Open Access. Powered by Scholars. Published by Universities.®

Neuroscience

Discipline
Institution
Publication Year
Publication
Publication Type

Articles 1 - 10 of 10

Full-Text Articles in Other Psychiatry and Psychology

Psychedelic Psychotherapy And The Mental Health Crisis: A Historical And Scientific Review, Dylan Kunkel, Neil Levens, Charles Schumpert Apr 2025

Psychedelic Psychotherapy And The Mental Health Crisis: A Historical And Scientific Review, Dylan Kunkel, Neil Levens, Charles Schumpert

Senior Theses

The global mental health crisis continues to expose the limitations of traditional psychiatric treatments for major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). As conventional antidepressants offer modest remission rates and delayed efficacy, interest has grown in the therapeutic potential of psychedelic compounds. This thesis explores psychedelic psychotherapy through both a historical and scientific lens, tracing its roots from ancient ceremonial practices to modern clinical trials. It also provides context behind the neurobiological mechanisms by which psychedelics like psilocybin, LSD, ketamine, MDMA, and DMT affect mood and cognition. These compounds appear to reduce default mode network (DMN) connectivity, increase …


The Image Of Schizophrenia In Spain's Healthcare System, Meghan Webb Jan 2024

The Image Of Schizophrenia In Spain's Healthcare System, Meghan Webb

CISLA Senior Integrative Projects

Schizophrenia affects thousands of people in Spain and is one of the most serious mental health disorders in existence. Despite its this characteristic, schizophrenia did not always get the proper attention it deserved within the country’s healthcare system. This was largely due to the influence that the Spanish government had, and continues to have, over the healthcare system, giving it the power to choose how the disorder was represented. Therefore, what does that mean for schizophrenia in Spain’s healthcare system today? This essay will explore the ways in which schizophrenia was represented in Spain’s healthcare system through an examination of …


Role Of Nucleus Accumbens Dopamine Receptor Signaling In The Suppression Of Punished Reward Seeking, Grace M. Joyner, Anna Caroline Toburen Apr 2023

Role Of Nucleus Accumbens Dopamine Receptor Signaling In The Suppression Of Punished Reward Seeking, Grace M. Joyner, Anna Caroline Toburen

Senior Theses

Previous studies have shown that within the nucleus accumbens (NAc), a brain region associated with motivation and reinforcement learning, activity of neurons expressing the dopamine D2 receptor (D2R neurons) act as a “break” on risky behavior associated with negative outcomes. Moreover, when these neurons are stimulated, rats were found to become more risk averse. However, the impact of dopamine signaling through NAc D2R neurons in risk avoidance is still unclear. To further explore the role of NAc dopamine signaling in punished reward-seeking, we tested rats in a novel punished food-seeking paradigm in which subjects are trained to choose between a …


The Role Of The Nlrp3 Inflammasome In Alzheimer's Disease, Ethan S. Terman Jan 2023

The Role Of The Nlrp3 Inflammasome In Alzheimer's Disease, Ethan S. Terman

Undergraduate Research Posters

This study examines the consequences of Alzheimer’s in rat and mice test subjects. The goal is to identify the effects of certain NLRP3 inhibiting drugs and to see if there are any noticeable effects in regards to impeding the pathological development of Alzheimer’s disease. The results are visualized by implementing the immunohistochemical process to identify neurodegeneration in the brain and to assess the expression levels of amyloid beta as an indicator of Alzheimer’s pathology. Other tests are also conducted on these transgenic mice to gauge cognitive functioning levels during the onset of their disease, those being behavior tests, but not …


Multilingualism And Memory: Investigating Possible Differences In The Abilities Of Monolingual And Multilingual College Students, Clara E. Barned Dec 2022

Multilingualism And Memory: Investigating Possible Differences In The Abilities Of Monolingual And Multilingual College Students, Clara E. Barned

Honors Projects

This study investigated whether there is a difference in the memories of monolingual and multilingual undergraduate students using simple memorization tasks. There were 46 participants, 30 of which were monolingual (only knew one language) and 16 of which were multilingual (knew two or more languages). There was found to be no significant difference between the performance of the two groups, with the data generating a p-value of 0.557. This study further suggests related avenues of research and ways in which the study could be improved in the future.


Emotion And Cognition Analysis Of Intro And Senior Cs Students In Software Engineering, Justin Evans Jun 2021

Emotion And Cognition Analysis Of Intro And Senior Cs Students In Software Engineering, Justin Evans

Master's Theses

he software engineering community has advanced the field in the past few decades towards making the software development life cycle more efficient, robust, and streamlined. Advances such as better integrated development environments and agile workflows have made the process more efficient as well as more flexible. Despite these many achievements software engineers still spend a great deal of time writing, reading and reviewing code. These tasks require a lot of attention from the engineer with many different variables affecting the performance of the tasks. In recent years many researchers have come to investigate how emotion and the way we think …


Understanding The Traumatized Brain, Sam Marion, Elizabeth Marston Mar 2021

Understanding The Traumatized Brain, Sam Marion, Elizabeth Marston

National Youth Advocacy & Resilience Conference

Students who have experienced trauma are often in need of behavioral intervention due to challenging behaviors and reactivity. Understanding the body’s threat response system gives insight into these behaviors and allows for empathy within the interventions. This presentation will outline basic neuroscience theories, propose interventions focused on self-regulation, and demonstrate how adding basic elements to existing interventions can increase efficacy.


Measuring Neural Time Series Data In A Sensory Deprivation Tank, Jackson Gregory, Tian Lan, Uri Maoz, Amir Raz May 2019

Measuring Neural Time Series Data In A Sensory Deprivation Tank, Jackson Gregory, Tian Lan, Uri Maoz, Amir Raz

Student Scholar Symposium Abstracts and Posters

We are interested in studying the neurological and physiological effects of the float pod, also known as REST therapy, or sensory deprivation tank. Float pods rely on the concept of depriving most senses (from sound and light to temperature and proprioception) in a pool filled with buoyant salt water at body temperature. While float pods are most commonly used in spa environments, we intend to look at the potential benefits of floating under the empirical lens. In this study, we aim to measure neural activity using electroencephalography (EEG). We intend to look at the different levels of relaxation and the …


Novel Biomarkers Of Physical Activity Maintenance In Midlife Women: Preliminary Investigation, Kelly A. Bosak, Vlad B. Papa, Morgan G. Brucks, Cary R. Savage, Joseph E. Donnelly, Laura E. Martin Jan 2018

Novel Biomarkers Of Physical Activity Maintenance In Midlife Women: Preliminary Investigation, Kelly A. Bosak, Vlad B. Papa, Morgan G. Brucks, Cary R. Savage, Joseph E. Donnelly, Laura E. Martin

Center for Brain, Biology, and Behavior: Faculty Publications

The precision health initiative is leading the discovery of novel biomarkers as important indicators of biological processes or responses to behavior, such as physical activity. Neural biomarkers identified by magnetic resonance imaging (MRI) hold promise to inform future research, and ultimately, for transfer to the clinical setting to optimize health outcomes. This study investigated resting-state and functional brain biomarkers between midlife women who were maintaining physical activity in accordance with the current national guidelines and previously acquired age-matched sedentary controls. Approval was obtained from the Human Subjects Committee. Participants included nondiabetic, healthy weight to overweight (body mass index 19–29.9 kg/m …


Minimal Information For Neural Electromagnetic Ontologies (Minemo): A Standards-Compliant Method For Analysis And Integration Of Event-Related Potentials (Erp) Data, Gwen Frishkoff, Jason Sydes, Kurt Mueller, Tim Curran, John F. Connolly, Kerry Kilborn, Dennis L. Molfese, Charles Perfetti, Allen D. Malony Jan 2011

Minimal Information For Neural Electromagnetic Ontologies (Minemo): A Standards-Compliant Method For Analysis And Integration Of Event-Related Potentials (Erp) Data, Gwen Frishkoff, Jason Sydes, Kurt Mueller, Tim Curran, John F. Connolly, Kerry Kilborn, Dennis L. Molfese, Charles Perfetti, Allen D. Malony

Center for Brain, Biology, and Behavior: Faculty Publications

We present MINEMO (Minimal Information for Neural ElectroMagnetic Ontologies), a checklist for the description of event-related potentials (ERP) studies. MINEMO extends MINI (Minimal Information for Neuroscience Investigations)to the ERP domain. Checklist terms are explicated in NEMO, a formal ontology that is designed to support ERP data sharing and integration. MINEMO is also linked to an ERP database and web application (the NEMO portal). Users upload their data and enter MINEMO information through the portal. The database then stores these entries in RDF (Resource Description Framework), along with summary metrics, i.e., spatial and temporal metadata. Together these spatial, temporal, and functional …