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Full-Text Articles in Public Health

A Standardized Approach To Blood Pressure Training In First-Year Medical Students, Andrew Romney Mar 2022

A Standardized Approach To Blood Pressure Training In First-Year Medical Students, Andrew Romney

Annual Research Symposium

No abstract provided.


Perception Of Electronic Cigarettes Among Dental Students, Ryan Kinney Mar 2022

Perception Of Electronic Cigarettes Among Dental Students, Ryan Kinney

Annual Research Symposium

No abstract provided.


Using A Reconciliatory Model To Change Attitudes Towards Covid-19, Gabriella Hubble, Mark Rockwood, Jordan Willis Mar 2022

Using A Reconciliatory Model To Change Attitudes Towards Covid-19, Gabriella Hubble, Mark Rockwood, Jordan Willis

Annual Research Symposium

This research was designed to see if we were able to change university students’ attitudes about COVID-19 in regard to precautionary behaviors such as mask-wearing, social distancing and vaccinations using a reconciliatory model. The reconciliatory model has had success in evolution research and we wanted to assess its success here. Additionally, we wanted to test if students’ perception of the respectfulness and relatability of the presenter influenced a change in attitude. For our model, we created 6 different videos from various individuals. After watching the videos, participants filled out a survey about if/how the video changed their minds, and if/how …


Identifying Bias In Healthcare And Creating Intervention Strategies At Colleges Of Medicine And Other Healthcare Professions, Cameron Chalmers, Emmanuel Oyalabu Mar 2022

Identifying Bias In Healthcare And Creating Intervention Strategies At Colleges Of Medicine And Other Healthcare Professions, Cameron Chalmers, Emmanuel Oyalabu

Annual Research Symposium

No abstract provided.


Current Trends In The Sars-Cov-2 Pandemic During The Emergence Of The Omicron Variant, Benjamin Mennell Mar 2022

Current Trends In The Sars-Cov-2 Pandemic During The Emergence Of The Omicron Variant, Benjamin Mennell

Annual Research Symposium

No abstract provided.


Identification Of Gsk-3 Beta Inhibitors From Natural Products, Vincent Anella, Tyler Rose Mar 2022

Identification Of Gsk-3 Beta Inhibitors From Natural Products, Vincent Anella, Tyler Rose

Annual Research Symposium

No abstract provided.


Periodontitis & Increased Cognitive Decline In Alzheimer's Disease, Nomikos Klonaris Mar 2022

Periodontitis & Increased Cognitive Decline In Alzheimer's Disease, Nomikos Klonaris

Annual Research Symposium

No abstract provided.


Prediction Of Human Transcriptional Biomarkers For Severe Infection With Sars-Cov-2, Jeffrey Clancy, Brett Pickett Mar 2022

Prediction Of Human Transcriptional Biomarkers For Severe Infection With Sars-Cov-2, Jeffrey Clancy, Brett Pickett

Annual Research Symposium

Defining the human host factors associated with severe vs mild COVID-19 cases in infected individuals has become of increasing interest. Mining large numbers of public gene expression datasets is an effective way to identify genes that contribute to a given phenotype. Combining RNA-sequencing data with the associated clinical metadata describing disease severity can enable earlier identification of those patients who are at higher risk of developing severe COVID-19 disease. We consequently identified 356 public RNA-seq human transcriptome samples from the Gene Expression Omnibus database that had disease severity metadata. We then subjected these samples to a robust RNA-seq data processing …


The Role Of Cd5 In The Periodontal Disease: Insights Into Chronic Inflammation, Ellie Bybee Mar 2022

The Role Of Cd5 In The Periodontal Disease: Insights Into Chronic Inflammation, Ellie Bybee

Annual Research Symposium

No abstract provided.


A Quantitative Analysis Of The Efficacy Of Various Essential Oils Against The Sars Cov-2 Virus, Elizabeth Wagstaff, Chandrelyn Kraczek, Jack Brandon Lopez Mar 2022

A Quantitative Analysis Of The Efficacy Of Various Essential Oils Against The Sars Cov-2 Virus, Elizabeth Wagstaff, Chandrelyn Kraczek, Jack Brandon Lopez

Annual Research Symposium

A poster presentation and abstract for the Roseman Symposium. The project focuses on testing 3 essential oil blends and two disinfectants containing an essential oil blend against SARS CoV-2 in response to the COVID-19 pandemic. The project procedure involves plaque assays, disinfection, and neutralization techniques.


Number Of Active Social Media Users As Predictors Of Hipaa Infringements, Alexander Sheppert, Taylor Purcell, Nathaniel Hill, David Sant Mar 2022

Number Of Active Social Media Users As Predictors Of Hipaa Infringements, Alexander Sheppert, Taylor Purcell, Nathaniel Hill, David Sant

Annual Research Symposium

HIPAA Infringements Correlate Linearly with Number of Social Media Users.

Social media use has made information sharing much easier – including protected health information. Interestingly, as social media has become more popular over the years, HIPAA violations have also become more common.

The calculated R and P values suggest a strong correlation exists between social media use and HIPAA complaints.


Utilization Of Medi-Cal Dental Benefits, Beatrice Bautista Mar 2022

Utilization Of Medi-Cal Dental Benefits, Beatrice Bautista

Annual Research Symposium

No abstract provided.


Potential Cost Savings With Implementation Of Systemwide Rasburicase Protocol, Parker Gundersen, Adalyn Lee Mar 2022

Potential Cost Savings With Implementation Of Systemwide Rasburicase Protocol, Parker Gundersen, Adalyn Lee

Annual Research Symposium

Purpose: Tumor Lysis Syndrome is a condition that takes place when apoptosis in cancer cells occurs within a short time period. This condition can lead to organ dysfunction and even death. Rasburicase is used to treat high uric acid levels in patients that are experiencing tumor lysis syndrome and is expensive. Dosing and frequency of rasburicase varies across health care institutions. This project evaluated if adherence to a systemwide rasburicase protocol could help reduce drug waste and reduce costs across a healthcare system.

Methods: We conducted a retrospective data analysis reviewing rasburicase doses administered across Intermountain Healthcare over the course …


Comparing The Efficacy Of Sodium Fluoride And Silver Diamine Fluoride In Arresting Caries Through Statistical Analysis, Elana Ferris Mar 2022

Comparing The Efficacy Of Sodium Fluoride And Silver Diamine Fluoride In Arresting Caries Through Statistical Analysis, Elana Ferris

Annual Research Symposium

No abstract provided.


Perceptions And Practices Of Key Worker Stakeholder Groups In Hospital Animal- Assisted Intervention Programs On Occupational Benefits And Perceived Risks, Kathryn R. Dalton, William Altekruse, Peter Campbell, Kathy Ruble, Karen C. Carroll, Roland J. Thorpe Jr., Jacqueline Agnew, Meghan F. Davis Mar 2022

Perceptions And Practices Of Key Worker Stakeholder Groups In Hospital Animal- Assisted Intervention Programs On Occupational Benefits And Perceived Risks, Kathryn R. Dalton, William Altekruse, Peter Campbell, Kathy Ruble, Karen C. Carroll, Roland J. Thorpe Jr., Jacqueline Agnew, Meghan F. Davis

People and Animals: The International Journal of Research and Practice

Background: Animal-assisted intervention (AAI) programs, used widely for patient benefit, have increasingly been used for healthcare workers (HCW) to reduce occupational stress. However, there are barriers to these programs which limit their utilization, for both patients and HCW, specifically infectious disease concerns. The aim of the research project is to identify barriers and facilitators to AAI program use for healthcare worker benefit, and determine knowledge, beliefs, and practices regarding infectious disease risk and control policies, in order to understand the contextual parameters of program implementation.

Methods: We collected perceptions of key stakeholders involved with hospital AAI programs (HCW and AAI …


Hubungan Aktivitas Fisik Dengan Diabetes Melitus Pada Wanita Usia 20-25 Di Dki Jakarta (Analisis Data Posbindu Ptm 2019), Nurrahma Fitria Ramadhani, Kemal N. Siregar, Verry Adrian, Intan Rachmita Sari, Hardya Gustada Hikmahrachim Mar 2022

Hubungan Aktivitas Fisik Dengan Diabetes Melitus Pada Wanita Usia 20-25 Di Dki Jakarta (Analisis Data Posbindu Ptm 2019), Nurrahma Fitria Ramadhani, Kemal N. Siregar, Verry Adrian, Intan Rachmita Sari, Hardya Gustada Hikmahrachim

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Diabetes melitus adalah penyakit kronis yang terjadi karena kelainan sekresi insulin, kerja insulin atau keduanya. Diabetes melitus masih menjadi masalah di seluruh dunia terutama di negara berkembang. Tujuan penelitian ini untuk melihat hubungan aktivitas fisik dengan diabetes melitus pada wanita usia 20-25 tahun. Penelitian ini menggunakan data Posbindu DKI Jakarta tahun 2019 dengan desain potong lintang yang melibatkan 1479 subjek wanita usia 20-25 tahun yang berkunjung ke Posbindu. Dilakukan analisis statistik univariat, bivariat chi square (CI: 95%) untuk melihat hubungan aktivitas fisik dan diabetes melitus, serta analisis multivariat regresi logistik untuk melihat hubungan aktivitas fisik dan diabetes melitus setelah di …


Identifikasi Atribut Dengan Principal Component Analysis Dan K-Means Clustering Sebagai Dasar Penyusunan Strategi Promosi Kb Pria Di Indonesia, Titis Risti Yulianti, Kemal N. Siregar, Artha Prabawa Mar 2022

Identifikasi Atribut Dengan Principal Component Analysis Dan K-Means Clustering Sebagai Dasar Penyusunan Strategi Promosi Kb Pria Di Indonesia, Titis Risti Yulianti, Kemal N. Siregar, Artha Prabawa

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Penggunaan kontrasepsi pria sangat rendah dibandingkan wanita di Indonesia, serta terdapat gap cukup jauh antara penggunaan kontrasepsi pria di Indonesia dengan beberapa negara di Asia. Penelitian ini bertujuan untuk menentukan strategi promosi KB pria di Indonesia. Analisis data dilakukan dengan metode Principal Component Analysis (PCA) dan k-means clustering menggunakan 4.453 responden SDKI 2017 mengenai penggunaan KB pria dengan 14 atribut. Hasil penelitian berdasarkan PCA didapatkan 5 principal component, kemudian hasil k-means clustering didapatkan 2 cluster meliputi cluster 1 dan cluster 2. Cluster 1 meliputi 411 pria kawin dengan penggunaan KB pria yang baik dan menduduki sebagian kecil provinsi di …


Evaluasi Pengelolaan Data Dan Informasi Program Vaksinasi Covid-19 (Corona Virus Disease 19) Di Wilayah Lampung Tahun 2021, Regina Valya Puspita Araytri, Milla Herdayati Mar 2022

Evaluasi Pengelolaan Data Dan Informasi Program Vaksinasi Covid-19 (Corona Virus Disease 19) Di Wilayah Lampung Tahun 2021, Regina Valya Puspita Araytri, Milla Herdayati

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Pengelolaan data dan informasi pada program vaksinasi merupakan suatu hal penting yang harus diperhatikan pelaksanaannya. Hal ini dikarenakan proses pencatatan dan pelaporan data pada yang dilaksanakan pada program vaksinasi dapat menunjang percepatan vaksinasi di Indonesia karena dapat mengetahui cakupan vaksinasi yang telah terlaksana. Penelitian ini bertujuan untuk mengamati pengelolaan data dan informasi seputar program vaksinasi COVID-19 (Corona Virus Disease 2019) di wilayah Lampung. Penelitian ini merupakan penelitian ini merupakan penelitian deskriptif dengan pendekatan observasional pada pelayanan kesehatan sekunder (Dinas Kesehatan Provinsi Lampung) responden pada penelitian ini adalah kepala seksi surveilans dan imunisasi dinas kesehatan Provinsi Lampung. Pengumpulan data dilakukan …


Penggabungan Aplikasi Telemedicine Tb Sebagai Optimalisasi Pelayanan Tb Selama Masa Pandemi Covid-19, Dian Septiani, Fanesya Nuur Haniifah, Meta Alya Riswaluyo, Najiah Meirina Anwar Mar 2022

Penggabungan Aplikasi Telemedicine Tb Sebagai Optimalisasi Pelayanan Tb Selama Masa Pandemi Covid-19, Dian Septiani, Fanesya Nuur Haniifah, Meta Alya Riswaluyo, Najiah Meirina Anwar

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Selama masa pandemi COVID-19, upaya penanganan TB menjadi terhambat. Upaya penanganan TB saat masa pandemi dapat dilakukan dengan memanfaatkan teknologi digital. Yayasan KNCV Indonesia (YKI) bersama Kemenkes RI mengembangkan aplikasi dalam mendukung program TB yaitu SOBAT TB dan EMPATI Client. Kedua aplikasi tersebut memiliki fungsi yang sama yaitu untuk upaya eliminasi TB namun aplikasi tersebut tidak disatukan sehingga pelayanan tidak terintegrasi. Oleh karena itu, diperlukan adanya penggabungan antara aplikasi SOBAT TB dan EMPATI Client. Metode yang digunakan dalam penelitian ini adalah tinjauan literatur (Literature review) dari berbagai sumber. Diperlukan adanya penggabungan aplikasi SOBAT TB dan Empati Client …


Pengklasteran Kepatuhan Konsumsi Tablet Tambah Darah Pada Wanita Usia Subur Menggunakan Metode Principal Component Analysis Dan K-Means, Hasnia Jondu, Kemal N. Siregar, Artha Prabawa, Nurul Fadhilah Mar 2022

Pengklasteran Kepatuhan Konsumsi Tablet Tambah Darah Pada Wanita Usia Subur Menggunakan Metode Principal Component Analysis Dan K-Means, Hasnia Jondu, Kemal N. Siregar, Artha Prabawa, Nurul Fadhilah

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Anemia pada ibu hamil adalah kondisi di mana kadar Hb < 11 gr/dL. Prevalensi anemia di Indonesia cukup tinggi yaitu sebesar 44%. Target penurunan anemia dapat dicapai melalui program suplementasi zat besi dan asam folat (program IFAS). Indonesia telah sejak 1975 merekomendasikan ibu hamil minum satu tablet IFA selama kehamilan minimal 90 hari hingga 42 hari pasca melahirkan. Hasil Riskesdas 2018, Ibu hamil yang mengonsumsi TTD ≥90 butir adalah sebesar 38,1%, sedangkan data mining.Penelitian ini memadukan metode PCA dan K-Means. Peneliti menggunakan data SDKI Wanita Usia Subur 2017. Data terdiri dari 8 atribut dan 12262 record. Hasil penelitian ini yaitu hasil final cluster metode PCA menghasilkan faktor 1 (Pendidikan, Status Ekonomi, dan Tempat Tinggal), faktor 2 (Konsumsi TTD dan Kunjungan ANC), faktor 3 (Pemeriksa Hamil: Non-Nakes). Hasil metode K-Means terbentuk dua klaster dan ketiga atribut baru terdapat signifikansi.


“This Isn’T Just Busy, This Is Scary”: Stress, Social Support, And Coping Experiences Of Frontline Nurses During The Covid-19 Pandemic, Erin S. Craw, Tess M. Buckley, Michelle Miller-Day Mar 2022

“This Isn’T Just Busy, This Is Scary”: Stress, Social Support, And Coping Experiences Of Frontline Nurses During The Covid-19 Pandemic, Erin S. Craw, Tess M. Buckley, Michelle Miller-Day

Communication Faculty Articles and Research

Despite having previous experience and extensive trauma training, the COVID-19 pandemic presented unprecedented challenges for nurses working in hospital settings. During the pandemic, nurses struggle to care for patients and protect themselves from infection, while navigating ongoing organizational changes. Guided by prior literature on social support and coping, this study explores nurses’ experiences of coping with stress while treating COVID-19 patients during the pandemic. In-depth semi-structured interviews were conducted with 14 active staff nurses working in hospitals and one licensed practical nurse (LPN) at a rehabilitation center who treated COVID-19 patients during the pandemic. An inductive thematic analysis was employed …


Triglyceride-Rich Lipoproteins, Apolipoprotein C-Iii, Angiopoietin-Like Protein 3, And Cardiovascular Events In Older Adults: Atherosclerosis Risk In Communities (Aric) Study, Aliza Hussain, Caroline Sun, Elizabeth Selvin, Vijay Nambi, Josef Coresh, Xiaoming Jia, Christie M Ballantyne, Ron C Hoogeveen Mar 2022

Triglyceride-Rich Lipoproteins, Apolipoprotein C-Iii, Angiopoietin-Like Protein 3, And Cardiovascular Events In Older Adults: Atherosclerosis Risk In Communities (Aric) Study, Aliza Hussain, Caroline Sun, Elizabeth Selvin, Vijay Nambi, Josef Coresh, Xiaoming Jia, Christie M Ballantyne, Ron C Hoogeveen

Faculty, Staff and Students Publications

AIMS: Despite statin and antihypertensive therapies, older Americans have high atherosclerotic cardiovascular disease (ASCVD) risk. Novel measures of triglyceride-rich lipoproteins, low-density lipoprotein triglycerides (LDL-TG), and remnant-like particle cholesterol (RLP-C), are associated with ASCVD in middle-aged adults. Polymorphisms in genes encoding angiopoietin-related protein 3 (ANGPTL3) and apolipoprotein C-III (apoC-III), two proteins involved in triglyceride catabolism, are associated with increased risk for hypertriglyceridaemia and ASCVD and are potential therapeutic targets. We examined associations of LDL-TG, RLP-C, apoC-III, and ANGPTL3 levels with ASCVD events in older adults in the Atherosclerosis Risk in Communities (ARIC) study.

METHODS AND RESULTS: In 6359 participants (mean age …


Evaluating The Military Medical Evacuation Dispatching And Delivery Problem Via Simulation And Self-Exciting Hawkes Process, Virbon B. Frial Mar 2022

Evaluating The Military Medical Evacuation Dispatching And Delivery Problem Via Simulation And Self-Exciting Hawkes Process, Virbon B. Frial

Theses and Dissertations

The location, allocation, and utilization of military medical evacuation (MEDEVAC) resources significantly impact the quality and timeliness of medical care to injured troops. In 2009, Secretary of Defense Robert Gates introduced the Golden Hour mandate that entails the evacuation of critically-injured troops to military treatment facilities (MTFs) within an hour to prevent further complications. To develop high-quality policies that improve MEDEVAC system performance, several papers in the current literature assume that MTFs have both the capacity and capability of treating any patient, regardless of the type of injury. However, these assumptions are unrealistic when conducting high-intensity operations. While acknowledging MTF …


The 2025 Michigan State Oral Health Plan, Ellen Sugrue Hyman Jd Mar 2022

The 2025 Michigan State Oral Health Plan, Ellen Sugrue Hyman Jd

The Journal of the Michigan Dental Association

This feature article explores the 2025 Michigan State Oral Health Plan (SOHP), a comprehensive initiative developed by the Michigan Oral Health Coalition (MOHC) and a statewide coalition, including the Michigan Dental Association (MDA). With a focus on enhancing oral health for all Michigan residents, the SOHP prioritizes addressing economic and racial disparities. The plan, guided by three key goals—Increasing Awareness and Education, Dental-Health Integration, and Access and Infrastructure—aims to improve oral health outcomes. The article discusses the plan's development process, key findings highlighting existing disparities, workforce challenges, and the strategic implementation of the SOHP through collaborative efforts and workgroups.


A Call For An Integrated Approach To Improve Efficiency, Equity And Sustainability In Rare Disease Research In The United States, Meghan C Halley, Hadley Stevens Smith, Euan A Ashley, Aaron J Goldenberg, Holly K Tabor Mar 2022

A Call For An Integrated Approach To Improve Efficiency, Equity And Sustainability In Rare Disease Research In The United States, Meghan C Halley, Hadley Stevens Smith, Euan A Ashley, Aaron J Goldenberg, Holly K Tabor

Faculty, Staff and Students Publications

To build a more efficient, equitable, and sustainable approach to rare disease research in the United States, we must prioritize integrated research infrastructure and approaches that focus on understanding connections across rare diseases.


Consumption Of Sugar-Sweetened Beverages And Its Potential Health Implications In Indonesia, Ratu Ayu D. Sartika, Atmarita Atmarita, M. I Zulkarnain Duki, Saptawati Bardosono, Lindawati Wibowo, Widjaja Lukito Feb 2022

Consumption Of Sugar-Sweetened Beverages And Its Potential Health Implications In Indonesia, Ratu Ayu D. Sartika, Atmarita Atmarita, M. I Zulkarnain Duki, Saptawati Bardosono, Lindawati Wibowo, Widjaja Lukito

Kesmas

The broad availability of sugar-sweetened beverages (SSBs) in the Indonesian market is increasing consumption. It, combined with escalating incidence and prevalence of diabetes and related non-communicable diseases (NCDs), and the ongoing debate on policies, has called for a comprehensive review as described in this study. Data was compiled from various sources but mainly gathered from the reported or published documents because of no direct access to the necessary data set. The lack of studies that assessed the direct relationship between SSB consumption and health outcomes in the Indonesian context also became a strong reason for the preparation of this review …


Body Image, Quality Of Life, And Their Predicting Factors In Pregnant Women: A Cross-Sectional Study, Zeynab Rezaei Fard, Arman Azadi, Yousef Veisani Feb 2022

Body Image, Quality Of Life, And Their Predicting Factors In Pregnant Women: A Cross-Sectional Study, Zeynab Rezaei Fard, Arman Azadi, Yousef Veisani

Kesmas

Pregnancy can influence women’s psychological health, including body image and quality of life. This study aimed to examine the relationship between body image and quality of life and their predicting factors in pregnant women. This cross-sectional study was conducted on 250 pregnant women referred to health centers in Ilam City, Iran. Participants were selected using a random sampling method. Data collection tools comprised a sociodemographic questionnaire, Body Image Concern Inventory (BICI), and quality of life questionnaire (Short Form-12). Data were analyzed using statistical software. The mean ± SD of body image concern and quality of life was estimated at 31.77 …


The Development Of A Work Stress Model For Air Traffic Controllers In Indonesia, Lalu Muhammad Saleh, Syamsiar Siang Russeng, Istiana Tadjuddin, Iva Hardi Yanti, Nurul Mawaddah Syafitri, Mahfuddin Yusbud, Yulianah Rahmadani Feb 2022

The Development Of A Work Stress Model For Air Traffic Controllers In Indonesia, Lalu Muhammad Saleh, Syamsiar Siang Russeng, Istiana Tadjuddin, Iva Hardi Yanti, Nurul Mawaddah Syafitri, Mahfuddin Yusbud, Yulianah Rahmadani

Kesmas

The workload complexity experienced by and expected air traffic controllers (ATCs) causes psychological fatigue, engenders stressful conditions, and affects their quality of life. This study investigated the development of a model of psychological fatigue in ATCs in Indonesia, which affected their work stress levels and quality of life. This cross-sectional, three-month study focused on 185 ATCs randomly selected from six AirNavs based on strata. The results indicated a relationship between work duration (p-value = 0.033) and stress on ATCs; additionally, a relationship between work time and the opportunity to meet personal life needs (p-value = 0.007) were found. Feelings of …


Effectiveness Of Using Information, Education, And Communication Flowchart Media In Implementation Of Early Breastfeeding Initiation, Rizna Notarianti, Sandra Fikawati, Alifani Faiz Faradhila Feb 2022

Effectiveness Of Using Information, Education, And Communication Flowchart Media In Implementation Of Early Breastfeeding Initiation, Rizna Notarianti, Sandra Fikawati, Alifani Faiz Faradhila

Kesmas

Early initiation of breastfeeding (EIB) has many benefits for both the baby and the mother. However, in Bogor City, there are still many babies who do not get EIB when they are born (33.6%). The implementation of EIB is not optimal due to the absence of standard procedures to equalize its theory and perception. This study aimed to investigate the effectiveness of using Information, Education, and Communication (IEC) flowchart media concerning the standard procedure for EIB implementation in the Primary Health Care (PHC) in Bogor City. A quasi-experimental research was conducted on 58 midwives divided into the intervention and control …


Aminolevulinic Acid Dehydratase Allelic Frequency And Lead Toxicity In Children Under-Five In A Former Used Lead-Acid Battery Area, Yana Irawati, Haryoto Kusnoputranto, Umar Fahmi Achmadi, Ahmad Safrudin, Alfred Sitorus, Rifqi Risandi, Suradi Wangsamuda, Dendi Hadi Permana, Lepa Syahrani, Farahana Kresno Dewayanti, Puji B S Asih, Din Syafruddin Feb 2022

Aminolevulinic Acid Dehydratase Allelic Frequency And Lead Toxicity In Children Under-Five In A Former Used Lead-Acid Battery Area, Yana Irawati, Haryoto Kusnoputranto, Umar Fahmi Achmadi, Ahmad Safrudin, Alfred Sitorus, Rifqi Risandi, Suradi Wangsamuda, Dendi Hadi Permana, Lepa Syahrani, Farahana Kresno Dewayanti, Puji B S Asih, Din Syafruddin

Kesmas

Polymorphisms in the Aminolevulinic Acid Dehydratase (ALAD) gene responsible for the ALAD1 and ALAD2 alleles have been implicated in susceptibility to lead toxicity. This study aimed to determine the allelic frequency of ALAD2 among children living in Bogor District, Indonesia, and its association with blood lead levels (BLLs) and lead toxicity. A cross-sectional study involving 128 children was conducted during September-October 2019 in the former ULAB area in Cinangka Village. The ALAD polymorphism, BLLs, and hematological parameters were evaluated. Blood samples were taken for dried blood spotting on filter paper, blood film, and BLL measurement. The PCR amplification and sequencing …