Mental Health In Chinese Engineering College Students During Covid-19, Zongyu Liu, Xiuhan Zhao
Relationship Between Physical Activity And Mental Health In Chinese Engineering College Students During Covid-19, Zongyu Liu, Xiuhan Zhao
International Journal of Physical Activity and Health
The issue of mental health among college students is concerning during COVID-19 outbreak. Since engineering college students are vulnerable to mental health issues, the objectives of this study were: (1) to analyze the relationship between physical activity, parental psychological control, basic psychological needs, anxiety, and mental health in Chinese engineering college students during COVID-19 pandemic; and (2) to examine the mediation effect of anxiety between the relationship of basic psychological needs and mental health. A cross-sectional study was conducted among several universities in Shandong Province, China. We randomly selected 254 Chinese engineering college students. Participants completed the Physical Activity Rating …
The Restrictive Factors And Practical Path Of Sports-Medical Integration Under The Background Of Covid-19 Pandemic, Yonghuan Chen, Yanan Jiang, Xiangning Yan
The Restrictive Factors And Practical Path Of Sports-Medical Integration Under The Background Of Covid-19 Pandemic, Yonghuan Chen, Yanan Jiang, Xiangning Yan
International Journal of Physical Activity and Health
This paper explored the restrictive factors of realizing the integration of sports and medicine in China under the background of “COVID-19 pandemic” and analyzed the path of realizing the integration of sports and medicine by combining it with “Healthy China” strategy and “National Fitness Program”. We used document and expert interview method. In the new era, people’s desire for a better life has become the most extensive demand, and the sudden outbreak of epidemic makes people’s demand for health become the first demand. The importance of people’s health raises “Healthy China” as the national development strategy, which has become the …
Experimental Research On The Teaching Mode Of Cooperation And Competition In Physical Education, Xuelin Pang, Zhengze Zhang
Experimental Research On The Teaching Mode Of Cooperation And Competition In Physical Education, Xuelin Pang, Zhengze Zhang
International Journal of Physical Activity and Health
There are great differences in skill levels among students in the class. It should be the focus of our work to improve students to the greatest extent through teaching, gradually narrow the gap between individuals, and improve the overall teaching quality. Therefore, the purpose of this study was to examine the effects of the teaching mode of cooperation and competition. The research group conducted two rounds of teaching experiments in Harbin Engineering University. The first round of experiments adopted an equal group pre-test and post-test experimental design. Solomon’s four group design was used in the second round of experiment. The …
Effects Of Peer Support On Body Composition And Circumference In Chinese University Students, Chuhao Li, Lin Chen, Yi Xiang, Yongshen Lu, Shiwei Mo
Effects Of Peer Support On Body Composition And Circumference In Chinese University Students, Chuhao Li, Lin Chen, Yi Xiang, Yongshen Lu, Shiwei Mo
International Journal of Physical Activity and Health
This study aimed to understand the effects of adopting peer support in physical education (PE) class on university students’ body composition and circumference. Two university PE classes were recruited and assigned randomly to class with peer support (CWP; n=41; 8 underweight, 23 normal weight, 5 overweight, and 5 obesity; mean age=19.6±1.3yrs; height=169.5±8.0 cm) or class without peer support (CWOP; n=41; 9 underweight, 23 normal weight, 4 overweight, 5 obesity; mean age=19.3±1.1yrs; height=169.1±6.7 cm). Both classes adopted 16 weeks the same bodyweight management program for fitness promotion for 90 min/session/week (15 min warm-up, 60 min main training, 15 min cool-down). Students …
Difficulties And Solutions Of Intelligent Fitness Assistance Device To Help Students With Weak Physical Fitness, Yucai Liu
International Journal of Physical Activity and Health
Intelligent fitness assistance device is an intelligent (electromechanical or other power) assistance device. According to the actual situation of students with weak physical fitness, the device gives intelligent help. In order to reduce the difficulty of fitness and improve the fitness efficiency, this study introduced the relevant theories and technologies in the field of intelligent electromechanical into students' fitness. We collected and sorted out corresponding theories and technologies from the field of physical fitness and the field of intelligent electromechanical assistance, sought the integration point of the two interdisciplinary disciplines, took electromechanical assistance as the main technical support, take students …
Theoretical Discussions And Pathways Of Including Physical Education In The College Entrance Examination, Xiaoqiang Qian
Theoretical Discussions And Pathways Of Including Physical Education In The College Entrance Examination, Xiaoqiang Qian
International Journal of Physical Activity and Health
Under the background of the integration of sports and education, the study explored the feasibility and path of including physical education in the College Entrance Examination. Comprehensive literature and expert interviews and other methods were used to analyze the needs of including physical education in the College Entrance Examination. The specific theories are as follows: (a) “including physical education in the College Entrance Examination” can be an important entry point to promote the integration of sports and education and plays a key role of the test baton; (b) Policies that satisfy most stakeholders and conform to public interests at the …
Analysis And Prospect Of Research Progress Of Health Education Curriculum In China, Xue Wan, Haohui Liu, Zhihua Yin
Analysis And Prospect Of Research Progress Of Health Education Curriculum In China, Xue Wan, Haohui Liu, Zhihua Yin
International Journal of Physical Activity and Health
The purpose of this study was twofold: 1) review research results of health education in China and help readers gain a better understanding of the current profiles of research in health education curriculum and 2) provide a theoretical basis for future research in health education curriculum. Using key words such as health education curriculum on Chinese National Knowledge Infrastructure (CNKI), we searched and finally obtained 7287 articles. By using the visual analysis function of CNKI, we also analyzed the overall trend of research in Health Education Curriculum. Review of the articles found that the overall trend of research in health …
Exercise Prescription In Patient With Different Complications Of Leukemia: Recommendations For Clinical Practice, Yanzhong Chen
Exercise Prescription In Patient With Different Complications Of Leukemia: Recommendations For Clinical Practice, Yanzhong Chen
International Journal of Physical Activity and Health
Common treatment of leukemia will have side effects on nerve function, affecting the patient's physical function, which makes patients often accompanied by infection, bone and joint pain, fatigue and other symptoms. Exercise can improve the level of body function, enable patients to tolerate stronger chemotherapy during treatment, help improve the survival rate and recovery chances of patients, and has been used as an effective means to promote recovery. Recommendations for leukemia and exercise have been primarily based on the results of existing relevant studies. To provide more targeted recommendations for the leukemia, we gathered evidence for the efficacy of exercise …
Construction Of Evaluation System Of Effectiveness Of Supply Based On Spatial Perspective, Tienan Song, Haikuo Yu
Construction Of Evaluation System Of Effectiveness Of Supply Based On Spatial Perspective, Tienan Song, Haikuo Yu
International Journal of Physical Activity and Health
The requirement of "building a higher-level National Fitness Public Service system centering on meeting the needs of the people" by the Chinese State Council is to guarantee and satisfy the demand of public through effective supply. However, despite of the clear purpose of the task, there is still a gap between the actual and the expected status of National Fitness Public Service supply. Based on the characteristics of the perspective of space, the purpose of this study is to examine how to measure and achieve the effectiveness of National Fitness Public Service’s supply. By reviewing the literature, relevant results of …
Effect Of Physical Exercise On Life Satisfaction Of Chinese Primary Students: The Chain Mediating Role Of Self-Confidence And Resilience, Huan-Yu Li, Bo Shen, Jun Yan, Ai-Guo Chen, Ting Zhang
Effect Of Physical Exercise On Life Satisfaction Of Chinese Primary Students: The Chain Mediating Role Of Self-Confidence And Resilience, Huan-Yu Li, Bo Shen, Jun Yan, Ai-Guo Chen, Ting Zhang
International Journal of Physical Activity and Health
Life satisfaction is an overall cognitive evaluation of an individual's living condition for the most of time or over a certain period of time according to the standard of one’s own choice. It is an important psychological variable in the developmental stage of children and adolescents. Some studies had shown that life satisfaction was closely related to children's and adolescents' mental health levels, including their emotional and behavioral conditions. However, the Blue Book for Children: China Children's Development Report (2020) published by China Children's Center stated that Chinese students did not fare well in terms of life satisfaction. Previous studies …
Sit Less, Move More: A National Study Of Physical-Activity Behavior And Cancer, Stella O. Nwogugu
Sit Less, Move More: A National Study Of Physical-Activity Behavior And Cancer, Stella O. Nwogugu
Dissertations, Theses, and Capstone Projects
Background: Physical activity is associated with lower risks of cancer, the second leading cause of death among Americans. Yet, sedentary behavior is the prevailing lifestyle for about 80% of American adults. Additionally, cancer survivors remain significantly inactive, even though physical activity has been shown to decrease risk of cancer and cancer recurrence, improve tolerance of cancer therapy, and reduce mortality. This research explores the relative impact of personal agency, social support, and key demographic variables on physical-activity behavior for a national sample of adults as well as how these relationships differ for cancer survivors and their counterparts.
Methods: Using the …
How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu
How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu
Children’s Nutrition Research Center Staff Publications
Background: eHealth interventions using active video games (AVGs) offer an alternative method to help children exercise, especially during a pandemic where options are limited. There is limited data on costs associated with developing and implementing such interventions.
Objectives: We quantified the costs of delivering an eHealth RCT intervention among minority children during COVID-19.
Methods: We categorized the total trial cost into five subcategories: intervention material development, advertising and recruitment, intervention delivery, personnel salaries, and COVID-19-related equipment costs.
Results: The total RCT cost was $1,927,807 (Direct: $1,227,903; Indirect: $699,904) with three visits required for each participant. The average cost per participant …
How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu
How Much Did It Cost To Develop And Implement An Ehealth Intervention For A Minority Children Population That Overlapped With The Covid-19 Pandemic?, Alexandra Monashefsky, Dar Alon, Tom Baranowski, Tiago V Barreira, Kelly A Chiu, Amy Fleischman, Melanie C Green, Shirley Huang, Ronald C Samuels, Caio Victor Sousa, Debbe Thompson, Amy S Lu
Children’s Nutrition Research Center Staff Publications
Background: eHealth interventions using active video games (AVGs) offer an alternative method to help children exercise, especially during a pandemic where options are limited. There is limited data on costs associated with developing and implementing such interventions.
Objectives: We quantified the costs of delivering an eHealth RCT intervention among minority children during COVID-19.
Methods: We categorized the total trial cost into five subcategories: intervention material development, advertising and recruitment, intervention delivery, personnel salaries, and COVID-19-related equipment costs.
Results: The total RCT cost was $1,927,807 (Direct: $1,227,903; Indirect: $699,904) with three visits required for each participant. The average cost per participant …
Genetic Effect On Body Mass Index And Cardiovascular Disease Across Generations, Chloé Sarnowski, Matthew P Conomos, Ramachandran S Vasan, James B Meigs, Josée Dupuis, Ching-Ti Liu, Aaron Leong
Genetic Effect On Body Mass Index And Cardiovascular Disease Across Generations, Chloé Sarnowski, Matthew P Conomos, Ramachandran S Vasan, James B Meigs, Josée Dupuis, Ching-Ti Liu, Aaron Leong
Faculty, Staff and Student Publications
BACKGROUND: Whether genetics contribute to the rising prevalence of obesity or its cardiovascular consequences in today's obesogenic environment remains unclear. We sought to determine whether the effects of a higher aggregate genetic burden of obesity risk on body mass index (BMI) or cardiovascular disease (CVD) differed by birth year.
METHODS: We split the FHS (Framingham Heart Study) into 4 equally sized birth cohorts (birth year before 1932, 1932 to 1946, 1947 to 1959, and after 1960). We modeled a genetic predisposition to obesity using an additive genetic risk score (GRS) of 941 BMI-associated variants and tested for GRS-birth year interaction …
Dual Beam-Current Transformer Design For Monitoring And Reporting Of Electron Ultra-High Dose Rate (Flash) Beam Parameters, Kevin Liu, Allison Palmiero, Nitish Chopra, Brett Velasquez, Ziyi Li, Sam Beddar, Emil Schüler
Dual Beam-Current Transformer Design For Monitoring And Reporting Of Electron Ultra-High Dose Rate (Flash) Beam Parameters, Kevin Liu, Allison Palmiero, Nitish Chopra, Brett Velasquez, Ziyi Li, Sam Beddar, Emil Schüler
Faculty, Staff and Student Publications
PURPOSE: To investigate the usefulness and effectiveness of a dual beam-current transformer (BCTs) design to monitor and record the beam dosimetry output and energy of pulsed electron FLASH (eFLASH) beams in real-time, and to inform on the usefulness of this design for future eFLASH beam control.
METHODS: Two BCTs are integrated into the head of a FLASH Mobetron system, one located after the primary scattering foil and the other downstream of the secondary scattering foil. The response of the BCTs was evaluated individually to monitor beam output as a function of dose, scattering conditions, and ability to capture physical beam …
Risks Of Mortality And Severe Coronavirus Disease 19 (Covid-19) Outcomes In Patients With Or Without Systemic Lupus Erythematosus, Sebastian Bruera, Xiudong Lei, Hui Zhao, Jinoos Yazdany, Mariana Chavez-Macgregor, Sharon H Giordano, Maria E Suarez-Almazor
Risks Of Mortality And Severe Coronavirus Disease 19 (Covid-19) Outcomes In Patients With Or Without Systemic Lupus Erythematosus, Sebastian Bruera, Xiudong Lei, Hui Zhao, Jinoos Yazdany, Mariana Chavez-Macgregor, Sharon H Giordano, Maria E Suarez-Almazor
Faculty, Staff and Student Publications
OBJECTIVES: We compared the outcomes of patients with or without systemic lupus erythematosus (SLE) who were diagnosed with coronavirus disease 19 (COVID-19) and evaluated factors within patients with SLE associated with severe outcomes.
METHODS: This retrospective cohort study used the deidentified Optum COVID-19 electronic health record dataset to identify patients with COVID-19 from 1/1/2020 to 31/12/2020. Cases with SLE were matched with general controls at a ratio of 1:10 by age, sex, race and ethnicity and COVID-19 diagnosis date. Outcomes included 30-day mortality, mechanical ventilation, hospitalisation and intensive care unit admission. We evaluated the relationship between COVID-19-related outcomes and SLE …
Pd-L1 Translocation To The Plasma Membrane Enables Tumor Immune Evasion Through Mib2 Ubiquitination, Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H Young, Yong Li
Pd-L1 Translocation To The Plasma Membrane Enables Tumor Immune Evasion Through Mib2 Ubiquitination, Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H Young, Yong Li
Faculty, Staff and Students Publications
Programmed death-ligand 1 (PD-L1), a critical immune checkpoint ligand, is a transmembrane protein synthesized in the endoplasmic reticulum of tumor cells and transported to the plasma membrane to interact with programmed death 1 (PD-1) expressed on T cell surface. This interaction delivers coinhibitory signals to T cells, thereby suppressing their function and allowing evasion of antitumor immunity. Most companion or complementary diagnostic devices for assessing PD-L1 expression levels in tumor cells used in the clinic or in clinical trials require membranous staining. However, the mechanism driving PD-L1 translocation to the plasma membrane after de novo synthesis is poorly understood. Herein, …
Sumoylation Regulates Functional Properties Of The Oocyte Transcription Factors Sohlh1 And Nobox, Bethany K Patton, Surabhi Madadi, Shawn M Briley, Avery A Ahmed, Stephanie A Pangas
Sumoylation Regulates Functional Properties Of The Oocyte Transcription Factors Sohlh1 And Nobox, Bethany K Patton, Surabhi Madadi, Shawn M Briley, Avery A Ahmed, Stephanie A Pangas
Faculty, Staff and Students Publications
SOHLH1 and NOBOX are oocyte-expressed transcription factors with critical roles in ovary development and fertility. In mice, Sohlh1 and Nobox are essential for fertility through their regulation of the oocyte transcriptional network and cross-talk to somatic cells. Sumoylation is a posttranslational modification that regulates transcription factor function, and we previously showed that mouse oocytes deficient for sumoylation had an altered transcriptional landscape that included significant changes in NOBOX target genes. Here, we show that mouse SOHLH1 is modified by SUMO2/3 at lysine 345 and mutation of this residue alters SOHLH1 nuclear to cytoplasmic localization. In NOBOX, we identify a non-consensus …
Comparison Of Percentile Tables And Algorithm-Based Calculators For Classification Of Blood Pressures In Children And Adolescents With Obesity: A Secondary Analysis Of A Clinical Trial, William J Pitts, Tami L Cave, Alana Cavadino, Roman J Shypailo, Sarah E Maessen, Paul L Hofman, William Wong, Yvonne C Anderson
Comparison Of Percentile Tables And Algorithm-Based Calculators For Classification Of Blood Pressures In Children And Adolescents With Obesity: A Secondary Analysis Of A Clinical Trial, William J Pitts, Tami L Cave, Alana Cavadino, Roman J Shypailo, Sarah E Maessen, Paul L Hofman, William Wong, Yvonne C Anderson
Faculty, Staff and Students Publications
AIM: Obesity as a major risk factor for childhood hypertension necessitates careful blood pressure (BP) monitoring of those affected. This study aimed to compare BP classification in a cohort of children affected by obesity using tables versus digital calculations in two sets of guidelines.
METHODS: This study was a secondary analysis of data collected from a randomised clinical trial of a multidisciplinary life-style assessment and intervention program. Baseline data from 237 children with a body mass index >99th percentile or >91st percentile with weight-related comorbidities and available BP measurements were analysed. We assessed agreement between tables and algorithms in classification …
The Nlrp3 Inflammasome Fires Up Heme-Induced Inflammation In Hemolytic Conditions, Suruchi Salgar, Beatriz E Bolívar, Jonathan M Flanagan, Shaniqua J Anum, Lisa Bouchier-Hayes
The Nlrp3 Inflammasome Fires Up Heme-Induced Inflammation In Hemolytic Conditions, Suruchi Salgar, Beatriz E Bolívar, Jonathan M Flanagan, Shaniqua J Anum, Lisa Bouchier-Hayes
Faculty, Staff and Students Publications
Overactive inflammatory responses are central to the pathophysiology of many hemolytic conditions including sickle cell disease. Excessive hemolysis leads to elevated serum levels of heme due to saturation of heme scavenging mechanisms. Extracellular heme has been shown to activate the NLRP3 inflammasome, leading to activation of caspase-1 and release of pro-inflammatory cytokines IL-1β and IL-18. Heme also activates the non-canonical inflammasome pathway, which may contribute to NLRP3 inflammasome formation and leads to pyroptosis, a type of inflammatory cell death. Some clinical studies indicate there is a benefit to blocking the NLRP3 inflammasome pathway in patients with sickle cell disease and …
Differential Strain-Dependent Ovarian And Metabolic Responses In A Mouse Model Of Pcos, April K. Binder, Danielle L. Peecher, Amanda J. Qvigstad, Silvia D. Gutierrez, Jennifer Magaña, David B. Banks, Kenneth S. Korach
Differential Strain-Dependent Ovarian And Metabolic Responses In A Mouse Model Of Pcos, April K. Binder, Danielle L. Peecher, Amanda J. Qvigstad, Silvia D. Gutierrez, Jennifer Magaña, David B. Banks, Kenneth S. Korach
Biology Faculty Scholarship
Several mouse models have been developed to study polycystic ovarian syndrome (PCOS), a leading cause of infertility in women. Treatment of mice with dihydrotestosterone (DHT) for 90-days causes ovarian and metabolic phenotypes similar to women with PCOS. We used this 90-day DHT treatment paradigm to investigate the variable incidence and heterogeneity in two inbred mouse strains, NOD/ShiLtJ and 129S1/SvlmJ. NOD mice naturally develop type 1 diabetes, and recent meta-analysis found increased androgen excess and PCOS in women with type 1 diabetes. 129S1 mice are commonly used in genetic manipulations. Both NOD and 129S1 DHT treated mice had early vaginal opening, …
Association Between Covid-19 And Postoperative Neurological Complications And Antipsychotic Medication Use After Cancer Surgery: A Retrospective Study, Juan P Cata, Jian Hu, Lei Feng, Caroline Chung, Scott E Woodman, Larissa A Meyer
Association Between Covid-19 And Postoperative Neurological Complications And Antipsychotic Medication Use After Cancer Surgery: A Retrospective Study, Juan P Cata, Jian Hu, Lei Feng, Caroline Chung, Scott E Woodman, Larissa A Meyer
Faculty, Staff and Student Publications
Introduction: Millions of Americans infected with the severe acute respiratory syndrome-associated coronavirus-19 (COVID-19) need oncologic surgery. Patients with acute or resolved COVID-19 illness complain of neuropsychiatric symptoms. How surgery affects postoperative neuropsychiatric outcomes such as delirium is unknown. We hypothesize that patients with a history of COVID-19 could have an exaggerated risk of developing postoperative delirium after undergoing major elective oncologic surgery.
Methods: We conducted a retrospective study to determine the association between COVID-19 status and antipsychotic drugs during postsurgical hospitalization as a surrogate of delirium. Secondary outcomes included 30 days of postoperative complications, length of stay, and mortality. Patients …
Autonomic Function Recovery And Physical Activity Levels In Post-Covid-19 Young Adults After Immunization: An Observational Follow-Up Case-Control Study, Ana Paula Coelho Figueira Freire, Shaan Amin, Fabio Santos Lira, Ana Elisa Von Ah Morano, Telmo Pereira, Manuel-João Coelho-E-Silva, Armando Caseiro, Diego Giulliano Destro Christofaro, Vanessa Ribeiro Dos Santos, Osmar Marchioto Júnior, Ricardo Aurino Pinho, Bruna Spolador De Alencar Silva
Autonomic Function Recovery And Physical Activity Levels In Post-Covid-19 Young Adults After Immunization: An Observational Follow-Up Case-Control Study, Ana Paula Coelho Figueira Freire, Shaan Amin, Fabio Santos Lira, Ana Elisa Von Ah Morano, Telmo Pereira, Manuel-João Coelho-E-Silva, Armando Caseiro, Diego Giulliano Destro Christofaro, Vanessa Ribeiro Dos Santos, Osmar Marchioto Júnior, Ricardo Aurino Pinho, Bruna Spolador De Alencar Silva
All Faculty Scholarship for the College of Education and Professional Studies
Coronavirus disease 2019 (COVID-19) has detrimental multi-system consequences. Symptoms may appear during the acute phase of infection, but the literature on long-term recovery of young adults after mild to moderate infection is lacking. Heart rate variability (HRV) allows for the observation of autonomic nervous system (ANS) modulation post-SARS-CoV-2 infection. Since physical activity (PA) can help improve ANS modulation, investigating factors that can influence HRV outcomes after COVID-19 is essential to advancements in care and intervention strategies. Clinicians may use this research to aid in the development of non-medication interventions. At baseline, 18 control (CT) and 20 post-COVID-19 (PCOV) participants were …
4d Lung Mri With High-Isotropic-Resolution Using Half-Spoke (Ute) And Full-Spoke 3d Radial Acquisition And Temporal Compressed Sensing Reconstruction, Can Wu, Guruprasad Krishnamoorthy, Victoria Yu, Ergys Subashi, Andreas Rimner, Ricardo Otazo
4d Lung Mri With High-Isotropic-Resolution Using Half-Spoke (Ute) And Full-Spoke 3d Radial Acquisition And Temporal Compressed Sensing Reconstruction, Can Wu, Guruprasad Krishnamoorthy, Victoria Yu, Ergys Subashi, Andreas Rimner, Ricardo Otazo
Faculty, Staff and Student Publications
Objective:
To develop a respiratory motion-resolved 4D MRI technique with high-isotropic-resolution (1.1 mm) using 3D radial sampling, camera-based respiratory motion sensing, and temporal compressed sensing reconstruction for lung cancer imaging.
Approach:
Free-breathing half- and full-spoke 3D golden-angle radial acquisitions were performed on eight healthy volunteers and eight patients with lung tumors of varying size. A back-and-forth k-space ordering between consecutive interleaves of the 3D radial acquisition was performed to minimize eddy current-related artifacts. Data were sorted into respiratory motion states using camera-based motion navigation and 4D images were reconstructed using temporal compressed sensing to reduce scan time. Normalized sharpness indices …