Public Health Commons^™

Monte Carlo-Derived 99m Tc Uptake Quantification With Commercial Planar Mbi: Tumor And Breast Activity Concentrations, Benjamin P Lopez, S Cheenu Kappadath

Faculty, Staff and Student Publications

BACKGROUND: Current molecular breast imaging (MBI) images are limited to qualitative evaluation, not absolute measurement, of

PURPOSE: This work assesses the accuracy of previously-published and newly-proposed tumor and normal breast tissue

METHODS: Quantification techniques were tested in over 4000 simulated acquisitions of spherical and ellipsoid tumors with clinically relevant uptake conditions using a validated Monte Carlo application of the GE Discovery NM750b system. The evaluated techniques consisted of four tumor total activity methodologies (two single-detector-based and two geometric-mean-based), two tumor MBI volume methodologies (diameter-based and ROI-based), and two normal tissue activity concentration methodologies (single-detector-based and geometric-mean-based). The most accurate of …

Intensity Modulated Proton Arc Therapy Via Geometry-Based Energy Selection For Ependymoma, Wenhua Cao, Yupeng Li, Xiaodong Zhang, Falk Poenisch, Pablo Yepes, Narayan Sahoo, David Grosshans, Susan Mcgovern, G Brandon Gunn, Steven J Frank, Xiaorong R Zhu

Faculty, Staff and Student Publications

PURPOSE: We developed and tested a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources similar to those for regular intensity-modulated proton therapy (IMPT) plans and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries.

METHODS: Our IMPAT planning method consists of a geometry-based energy selection step with major scanning spot contributions as inputs computed using ray-tracing and single-Gaussian approximation of lateral spot profiles. Based on the geometric relation of scanning spots and dose voxels, our energy selection module selects a minimum set of energy layers at each gantry angle …

Vincristine/Irinotecan/Temsirolimus Upfront Window Treatment Of High-Risk Hepatoblastoma: A Report From The Children’S Oncology Group Ahep0731 Study Committee, Patrick A Thompson, Marcio H Malogolowkin, Wayne L Furman, Jin Piao, Mark D Krailo, Nadia Chung, Lindsay Brock, Alexander J Towbin, Elizabeth B Mccarville, Milton J Finegold, Sarangarajan Ranganathan, Stephen P Dunn, Max R Langham, Eugene D Mcgahren, Gregory M Tiao, Christopher B Weldon, Allison F O'Neill, Carlos Rodriguez-Galindo, Rebecka L Meyers, Howard M Katzenstein

Faculty, Staff and Students Publications

Background: Survival for children with metastatic hepatoblastoma (HB) remains suboptimal. We report the response rate and outcome of two courses of vincristine/irinotecan/temsirolimus (VIT) in children with high-risk (HR)/metastatic HB.

Procedures: Patients with newly diagnosed HB received HR window chemotherapy if they had metastatic disease or a serum alpha-fetoprotein (AFP) level less than 100 ng/mL. Patients received vincristine (days 1 and 8), irinotecan (days 1-5), and temsirolimus (days 1 and 8). Cycles were repeated every 21 days. Responders had either a 30% decrease using RECIST (Response Evaluation Criteria in Solid Tumors) criteria OR a 90% (>1 log10 decline) AFP decline …

Longitudinal Analysis Of The Evolution Of Cellular Immunity To Sars-Cov-2 Induced By Infection And Vaccination, Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M Rooney, Ann M Leen

Faculty, Staff and Students Publications

No abstract provided.

Prematurity Blunts Protein Synthesis In Skeletal Muscle Independently Of Body Weight In Neonatal Pigs, Marko Rudar, Jane K Naberhuis, Agus Suryawan, Hanh V Nguyen, Marta L Fiorotto, Teresa A Davis

Faculty, Staff and Students Publications

Background

Postnatal growth failure in premature infants is associated with reduced lean mass accretion. Prematurity impairs the feeding-induced stimulation of translation initiation and protein synthesis in the skeletal muscle of neonatal pigs. The objective was to determine whether body weight independently contributes to the blunted postprandial protein synthesis.

Methods

Preterm and term pigs that were either fasted or fed were stratified into quartiles according to birth weight to yield preterm and term groups of similar body weight; first and second quartiles of preterm pigs and third and fourth quartiles of term pigs were compared (preterm-fasted, n = 23; preterm-fed, n …

Neurocomputing And Interfacing Digital Tasting System: Research, Design, And Evaluation, Amira J. Zaylaa, Ahmad El Hajj

BAU Journal - Science and Technology

The continuous evolution in computing and interfacing has been extended to develop multi-sensory experiences in many domains such as neurological, auditory, vision, and haptic domains. So far, only a few remarkable system approaches have been approved to be serving the taste sensation digitally. Although taste sensation is linked to the brain, there is a lack of optimal neurocomputing digital taste sensation systems. Our study provides a new neurocomputing method to digitally stimulate the sense of taste by electrical stimulation on the human tongue. We aim to link chemical stimulation and electrical stimulation in order to design an electronic interface for …

Prevalence And Burden Of Gastrointestinal Parasites Among University Students At Dar Es Salaam University College Of Education, Tanzania, Magreth Fulgence, Ummul-Khair Mustafa, Jared S. Bakuza

Tanzania Journal of Science

Gastrointestinal parasites cause major health problems in many tropical and sub-tropical countries including Tanzania. However, information on the status of these infections is often scanty, especially among young adults including students in higher learning institutions.  During December 2020 to June 2021, a total of 272 faecal samples from university students at Dar es Salaam University College of Education (DUCE) were examined for parasites using the Kato Katz technique and analysed for infection levels based on standard guidelines. Detected parasites were identified as Schistosoma mansoni (8.1%), hookworms (1.5%), Trichuris trichiura (0.4%) and Hymenolepis diminuta (0.4%), with an overall prevalence of 10.4%. …

Assessment Of Antimicrobial Competence Of Epiphytes And Endophytes From Osmium Basilicum And Trigonella Foenum Graecum, Iram Asim, Atia Iqbal, Muhammad Ikrama Tanveer

Journal of Bioresource Management

Plant-associated bacteria are an unexplored group of microorganisms that has enormous potential. These bacteria are the source of finding new antimicrobial substances. The present study aimed to isolate and characterize the epiphytes and endophytes from Osmium basilicum and Trigonella foenum graecum plants and to determine their antimicrobial potential against pathogenic bacteria from Nishtar Hospital Multan, Pakistan. The sum of 18 stems and roots along leaf specimens were assembled as of the plant's Osmium basilicum plus Trigonella foenum graecum as of the distinct locales of the Multan city. Overall 73 bacterial strains were isolated and their colony morphology, gram staining, spore …

Monitoring Personal Exposure To Air Quality Gradients While Biking On An Elevated Urban Trail, Gavin D. Salas

DePaul Discoveries

Air pollution is a major global health concern, specifically as it relates to the human exposome. The EPA criteria pollutants, including particulate matter (PM), carbon monoxide (CO), carbon dioxide (CO₂), and NO_x can have severe impacts on respiratory and cardiovascular health, particularly in populations with chronic illnesses such as asthma, those facing economic hardships and individuals who frequently spend time outdoors, such as bicyclists and runners. To understand the impact of air pollution on human health, it is essential to assess personal exposure. This study aimed to investigate personal exposure to air pollution levels while biking along …

Creating And Activating An Implementation Community To Drive Hpv Vaccine Uptake In Texas: The Role Of An Nci-Designated Cancer Center, Rosalind S Bello, Michael T Walsh, Blake Harper, Charles E Amos, Katherine Oestman, Stephanie Nutt, Marcita Galindez, Kaitlyn Block, Ruth Rechis, Erica M Bednar, Jennifer Tektiridis, Lewis Foxhall, Mark Moreno, Sanjay Shete, Ernest Hawk

Faculty, Staff and Student Publications

The University of Texas MD Anderson Cancer Center, a comprehensive cancer center designated by the National Cancer Institute (NCI), defines its service population area as the State of Texas (29.1 M), the second most populous state in the country and the state with the greatest number of uninsured residents in the United States. Consistent with a novel and formal commitment to prevention as part of its core mission, alongside clear opportunities in Texas to drive vaccine uptake, MD Anderson assembled a transdisciplinary team to develop an institutional Framework to increase adolescent HPV vaccination and reduce HPV-related cancer burden. The Framework …

Closing Racial Disparity By Dismantling Constructs Of Fear - A Practical Methodology For Learning To Swim, Dane W. Wolfrom, Christine L. Snellgrove, Marisol A. Rivera, Keisha Laguer Vandessppooll, Emily D. Feliciano

International Journal of Aquatic Research and Education

African American, Black, Hispanic, Latino, and low-socioeconomic communities have lower swimming ability and higher relative drowning rates than White and high-socioeconomic communities, distinguishing the former as high-priority populations to engage with effective learn-to-swim programming. This article demonstrates how prioritizing the reduction of fear-producing brain processes while learning to swim can result in 79.5% of high-priority population non-swimmers being able to jump into deep water, roll onto their backs and either float or tread for 60 seconds, and swim 25 yards after an average of 14 practice sessions. Practical explanations of four key components— water exploration, structured games, emulating coaches, and …

Racist Or Radical? The Strange Case Of Robert Moses And The Building Of New York City's Aquatics Infrastructure, Steven N. Waller Ph.D., James H. Bemiller J.D., Jason L. Scott Ph.D.

International Journal of Aquatic Research and Education

Who was Robert Moses? In this article, we want to cast a bright light on Robert Moses as a visionary urban planner, which included the comprehensive planning of the outdoor and indoor aquatic infrastructure for New York City. Second, we want to highlight some of his administration's significant accomplishments and challenges in providing aquatics opportunities for diverse populations, including people of color. Finally, we aspire to illustrate what happens when officials with power and authority in local government are permitted to operate without scrutiny and are unbeholden to a meaningful series of checks and balances. Robert Moses’ tenure as a …

A Leisure Model: Barriers And Black Womxn Collegiate Swimmers, Tiffany Monique Quash

International Journal of Aquatic Research and Education

There remains a gap in the literature about the experiences of Black Womxn Collegiate Swimmers (hereafter referred to as BWCS) and the application of the leisure constraints model. Whether research has been conducted with Black Womxn Swimmers enrolled in a swimming course while using an autoethnographic lens (Norwood, 2010) or the representation of one Black Womxn Swimmer from a Predominantly White Institution (Quash, 2018), minimal knowledge is known about this specific demographic representative of Historically Black Colleges and Universities (HBCUs) and Predominantly White Institutions (PWIs) and the barriers they experience. Using a qualitative methodological approach to understand the leisure constraints …

Third Diversity In Aquatics Special Issue, Angela K. Beale-Tawfeeq, Steven N. Waller Ph.D., Tiffany M. Quash Phd

International Journal of Aquatic Research and Education

Front matter - none available

“Pool: A Social History Of Segregation Exhibition” Exploring Social Justice Through The Lens Of Water Safety Awareness And Art-Based Education, Angela K. Beale-Tawfeeq Ph.D., Mph, Tiffany Monique Quash Ph.D., Knolan Rawlins Ph.D., Victoria Prizzia, Miriam Lynch Ph.D.

International Journal of Aquatic Research and Education

Art exhibitions, with a focus on water safety and drowning prevention, are rarely seen as a medium to address social justice and public health, or water safety awareness and drowning prevention efforts in communities. Globally, data have shown drowning is considered a “neglected public health threat” (World Health Organization, 2021, CDC, 2023). Additionally, reports have shown that across the globe there are demographic groups of people impacted by drowning, historical traumas, and social determinants, also impacting some communities that are at greater risk (WHO 2021, CDC, 2023). Although there are national and international efforts to address the importance of water …

Blue-Mindfulness Training: A Story Of Restorative Justice Decolonizing And Re-Indigenizing Communal Relationships With Water, Thaddeus Gamory, Miriam Lynch Ph.D., A. Udaya Thomas, Angela K. Beale-Tawfeeq Ph.D., Mph

International Journal of Aquatic Research and Education

This article aims to introduce and describe the development of the concept of Blue-Mindfulness Training^TM, which was created and designed by Thaddeus Gamory and supported by research and the experience of other experts in the field. Drawing from the author’s and others' practical experience, the authors present a "Voice from the Field" perspective on creating and developing the Blue-Mindfulness^TM . This Instructional Framework, coined by Mr. Thaddeus Gamory Blue-Mindfulness^TM, addresses the impacts of historical racial discrimination and trauma in BIPOC communities, specifically on marginalized African American communities while promoting a communal and safe relationship with …

Self-Reported Water Competency Skills At A Historically Black College & University And The Potential Impact Of Additional Hbcu-Based Aquatic Programming, Knolan C. Rawlins Ph.D., Shaun M. Anderson Ed.D, Tiffany Monique Quash Ph.D.

International Journal of Aquatic Research and Education

This article provides an analysis of self-reported water competency skills at a Historically Black University (HBCU). A survey was administered to undergraduate students who lived on campus at one HBCU. Of the 254 respondents that reported the ability to swim, only 187 respondents self-reported the ability to swim and the ability to perform water competency skills. The biggest discrepancy occurred within individuals that identified as Black or African American. In this group, 142 out of 250 participants proclaimed the ability to swim. However, the number of Black or African Americans that could swim dropped to 84 when researchers operationally defined …

Let Kids Sleep: The Role Of Interdisciplinary Neuroscience Outreach In Stimulating Brains And Developing Research-Informed Approaches To Community Concerns, Marc Chenard

University Honors Theses

Northwest Noggin (NW Noggin), an all-volunteer neuroscience education outreach non-profit, serves its community by bringing students, artists, scientists and other participants together for artistic collaboration and learning. The outreach takes place in K-12 schools and other institutions (such as museums, coffee shops and correctional facilities) all over the Pacific Northwest. Neuroscience education outreach generates discourse surrounding community concerns through illuminating the brain-centric qualities of issues and by drawing on neuroscience research to create solutions. The neuroscience research-informed perspectives on these concerns stimulate awareness, create momentum towards evidence-based reform, and can result in policy interventions. This thesis details how NW Noggin …

Dietary Sources Of Linoleic Acid (La) Differ By Race/Ethnicity In Adults Participating In The National Health And Nutrition Examination Survey (Nhanes) Between 2017-2018, Shabnam R Momin, Mackenzie K Senn, Ani Manichaikul, Chaojie Yang, Rasika Mathias, Mimi Phan, Stephen S Rich, Susan Sergeant, Michael Seeds, Lindsay Reynolds, Floyd H Chilton, Alexis C Wood

Faculty, Staff and Students Publications

Linoleic acid (LA) is a primary n-6 polyunsaturated fatty acid (PUFA), which is of interest to nutritional professionals as it has been associated with health outcomes. However, as some LA-rich foods offer protection against chronic diseases such as CVD (e.g., fatty fish), while others increase risk (e.g., red meat), the individual foods contributing to LA intake may be an important factor to consider. Therefore, this analysis sought to examine whether there are racial/ethnic differences in the proportion of overall LA intake accounted for by individual food groups, via a cross-sectional analysis of 3815 adults participating in the National Health …

Social Risks, Social Needs, And Attitudes Toward Social Health Screening 1 Year Into The Covid-19 Pandemic: Survey Of Adults In An Integrated Health Care Delivery System, Nancy P Gordon, Carmen Byker Shanks, Richard W Grant

Faculty, Staff and Student Publications

Introduction Information about demographic differences in social risks, needs, and attitudes toward social health screening in non-highly vulnerable adult populations is lacking. Methods The authors analyzed data for 2869 Kaiser Permanente Northern California non-Medicaid-covered members aged 35 to 85 who responded to a 2021 English-only mailed/online survey. The survey covered 7 social risk and 11 social needs domains and attitudes toward social health screening. The authors used data weighted to the Kaiser Permanente Northern California membership to estimate prevalence of risks, needs, and screening receptivity in the overall population, by race/ethnicity (White, Black, Latinx, Asian American/Pacific Islander) and age (35-65 …

Effect Of Fenugreek And Curry Leaves Powder On Dyslipidemia- A Randomized Controlled Pilot Study, Syeda Farha S, Shivani Agarwal, Vanitha Reddy P

International Journal of Health and Allied Sciences

Background: Dyslipidemias, a disorder of lipid metabolism, is widely established as an independent major and modifiable risk factor of cardiovascular disease (CVD). The conditions are common worldwide and a leading cause of death in India, and has even riven the age bar swaying in young people too. The significant effect of an increase in dyslipidemias depends on diabetes and hypertension. Nutraceuticals, derived from food sources serve as an alternative therapy for the management of dyslipidemia. India is home to multitudinous medicinal plants, of which many remain underutilized. Murraya Koenigii (curry leaf) and Trigonella foenum-graecum (fenugreek leaves) are well-proven as good …

Healthy Eating Interventions Delivered In Early Childhood Education And Care Settings For Improving The Diet Of Children Aged Six Months To Six Years, Sze Lin Yoong, Melanie Lum, Luke Wolfenden, Jacklyn Jackson, Courtney Barnes, Alix E. Hall, Sam Mccrabb, Nicole Pearson, Cassandra Lane, Jannah Z. Jones, Lauren Dinour, Therese Mcdonnell, Debbie Booth, Alice Grady

Department of Nutrition and Food Studies Scholarship and Creative Works

Background

Dietary intake during early childhood can have implications on child health and developmental trajectories. Early childhood education and care (ECEC) services are recommended settings to deliver healthy eating interventions as they provide access to many children during this important period. Healthy eating interventions delivered in ECEC settings can include strategies targeting the curriculum (e.g. nutrition education), ethos and environment (e.g. menu modification) and partnerships (e.g. workshops for families). Despite guidelines supporting the delivery of healthy eating interventions in this setting, little is known about their impact on child health.

Objectives

To assess the effectiveness of healthy eating interventions delivered …

Diet Quality Among Pre-Adolescent African American Girls In A Randomized Controlled Obesity Prevention Intervention Trial, Debbe Thompson, Yiming Mirabile, Noemi Islam, Chishinga Callender, Salma M A Musaad, Julie Miranda, Jennette P Moreno, Jayna M Dave, Tom Baranowski

Faculty, Staff and Students Publications

Consuming an unhealthy diet increases health risks. This study assessed the impact of a culturally adapted behaviorally innovative obesity prevention intervention (The Butterfly Girls and the Quest for Founder’s Rock) on diet quality in pre-adolescent non-Hispanic Black/African American girls. The RCT consisted of three groups (experimental, comparison, and waitlist control); block randomization allocated participants to each group. The two treatment groups varied in terms of whether or not they set goals. Data were collected at baseline (prior to receiving the intervention), post 1 (3 months post-baseline), and post 2 (6 months post-baseline). Two dietitian-assisted 24 h dietary recalls …

Parabens Promote Protumorigenic Effects In Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry, Jazma L. Tapia, Jillian C. Mcdonough, Emily L. Cauble, Cesar G. Gonzalez, Dede K. Teteh, Lindsey S. Treviño

Health Sciences and Kinesiology Faculty Articles

Context

One in 8 women will develop breast cancer in their lifetime. Yet, the burden of disease is greater in Black women. Black women have a 40% higher mortality rate than White women, and a higher incidence of breast cancer at age 40 and younger. While the underlying cause of this disparity is multifactorial, exposure to endocrine disrupting chemicals (EDCs) in hair and other personal care products has been associated with an increased risk of breast cancer. Parabens are known EDCs that are commonly used as preservatives in hair and other personal care products, and Black women are disproportionately exposed …

Factors Associated With Food Choice Motivations Among Urban High School Students In Indonesia, Syarifah Aqilah, Anuchit Phanumartwiwath, Nutta Taneepanichskul

Journal of Health Research

Background: This study aimed to examine what reasons motivated urban high school students to choose certain foods, and to identify factors associated with food choice motivations.

Methods: A cross-sectional study was conducted from April to May 2020 in Depok, Indonesia. A total of 433 high school students in grades 10–12 were recruited. Food choice motivations were identified using a questionnaire, and defined using exploratory factor analysis. Possible factors associated with motivations were evaluated using multiple linear regression.

Results: Five food choice motivations were identified and classed as: F1, health and religion; F2, price and convenience; F3, comfort; F4, weight control; …

A Nurse-Led Telehealth Program For Diabetes Foot Care: Feasibility And Usability Study, Hsiao-Hui Ju, Rashmi Momin, Stanley Cron, Jed Jularbal, Jeffery Alford, Constance Johnson

Faculty, Staff and Student Publications

BACKGROUND: Diabetes mellitus can lead to severe and debilitating foot complications, such as infections, ulcerations, and amputations. Despite substantial progress in diabetes care, foot disease remains a major challenge in managing this chronic condition that causes serious health complications worldwide.

OBJECTIVE: The primary aim of this study was to examine the feasibility and usability of a telehealth program focused on preventive diabetes foot care. A secondary aim was to descriptively measure self-reported changes in diabetes knowledge, self-care, and foot care behaviors before and after participating in the program.

METHODS: The study used a single-arm, pre-post design in 2 large family …

Improving Microbiome Research Through Enhanced Reporting And Modeling The Effects Of Antibiotic Usage, Chloe A. Mirzayi

Dissertations and Theses

I consider two key areas in the growing field of human microbiome research: improving the quality of study reporting and the impact of antibiotics on participants in human gut microbiome research studies. In the first chapter, a team of evaluators used the Strengthening the Organization and Reporting of Microbiome Studies (STORMS) checklist to assess recently published microbiome literature. I found moderate agreement and reliability between evaluators, identified several items in STORMS that could be improved, and confirmed that the STORMS checklist can serve as a tool for assessing the reporting quality of published microbiome study. The next chapter considers pre-exposure …

Digital Health Technologies For Peripartum Depression Management Among Low-Socioeconomic Populations: Perspectives From Patients, Providers, And Social Media Channels, Alexandra Zingg, Tavleen Singh, Amy Franklin, Angela Ross, Sudhakar Selvaraj, Jerrie Refuerzo, Sahiti Myneni

Faculty, Staff and Student Publications

BACKGROUND: Peripartum Depression (PPD) affects approximately 10-15% of perinatal women in the U.S., with those of low socioeconomic status (low-SES) more likely to develop symptoms. Multilevel treatment barriers including social stigma and not having appropriate access to mental health resources have played a major role in PPD-related disparities. Emerging advances in digital technologies and analytics provide opportunities to identify and address access barriers, knowledge gaps, and engagement issues. However, most market solutions for PPD prevention and management are produced generically without considering the specialized needs of low-SES populations. In this study, we examine and portray the information and technology needs …

Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, Jiongming Wang, Elena Feofanova, Joshua C Bis, Kerri L Wiggins, Jennifer E Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L Kinney, Jennifer A Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, Joann E Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C Charles Gu, Donald M Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M Psaty, Donna K Arnett, Carmen R Isasi, Stephen S Rich, Robert C Kaplan, Susan Redline, Braxton D Mitchell, Nora Franceschini, Daniel Levy, Jerome I Rotter, Alanna C Morrison, Tamar Sofer

Faculty, Staff and Student Publications

We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare "clumping-and-thresholding" (PRSice2) and LD-based (LDPred2) methods to construct PRSs from each of multiple GWAS, as well as multi-PRS approaches that sum PRSs with and without weights, including PRS-CSx. We use datasets from the MGB Biobank, TOPMed study, UK biobank, and from All of Us to train, assess, and validate PRSs in groups defined by self-reported race/ethnic background (Asian, Black, Hispanic/Latino, and White). For both SBP and DBP, the PRS-CSx based PRS, constructed as a weighted sum of PRSs …

(R2032) Modeling The Effect Of Sanitation Effort On The Spread Of Carrier-Dependent Infectious Diseases Due To Environmental Degradation, Ram Naresh, Sandhya Rani Verma, J. B. Shukla, Manju Agarwal

Applications and Applied Mathematics: An International Journal (AAM)

In this present study, an SIS model is proposed and analyzed to study the effect of sanitation effort in controlling the spread of carrier-dependent infectious disease in a human habitat due to environmental degradation. The dynamics of the model consist of six dependent variables, the susceptible population density, infective population density, carrier population density, cumulative density of environmental degradation and the density of sanitation effort applied on carrier population and degraded environment. In the modeling process, the carrier population density and sanitation effort are modeled logistically and the degradation of the environment is assumed to be directly proportional to the …