Psychiatry and Psychology Commons^™

Explaining The Longitudinal Association Between Puberty And Depression: Sex Differences In The Mediating Effects Of Peer Stress, Colleen S. Conley, Karen D. Rudolph, Fred B. Bryant

Psychology: Faculty Publications and Other Works

This research investigated whether exposure to peer stress serves as one pathway through which pubertal development contributes to depression over time, differentially for girls and boys. Youth (N = 149; 9.6–14.8 years) and their caregivers provided information at two waves, 1 year apart, on puberty (Wave 1), peer stress (occurring between Waves 1 and 2), and depression (Waves 1 and 2). Structural equation modeling analyses examined sex differences in the extent to which peer stress mediated the impact of pubertal status and timing on subsequent depression (i.e., tests of moderated mediation). Significant sex-moderated mediation was found for both pubertal status …

Perceived Discrimination And Depression As It Relates To Nativity Status Of Students From Immigrant Backgrounds, Melissa Huey

Dissertations and Theses

"Research has found that foreign born immigrants' have better mental and physical health, as well as higher levels of academic achievement, than native born individuals from immigrant families (Vega, et. al., 2004). There is some evidence that perceived discrimination could be a possible explanation for these nativity differences (Juang & Cookston, 2009). The current study tested the hypothesis that native born individuals from immigrant backgrounds will have higher levels of depression than their foreign born counterparts and that native born respondents will report higher levels of perceived discrimination than foreign born. The study also tested whether perceived discrimination mediates the …

Conflicts Of Interest In Clinical Practice Guidelines, Lisa Cosgrove, Allen F. Shaughnessy

Counseling, School Psychology & Sport Faculty Publication Series

Clinical practice guidelines are used increasingly across medical specialties and settings, making evaluation of their utility and validity a critical public health issue. In this paper, we describe some of the challenges that specialty organizations face as they try to ensure that their guidelines are trustworthy and useful. We examine the practice guidelines for Major Depressive Disorder recently published by the American Psychiatric Association (APA), identify five sources of potential bias that may affect the guideline development process and offer suggestions based on our review. For example, even for mild depression, this guideline privileges pharmacotherapy over other interventions, despite questions …

Does Fish Oil Supplementation (Omega-3 Pufa) Cause Mood Improvement In Adults With Depression, Lauren Cabana

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic review is to determine whether or not “Does fish oil supplementation (omega-3 PUFA) cause mood improvement in adults with depression?”

The Role Of Gender In Single Vs Married Individuals With Bipolar Disorder., Daniel Z Lieberman, Suena H Massey, Frederick K Goodwin

Psychiatry and Behavioral Sciences Faculty Publications

BACKGROUND: Despite the importance of marriage as a source of social support, it has been largely neglected in studies of bipolar disorder; and differential effects on men and women have not been explored.

METHODS: Data on episodes of depression, mania, and mixed states were collected for the previous 2 years from a sample of 282 bipolar individuals using the National Institute of Mental Health Life Chart Methodology.

RESULTS: Effects unique to women included the following: Bipolar women were significantly more likely to be married. Married women had fewer episodes of depression during the past 2 years than never-married women, and …

Major Depression : Diagnosis And Intervention, Lindsay Linck

Graduate Research Papers

This paper will be an analysis of the psychological disorder of major depression. First, the classification of this disorder using the DSM-IV-TR will be reviewed. The areas of etiology, differential diagnosis, and treatment will then be considered. Following, a theory-specific approach to the disease including theoretical framework, diagnosis and treatment, and outcomes of using this approach, will be examined. Finally a personal reflection on the subject of major depression, and lessons learned from this project, will be discussed.

Should Schizoaffective Disorder Be Dropped From Dsm V, Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Depressive Symptoms And Marital Satisfaction In The Context Of Chronic Disease: A Longitudinal Dyadic Analysis, Rachel Pruchno, Maureen Wilson-Genderson, Francine P Cartwright

Rowan-Virtua School of Osteopathic Medicine Departmental Research

These analyses examined the longitudinal relationships between depressive symptoms and marital satisfaction over a 2-year period as experienced by 315 patients with end-stage renal disease and their spouses. Using multilevel modeling, the authors examined both individual and cross-partner effects of depressive symptoms and marital satisfaction on patients and spouses, testing bidirectional causality. Results indicate that mean and time-varying depressive symptoms of both patients and spouses were associated with their own marital satisfaction. Although mean marital satisfaction was associated with own depressive symptoms for both patients and spouses, time-varying marital satisfaction did not affect depressive symptoms for either patients or spouses. …

The Role Of The Peer Group In Adolescence: Effects On Internalizing And Externalizing Symptoms, Glen J. Veed

Department of Psychology: Dissertations, Theses, and Student Research

An adolescent’s peer group has been theorized to influence the development of psychopathology. However, little research has examined the adolescent peer group using information obtained directly from peers in a longitudinal framework. Research has also been limited on peer group influence on the development of internalizing disorders. The study used Social Network Analysis to examine self-reported anxiety, depression, aggression, and delinquency in the fall and spring of one school year for students in a rural high school. In addition to examining the effect of the peer group on individual reports of psychopathology, the strength of this relation was compared to …

Selecting Antidepressant Drugs For Management Of Depression In Primary Care (Part 2), Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Selecting Antidepressant Drugs For Management Of Depression In Primary Care (Part 1), Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Treatment Resistant Depression, Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Resting State Default-Mode Network Connectivity In Early Depression Using A Seed Region-Of-Interest Analysis: Decreased Connectivity With Caudate Nucleus, Robyn Bluhm, Peter Williamson, Ruth Lanius, Jean Théberge, Maria Densmore, Robert Bartha, Richard Neufeld, Elizabeth Osuch

Philosophy Faculty Publications

Aim: Reports on resting brain activity in healthy controls have described a default-mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting-state DMN in relatively early depression before years of medication treatment. The objective of the present study was, therefore, to investigate the DMN in patients seeking help from specialized mental health services for the first time for symptoms of depression.

Methods: Fourteen depressed subjects and 15 matched controls were scanned using 4-T functional magnetic resonance imaging while resting with eyes closed. All but one subject was …

Small Individual Loans And Mental Health: A Randomized Controlled Trial Among South African Adults, Lia C. H. Fernald, Rita Hamad, Dean Karlan, Emily J. Ozer, Jonathan Zinman

Dartmouth Scholarship

Background: In the developing world, access to small, individual loans has been variously hailed as a poverty-alleviation tool – in the context of "microcredit" – but has also been criticized as "usury" and harmful to vulnerable borrowers. Prior studies have assessed effects of access to credit on traditional economic outcomes for poor borrowers, but effects on mental health have been largely ignored.

Methods: Applicants who had previously been rejected (n = 257) for a loan (200% annual percentage rate – APR) from a lender in South Africa were randomly assigned to a "second-look" that encouraged loan officers to approve their …

Mood Symptoms As Comorbidity In Schizophrenia, Amresh Srivastava

Psychiatry Presentations

No abstract provided.

Predictors Of Depressive And Anxiety Symptoms Among African American Hiv-Positive Women, Nina Katherine Sublette

Theses and Dissertations (ETD)

This descriptive correlation study had four purposes: describe depressive and anxiety symptom levels in pregnant and non-pregnant African American (AA) HIV-positive women, examine the association between underlying vulnerabilities and depressive symptoms in HIV-positive AA women, determine the association between underlying vulnerabilities and anxiety symptoms in AA HIV-positive women, and determine the predictors of depressive and anxiety symptoms among African American HIV-positive women. A convenience sample of 80 African American HIV-positive women was recruited from university-based obstetrics/-gynecology and infectious disease practices in a large metropolitan city in the Mid-South. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale …

Depression In Parkinson's Disease: Health Risks, Etiology, And Treatment Options, Pasquale G. Frisina, Joan C. Borod, Nancy S. Foldi, Harriet R. Tenenbaum

Publications and Research

Depression is found in about 30%-40% of all patients with Parkinson's disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function), etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy). The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin) …

Resting And Reactive Frontal Brain Electrical Activity (Eeg) Among A Non-Clinical Sample Of Socially Anxious Adults: Does Concurrent Depressive Mood Matter?, Elliott A. Beaton, Louis A. Schmidt, A R. Ashbaugh, D L. Santesso, M M. Antony, R E. Mccabe

Psychology Faculty Publications

A number of studies have noted that the pattern of resting frontal brain electrical activity (EEG) is related to individual differences in affective style in healthy infants, children, and adults and some clinical populations when symptoms are reduced or in remission. We measured self-reported trait shyness and sociability, concurrent depressive mood, and frontal brain electrical activity (EEG) at rest and in anticipation of a speech task in a non-clinical sample of healthy young adults selected for high and low social anxiety. Although the patterns of resting and reactive frontal EEG asymmetry did not distinguish among individual differences in social anxiety, …

A Review Of The Tripartite Model For Understanding The Link Between Anxiety And Depression In Youth, Emily R. Anderson, Debra A. Hope

Department of Psychology: Faculty Publications

Although research from numerous investigations indicates that there is substantial overlap in anxiety and depressive symptoms and comorbid diagnoses in youth, these constructs can be adequately differentiated. Clark and Watson [Clark, L. A. & Watson, D., (1991). Tripartite model of anxiety and depression: Psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100: 316-336] proposed a tripartite model to account for the symptom overlap and diagnostic comorbidity between anxiety and depression. This tripartite model posits that anxiety and depression share a common component of negative affect, but can be differentiated by low positive affect associated with depression and high …

Peer Victimization, Depression, And Suicidality In Adolescents, Anat Brunstein Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

The association between specific types of peer victimization with depression, suicidal ideation, and suicide attempts among adolescents was examined. A self-report survey was completed by 2,342 high-school students. Regression analyses indicated that frequent exposure to all types of peer victimization was related to high risk of depression, ideation, and attempts compared to students not victimized. Infrequent victimization was also related to increased risk, particularly among females. The more types of victimization the higher the risk for depression and suicidality among both genders. Specific types of peer victimization are a potential risk factor for adolescent depression and suicidality. It is important …

Negative Mood Regulation Mediates The Relationship Between Distraction And Engagement In Pleasurable Activities Among College Smokers, Lee M. Cohen, Dennis E. Mcchargue, Holly E. R. Morrell

Department of Psychology: Faculty Publications

Smoking for negative mood alleviation is a strong predictor of early smoking and early dependence among undergraduates. Little is known about whether adaptive cognitive coping processes (e.g., distraction) may help decrease the likelihood of student smoking for negative mood regulation. The present study tested the hypothesis that distraction would predict (a) greater engagement in adaptive pleasant pastimes and (b) lower rates of smoking behavior among undergraduates (n = 162, 41.9% female). We further assessed whether negative mood regulation expectations would explain both relationships. Results indicated that negative mood regulation fully mediated the relationship between distraction and engagement in pleasurable …

Fluoxetine, Smoking, And History Of Major Depression: A Randomized Controlled Trial, Bonnie Spring, Neal Doran, Sherry Pagoto, Dennis E. Mcchargue, Jessica Werth Cook, Katherine Bailey, John Crayton, Donald Hedecker

Department of Psychology: Faculty Publications

The study was a randomized placebo-controlled trial testing whether fluoxetine selectively enhances cessation for smokers with a history of depression. Euthymic smokers with (H+, n = 109) or without (H-, n = 138) a history of major depression received 60 mg fluoxetine or placebo plus group behavioral quit-smoking treatment for 12 weeks. Fluoxetine initially enhanced cessation for H+ smokers (p = .02) but subsequently impaired cessation regardless of depressive history. Six months after quit date, fluoxetine-treated participants were 3.3 times more likely to be smoking (p = .02). Further research is warranted to determine why high-dose fluoxetine produces …

Bullying, Depression, And Suicidality In Adolescents, Anat Brunstein-Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

Objective: To assess the association between bullying behavior and depression, suicidal ideation, and suicide attempts among adolescents. Method: A self-report survey was completed by 9th- through 12th-grade students (n = 2342) in six New York State high schools from 2002 through 2004. Regression analyses were conducted to examine the association between being victimized and bullying others with depression, ideation, and attempts. Results: Approximately 9% of the sample reported being victimized frequently, and 13% reported bullying others frequently. Frequent exposure to victimization or bullying others was related to high risks of depression, ideation, and suicide attempts compared with adolescents not involved …

Peer Victimization, Depression, And Suicidality In Adolescents, Anat Brunstein Klomek, Frank Marrocco, Marjorie Kleinman, Irvin Sam Schonfeld, Madelyn S. Gould

Publications and Research

Objective: To assess the association between bullying behavior and depression, suicidal ideation, and suicide attempts among adolescents. Method: A self-report survey was completed by 9th- through 12th-grade students (n = 2342) in six New York State high schools from 2002 through 2004. Regression analyses were conducted to examine the association between being victimized and bullying others with depression, ideation, and attempts. Results: Approximately 9% of the sample reported being victimized frequently, and 13% reported bullyingothers frequently. Frequent exposure to victimization or bullying others was related to high risks of depression, ideation, and suicide attempts compared …

Relation Between Anger And Depression And Predictors Of Anger Among Residents Of Assisted Living Facilities, Masami Tokumo

Seton Hall University Dissertations and Theses (ETDs)

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The Role Of Spiritual Well-Being In Moderating Frail Elders' Affective Response To Functional Difficulty, Marie P. Dennis, Laura N. Gitlin, Laraine Winter, Yeon K. Chee

Center for Applied Research on Aging and Health Research Papers

Anxiety and depression have been well documented as affective consequences of functional impairment. Little research, however, has examined factors that moderate these associations. The present cross-sectional study examined the role of spiritual well-being in buffering the impact of functional difficulty on the anxiety and depressive symptoms of 319 functionally vulnerable community-dwelling elders, aged 70 or older, participating in a 6-month randomized controlled trial designed to enhance function. As demonstrated in recent research on spirituality and health, we expected that spiritual well-being would moderate the association between functional difficulty and anxiety as well as the relationship between functional difficulty and depression. …

Novelty Reward As A Measure Of Anhedonia, Rick A. Bevins, Joyce Besheer

Department of Psychology: Faculty Publications

A decrease in sensitivity to pleasurable stimuli, anhedonia, is a major symptom of depression in humans. Several animal models have been developed to simulate this symptom (e.g. drug withdrawal, learned helplessness) using reward-sensitive procedures such as intracranial self-stimulation and progressive ratio responding as a measure of reward function. Recently, we introduced the use of another procedure, novel-object place conditioning in rats, to measure reward function in an associative learning situation. Withdrawal from chronic nicotine blocked a place preference conditioned by access to novel objects. This blockade was not due to impairment of object interaction, general activity, novelty detection, environmental familiarization, …

Attachment And Depression Differentially Influence Nicotine Dependence Among Male And Female Undergraduates: A Preliminary Study, Dennis E. Mcchargue, Lee M. Cohen, Jessica W. Cook

Department of Psychology: Faculty Publications

The authors surveyed a convenience sample of 208 undergraduate students who reported that they smoked cigarettes. The primary hypothesis they tested was whether gender predicted nicotine dependence. They further tested whether depression and attachment would mediate or moderate this relationship. Hierarchical regression analyses with social desirability and smoking stage of change entered as covariates indicated that women exhibited greater nicotine dependence than men did (p < .01). Lower attachment scores fully mediated this relationship, whereas elevated depression scores moderated the relationship. These findings suggest that depression and the inability to bond with peers may promote nicotine dependence among young female students.

Serotonin Transporter And Gaba(A) Alpha 6 Receptor Variants Are Associated With Neuroticism, Srijan Sen, Sandra Villafuerte, Randolph Nesse, Scott F. Stoltenberg, Jeffrey Hopcian, Lillian Gleiberman, Alan Weder, Margit Burmeister, University Of Michigan - Ann Arbor

Department of Psychology: Faculty Publications

Background: A tendency to experience negative affect, as measured by the neuroticism component of the Neuroticism, Extraversion, and Openness Personality Inventory (NEO-PI), is a trait marker for major depression. Epidemiologic studies indicate a strong genetic component, but to date few specific genetic variants have been definitively implicated. A serotonin transporter promoter polymorphism (5-HTTLPR) has been extensively studied in neuroticism and several psychiatric disorders, with inconclusive results. A GABA(A) receptor α6 subunit variant (Pro385Ser) has been associated with alcohol-related traits but has not been studied in neuroticism or depression.
Methods: A total of 384 subjects who completed the NEO-PI were genotyped …

How Individuals Understand Depression: Attributions, Stigma, And Treatment Recommendations, Erin A. Pladsen

Psychology Theses & Dissertations

This study examined participants' beliefs/attributions about depression, their help seeking recommendations for depressed individuals, and the stigma associated with depression. Participants were asked to read a vignette that described a target person who is suffering from depression, and they were asked to complete various questionnaires based upon the vignette. Overall, the results indicated that individuals did not possess negative attitudes toward mental illness, that individuals more strongly recommended professional mental health assistance, and that individuals did not tend to stigmatize depressed individuals. Results did indicate that the label of depression and the gender of the target person affected provider type …