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Full-Text Articles in Public Health

Observational Analysis For Predicting Initial Spikes In Testing Volume Of Cohorts Inside And Outside Of A Regional Covid-19 Screening Program, Adam M. Franks, Seth Bergeron, Tammy Bannister, Justin Spradling, Tamara Lowe, Paris Johnson, Rajan Lamichhane, Stephen M. Petrany Apr 2024

Observational Analysis For Predicting Initial Spikes In Testing Volume Of Cohorts Inside And Outside Of A Regional Covid-19 Screening Program, Adam M. Franks, Seth Bergeron, Tammy Bannister, Justin Spradling, Tamara Lowe, Paris Johnson, Rajan Lamichhane, Stephen M. Petrany

Marshall Journal of Medicine

BACKGROUND Containing the highly contagious SARs-CoV-2 pathogen requires a safe and effective screening program. The aim of this observational cohort study is to analyze a regional testing center and identify factors predicting testing rates that direct supply and staffing needs.

METHODS A drive-through SAR-CoV-2 regional testing facility was created. Number of tests and positive results were collected for eighteen months. Data for testing demand was compared to positive results, percent positive rates (PPR), known external factors, and county PPR. Dissimilarities were contrasted with dynamic time warp and a detailed agreement analysis. The Grainger’s test was utilized to assess the degree …


Opioid-Related Emergency Department Visits Before And During Covid-19: Association With Community-Level Factors, Timothy F. Page, Weiwei Chen, François Sainfort, Julie A. Jacko Apr 2024

Opioid-Related Emergency Department Visits Before And During Covid-19: Association With Community-Level Factors, Timothy F. Page, Weiwei Chen, François Sainfort, Julie A. Jacko

HCA Healthcare Journal of Medicine

Background

The purpose of the study was to investigate the relationship between community-level variables and emergency department (ED) visit rates before and during COVID-19. The focus was on opioid-related ED visits. Despite large declines in overall ED visits during COVID-19, opioid-related visits increased. While visits for avoidable conditions decreased, the opposite was true for opioid-related visits.

Methods

We combined data from Florida EDs with community-level variables from the 2020 American Community Survey. The outcome measures of the study were quarterly ZIP code tabulation-area-level ED visit rates for opioid-related ED visits as well as visit rates for all other causes. Associations …


Ensuring Equitable Application Of Interventions To Vulnerable Subpopulations In The Kentucky Consortium For Accountable Health Communities (Kc-Ahc), Jing Li, Jessica M. Clouser, Akosua Adu, Aiko Weverka, Nikita Vundi, Terry D. Stratton, Mark V. Williams Apr 2024

Ensuring Equitable Application Of Interventions To Vulnerable Subpopulations In The Kentucky Consortium For Accountable Health Communities (Kc-Ahc), Jing Li, Jessica M. Clouser, Akosua Adu, Aiko Weverka, Nikita Vundi, Terry D. Stratton, Mark V. Williams

Journal of Appalachian Health

Introduction: The Centers for Medicare and Medicaid Services (CMS) has funded the Accountable Health Communities (AHC) model to test whether systematically identifying and addressing the health-related social needs (HRSNs) of individuals would impact healthcare utilization and total cost of care for Medicare and Medicaid beneficiaries. Toward this effort, AHCs implement screening, referral, and community navigation services in their local areas. There are 28 CMS-funded AHCs nationwide, including the Kentucky Consortium for Accountable Health Communities (KC-AHC).

Purpsoe: This study aims to assess the equity of KC-AHC model activities in three vulnerable sub-populations: dual enrollees, disabled individuals, and women.

Methods: Twenty-eight primary …


Factors Predicting Work Ability Among Community Healthcare Providers In Yangon, Myanmar, Phyu Nyein Wai, Naw Clara Apr 2024

Factors Predicting Work Ability Among Community Healthcare Providers In Yangon, Myanmar, Phyu Nyein Wai, Naw Clara

Makara Journal of Health Research

Background: In healthcare organizations, a high level of work ability is necessary for workers to perform their tasks under different working conditions. This study aimed to describe the quality of work life, work environment, and work ability and examine predictors of the work ability of community healthcare providers.

Methods: A cross-sectional descriptive study was conducted from May 2020 to July 2020. The study enrolled 284 registered nurses and midwives from 38 public health departments in Yangon, Myanmar. Data were collected using the work-related quality of life scale (WRQoL) 2, work environment impact scale (WEIS-SR), and work ability index …


Perception Of Lean Adoption Among Emergency Department Personnel In Public Hospitals In Selangor, Malaysia, Azizul Rahman Mohamad Jamil, Mohd Rizal Abdul Manaf, Sharifa Ezat Wan Puteh, Kiran Ganesh Balakrishnan Apr 2024

Perception Of Lean Adoption Among Emergency Department Personnel In Public Hospitals In Selangor, Malaysia, Azizul Rahman Mohamad Jamil, Mohd Rizal Abdul Manaf, Sharifa Ezat Wan Puteh, Kiran Ganesh Balakrishnan

Makara Journal of Health Research

Background: This research aims to assess the perceptions of the staff working in emergency departments in Selangor, Malaysia, regarding the adoption of lean management and identify the factors that affect their perceptions.

Methods: A cross-sectional study using the Lean in Healthcare Questionnaire was conducted with 251 respondents, which consisted of doctors, nurses and medical assistants employed in three selected hospitals.

Results: One-way analysis of variance (ANOVA) showed a significant difference in every domain score in accordance with the occupation category. For the domain process, a significant negative correlation was found between age and domain score (r = …


Assessment Of Sociodemographic Status, Self-Awareness, And Risk Factors Affecting Patients With Prediabetes In Bangladesh: Cross-Sectional Study, Farhana Sultana, Muhammed Mohibul Islam, Aparajita Das, Md Hasan Shahriar Rahman, Nandita Islam Pia, Md Kayes Mahmud, Md. Saqline Mostaq, Saadullah Saadullah, Md. Saddam Hossain, Saikat Fakir, Mohammad Nurul Amin Apr 2024

Assessment Of Sociodemographic Status, Self-Awareness, And Risk Factors Affecting Patients With Prediabetes In Bangladesh: Cross-Sectional Study, Farhana Sultana, Muhammed Mohibul Islam, Aparajita Das, Md Hasan Shahriar Rahman, Nandita Islam Pia, Md Kayes Mahmud, Md. Saqline Mostaq, Saadullah Saadullah, Md. Saddam Hossain, Saikat Fakir, Mohammad Nurul Amin

Makara Journal of Health Research

Background: Poor glycemic control and high diabetes and prediabetes incidence are influenced by socioeconomic disparity. Raising awareness and ensuring that people with prediabetes are receiving medication, maintaining their glycemic control, and getting the proper care they need despite their socioeconomic situation are crucial in the fight against diabetes. This study aims to assess the sociodemographic status, self-awareness, and risk factors associated with prediabetes in Bangladesh.

Methods: A cross-sectional survey was carried out among 500 participants aged >18 years to evaluate and summarize their demographic data, socioeconomic status, and responses to various questionnaires about their conditions related to prediabetes …


Refining Successful Implementation Strategies For The Surgical Safety Checklist In High-Income Contexts: Results Of An International Mixed Methods Study, Meagan E. Elam, Christopher J. Louis, Jonathan Woodson, Nathan Turley, Denisa Urban, Mary E. Brindle, Jacey A. Greece Apr 2024

Refining Successful Implementation Strategies For The Surgical Safety Checklist In High-Income Contexts: Results Of An International Mixed Methods Study, Meagan E. Elam, Christopher J. Louis, Jonathan Woodson, Nathan Turley, Denisa Urban, Mary E. Brindle, Jacey A. Greece

Patient Experience Journal

The WHO Surgical Safety Checklist (SSC) continues to show inconsistent success in reducing surgical complications in high-income settings. Previous implementation research identified potential barriers and facilitators to success, but it primarily consists of qualitative studies with small sample sizes in limited geographic areas. We conducted a multi-country mixed-methods study of barriers and facilitators to SSC implementation to better inform policies and practices for improving SSC buy-in and use to maximize its impact. This convergent parallel mixed-methods study utilized survey and interview data from surgical team members practicing in five countries. Survey data were analyzed using χ2 analysis or Fisher’s …


Feasibility And Acceptability Of A Community Health Worker Administered Behavioral Activation Intervention For Postpartum Depression: A Single Arm Pilot Study From India, Amy Szajna, Bheemsain Tekkalaki, Veereshkumar Nandagaon, Gururaj Udapi, Manjunath Sogalad, Shweta Dandagi, Uma Kole, Sushma Patil, Sudha Raddi, Vanessa Short, Patricia Kelly Apr 2024

Feasibility And Acceptability Of A Community Health Worker Administered Behavioral Activation Intervention For Postpartum Depression: A Single Arm Pilot Study From India, Amy Szajna, Bheemsain Tekkalaki, Veereshkumar Nandagaon, Gururaj Udapi, Manjunath Sogalad, Shweta Dandagi, Uma Kole, Sushma Patil, Sudha Raddi, Vanessa Short, Patricia Kelly

College of Nursing Faculty Papers & Presentations

INTRODUCTION: Women in India experience high rates of postpartum depression (PPD), with minimal availability of screening or treatment. India has an extensive network of community health workers, known as accredited social health activists (ASHAs). While they are knowledgeable about most maternal-child health problems, they have minimal knowledge about PPD. We trained ASHAs to deliver a simple home-based intervention, behavioral activation (BA), which involves individuals in activities that are sources of positive reinforcement to counter depression. The research questions guiding this study were as follows: 1) What are the feasibility and acceptability of ASHAs screening for and delivering a brief behavioral …


Blastomas Of The Digestive System In Adults: A Review, Yu Liu, Tony El Jabbour, Jonathan Somma, Yukihiro Nakanishi, Saverio Ligato, Hwajeong Lee, Zhi-Yan Fu Apr 2024

Blastomas Of The Digestive System In Adults: A Review, Yu Liu, Tony El Jabbour, Jonathan Somma, Yukihiro Nakanishi, Saverio Ligato, Hwajeong Lee, Zhi-Yan Fu

School of Medicine Faculty Publications

Blastomas, characterized by a mixture of mesenchymal, epithelial, and undifferentiated blastematous components, are rare malignant neoplasms originating from precursor blast cells. This review focuses on digestive system blastomas in adult patients, including gastroblastoma, hepatoblastoma, and pancreatoblastoma. Gastroblastoma is a biphasic, epitheliomesenchymal tumor, with only sixteen cases reported to date. In addition to the characteristic histology, metastasis-associated lung adenocarcinoma transcript 1 - glioma-associated oncogene homolog 1 gene fusion is typical, although recently novel ewing sarcoma breakpoint region 1 - c-terminal binding protein 1 and patched 1 - glioma-associated oncogene homolog 2 fusions have been described. Hepatoblastoma is exceptionally rare in adults …


Comparing The Effects Of The Induction Of Anesthesia With Etomidate To The Induction Of Anesthesia With Midazolam On The Incidence Of In-Hospital Mortality: A Scoping Review, Madison Hayes Bsn, Rn, Ashley Lynch Bsn, Rn, Scott Jamison Bsn, Rn, Mary Joiner Bsn, Rn, Gray Seymour Bsn, Rn, Dwayne Accardo Dnp, Aprn, Crna, Tracy Mcclinton, Dnp, Aprn, Agacnp-Bc, Epb-C Apr 2024

Comparing The Effects Of The Induction Of Anesthesia With Etomidate To The Induction Of Anesthesia With Midazolam On The Incidence Of In-Hospital Mortality: A Scoping Review, Madison Hayes Bsn, Rn, Ashley Lynch Bsn, Rn, Scott Jamison Bsn, Rn, Mary Joiner Bsn, Rn, Gray Seymour Bsn, Rn, Dwayne Accardo Dnp, Aprn, Crna, Tracy Mcclinton, Dnp, Aprn, Agacnp-Bc, Epb-C

Doctor of Nursing Practice Projects

Purpose/Background

The induction of anesthesia using hypnotic sedatives, such as etomidate and midazolam, is common practice. Etomidate and midazolam are commonly employed in the induction of anesthesia in the septic patient population, each with its unique advantages and drawbacks. This scoping review aims to synthesize evidence on the effects of anesthetic induction with etomidate versus midazolam in adult septic patients, focusing on the incidence of mortality and associated adverse effects during hospitalization. The purpose is to establish a standard of care for anesthetic induction in this population.

Methods

A literature review was conducted from September 2022 to March 2023 utilizing …


Targeting Idh2r140q And Other Neoantigens In Acute Myeloid Leukemia, Wingchi K Leung, Alejandro G Torres Chavez, Matthew French-Kim, Paul Shafer, Maksim Mamonkin, Laquisa C Hill, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Norihiro Watanabe, Valentina Hoyos, Premal Lulla, Ann M Leen Apr 2024

Targeting Idh2r140q And Other Neoantigens In Acute Myeloid Leukemia, Wingchi K Leung, Alejandro G Torres Chavez, Matthew French-Kim, Paul Shafer, Maksim Mamonkin, Laquisa C Hill, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Norihiro Watanabe, Valentina Hoyos, Premal Lulla, Ann M Leen

Faculty, Staff and Students Publications

For patients with high-risk or relapsed/refractory acute myeloid leukemia (AML), allogeneic stem cell transplantation (allo-HSCT) and the graft-versus-leukemia effect mediated by donor T cells, offer the best chance of long-term remission. However, the concurrent transfer of alloreactive T cells can lead to graft-versus-host disease that is associated with transplant-related morbidity and mortality. Furthermore, ∼60% of patients will ultimately relapse after allo-HSCT, thus, underscoring the need for novel therapeutic strategies that are safe and effective. In this study, we explored the feasibility of immunotherapeutically targeting neoantigens, which arise from recurrent nonsynonymous mutations in AML and thus represent attractive targets because they …


Referral To In-Person Smoking Cessation Counseling As A Smoking Cessation Aid, Annie Mandrell Bsn, Rn, Matthew Keathley Bsn, Rn, Lewis Linden Bsn, Rn, Laura Reed Dnp, Aprn, Fnp-Bc, Cne Apr 2024

Referral To In-Person Smoking Cessation Counseling As A Smoking Cessation Aid, Annie Mandrell Bsn, Rn, Matthew Keathley Bsn, Rn, Lewis Linden Bsn, Rn, Laura Reed Dnp, Aprn, Fnp-Bc, Cne

Doctor of Nursing Practice Projects

Referral to In-Person Smoking Cessation Counseling as a Smoking Cessation Aid

Purpose/Background

Smoking increases an individual’s risk of acute and chronic disease morbidity and mortality, as well as creating a financial burden for the individual and healthcare system. In the United States, tobacco smoking is the leading cause of preventable death. There are an estimated 5 million tobacco-related deaths each year due to tobacco smoking. Additional healthcare costs are also seen due to the need for increased treatments, medical supplies, and staffing. Previous research for smoking cessation resources has primarily focused on traditional primary care offices. Research shows that in-person …


Impact Of Ehr On Security Check And Patient Outcomes, Arun Kumar Marumudi Apr 2024

Impact Of Ehr On Security Check And Patient Outcomes, Arun Kumar Marumudi

Harrisburg University Dissertations and Theses

This study aims to explore patient perspectives on how electronic health record (EHR) security protocols influence care quality and outcomes. In the context of methodology, an online survey was conducted in March 2024 with 10 participants from the USA who provided informed consent. Questions assessed experience with EHRs, security concerns, perceptions of authentication impacts, satisfaction with balancing priorities, and open-ended feedback. Descriptive analysis was used to identify key themes.

Most respondents had direct EHR exposure, which validated their viewpoints. Universal concerns co-existed with preferring digital records due to facilitated sharing when regulated appropriately. One-third reported occasional access issues correlating with …


Centralized Interactive Phenomics Resource: An Integrated Online Phenomics Knowledgebase For Health Data Users, Jacqueline Honerlaw, Yuk-Lam Ho, Francesca Fontin, Michael Murray, Ashley Galloway, David Heise, Keith Connatser, Laura Davies, Jeffrey Gosian, Monika Maripuri, John Russo, Rahul Sangar, Vidisha Tanukonda, Edward Zielinski, Maureen Dubreuil, Andrew J Zimolzak, Vidul A Panickan, Su-Chun Cheng, Stacey B Whitbourne, David R Gagnon, Tianxi Cai, Katherine P Liao, Rachel B Ramoni, J Michael Gaziano, Sumitra Muralidhar, Kelly Cho Apr 2024

Centralized Interactive Phenomics Resource: An Integrated Online Phenomics Knowledgebase For Health Data Users, Jacqueline Honerlaw, Yuk-Lam Ho, Francesca Fontin, Michael Murray, Ashley Galloway, David Heise, Keith Connatser, Laura Davies, Jeffrey Gosian, Monika Maripuri, John Russo, Rahul Sangar, Vidisha Tanukonda, Edward Zielinski, Maureen Dubreuil, Andrew J Zimolzak, Vidul A Panickan, Su-Chun Cheng, Stacey B Whitbourne, David R Gagnon, Tianxi Cai, Katherine P Liao, Rachel B Ramoni, J Michael Gaziano, Sumitra Muralidhar, Kelly Cho

Faculty, Staff and Students Publications

Objective: Development of clinical phenotypes from electronic health records (EHRs) can be resource intensive. Several phenotype libraries have been created to facilitate reuse of definitions. However, these platforms vary in target audience and utility. We describe the development of the Centralized Interactive Phenomics Resource (CIPHER) knowledgebase, a comprehensive public-facing phenotype library, which aims to facilitate clinical and health services research.

Materials and methods: The platform was designed to collect and catalog EHR-based computable phenotype algorithms from any healthcare system, scale metadata management, facilitate phenotype discovery, and allow for integration of tools and user workflows. Phenomics experts were engaged in the …


Implementation Of Psychiatric Collaborative Care Management In Rural Primary Care Practices, Ryan Dean Kruis Apr 2024

Implementation Of Psychiatric Collaborative Care Management In Rural Primary Care Practices, Ryan Dean Kruis

MUSC Theses and Dissertations

Behavioral health (BH) disorders are highly prevalent in the United States and especially concerning in rural communities which disproportionately lack access to BH services. While models for integrating BH into primary care, such as psychiatric collaborative care management (CoCM), have shown promise in mitigating the BH crisis, implementation in rural communities has proved challenging.
This dissertation examines implementation of CoCM nationally and in rural settings through three distinct aims. First, a claims-based retrospective cohort study was used to determine whether commercially insured patients receiving CoCM had lower acute BH care utilization and cost as compared to similar patients not receiving …


Evidenced-Based Strategies To Increase Cervical Cancer Screening Rates, Tuong Cat Vo Bsn-Rn, Nada Salloukh Bsn-Rn, Tatiana Elena Swanson Bsn-Rn, Xiao Mie Cindy Zhu Bsn-Rn, Laura Taylor Reed Dnp, Aprn, Fnp-Bc Apr 2024

Evidenced-Based Strategies To Increase Cervical Cancer Screening Rates, Tuong Cat Vo Bsn-Rn, Nada Salloukh Bsn-Rn, Tatiana Elena Swanson Bsn-Rn, Xiao Mie Cindy Zhu Bsn-Rn, Laura Taylor Reed Dnp, Aprn, Fnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Cervical cancer is the fourth leading cause of cancer affecting women worldwide (Staley et al., 2021). With cervical cancer being a preventable disease, an effective method of reducing healthcare costs and mortality is primary prevention, such as screenings. Financial burdens and barriers to accessing medical care may result due to the lack of proper cervical cancer screenings. Detecting cervical cancer includes screening women 21 to 65 years old with a Papanicolaou (PAP) test every three years. Women aged 30 to 65 years old can extend the screening of cervical cancer by having a Human Papillomavirus (HPV) test along with …


Exploring The Experience Of Healthcare-Related Epistemic Injustice Among People With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Joanne Hunt, Jessica Runacres, Daniel Herron, David Sheffield Apr 2024

Exploring The Experience Of Healthcare-Related Epistemic Injustice Among People With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Joanne Hunt, Jessica Runacres, Daniel Herron, David Sheffield

The Qualitative Report

Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a chronic, disabling yet clinically “contested” condition, previously theorised through a lens of epistemic injustice. Phenomena conceptually close to epistemic injustice, including stigma, are known to have deleterious consequences on a person’s health and life-world. Yet, no known primary studies have explored how people with ME/CFS experience healthcare through a lens of epistemic injustice, whilst a dearth of research explicitly exploring healthcare-related injustice from a patient perspective has been noted. This qualitative study seeks to address this gap. Semi-structured interviews and interpretative phenomenological analysis (IPA) were used to explore the experiences of …


Lai Antipsychotics Vs. Oral Antipsychotics: Treatment Adherence, Relapses, And Readmissions, Natalie N. Lewis Bsn, Rn, Mallory F. Johnson Bsn, Rn-Bc, Tyler N. Halle-Todd Bsn, Rn, Natalie N. Ragland Bsn, Rn, Sharon H. Little Dnp, Aprn, Fnp-Bc, Jacqueline Sharp Dnp, Aprn,Pmhnp-Bc Apr 2024

Lai Antipsychotics Vs. Oral Antipsychotics: Treatment Adherence, Relapses, And Readmissions, Natalie N. Lewis Bsn, Rn, Mallory F. Johnson Bsn, Rn-Bc, Tyler N. Halle-Todd Bsn, Rn, Natalie N. Ragland Bsn, Rn, Sharon H. Little Dnp, Aprn, Fnp-Bc, Jacqueline Sharp Dnp, Aprn,Pmhnp-Bc

Doctor of Nursing Practice Projects

Purpose/Background

Schizophrenia is a lifelong illness with recurrent and often debilitating symptoms that may impair daily functioning, cognition, behaviors, socialization, emotions, and expression. It is recognized as a global mental health burden that affects the individual, their family, and society. Medication nonadherence and resulting relapse detrimentally affect the patient’s physical and mental health and quality of life. They are associated with increased hospitalization and emergency room visits, substance use, suicide, and homelessness. Current guidelines endorse second-generation antipsychotics such as Risperidone and Aripiprazole as the first-line treatment for most cases of psychosis. However, long-acting injectable (LAIs) atypical antipsychotics are a promising …


Assessment Of Condylar Morphology In Various Facial Types-Cbct Study, Dr.Shruti Patil Apr 2024

Assessment Of Condylar Morphology In Various Facial Types-Cbct Study, Dr.Shruti Patil

Annual Research Symposium

Mandibular condyle being part of the TMJ complex, its volume and shape play a pivotal role in treatment stability and outcomes in orthodontic and orthognathic patients over long term periods. Different loading patterns would result in different morphology of the TMJ. The association with different facial types and understanding the relationship between condylar position, morphology and jaw base divergence is limited. This study’s objective is to assess the condylar structure which includes condylar height, width and height of the fossa in different jaw base divergences.

A cross-sectional study was conducted in which 90 patients undergoing Orthodontic treatment were selected and …


Multi-Omics Analysis Reveals Immune Features Associated With Immunotherapy Benefit In Patients With Squamous Cell Lung Cancer From Phase Iii Lung-Map S1400i Trial, Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W Redman, Hong Chen, Ganiraju C Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E Gray, Roy S Herbst, Ignacio I Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J Jack Lee, Jianjun Zhang, Cara Haymaker Apr 2024

Multi-Omics Analysis Reveals Immune Features Associated With Immunotherapy Benefit In Patients With Squamous Cell Lung Cancer From Phase Iii Lung-Map S1400i Trial, Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W Redman, Hong Chen, Ganiraju C Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E Gray, Roy S Herbst, Ignacio I Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J Jack Lee, Jianjun Zhang, Cara Haymaker

Faculty, Staff and Student Publications

PURPOSE: Identifying molecular and immune features to guide immune checkpoint inhibitor (ICI)-based regimens remains an unmet clinical need.

EXPERIMENTAL DESIGN: Tissue and longitudinal blood specimens from phase III trial S1400I in patients with metastatic squamous non-small cell carcinoma (SqNSCLC) treated with nivolumab monotherapy (nivo) or nivolumab plus ipilimumab (nivo+ipi) were subjected to multi-omics analyses including multiplex immunofluorescence (mIF), nCounter PanCancer Immune Profiling Panel, whole-exome sequencing, and Olink.

RESULTS: Higher immune scores from immune gene expression profiling or immune cell infiltration by mIF were associated with response to ICIs and improved survival, except regulatory T cells, which were associated with worse …


Clearing The Air: Innovations In Imaging For Early Detection And Management Of Chronic Obstructive Pulmonary Disease, Francesca Polverino Apr 2024

Clearing The Air: Innovations In Imaging For Early Detection And Management Of Chronic Obstructive Pulmonary Disease, Francesca Polverino

Faculty, Staff and Students Publications

No abstract provided.


Detecting The 2-Micron Plasmid In Saccharomyces Cerevisiae, Caitlin C. Allen, Eric T. Gillock Apr 2024

Detecting The 2-Micron Plasmid In Saccharomyces Cerevisiae, Caitlin C. Allen, Eric T. Gillock

SACAD: Scholarly Activities

This research is a continuation of work started by a previous student, Camryn Greving. Camryn was screening for the presence of the 2-micron plasmid using PCR primers specific for the REP2 gene, devised by Nakayashiki et al. In this research, we confirmed the presence of the plasmid by using primers specific for the RAF1 gene, which were designed by Strope et al.


An Ot Needs Assessment For Children And Families Residing In Shelters, Jessie Siono, Susan Macdermott Apr 2024

An Ot Needs Assessment For Children And Families Residing In Shelters, Jessie Siono, Susan Macdermott

Spring 2024 Virtual OTD Capstone Symposium

This study created a needs assessment is to determine the unique occupational deficits of children and their families in California experiencing homelessness within a shelter setting via recording their lived experiences. A local family shelter was analyzed via observation and interviews with staff and residents of the shelter. The results were compiled into a facility assessment to identify supports and barriers to occupation. Results were also utilized to complete an occupational needs assessment for families and children living in homeless shelters. The study determined the occupational needs and occurrences of occupational deficits that were experienced by residents of the family …


The Dearth Of Knowledge Of Health Insurance Literacy Within The United States, Katherine A. Conzet Apr 2024

The Dearth Of Knowledge Of Health Insurance Literacy Within The United States, Katherine A. Conzet

Honors Thesis

This literature review and cross-comparison were conducted to combine resources that bring to light the lack of knowledge on health insurance, the impact of this low health insurance literacy (HIL), and the lack of research being done in this subject field. This thesis analyzes and compares different research that measures HIL levels and compares these findings. At the same time, this thesis presents the complex history of health insurance and how this understanding can contribute to lower population HIL and proposes different ways to accurately measure HIL. The purpose is to show the necessity for more research into the field …


Evaluation Of Four Computed Tomography Reconstruction Algorithms Using A Coronary Artery Phantom, Shungo Sawamura, Shingo Kato, Yoshinori Funama, Seitaro Oda, Harumi Mochizuki, Sayuri Inagaki, Yuka Takeuchi, Tsubasa Morioka, Toshiharu Izumi, Yoichiro Ota, Hironori Kawagoe, Shihyao Cheng, Naoki Nakayama, Kazuki Fukui, Takashi Tsutsumi, Tae Iwasawa, Daisuke Utsunomiya Apr 2024

Evaluation Of Four Computed Tomography Reconstruction Algorithms Using A Coronary Artery Phantom, Shungo Sawamura, Shingo Kato, Yoshinori Funama, Seitaro Oda, Harumi Mochizuki, Sayuri Inagaki, Yuka Takeuchi, Tsubasa Morioka, Toshiharu Izumi, Yoichiro Ota, Hironori Kawagoe, Shihyao Cheng, Naoki Nakayama, Kazuki Fukui, Takashi Tsutsumi, Tae Iwasawa, Daisuke Utsunomiya

Faculty, Staff and Student Publications

BACKGROUND: Despite advancements in coronary computed tomography angiography (CTA), challenges in positive predictive value and specificity remain due to limited spatial resolution. The purpose of this experimental study was to investigate the effect of 2nd generation deep learning-based reconstruction (DLR) on the quantitative and qualitative image quality in coronary CTA.

METHODS: A vessel model with stepwise non-calcified plaque was scanned using 320-detector CT. Image reconstruction was performed using four techniques: hybrid iterative reconstruction (HIR), model-based iterative reconstruction (MBIR), DLR, and 2nd generation DLR. The luminal peak CT number, contrast-to-noise ratio (CNR), and edge rise slope (ERS) were quantitatively evaluated via …


Analisis Spasial Faktor Risiko Difteri Di Provinsi Lampung Tahun 2022 Dan 2023, Nada Izzata Kamilla, Feranita Utama, Noviani Noviani Apr 2024

Analisis Spasial Faktor Risiko Difteri Di Provinsi Lampung Tahun 2022 Dan 2023, Nada Izzata Kamilla, Feranita Utama, Noviani Noviani

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Difteri merupakan penyakit menular yang disebabkan oleh bakteri Corynebacterium diphtheriae. Bila ditemukan satu kasus difteri di suatu wilayah maka dapat ditetapkan sebagai KLB. Provinsi Lampung terus mengalami kenaikan kasus dan suspek difteri sejak 2020 dan turut menyumbang angka kematian akibat difteri pada tahun 2023. Kasus difteri dipengaruhi oleh beberapa faktor risiko. Penelitian ini bertujuan untuk mendapatkan gambaran distribusi dan faktor risiko kasus difteri di Provinsi Lampung dengan memetakan kabupaten/kota berdasarkan persebaran dan faktor risikonya. Penelitian ini menggunakan desain studi ekologi dengan metode deskriptif analitik dengan aplikasi Quantum GIS versi 3.28.3. Hasil menunjukan distribusi kejadian difteri di Provinsi …


Analysis Of User Satisfaction Of Telemedicine Services During Covid-19 Self-Isolation Among Fph Students At The Universitas Indonesia, Fathiya Nissa Mulyaningrum, Nadya Raihanny Apr 2024

Analysis Of User Satisfaction Of Telemedicine Services During Covid-19 Self-Isolation Among Fph Students At The Universitas Indonesia, Fathiya Nissa Mulyaningrum, Nadya Raihanny

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Telemedicine has become a new paradigm in the world of health since its popular use to assist the Ministry of Health in monitoring self-isolating patients during the COVID-19 pandemic. This study aims to analyze service quality variables related to user satisfaction with telemedicine services during COVID-19 self-isolation among students in FPH UI. This research is quantitative research with a cross-sectional approach. The results show that the platform most widely used for telemedicine services during the COVID-19 pandemic was platform H by 25 people. The average satisfaction of telemedicine users during self-isolation tends to be high, namely 3.8 with the lowest …


Sistem Monitoring Dan Evaluasi Serta Perkembangan Program Pencegahan Dan Pengendalian Penyakit Tuberkulosis Di Dinas Kesehatan Kota Depok, Supriyanti Supriyanti, Tiur Febrina Pohan, Kemal N. Siregar Apr 2024

Sistem Monitoring Dan Evaluasi Serta Perkembangan Program Pencegahan Dan Pengendalian Penyakit Tuberkulosis Di Dinas Kesehatan Kota Depok, Supriyanti Supriyanti, Tiur Febrina Pohan, Kemal N. Siregar

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Beban kasus TB tertinggi tahun 2021 terjadi di Provinsi Jawa Barat, Jawa Timur, Jawa Tengah, Sumatera Utara, dan DKI Jakarta. Kota Depok merupakan salah satu penyumbang beban TB di Jawa Barat. Dari data estimasi beban TB se-Provinsi Jawa Barat, Kota Depok berada di urutan ke-7 dengan estimasi jumlah kasus sebanyak 3853 kasus. Menurut indikator angka keberhasilan pengobatan pasien TB, semua kasus tahun 2018-2021 masih dibawah target 90%. Tujuan penelitian ini untuk mengetahui hasil monitoring dan evaluasi program TB yang telah berjalan di Seksi Pencegahan dan Pengendalian Penyakit Menular serta perkembangan program TB dilihat dari capaian indikator TB di Dinas Kesehatan …


Hubungan Berat Derajat Merokok Terhadap Kelainan Fungsi Paru Pada Sopir Angkutan Umum Di Terminal Kampung Melayu, Rizaldi Ridwan, Fajaria Nurcandra, Chandrayani Simanjorang, Dyah Utari, Balqis Hiri Bahasoan Apr 2024

Hubungan Berat Derajat Merokok Terhadap Kelainan Fungsi Paru Pada Sopir Angkutan Umum Di Terminal Kampung Melayu, Rizaldi Ridwan, Fajaria Nurcandra, Chandrayani Simanjorang, Dyah Utari, Balqis Hiri Bahasoan

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Di Indonesia, terdapat sebanyak 9,2 juta jiwa penyakit kelainan fungsi paru. Sopir angkutan umum yang merokok berisiko mengalami kelainan fungsi paru yang diakibatkan oleh rokok. Penelitian ini bertujuan untuk menganalisis hubungan berat derajat merokok terhadap gejala kelainan fungsi paru pada sopir angkutan umum di Terminal Kampung Melayu. Penelitian ini dilaksanakan pada bulan Mei tahun 2023 di Terminal Kampung Melayu dengan desain cross-sectional pada 102 sopir angkutan umum sebagai sampel. Sampel dipilih menggunakan teknik purposive sampling dengan kriteria inklusi sopir angkutan umum dan bersedia diwawancara. Wawancara langsung dilakukan menggunakan kuesioner dan spirometri untuk mengukur fungsi paru. Data dianalisis menggunakan uji Cox …


Persepsi Masyarakat Perdesaan Terhadap Penerimaan Vaksinasi Covid-19 Tahap Iii (Booster), Irma Irma, Yusuf Sabilu, Besse Amelia Apr 2024

Persepsi Masyarakat Perdesaan Terhadap Penerimaan Vaksinasi Covid-19 Tahap Iii (Booster), Irma Irma, Yusuf Sabilu, Besse Amelia

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Penerimaan vaksinasi COVID-19 tahap III (booster) tiap kabupaten/kota di Provinsi Sulawesi Selatan memperoleh cakupan yang berbeda-beda. Jika dibandingkan dengan kabupaten/kota lainnya, Kabupaten Wajo memperoleh cakupan vaksin COVID-19 tahap III (booster) masih rendah yaitu 14.06%, dimana Desa Watan Rumpia memiliki persentase cakupan vaksinasi COVID-19 tahap III (booster) terendah per 16 Agustus 2022. Hal ini disebabkan karena persepsi dari masyarakat itu sendiri dalam menanggapi penerimaan vaksinasi COVID-19 tahap III (booster). Penelitian ini bertujuan untuk mengetahui hubungan antara persepsi masyarakat mengenai kerentanan, keparahan, manfaat dengan penerimaan vaksinasi COVID-19 tahap III (booster) di Desa …