Behavior and Behavior Mechanisms Commons^™

The Effects Of Two Novel Anti-Inflammatory Compounds On Prepulse Inhibition And Neural Microglia Cell Activation In A Rodent Model Of Schizophrenia, Heath W. Shelton

Electronic Theses and Dissertations

Recent studies have shown elevated neuroinflammation in a large subset of individuals diagnosed with schizophrenia. A pro-inflammatory cytokine, tumor necrosis factor-alpha (TNFα), has been directly linked to this neuroinflammation. This study examined the effects of two TNFα modulators (PD2024 and PD340) produced by our collaborators at P2D Bioscience, Inc., to alleviate auditory sensorimotor gating deficits and reduce microglial cell activation present in the polyinosinic:polycytidylic (Poly I:C) rodent model of schizophrenia. Auditory sensorimotor gating was assessed using prepulse inhibition and microglial activation was examined and quantified using immunohistochemistry and confocal microscopy, respectively. Both PD2024 and PD340 alleviated auditory sensorimotor gating deficits …

Associations Of First Trimester Co-Use Of Tobacco And Cannabis With Prenatal Immune Response And Psychosocial Well-Being, Kristin Ashford, Amanda Fallin-Bennett, Andrea Mccubbin, Amanda T. Wiggins, Sheila Barnhart, Joshua A. Lile

Perinatal Research and Wellness Center Faculty Publications

PURPOSE: This study aims to describe the association of first trimester co-use of tobacco and cannabis with maternal immune response and psychosocial well-being, relative to tobacco use only.

METHODS: A preliminary midpoint analysis included 138 pregnant women with biologically verified tobacco use, 38 of whom (28%) also tested positive for recent cannabis use. Maternal perceived stress (Perceived Stress Scale), depressive symptoms (Edinburgh Postnatal Depression Scale), and serum immune markers (IL-1β, IL-2, IL-6, IL-8, IL-10, TNFα, CRP, MMP8), were collected, although cytokine data were only available for 122 women.

RESULTS: Participant average age was 29.1 years, approximately half had a high …

Measuring Neural Time Series Data In A Sensory Deprivation Tank, Jackson Gregory, Tian Lan, Uri Maoz, Amir Raz

Student Scholar Symposium Abstracts and Posters

We are interested in studying the neurological and physiological effects of the float pod, also known as REST therapy, or sensory deprivation tank. Float pods rely on the concept of depriving most senses (from sound and light to temperature and proprioception) in a pool filled with buoyant salt water at body temperature. While float pods are most commonly used in spa environments, we intend to look at the potential benefits of floating under the empirical lens. In this study, we aim to measure neural activity using electroencephalography (EEG). We intend to look at the different levels of relaxation and the …

Delay Discount Rate Moderates A Physical Activity Intervention Testing Immediate Rewards, Christine B. Phillips, Jane C. Hurley, Siddhartha S. Angadi, Michael Todd, Vincent Berardi, Melbourne Hovell, Marc A. Adams

Psychology Faculty Articles and Research

Financial incentives can increase physical activity (PA), but differences in the immediacy of reward delivery and individual differences in delay discount rates (i.e., higher discount values associated with less tolerance for delayed rewards) may explain differential responding. The current study tested whether delay discount rate moderated the relative effectiveness of immediate financial rewards on increasing daily PA. Inactive, overweight adults (ages 18–60, N = 96) were randomized to receive either smaller, immediate goal-contingent rewards or larger, delayed rewards for participation. Delay discount rates were derived for those who completed the Monetary Choice Questionnaire (N = 85). Linear mixed models tested …

The Influence Of Stressful Life Events On The Development Of Type 2 Diabetes, Joshua Minks

Dissertations

This study examined the relationship between distress and the development of Type 2 diabetes mellitus (T2DM) in the presence of established risk factors. Distress secondary to mental health disparities, stressful life events, and work conditions has been shown to promote insulin resistance and the development of T2DM.

Subjects (N=79) diagnosed with T2DM within the previous six months were recruited from SSM Health Centers and VA Medical Centers in the greater St. Louis area. They completed the Recent Life Changes Questionnaire, ENRICHD Social Support Instrument, and a demographic survey and analyses were conducted to determine differences between the veteran …

What Is An Extinction Burst?, Kristal Huffman

Capstone Projects

Abstract

This paper will explore the effects of extinction, specifically the extinction burst. Extinction is known to be an effective and necessary process in decreasing specific behaviors (Iwata, Pace, Kalsher, Cowdery, & Cataldo, 1990). During this process, side effects might occur and the extinction burst is one of those side effects. Extinction bursts might be a problematic side effect, especially during treatment of severe behavior. This paper will explore the extinction burst in detail as well as how the term is used in both the basic and applied literature. Next, an investigation of the extinction burst as a technical term …

Longitudinal Effects Of Maternal Love Withdrawal And Guilt Induction On Chinese American Preschoolers’ Bullying Aggressive Behavior, Jing Yu, Charissa S.L. Cheah, Craig H. Hart, Chongming Yang, Joseph A. Olsen

Faculty Publications

Bullying has been understudied among preschool children, especially those from Chinese American families. Previous research has also neglected the dimensional effects of psychological control on child bullying development. This study examined two psychological control dimensions, love withdrawal and guilt induction, and their effects on children’s bullying aggressive behavior using a longitudinal design. Participants were first generation Chinese American mothers (N = 133;mean age [Mage] = 37.82) and their preschool children (Mage = 4.48). Chinese immigrant mothers reported their psychologically controlling parenting and teachers rated children’s bullying aggressive behaviors in the school setting. Confirmatory factor analyses were conducted to establish the …

Anxiety-Like Behavior In Adolescent Rats Following Maternal Separation And Chronic Cocaine Exposure, Jonathan Handy

Behavioral Neuroscience Honors Papers

Cocaine is one of the most widely used illicit substances in the world and has an addiction rate comparable to opioids. Early Life Stress (ELS) has been shown to have a profound influence on the development of an individual, showing strong correlations to the development of psychiatric disorders and psychostimulant abuse. Adolescents in particular are at a high risk for the abuse of psychostimulants such as cocaine. Previous studies have individually described the correlation between cocaine addiction and anxiety, and the correlation between ELS and cocaine addiction. Rats who have experienced some form of ELS have shown a higher levels …

Stress, Social Support, And Mindfulness In Parents Of Children With Neurodevelopmental Deficits: A Quantitative Analysis, Branden D. Syrotchen

Walden Dissertations and Doctoral Studies

Parenting children with neurodevelopmental deficits (NDDs) is very stressful, more so than the parenting of typically developing children. There is considerable research on the topic of chronic stress experienced by caregivers; however, less is understood of parental stress experienced when raising children with NDDs. The purpose of this study was to examine how parental traits and habits, in the forms of mindfulness and social support levels, affect this cohort's general stress levels. The study was guided by Self-Determination Theory, which explored how parental acts could be classified along a continuum of being intrinsically or extrinsically derived. A convenience sample of …

Differences Between Nontraditional And Traditional College Students' Perceptions Of Transition Preparedness, Laila Erika Turner

Walden Dissertations and Doctoral Studies

While scholars have used Schlossberg's transition theory for more than 35 years to study college-to-work transition, researchers have yet to establish if there are meaningful differences in the perceptions of traditional and nontraditional college students regarding transition preparedness from college-to-work. Following the career transition model, this quantitative study was conducted to compare traditional and nontraditional college students' perceptions of transition preparedness, specifically the concepts of readiness, confidence, control, perceived support, and decision independence. The nontraditional students in this study were military veterans. The dependent variables were measured by the Career Transition Inventory (CTI) survey. Participants were selected via a web-based …

The Lived Experiences Of Adult Male Trauma Survivors With Dance Movement Therapy, Jeanne Langston

Walden Dissertations and Doctoral Studies

In the United States, approximately 7.7 million individuals are affected by posttraumatic stress disorder (PTSD) at any given time. Though women are likelier to develop PTSD symptoms, men are exposed to more traumatic events in their lifetimes. Empirically- supported PTSD options exist, however clinical application of these treatments may not consistently culminate in beneficial outcomes. Dance Movement Therapy (DMT) has demonstrated positive treatment outcomes for a variety of mental and physical disorders. Nonetheless, there is a lack of robust research related to the treatment experiences of men who have participated in DMT for trauma-related symptoms. The purpose of this phenomenological …

Bet You Can’T Eat Just One: Binge Eating Disorder Promotion In American Food Advertising, Debbie Danowski

Communication, Media & The Arts Faculty Publications

"Eat Like Andy“; "What Would You Do For A Klondike Bar?“ For well over a century, American food manufacturers have been competing for consumers’ attention through the use of catchy jingles, iconic characters and celebrities. At the same time, the products being advertised contain greater amounts of addictive ingredients, which encourage binge eating resulting in an unprecedented obesity epidemic. Combine this with the full-scale commercialization of the culture today“. Jhally identifies and the powerful impact of food advertisements becomes clear as does the need to evaluate these ads. As Kilbourne noted nearly a quarter of a century ago, the majority …

Relations Among Maternal And Paternal Behavior And Children's Stress Biology, S.K. Jiaming Lin, Stacey N. Doan, John Milton

Scripps Senior Theses

Parenting behavior has been shown to have a wide range of effects, influencing children’s psychological and biological stress outcomes. Most research focuses on maternal parenting behaviors, with few studies observing the effects of paternal behaviors or the influence of both parents on their children. In this study, the relationship between maternal and paternal parenting behaviors was examined in its association to predict children’s cortisol levels. Cultural differences in parenting styles was also observed. American (N=86) and Chinese (N=97) families participated in the study, with parents reporting their behaviors. Children’s cortisol was collected during a stressor task and correlational analysis was …

Effects Of Multisensory Stop Signals On Sensitivity To Alcohol-Induced Disinhibition In Drinkers With Adhd, Alexandra R. D'Agostino

Theses and Dissertations--Psychology

Multisensory environments facilitate behavioral functioning in humans. The redundant signal effect (RSE) refers to the observation that individuals respond more quickly to stimuli when information is presented as multisensory, redundant stimuli rather than as a single stimulus presented to either modality alone. Our studies show that the disinhibiting effects of alcohol are attenuated when stop signals are multisensory versus unisensory. The present study expanded on this research to test the degree to which multisensory stop signals could also attenuate the disinhibiting effects of alcohol in those with attention-deficit hyperactivity disorder (ADHD), a clinical population characterized by poor impulse control. The …

Effects Of A Group-Deposit Prize Draw On The Step Counts Of Adults, Alex J. Mccurdy

University of the Pacific Theses and Dissertations

The World Health Organization (WHO, 2016) reports that 3.2 million deaths per year are attributable to physical inactivity, making it the fourth leading risk factor for global mortality. Physical inactivity is also a key risk factor for noncommunicable diseases such as cardiovascular disease, cancer, and diabetes (WHO, 2018). Globally, 1 in 4 adults is not active enough and, therefore, foregoes a myriad of health benefits associated with Physical Activity (PA; WHO, 2018). In the United States, only about 1 in 5 (21%) adults meet the 2008 Physical Activity Guidelines set by the Centers for Disease Control and Prevention (CDC, 2018). …

Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland

Theses and Dissertations--Psychology

The marriage of perspectives from behavioral economic theory and learning theory has the potential to advance an understanding of substance use and substance use disorder. Behavioral economic demand is a central concept to this interdisciplinary approach. Evaluating demand in the laboratory and clinic can improve previous research on the relative reinforcing effects of drugs by accounting for the multi-dimensional nature of reinforcement rather than viewing reinforcement as a unitary construct. Recent advances in the commodity purchase task methodology have further simplified the measurement of demand values in human participants. This dissertation project presents a programmatic series of studies designed to …

Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten

Theses and Dissertations--Psychology

Drug-specific reward and associated effects on neural signaling are often studied between subjects, where one group self-administers drug and a separate group self-administers a natural reinforcer. However, exposure to drugs of abuse can cause long-term neural adaptations that can affect how an organism responds to drug reward, natural reward, and their reward-associated stimuli. Thus, to isolate drug-specific effects it is important to use models that expose the same organism to all of the aforementioned. Multiple schedules provide a means of dissociating the rewarding effects of a drug from the rewarding effects of food within a single animal. Further, drug users …

Construction And Validation Of A Non-Medical Use Of Prescription Opioids Outcome Expectancies Scale Among College Students In China, Cheuk Chi Tam

Theses and Dissertations

Background:Non-medical use of prescription opioids (NMUPO) has become a clear threat to public health. Young adults (aged 18 to 25) have a high risk of NMUPO. My prior work on Chinese undergraduates indicates a high prevalence of lifetime NMUPO (49.2%). Health behavior theories propose that outcome expectancies are robust psychosocial determinants of substance use. Literature has identified the influence of outcome expectancies on alcohol and drug use. However, the role of outcome expectancies in NMUPO in China is unknown, and a scarcity of a valid measures for NMUPO outcome expectancies may be a barrier. Our previous research also found …

Examining Sleep And Family Functioning In Pediatric Craniopharyngioma Using Ecological Momentary Assessment, Nour Al Ghriwati

Theses and Dissertations

Craniopharyngiomas are among the most common brain tumors in children and are associated with greater rates of sleep problems compared to other pediatric cancers. However, research examining sleep among youth with craniopharyngioma has been limited by a reliance on retrospective reports or sleep studies. Families also play a crucial role in children’s adjustment following a pediatric cancer diagnosis, yet remarkably little is known about transactional associations between family functioning and sleep in pediatric cancer. This study examined cross-sectional and daily associations among family functioning, affect, and sleep difficulties for youth with pediatric craniopharyngioma using retrospective reports and ecological momentary assessment …

A Qualitative Study Exploring Motivation And Engagement Among Millennial Volunteers In Nonprofit Organizations, Joanne Quinones

Theses and Dissertations

This applied dissertation focused on capturing the lived experiences of Millennials and explore their motivation and engagement for volunteering in a nonprofit organization. This study illustrates the importance of civic and social engagement in our society. The Millennials have been labeled as “Genme or the me generation” (Twenge, Campbell, Hoffman, & Lance, 2010, p. 1117; Twenge, 2006, p. 1), as they have been criticized for focusing on their own self-interest. While millennials have been considered as being technologically savvy, since they grew up with the internet. The millennials, have a social interest in offering support to a cause versus an …

Values Vs. Self-Interest As Determinants Of Attitudes: Through A Construal Level Theory Lens, (Sometimes) Self-Interest Wins, Austin D. Eubanks

Graduate Theses and Dissertations

The present study (n = 335) attempted to conceptually replicate Hunt, Kim, Borgida, and Chaiken (2010) with a high-powered design to investigate whether values and self-interest differentially impact attitudes depending on psychological distance. Participants were assigned to complete a task that made self- or other-focused values more accessible, then indicated their attitudes about a student fee increase at a university to fund scholarships the participants would not be eligible to receive (thus going against their own financial self-interest for the well being of someone else). The memo describing the fee increase was manipulated such that the increase would be occurring …

Investigating Affective Pathways For The Influence Of Justification On Self-Control, Morgan Hill

Graduate Theses and Dissertations

People struggle with temptation in their everyday lives. Research often attributes failures in self-regulation to overwhelming and uncontrollable impulses. However, research also supports the idea that cognitive factors (e.g., justification) can license tempting behavior and allow individuals to behave in ways that run counter to their long-term goals. In addition, it is likely that affect plays a role in justification-based self-control failure. The current set of three studies investigated the role of affect in justification-based self-control failure. Study 1 tested the prediction that recall of past successes would result in increased positive affect. Study 2 assessed whether justification results in …

Measuring Novel Antecedents Of Mental Illness: The Questionnaire Of Unpredictability In Childhood, Laura M. Glynn, Hal S. Stern, Mariann A. Howland, Victoria B. Risbrough, Dewleen G. Baker, Caroline M. Nievergelt, Tallie Z. Baram, Elysia P. Davis

Psychology Faculty Articles and Research

Increasing evidence indicates that, in addition to poverty, maternal depression, and other well-established factors, unpredictability of maternal and environmental signals early in life influences trajectories of brain development, determining risk for subsequent mental illness. However, whereas most risk factors for later vulnerability to mental illness are readily measured using existing, clinically available tools, there are no similar measures for assessing early-life unpredictability. Here we validate the Questionnaire of Unpredictability in Childhood (QUIC) and examine its associations with mental health in the context of other indicators of childhood adversity (e.g., traumatic life events, socioeconomic status, and parenting quality). The QUIC was …

Treating Comorbid Ptsd And Bpd: A Dialectical Approach, Meredith Pescatello

Intuition: The BYU Undergraduate Journal of Psychology

According to the Biosocial Developmental Model for Borderline Personality Disorder (BPD), individuals with a biological vulnerability (i.e., heightened emotional sensitivity and impulsive tendencies), plus an invalidating environment may develop BPD (Crowell, Beauchaine, & Linehan, 2009). Individuals with BPD are especially difficult to treat, because of their “extreme emotional, behavioral, and cognitive dysregulation” (Crowell, Beauchaine, & Linehan, 2009). Though challenging to treat, BPD can be successfully treated using Dialectical Behavior Therapy (DBT) (Linehan, 1993; Linehan 2015). Similarly, Posttraumatic Stress Disorder (PTSD) is complex and often burnout inducing to treat, because of the intensity of the emotional content related to traumatic events …

Prompts To Increase Physical Activity At Points-Of-Choice Between Stairs And Escalators: What About Escalator Climbers?, John Belletierre, Ben Nguyen, Sandy Liles, Vincent Berardi, Marc A. Adams, Paddy Dempsey, Yael Benporat, Jacqueline Kerr, Andrea Z. Lacroix, Melbourne Hovell

Psychology Faculty Articles and Research

Since 1980, many studies have evaluated whether stair-use prompts increased physical activity by quantifying changes in stair use. To more completely evaluate changes in physical activity, this study addressed the often-overlooked assessment of climbing up escalators by evaluating the degree to which stair-use sign prompts increased active ascent—defined as stair use or escalator climbing. Over 5 months, at an airport stairs/escalator point of choice, we video-recorded passersby (N = 13,544) who ascended either stairs or escalators, on 10 days with signs and 10 days without signs. Ascenders using the stairs, standing on the escalator, and climbing the escalator were …

A Multimodal Assessment Of Disgust In Response To Traumatic Event Reminders Among Adolescents, Teah-Marie R. Bynion

Graduate Theses and Dissertations

The majority of youth will report traumatic event exposure by the time they reach adulthood. Research suggests exposure to such events is linked to myriad negative outcomes. Not all traumatic events are alike, however; evidence suggests that, compared to non-interpersonal events, interpersonal events in which another person intentionally perpetrates harm are linked to elevations in the likelihood of negative outcomes, including posttraumatic stress disorder (PTSD). One reason for this discrepancy is that interpersonal traumatic events may elicit greater levels of disgust. However, this is a very under-developed research base, no study has examined this question among youth. The current study …

Indirect & Displaced Aggression: The Role Of Comparison Based Traits And Cognitive Vulnerabilities, Niki M. Knight

Dissertations

The present study explored the relationships of contingent self-esteem, dispositional envy, and two cognitive vulnerabilities (i.e., anger rumination and fear of negative evaluation) to indirect aggression (IA) and displaced aggression (DA) in a college student sample (N = 346). Despite the theoretical relevance of these personality and cognitive factors to aggression, there is little empirical evidence linking them to the perpetration of IA and DA. Bivariate correlations and hierarchical multiple regression were used to test the utility of these constructs in accounting for unique variance in IA and DA and to assess the potential role of participant gender. Participants …

Identifying Clinical Distinctions Between Nonsuicidal Self-Injury And Eating Disorders In Adolescents, Natalie Marie Perkins

Masters Theses & Specialist Projects

Eating disorders and non-suicidal self-injury (NSSI) are pervasive behaviors that typically begin in early to mid-adolescence. They commonly co-occur, resulting in increasingly negative psychological and physical outcomes than either behavior alone. Emotion reactivity and family functioning have been studied in relation to both eating disorders and NSSI. Both constructs have demonstrated strong relationships to these behaviors, but emotion reactivity appears to be more strongly associated with NSSI, while family functioning appears to be more strongly related to eating disorders. The current study sought to determine whether emotion reactivity and family functioning could differentiate between adolescents with only an eating disorder, …

Psychological Well-Being And Restorative Biological Processes: Hdl-C In Older English Adults, Jackie Soo, Laura D. Kubzansky, Ying Chen, Emily S. Zevon, Julia K. Boehm

Psychology Faculty Articles and Research

Rationale

Psychological well-being is associated with better cardiovascular health, but the underlying mechanisms are unclear.

Objective

This study investigates one possible mechanism by examining psychological well-being's prospective association with lipid levels, focusing on high-density lipoprotein cholesterol (HDL-C).

Methods

Participants were 4757 healthy men and women ages ≥50 from the English Longitudinal Study of Ageing with clinical data from three times, three to five years apart. Psychological well-being was assessed at baseline using the Control, Autonomy, Satisfaction, and Pleasure scale; HDL-C, triglycerides, and total cholesterol were assayed from blood samples. Descriptive statistics and linear mixed models were used to examine associations …

Treating Adhd With Suggestion: Neurofeedback And Placebo Therapeutics, Robert T. Thibault, Samuel Vassière, Jay A. Olson, Amir Raz

Psychology Faculty Articles and Research

Objective: We propose that clinicians can use suggestion to help treat conditions such as ADHD. Methods: We use EEG neurofeedback as a case study, alongside evidence from a recent pilot experiment utilizing a sham MRI scanner to highlight the therapeutic potential of suggestion-based treatments. Results: The medical literature demonstrates that many practitioners already prescribe treatments that hardly outperform placebo comparators. Moreover, the sham MRI experiment showed that, even with full disclosure of the procedure, suggestion alone can reduce the symptomatology of ADHD. Conclusion: Non-deceptive suggestion-based treatments, especially those drawing on accessories from neuroscience, may offer a safe complement and potential …