Psychiatry and Psychology Commons^™

Improving Patient Outcomes In Substance Use Disorder Through Behavioral Therapy In Depression Development And Impacts Of Social Determinants Of Health During And After Substance Use Treatment, Jerry Ryan Armstrong, Chyanne Napp

Doctoral Projects

Substance Use Disorder (SUD) is a growing problem in the United States (U.S.) and worldwide and relapse is a common occurrence among those facing SUD. Limited scholarly research has been published addressing evidence-based treatment improvement strategies. This study focused on improving SUD treatment through the incorporation of depression tracking from admission to and discharge from inpatient treatment, as well as the incorporation of social determinants of health education during treatment, with an evaluation of relapse rates 30-days after inpatient treatment discharge. Results indicated a significant improvement in depression scores from admission to discharge. Results also revealed improved knowledge regarding social …

The Feasibility And Utility Of Harnessing Digital Health To Understand Clinical Trajectories In Medication Treatment For Opioid Use Disorder: D-Tect Study Design And Methodological Considerations, Lisa A. Marsch, Ching-Hua Chen, Sara R. Adams, Asma Asyyed, Monique B. Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C. Jacobson, Heather K. Jones, David Kotz, Chantal A. Lambert-Harris, Zhiguo Li, Bethany Mcleman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Cynthia I. Campbell

Dartmouth Scholarship

Introduction: Across the U.S., the prevalence of opioid use disorder (OUD) and the rates of opioid overdoses have risen precipitously in recent years. Several effective medications for OUD (MOUD) exist and have been shown to be life-saving. A large volume of research has identified a confluence of factors that predict attrition and continued substance use during substance use disorder treatment. However, much of this literature has examined a small set of potential moderators or mediators of outcomes in MOUD treatment and may lead to over-simplified accounts of treatment non-adherence. Digital health methodologies offer great promise for capturing intensive, longitudinal ecologically-valid …

Nonjudgmental Acceptance: Associations With Substance-Related Cue Reactivity In Adults With Substance Use Disorders And Posttraumatic Stress, Anka A Vujanovic, Heather E Webber, Margaret C Wardle, Charles E Green, Scott D Lane, Joy M Schmitz

Faculty, Staff and Student Publications

The present investigation examined the predictive utility of nonjudgmental acceptance, a facet of mindfulness defined as the ability to remain aware and nonevaluative about internal experience, in terms of substance-related cue reactivity among adults with substance use disorders (SUD) and posttraumatic stress (PTS) symptomatology. We hypothesized that higher nonjudgmental acceptance, indexed via self-report, would predict higher levels of self-reported control over oneself and safety 'in the moment', broadly, and lower levels of substance-related craving in response to substance script cues. Effects were expected after subtracting reactivity to neutral script cues from each outcome rating. PTS severity was included as a …

Impact Of A Reduced Nicotine Standard On Young Adult Appeal For Menthol And Non-Menthol Cigarettes, Amy M. Cohn, Rachel Cassidy, Rachel Denlinger-Apte, Eric Donny, Andrea C. Villanti, Dorothy Hatsukami, Delaney Dunn, Riley Wyatt, Taylor Niznik, Tamar Cohen-Davidyan, Michael Smith, Sarah J. Ehlke

Psychology Faculty Publications

Introduction The Food and Drug Administration (FDA) announced its intention to reduce the nicotine content in cigarettes as a strategy to promote cessation and reduce smoking-related harm. A low nicotine product standard will apply to all cigarettes on the market, including menthol cigarettes. In December 2021, the FDA approved a modified risk tobacco product application for menthol and non-menthol flavoured very low nicotine cigarettes (VLNC) from the 22nd Century Group. Notably, experimentation with menthol cigarettes is linked to smoking progression, as well as greater nicotine dependence relative to non-menthol cigarette use. If menthol VLNCs are perceived as more appealing than …

Advancing Behavioral Health Literacy, James Scollione

Journal of Social, Behavioral, and Health Sciences

Accessing, comprehending, and using information to make informed decisions and improve one’s overall health or well-being are the foci of health literacy. The concept of behavioral health was introduced in the early 1980s and, since then, it has influenced new ideas (e.g., behavioral health literacy and integrated behavioral health care) and gained research and public attention. My aim is to provide an overview of definitions (i.e., health literacy, mental health literacy, and behavioral health literacy) and their connection to each other. I propose an expanded and honed definition of behavioral health literacy to enhance the behavioral health literacy and well-being …

Knowing What We Know: Leveraging Community Knowledge Through Automated Text-Mining, Justin Gardner, Jonathan Tory Toole, Hemant Kalia, Garry Spink Jr., Gordon Broderick

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.

Dialectical Behavior Therapy For Dual Diagnosis: Treating Adolescent Substance Use Disorder And Co-Occurring Mood Disorders, Melody R. Gately

Senior Honors Projects

No abstract provided.

Naloxone/Buprenorphine, Methadone, Naltrexone And Their Role In Medication Assisted Treatment, Robert Barrett

Capstone Showcase

Abstract

Opioid use disorder (OUD) is an increasingly common diagnosis that has drastically increased in the last 5 years. Though multiple treatment modalities exist for treating OUD (naltrexone, buprenorphine, methadone), few studies have compared treatment outcomes in adults on long term therapy. This is an important topic to understand as providers as we will undoubtedly come into contact with patients either actively abusing opioid antagonists or in recovery from opioid abuse. Since the introduction of Oxycontin and subsequent over prescription of opioid analgesics, opioid overdoses have increased by over twelve-fold. Once providers began to realize a widespread pattern of abuse, …

Why Can't Homeless Addicts Get Help Too, Rachael D. Causland

English Department: Research for Change - Wicked Problems in Our World

Homeless people today struggle more with addiction than people who have stability in their life. Whether it’s due to financial issues, or not having a support system, homeless people struggle to get the help they need for both their addiction and their homelessness. A high number of homeless people report to have started an addiction since being homeless, and they do so to stay alive, in turn people are continuing to stay homeless and many of these people are dying of overdoses or just staying stuck in the situation they are forced to deal with alone. There are some states …

The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio

Honors Theses and Capstones

Social media use has increased substantially in recent years, and for the college-aged population, social media is often the leading method of communication. Research indicates this reliance on digital connection could have a negative impact on the health of young adults (Bagroy et al., 2017). The college years are a time of personal growth and defining actions, yet can also be burdened by mental health issues related to stress, anxiety, and depression (Hunt & Eisenberg, 2010). Acknowledging these trends, the current study explores how college students’ specific frequency and intentionality while interacting on social media relates to their psychological well-being. …

Psychometric Properties Of Bergen Social Media Addiction Scale (Bsmas) In Malay Version, Kee Hui Romi Tiong

Student Works (2020-2029)

Background The percentage of internet users in Malaysia has recorded continuous increment annually, in which it increased from 76.9% in 2016 to 87.4% of users in 2018. The prevalent use of all sorts of social media platform and the convenient access to the internet regardless of time and place has massively enhance the potential of social media addiction. After many years of research, the researchers have yet to reach the consensus in identifying criteria to diagnose problematic attachment to social media. The aim of the study was to validate the Malay version of Bergen Social Media Addiction Scale (BSMAS), by …

Non-Pharmacological Interventions For Alcohol, Marijuana, And Opioid Use During Pregnancy: A Systematic Review, Hannah Safranek, Madeline Frausto, Amy King, Stoneking Madison

Williams Honors College, Honors Research Projects

The purpose of this review is to analyze evidence on prevalence of opioid, alcohol and marijuana use during pregnancy and answer the PICOT question: In pregnant women addicted to or using marijuana, opioids, and alcohol, how do non-pharmacological interventions, compared to standard care of pharmacological interventions alone, affect health outcomes in mothers and neonates between birth to hospital discharge? Diagnosis of substance use disorder is increasing and with it comes increased risk of complications to mother and neonate including neonatal abstinence syndrome (NAS), fetal alcohol syndrome (FAS) and other negative neonatal and maternal outcomes. Evidence was identified on the online …

Choice Of God/Higher Power, Perceptions Of God/Higher Power, Religious Beliefs And Behaviors, And Social Support As Predictors Of Length Of Sobriety, Satisfaction With Life, And Quality Of Life Among People Recovering From Alcohol Addictions In Three Midwestern States, Carlton Martin

Dissertations

Problem

An estimated 12.7% of the US population meet the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV) (American Psychiatric Association, 1994) criteria for Alcohol Use Disorder (AUD). The annual cost to the society, including emergency room visits, lost days at work, and accidents on the road is in the billions. The impact of this disorder on the family, the community, and the individual is immeasurable. A growing body of literature supports an association between religious and spiritual beliefs and behaviors and recovery from alcohol addiction. This project is an investigation of this association. The goal is to offer some …

Internet Addiction And The Relationship To Self And Interpersonal Functioning Within The Alternative Model For Personality Disorders (Ampd): Implications For Psychosocial Development, Lori L. Woehler

Antioch University Dissertations & Theses

Internet addictive use inclusive of inextricably interconnected mobile devices, applications, and social media predicts diminished Self and Interpersonal functioning. Internet addiction research is burdened by conflicting theoretical views, lack of standardized definitions and criteria, and the use of assessment measures adapted from those used for substance use disorders. Alternative and dimensional diagnostic models for internet addiction through a psychosocial developmental lens might further understanding of Internet addiction and reduce challenges which impact the ability to advance research and achieve clinically useful, culturally informed, and evidence-based practices for the assessment and treatment of Internet addiction.

A Comparison Of Opioid Abuse Screening Tools Of Detection Of High Risk Patients In The Inpatient Setting, Grace Gu Md, Albert Cheng Md, Darren Rahaman Md, Shyh-Jeun Wang Md, Maureen Strohm Md, Napatkamon Ayutyanont

Family Medicine

• The United States is currently experiencing an opioid epidemic, which claims 115 lives daily by overdose.
• Tools for identifying patients at increased risk for abuse include: Screener and Opioid Assessment for Patients with Pain (SOAPP-R) and Opioid Risk Tool (ORT).
• However, data is lacking for the comparison of the two most commonly used opioid screen tools (SOAPP-R and ORT).
• We are comparing the effectiveness of these screening tools for patients being discharged from the hospital who have no "red flags" for abuse.

Approach Bias For Erotic Stimuli In Heterosexual Male College Students Who Use Pornography, Shane Kraus, Skyler Sklenarik, Marc N. Potenza, Mateusz Gola, Ariel Kor, Robert S. Astur

Psychology Faculty Research

Background and Aims: Addicted individuals often demonstrate relatively automatic action tendencies in response to addiction-related stimuli, whereby they approach rather than avoid addictive stimuli. This study assessed whether an approach bias for erotic stimuli exists among heterosexual college-aged males who report using pornography. Methods: We tested 72 male undergraduate students using an approach–avoidance task employing erotic stimuli, during which participants were instructed to push or pull a joystick in response to image orientation. To simulate approach and avoidance movements, pulling the joystick enlarged the image and pushing shrunk the image. Frequency and severity of pornography use was assessed using a …

Adgrl3 (Lphn3) Variants Predict Substance Use Disorder, Mauricio Arcos-Burgos, Jorge I. Vélez, Ariel F. Martinez, Marta Ribasés, Josep A. Ramos-Quiroga, Cristina Sánchez-Mora, Vanesa Richarte, Carlos Roncero, Bru Cormand, Noelia Fernández-Castillo, Miguel Casas, Francisco Lopera, David A. Pineda, Juan D. Palacio, Johan E. Acosta-López, Martha L. Cervantes-Henriquez, Manuel G. Sánchez-Rojas, Pedro J. Puentes-Rozo, Brooke S. G. Molina, Mta Cooperative Group, Margaret T. Boden, Deeann Wallis, Brett Lidbury, Saul Newman, Simon Easteal, James Swanson, Hardip Patel, Nora Volkow, Maria T. Acosta, Francisco X. Castellanos, Jose De Leon

Psychiatry Faculty Publications

Genetic factors are strongly implicated in the susceptibility to develop externalizing syndromes such as attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, conduct disorder, and substance use disorder (SUD). Variants in the ADGRL3 (LPHN3) gene predispose to ADHD and predict ADHD severity, disruptive behaviors comorbidity, long-term outcome, and response to treatment. In this study, we investigated whether variants within ADGRL3 are associated with SUD, a disorder that is frequently co-morbid with ADHD. Using family-based, case-control, and longitudinal samples from disparate regions of the world (n = 2698), recruited either for clinical, genetic epidemiological or pharmacogenomic studies of ADHD, we …

An Investigation Of Personality Traits As Predictors For Mobile Phone Dependency, Elijah Phillips

Senior Honors Projects, 2010-2019

This study sought to determine if certain personality traits are correlates of mobile phone dependency, motivations for purchasing a mobile phone, and reasons for commonly using a cell phone. The impact of mobile phones on human day-to-day living and the interplay between cellular devices and human behavior have been topics of ongoing research. Through these investigatory efforts, numerous potential harms of mobile phone overuse and abuse have recently become increasingly apparent, but very little research has generated conclusive results about the interaction between human persona and mobile dependency. This was a cross-sectional study of a quasi-randomized sample of undergraduate students …

Reanalyzing The Activity Anorexia Protocol Using An Addiction Theory, Rolando Alfredo Botello

Theses and Dissertations

One researched and developed phenomenon is activity anorexia (AA) in rats and its resemblance to the human pathology anorexia nervosa (AN). Researchers have long relied on this comparative model for AN as AA. This study aims to reanalyze the overt physiological phenomena of AA to test an addictive theory against the prevalent AA theory. Equal numbers of subjects could eat or run during a one hour feeding period and all activity was monitored per 30 minutes. Results showed that daily running correlated with an increase in food consumption with no effect of food suppression. The only factor that regressed to …

Anticipatory Motivation For Drinking Alcohol: An In-Vivo Study, Bryan Benitez

USF Tampa Graduate Theses and Dissertations

Numerous studies from various research groups have already shown the usefulness of alcohol expectancies as predictors of long-term future alcohol consumption. The present study extends this line of research by directly testing whether alcohol expectancies measured in the moment using free association are useful as predictors of alcohol consumption in the next few hours. An ecological momentary assessment (EMA) procedure was used to examine how alcohol expectancies might fluctuate during days in which many people expect to drink (e.g. Fridays, Saturdays) and how these fluctuations in alcohol expectancies might predict future drinking and/or co-vary with important contextual variables during that …

The Effect Of Early Life Photoperiod Manipulation On Cocaine-Induced Behavioral Sensitization In Male And Female Japanese Quail, Shannon Elizabeth Eaton

Theses and Dissertations--Psychology

Estrogens seem to play a role in the locomotor activating effects of cocaine. Japanese quail provide a good model for hormonal manipulation as alterations of their photoperiod controls hormone levels. The current study aims to examine the role of early life photoperiod manipulation in cocaine-induced behavioral sensitization in quail. It was expected that if quail were raised on a short photoperiod, they would have a reduction in gonadal hormones and this reduction in hormones would affect the acquisition of cocaine-induced behavioral sensitization. Quail were raised on an 8L:16D or a 16L:8D light cycle. Following 2 days of habituation, quail were …

A Randomized Placebo-Controlled Trial Of N-Acetylcysteine For Cannabis Use Disorder In Adults, Kevin M. Gray, Susan C. Sonne, Erin A. Mcclure, Udi E. Ghitza, Abigail G. Matthews, Aimee L. Mcrae-Clark, Kathleen M. Carroll, Jennifer S. Potter, Katharina Wiest, Larissa J. Mooney, Albert Hasson, Sharon L. Walsh, Michelle R. Lofwall, Shanna Babalonis, Robert W. Lindblad, Steven Sparenborg, Aimee Wahle, Jacqueline S. King, Nathaniel L. Baker, Rachel L. Tomko, Louise F. Haynes, Ryan G. Vandrey, Frances R. Levin

Behavioral Science Faculty Publications

Background—Cannabis use disorder (CUD) is a prevalent and impairing condition, and established psychosocial treatments convey limited efficacy. In light of recent findings supporting the efficacy of N-acetylcysteine (NAC) for CUD in adolescents, the objective of this trial was to evaluate its efficacy in adults.

Methods—In a 12-week double-blind randomized placebo-controlled trial, treatment-seeking adults ages 18–50 with CUD (N=302), enrolled across six National Drug Abuse Treatment Clinical Trials Network-affiliated clinical sites, were randomized in a 1:1 ratio to a 12-week course of NAC 1200 mg (n=153) or placebo (n=149) twice daily. All …

Neurophysiological Capacity In A Working Memory Task Differentiates Dependent From Nondependent Heavy Drinkers And Controls, Michael J. Wesley, Joshua A. Lile, Mark T. Fillmore, Linda J. Porrino

Behavioral Science Faculty Publications

Background—Determining the brain-behavior profiles that differentiate heavy drinkers who are and are not alcohol dependent will inform treatment efforts. Working memory is linked to substance use disorders and can serve as a representation of the demand placed on the neurophysiology associated with cognitive control.

Methods—Behavior and brain activity (via fMRI) were recorded during an N-Back working memory task in controls (CTRL), nondependent heavy drinkers (A-ND) and dependent heavy drinkers (A-D). Typical and novel step-wise analyses examined profiles of working memory load and increasing task demand, respectively.

Results—Performance was significantly decreased in A-D during high working memory load …

Understanding Alcoholics’ “Difficulty In Life”: An Empirical Comparison Of Alcoholics And Nonalcoholics, Keiko Ito

Asian/Pacific Island Nursing Journal

The Japanese success rate for alcoholism treatment is approximately 30%, indicating high relapse rates. Although “difficulty in life” is thought to contribute to alcoholics’ relapse, the characteristics of the phenomenon are unknown. This study examined the factors contributing to alcoholics’ difficulty in life. Alcoholic self-help group members, who indicated the extent of their difficulty in life and described the factors that contributed to this difficulty, completed a self-administered questionnaire. Participants’ hypersensitivity/grandiosity traits were also examined. A control group of nonalcoholic men also completed the questionnaire. Simple tabulation, descriptive statistics, Mann-Whitney U tests, and multivariate analyses were used to compare data …

The Impact Of Stress On Steroid Hormones And Cue Reactivity In Smokers And Gamblers, Stephanie Elaine Wemm

Legacy Theses & Dissertations (2009 - 2024)

Addictions, both substance and behavioral, have been conceptualized as having similar biopsychosocial processes with different opportunistic expressions (Shaffer et al., 2004). Biological processes such as the hormonal response to stress as measured by cortisol, dehydroepiandrosterone (DHEA), and the ratio of the DHEA/cortisol may be among the variables underlying the disposition to develop an addictive disorder, regardless of whether it is a substance-based or a so-called behavioral addiction. The current study aimed to examine whether physiological and psychological reactions to stress are similar in high-frequency smokers and gamblers. The subjective (urges, cravings) and physiological responses (skin conductance and heart rate) of …

Attitudes About Future Genetic Testing For Posttraumatic Stress Disorder And Addiction Among Community-Based Veterans., Michelle R. Lent, Stuart N Hoffman, H Lester Kirchner, Thomas G Urosevich, Joseph J Boscarino, Joseph A Boscarino

PCOM Scholarly Works

This study explored attitudes toward hypothetical genetic testing for posttraumatic stress disorder (PTSD) and addiction among veterans. We surveyed a random sample of community-based veterans (n = 700) by telephone. One year later, we asked the veterans to provide a DNA sample for analysis and 41.9% of them returned the DNA samples. Overall, most veterans were not interested in genetic testing neither for PTSD (61.7%) nor for addiction (68.7%). However, bivariate analyses suggested there was an association between having the condition of interest and the likelihood of genetic testing on a 5-point scale (p < 0.001 for PTSD; p = 0.001 for …

Resource Guide For Addiction And Mental Health Care Consumers: Answering Questions About Insurance Coverage And Parity For Addiction And Mental Health Care Services, Lucy C. Hodder, Michele D. Merritt, Margaret H. Schmidt, Jacqueline Botchman, Caitlyn Ebert, Marguerite Corvini, Kate Crary, Bridget Drake

Law Faculty Scholarship

Navigating the maze of health insurance coverage can be difficult. For individuals with addiction or mental illness, the process of getting treatment approved and paid for by health insurance can be overwhelming. As a result, many people give up when their health insurance company denies coverage for needed services. This Guide can help people learn how to access health insurance and use their coverage to pay for treatment. This Guide also provides a basic explanation of consumers’ rights under the federal Mental Health Parity and Addiction Equity Act.

Prevalence And Predictors Of Substance-Related Emergency Psychiatry Admissions, M. Scott Young, Kathleen A. Moore

Mental Health Law & Policy Faculty Publications

Background: Individuals commonly present for emergency psychiatry services for reasons related to their use of alcohol or illicit drugs. This study assessed the prevalence of these phenomena and explored characteristics distinguishing emergency psychiatry admissions with versus without presenting problems related to substance use. Methods: Data included standardized emergency psychiatry intake interviews from 2,161 consecutive admissions to three hospital-based emergency psychiatry departments in Florida’s Tampa Bay area. Admissions were classified as substanceinvolved if substance use was ascertained to be related to the presenting problem(s). Cases with only substance-related presenting problems were classified as substance-only admissions. Descriptive statistics compared substance-involved admissions to …

Perceptions Of Harm And Addiction Among Dual Users Of Cigarettes And E-Cigarettes, Julia S. Rozman

UROP Posters

Background: Tobacco harm perceptions are important factors in why individuals may initiate, substitute, and/or engage in dual or poly-tobacco use patterns. Identifying correlates of these perceptions is important for understanding why these cognitions may exist and help provide intervention targets. The purpose of the current study was to examine perceptions of harm and addiction among a sample of cigarette and electronic cigarette (e-cigarette) users and examine whether these perceptions differ by demographics, other substance use, and tobacco use history.

Methods: The current sample consisted of 29 individuals who consented to participate in a clinical laboratory study of dual cigarette and …

Exposure To Kynurenic Acid During Adolescence Increases Sign-Tracking And Impairs Long-Term Potentiation In Adulthood, Nicole E. Deangeli, Travis P. Todd, Stephen E. Chang, Hermes H. Yeh, Pamela W. Yeh, David J. Bucci

Dartmouth Scholarship

Changes in brain reward systems are thought to contribute significantly to the cognitive and behavioral impairments of schizophrenia, as well as the propensity to develop co-occurring substance abuse disorders. Presently, there are few treatments for persons with a dual diagnosis and little is known about the neural substrates that underlie co-occurring schizophrenia and substance abuse. One goal of the present study was to determine if a change in the concentration of kynurenic acid (KYNA), a tryptophan metabolite that is increased in the brains of people with schizophrenia, affects reward-related behavior. KYNA is an endogenous antagonist of NMDA glutamate receptors and …