Public Health Commons^™

Association Between Self-Reported Fatigue And Sarcopenia Measures Among Elderly In Selangor, Malaysia, Maria Justine, Aliff Latir, Nadhirah Noor, Angelbeth Joanny, Izzaty Iskandar, Maisarah Sakinah Amirul Faizi, Dzulhelmi Edinan

Kesmas

The association between fatigue and sarcopenia is not well understood, therefore, this study aimed to compare the sarcopenia measures among elderly with mild and severe fatigue and to determine whether fatigue severity is associated with sarcopenia measures. This was a cross-sectional study conducted on201 elderly (age = 68.45±6.30 years). The elderly was classified into either mild or severe fatigue based on the Fatigue Severity Scale (FSS), meanwhile, sarcopenia measures include SARC-F score, muscle mass (ASM/height2), calf circumference (CC), upper (handgrip) and lower limb muscle strength, as well as physical performance (gait speed). Data were analyzed using independent t-tests and logistic …

Correlation Between Care Burden And Mental Health With The Perceived Social Support Of Patients Relatives In Turkey, Mehtap Şahi̇ngöz Tahta, Elçin Balci

Kesmas

The people providing care for relatives always need support and accompaniment from their families and friends. This study aimed to evaluate the correlation among the care burden, mental health and social support perceptions of the patients’ relatives that provide long-term care for patients receiving service from the home care service (HCS) unit in one city. This descriptive study was carried out with the relatives of patients receiving service from home health units. Among the relatives providing care for a total of 859 patients, those that did not comply with the inclusion criteria were excluded, which made a total population of …

Accelerating The Provision Of Safe Water Supply In Urban And Rural Areas Of Indonesia, Sumengen Sutomo, Salord Sagala, Bebi Sutomo, Sri Winarti, Gelant Sanjaya

Kesmas

Over the past 100 years, the provision of a safe water supply to drink in Indonesia has been slowly progressed with low coverage. The majority of the population does not have access to safe water. Morbidity and mortality of water-related diseases, including diarrhea, are very high. The provision of safe water is not a technological issue but good water management that comprises content, institutional, and communication layer. This paper provided information for strategic and operational decisions to accelerate the provision of safe water services in urban and rural areas. Benchmarking good water management with the characteristics of the water supply …

Strategy For Diagnosing Breast Cancer In Indonesia During The Covid-19 Pandemic: Switching To Ultrasound-Guided Percutaneous Core Needle Biopsy, Farida Briani Sobri, Adang Bachtiar, Sonar Soni Panigoro, Juwita Cresti Rahmaania, Patria Wardana Yuswar, Ening Krisnuhoni, Nelly Tandiari

Kesmas

In this era of COVID-19, suspected breast cancer patients experience delay in diagnosis due to the fear of contracting the virus and reduction of non-COVID-19 health services. Furthermore, it may lead to potential increase in the incidence of advanced cancers in the future. Ultrasound-guided (US-guided) percutaneous core needle biopsy (CNB) is a great option for the diagnosis of cancer but it is poorly utilized. This study aimed to prove that the US-guided CNBis accurate when performed in a local setting and a potential solution for diagnosing breast cancer patients in this pandemic. In addition, it was a single health center …

Correlation Between Dental Environment And Perceived Stress Scale Among Dental Students During The Covid-19 Pandemic In Indonesia, Tri Erri Astoeti, Howis Josephine, Armelia Sari Widyarman, Widijanto Sudhana

Kesmas

Academic stressors in a medical educational environment are related to two factors. This study was carried out in order to analyze the correlation between the dental environment and perceived stress among dental students during the COVID-19 pandemic. The respondents were 422 undergraduate dental students and the validated Modified Dental Environmental Stress (DES) and Perceived Stress Scale (PSS) questionnaires were used. Furthermore, the Spearman correlation analysis was used to measure the correlation between DES and PSS score. The result showed that five dental stressors were noted to have the strongest correlations with PSS (p-value >0.40). They include expectation towards dental school …

Characteristics Of Cognitive Status In Sub-Population Of Sub-Acute Stage Of Ischemic Stroke Patients In West Nusa Tenggara, Indonesia, Herpan Syafii Harahap, Muhammad Akbar, Jumraini Tammasse, Andi Kurnia Bintang, Andi Alfian Zainuddin

Kesmas

Cognitive decline is a significant complication that affects most stroke survivors. Early detection of cognitive decline in ischemic stroke patients and identification of risk factors improves their clinical outcomes. This study aimed to determine the characteristics of cognitive status in the sub-acute phase of ischemic stroke. A cross-sectional study was conducted on 89 sub-acute ischemic stroke patients in three hospitals in West Nusa Tenggara recruited consecutively from August 2019 to April 2020. The data collected were demographic and clinical characteristics, cognitive status, and functional outcome. The association between clinical and demographic characteristics and cognitive decline was analyzed using logistic regression. …

King Bhumibol Adulyadej’S Sufficiency Economy Philosophy And Post-Traumatic Stress Disorder Among Higher-Education Students From The Armed Conflict Region Of Thailand, Chonnakarn Jatchavala, Arnont Vittayanont

Kesmas

This cross-sectional survey assessed the association between post-traumatic stress disorder symptoms and perceived self-sufficiency, reflecting the Sufficiency Economy Philosophy (SEP), conceived by H.M. King Bhumibol Adulyadej (King Rama IX). It was conducted among university students on one campus located within the area affected by the Southern Thailand insurgency and another campus located in a nearby province outside of the restive area. All self-administered questionnaires consisted of questions related to personal information, the Thai version of the PTSD checklist, and a questionnaire aimed at measuring the perceived self-sufficiency according to H.M. King Bhumibol Adulyadej’s SEP. The study found that most university …

Covid-19 Preparedness And The Anxiety Of Thai Citizens, Afifi Lateh, Prasopchai Pasunon, Kiflan Dolah, Panida Kongjam, Saminee Chemae, Phanupong Panomwan, Alawee Lateh

Kesmas

The outbreak of COVID-19 has brought sickness and fatality to Thai citizens. In addition, it left a tremendous psychological impact on mental health as they experienced panic and anxiety about controlling situations and preserving their physical and mental well-being. This study aimed to analyze the factors influencing COVID-19 preparedness and anxiety based on groups of Thai citizens. Online questionnaires were employed to collect data from 2,768 respondents selected through convenience sampling and snowball sampling on Facebook, having shared questionnaires with 190 other users. Data were collected from March 29 to April 3, 2020. The acquired data were analyzed using percentage …

A Convergent Parallel Study On Knowledge, Perceptions, And Attitudes Of Mainstream Workers During Covid-19, Farhan Alshammari, Romeo Mostoles Jr, Eddieson Pasay-An, Sultan Alshammari

Makara Journal of Health Research

Background: This study explores and assesses the knowledge, perceptions, and attitudes of mainstream workers during the COVID-19 pandemic in the Ha’il Region, Kingdom of Saudi Arabia.

Methods: Using convergent parallel mixed-methods design, 502 frontline workers were enlisted via snowball and purposive sampling. Descriptive statistics and thematic analysis were used to analyze the quantitative and qualitative data, respectively.

Results: There is a well-prepared response to COVID-19, namely, a commendable knowledge, attitude, and practices (KAP) gap documented in reliable information concerning the virus, specifically, awareness that COVID-19 can be a potentially fatal disease (100%); that droplets from infected people …

Genetic Testing Reveals Germline Mutations Among Patients Undergoing Surgery For Colorectal Carcinoma In A Community Hospital Setting, Alex R. Jones, Dana Greer Rn, Bsn, Ocn, Karin L. Cole Md

Journal of Maine Medical Center

Introduction: Defined germline mutations contribute to 5% to 10% of cases of colorectal carcinoma (CRC). While protocols for universal tumor screening have been adopted to detect mismatch repair (MMR) protein deficiency, widespread multigene panel testing has not been achieved. Barriers to implementing testing protocols may occur in community settings.

Methods: A total of 160 patients presenting for surgical management of CRC between 2011 and 2020 were considered for retrospective analysis in a single-surgeon, single-institution, community-based cohort. The rate of multigene panel testing and prevalence of germline mutations were calculated, and patient characteristics were assessed.

Results: A total of 32/160 (20%) …

County And Demographic Differences In Drug Arrests And Controlled Substance Use In Maine, Trajan F. Hyde, Amadea D. Bekoe-Tabiri, Amalie K. Kropp Lopez, Luis G. Devia, Belsy D. Gutierrez, Matthew C. Lara, Anthony R. Soto, Daniel E. Kaufman, Matthew T. Moran, Kevin J. Simpson, Dipam T. Shah, Michelle Foster, Clare E. Desrosiers, John Hebert, Stephanie D. Nichols, Kenneth Lee Mccall, Brian J. Piper

Journal of Maine Medical Center

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Introduction: The Diversion Alert Program (DAP) was established to curb misuse of drugs and help identify people who may need treatment for substance use disorder (SUD). Law enforcement compiled arrest data into a database accessible by health care providers. Our objectives were to identify regional and demographic differences in drug use and misuse in Maine.

Methods: All arrests (N = 11 234) reported to the DAP from 2013 to 2018 were examined by county and arrestee demographics, and classified into families (opioids, stimulants, sedatives). The Drug Enforcement Administration’s Automation of Reports and Consolidated Orders System (ARCOS) tracks the distribution …

Use Of Internet Platforms For Information About Sensitive Teeth Among Indonesian Adults: A Cross-Sectional Study, Safira Khairina, Diah Ayu Maharani, Yasemin Yavuz, Febriana Setiawati

Makara Journal of Health Research

Background: The behavior of seeking oral health information (OHI), especially the topic of sensitive teeth (ST), among the Indonesian adult population has rarely been studied. Hence, the current work aimed to analyze the characteristics of the Indonesian adult population who reported having ST and to explore their practice of self-medication in terms of their behavior of seeking OHI on the internet.

Methods: A cross-sectional study was conducted between January and March 2021 in Indonesia. This study used a self-administered questionnaire comprising questions about sociodemographic data, oral health behavior, diet, and subjective oral health. Bivariate analysis based on a …

Preventive Behaviors, Barriers, And Drivers Of The Covid-19 Pandemic In Malaysia: A Cross-Sectional Survey, Normaliza Ab Malik, Rusyda Helma Mohd, Nor Ba'yah Abdul Kadir

Makara Journal of Health Research

Background: Coronavirus disease 2019 (COVID-19) is a public health concern worldwide. This study aimed to assess the preventive behaviors, barriers, and drivers, including the knowledge and self-efficacy of COVID-19 in Malaysia.

Methods: A cross-sectional study was conducted during the COVID-19 outbreak by using a self-administered questionnaire. The instrument used was adopted from the World Health Organization resources. Descriptive statistics were used to describe the categorical data. Chi-square and independent t-test were performed to evaluate the associations between the variables and preventive behaviors.

Results: A total of 465 (97.3%) respondents were recorded. The mean age was 34.3 ± …

Determination Of The Nutritional Habits And Anxiety Levels In Individuals With Covid-19 In Turkey, Hatice Iskender, Eda Dokumacioglu, Osman Yalap

Makara Journal of Health Research

Background: Coronavirus disease 2019 (COVID-19), which has spread worldwide since December 2019, has infected and claimed the lives of millions of people. This study aimed to investigate the relationship between anxiety levels and nutritional habits of patients with COVID-19.

Methods: This cross-sectional study enrolled patients diagnosed with COVID-19 between February 1, 2021 and May 1, 2021. The study population included a total of 108 individuals with COVID-19 residing in Artvin, Turkey. This study used a self-administered online questionnaire, containing 40 questions from the State and Trait Anxiety Scale.

Results: The state anxiety score was 37.26, and the …

Loneliness And Health Outcomes Among Malaysian Older Adults, Siti Zuhaida Hussein, Azera Hasra Ismail, Suraya Hanim Abu Bakar

Makara Journal of Health Research

Background: Loneliness is a major social problem among the elderly all over the world.

Methods: A community-based survey was conducted among 380 community-dwelling older adults residing in Malaysia. A proportional stratified random sampling method was used to examine the relationship between health factors and loneliness. Data were collected using the short-form Social and Emotional Loneliness Scale for Adults, Geriatric Depression Scale-15, and RAND SF-20. p < 0.05 was considered to be statistically significant, and data analysis was performed using Statistical Package for the Social Sciences Statistics 26.0 for Windows.

Results: Results revealed that 32.6% of the respondents had social loneliness, 39.9% had emotional loneliness, and 9.2% had family loneliness. Bivariate analyses showed that social and emotional loneliness are significantly related to …

Prevalence And Correlates Of Frequent And Infrequent Bullying Victimization Among School Adolescents From Five Southeast Asian Countries, Karl Peltzer, Supa Pengpid

Makara Journal of Health Research

Background: Little is known about the frequency of bullying victimization (BV) among adolescents in Association of Southeast Asian Nations (ASEAN) member states. This study aims to assess the prevalence and correlates of frequent and infrequent BV among school-going adolescents in five ASEAN member states.

Methods: The cross-sectional sample of the Global School-based Student Health Survey (GSHS) of 2015 comprised 33,184 school adolescents (14.6 years mean age) from five ASEAN countries. Students completed a paper-based, self-administered questionnaire on BV in their own languages during classroom periods. Multinomial logistic regression was used to predict frequent and infrequent BV, with no …

Patient Care Delivery: Electronic Nursing Documentation In Malaysia, Siti Zuhaida Hussein, Norazilah Khalip, Rosnita Hashim, Rohaizah Harun, Nor Fazlina Fazilah, Norazilah Mat Shah

Makara Journal of Health Research

Background: The evolution of nursing documentation from paper to electronic format aims to improve patient safety and care quality. This study aimed to determine the knowledge and attitudes of registered nurses toward electronic nursing process documentation.

Methods: This cross-sectional study was conducted among 189 registered nurses who work in medical wards at a teaching hospital in Kuala Lumpur. Simple random sampling was used. Respondents’ knowledge of electronic nursing documentation was measured using a questionnaire developed by Guedes, and their attitudes toward electronic nursing documentation were measured using a questionnaire developed by Hagos. Data analysis was performed using Statistical …

Disparities In Covid-19 Rates Among Various Demographics And Lack Of Racial Representation In Medical Texts, Diangelo Gonzalez

Celebration of Learning

The 2019 novel coronavirus (COVID-19) outbreak, which originated in Wuhan, China in December of 2019, has impacted nations all over the globe. Given the health disparities which existed within the United States prior to the COVID-19 pandemic, this pandemic continued to pose a significant challenge to the health of the public. The aims of this research study were twofold: (1) to analyze the incidence rates of COVID-19 among different racial and ethnic groups within the United States and (2) to describe the occurrence of diversity within medical texts. Overall, the COVID-19 pandemic exacerbated health disparities within the United States. Understanding …

Why Should People Use Face Masks In The Time Of Covid? The Jri Position, Jose Bordon, Alex Glynn, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Cohort Profile: The Alliance For Maternal And Newborn Health Improvement (Amanhi) Biobanking Study, Fahad Aftab, Salahuddin Ahmed, Aneeta Hotwani, Muhammad Ilyas, Mohammad Javaid, Fyezah Jehan, Farah Khalid, Usma Mehmood, Muhammad Imran Nisar, Muhammad Sajid

Department of Paediatrics and Child Health

No abstract provided.

Apobec Mutagenesis Is Concordant Between Tumor And Viral Genomes In Hpv-Positive Head And Neck Squamous Cell Carcinoma, Daniel L. Faden, Krystle A. Lang Kuhs, Maoxuan Lin, Adam Langenbucher, Maisa Pinheiro, Meredith Yeager, Michael Cullen, Joseph F. Boland, Mia Steinberg, Sara Bass, James S. Lewis, Michael S. Lawrence, Robert L. Ferris, Lisa Mirabello

Epidemiology and Environmental Health Faculty Publications

APOBEC is a mutagenic source in human papillomavirus (HPV)-mediated malignancies, including HPV+ oropharyngeal squamous cell carcinoma (HPV + OPSCC), and in HPV genomes. It is unknown why APOBEC mutations predominate in HPV + OPSCC, or if the APOBEC-induced mutations observed in both human cancers and HPV genomes are directly linked. We performed sequencing of host somatic exomes, transcriptomes, and HPV16 genomes from 79 HPV + OPSCC samples, quantifying APOBEC mutational burden and activity in both host and virus. APOBEC was the dominant mutational signature in somatic exomes. In viral genomes, there was a mean of five (range 0–29) mutations per …

No Difference In Clinical Outcomes For African American And White Patients Hospitalized With Sars-Cov-2 Pneumonia In Louisville, Kentucky, Julio A. Ramirez, Stephen P. Furmanek, Thomas Chandler, Stephen S. Hanson, Dawn Balcom, Subathra Marimuthu, Sathya Krishnasamy, Jose Bordon, Rodrigo Cavallazzi, Amr Aboelnasr, Mahder A. Tella, William A. Mattingly, Ashley M. Wilde, Daisy Sangroula, Demetra Antimisiaris, Donghoon Chung, Guillermo Cabral, Gabino R Fernandez-Botran, Jiapeng Huang, Martin Gnoni, Ozan Akca, Paul Schulz, Phillip F. Bressoud, Priya Krishnan, Sally Suliman, William P. Mckinney, Bryan Moffett, Leslie A Wolf, Mark Burns, Alex Glynn, Ruth Carrico, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

Introduction: Current literature indicates that African American individuals are at increased risk of becoming infected with the SARS-CoV-2 virus and suffer higher SARS-CoV-2-related mortality rates. However, there is a lack of consensus as to how the clinical outcomes of African American patients differ from those of other groups. The objective of this study was to define the clinical outcomes of African American and White hospitalized patients with SARS-CoV-2 community-acquired pneumonia (CAP) in Louisville, Kentucky.

Methods: This was a retrospective cohort study of hospitalized patients with SARS-CoV-2 CAP at eight hospitals in Louisville, Kentucky. Severity of CAP at time of hospitalization …

Strongyloides Stercoralis Hyperinfection And Disseminated Tuberculosis, Hernan Terroba, Alejandra González, Diana Vera Gonzalez, Roxana Mariela Godoy, Analia Santos, Marisol Arrojo

The University of Louisville Journal of Respiratory Infections

No abstract provided.

The Histories Of Hivs : The Emergence Of The Multiple Viruses That Caused The Aids Epidemics, William H. Schneider

Ohio University Press Open Access Books

This new collection of essays on HIV viruses spans disciplines to topple popular narratives about the origins of the AIDS pandemic and the impact of the disease on public health policy.

With a death toll in the tens of millions, the AIDS pandemic was one of the worst medical disasters of the past century. The disease was identified in 1981, at the height of miraculous postwar medical achievements, including effective antibiotics, breakthrough advances in heart surgery and transplantations, and cheap, safe vaccines—smallpox had been eradicated just a few years earlier. Arriving as they did during this era of confidence in …

Testing Testimonial., Jason Beiriger, David B. Nash

College of Population Health Faculty Papers

No abstract provided.

Chagas Disease In Hiv-Infected Patients: It’S Time To Consider The Diagnosis, Melissa Nolan Ph.D., Mph, Natasha S. Hochberg

Faculty Publications

No abstract provided.

Effect Of An Antenatal Lifestyle Intervention On Dietary Inflammatory Index And Its Associations With Maternal And Fetal Outcomes: A Secondary Analysis Of The Pears Trial, Sarah Louise Killen, Catherine M. Phillips, Anna Delahunt, Cara A. Yelverton, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Maria A. Kennelly, Martina Cronin, John Mehegan, Fionnuala M. Mcauliffe

Faculty Publications

We investigated the effect of an antenatal lifestyle intervention of a low-glycaemic index (GI) diet and physical activity on energy-adjusted dietary inflammatory index (E-DIITM) and explored its relationship with maternal and child health in women with overweight and obesity. This was a secondary analysis of 434 mother−child pairs from the Pregnancy Exercise and Nutrition Study (PEARS) trial in Dublin, Ireland. E-DII^TM scores were calculated for early (10–16 weeks) and late (28 weeks) pregnancy. Outcomes included lipids, inflammation markers, insulin resistance, mode of delivery, infant size, pre-eclampsia, and gestational diabetes. T-tests were used to assess changes in E-DII^TM. …

Increasing Public Health Mosquito Surveillance In Hidalgo County, Texas To Monitor Vector And Arboviral Presence, Clarissa D. Guerrero, Steven Hinojosa, Diana Vanegas, Niko Tapangan, Matthew Guajardo, Sara Alaniz, Narda Cano, Christopher Vitek, John M. Thomas, Valerie Hernandez, Juan Garcia Jr.

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

From 2016 to 2018, Hidalgo County observed the emergence of Zika virus (ZIKV) infections along with sporadic cases of Dengue virus (DENV) and West Nile virus (WNV). Due to the emergence of ZIKV and the historical presence of other mosquito-borne illnesses, Hidalgo County obtained funding to enhance mosquito surveillance and educate residents on arboviruses and travel risks. During this time period, Hidalgo County mosquito surveillance efforts increased by 1.275%. This increase resulted in >8000 mosquitoes collected, and 28 mosquito species identified. Aedes aegypti, Ae albopictus and Culex quinquefasciatus made up approximately two-thirds of the mosquitoes collected in 2018 (4122/6171). Spatiotemporal …

The Increasing Role Of Pragmatic Clinical Trials And Real-World Data In Healthcare Research, Julio A. Ramirez, Ruth Carrico

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Roles Of A Bradykinin Storm And A Cytokine Storm In Covid-19 Cases, Nouha H. Odeh

Honors College Theses

In the light of recent events, it is imperative to understand the key inflammatory response elements that appear to be the source of more severe ailments resulting from a SARS-CoV-2 viral infection known as Covid-19 The more severe cases of Covid-19 are characterized by a severe inflammatory response resulting in tissue damage. My research proposal aims to investigate the two possible culprits of this response: a bradykinin (BK) storm and an interleukin-6 (IL-6) mediated cytokine storm. In both systems respectively, the excess release of these signals subsequently signals the production of even more of the same response element, resulting in …