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Articles 511 - 540 of 598
Full-Text Articles in Psychiatry and Psychology
Is Botulinum Toxin Effective At Reducing Sensory Symptoms In The Hands Of Patients With Raynaud’S Phenomenon?, Maria C. Dicioccio
Is Botulinum Toxin Effective At Reducing Sensory Symptoms In The Hands Of Patients With Raynaud’S Phenomenon?, Maria C. Dicioccio
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this systematic review is to determine, “Is Botulinum Toxin Effective at Reducing Sensory Symptoms in the Hands of Patients with Raynaud’s Phenomenon?”
Study Design: A systematic review of two randomized controlled trials (RCTs) and one prospective case series published between 2017 and 2019.
Data Sources: The articles were discovered using PubMed or Academic Search Premier. The articles were published in English in peer-reviewed journals and selected based on pertinence to the clinical question.
Outcome Measured: A reduction in sensory symptoms was the outcome measured in all three studies using the VAS pain score (0-10/100) or McCabe …
Does Hippotherapy Improve Gross Motor Function In Children With Cerebral Palsy?, Victoria I. Bockius
Does Hippotherapy Improve Gross Motor Function In Children With Cerebral Palsy?, Victoria I. Bockius
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Does hippotherapy improve gross motor function in children with cerebral palsy?”.
STUDY DESIGN: A systematic review of three randomized controlled trials (RCTs), with one being a randomized crossover trial. All three were published between 2015 and 2018.
DATA SOURCES: Three RCTs published in peer-reviewed journals were chosen from PubMed. The studies were selected based on their relevance to the clinical question.
OUTCOMES MEASURED: The outcome measured was improvement in gross motor function. Either hip adductor spasticity using Modified Ashworth Scale (MAS) or the Gross Motor Function …
Prenatal Exposure To A Natural Disaster And Early Development Of Psychiatric Disorders During The Preschool Years: Stress In Pregnancy Study, Yoko Nomura, Jeffrey H. Newcorn, Christine Ginalis, Catherine Heitz, Jeenia Zaki, Farzana Khan, Mardia Nasrin, Kathryn Sie, Donato Deingeniis, Yasmin L. Hurd
Prenatal Exposure To A Natural Disaster And Early Development Of Psychiatric Disorders During The Preschool Years: Stress In Pregnancy Study, Yoko Nomura, Jeffrey H. Newcorn, Christine Ginalis, Catherine Heitz, Jeenia Zaki, Farzana Khan, Mardia Nasrin, Kathryn Sie, Donato Deingeniis, Yasmin L. Hurd
Publications and Research
Background: Growing evidence shows an association between in utero exposure to natural disasters and child behavioral problems, but we still know little about the development of specific psychopathology in preschool-aged children. Methods: Preschool children (n = 163, mean age = 3.19, 85.5% racial and ethnic minorities) and their parents (n = 151) were evaluated annually at ages 2–5 to assess the emergence of psychopathology using the Preschool Age Psychopathological Assessment (PAPA), a parent-report structured diagnostic interview developed for preschool-age children. Sixty-six (40.5%) children were exposed to Sandy Storm (SS) in utero and 97 (59.5%) were not. Survival analysis evaluated patterns …
Intensive Outpatient Acceptance And Commitment Therapy With Exposure And Response Prevention For Adolescents, Julie M. Petersen, Patricia Zurita Ona, Moorea Blythe, Clara M. Möller, Michael P. Twohig
Intensive Outpatient Acceptance And Commitment Therapy With Exposure And Response Prevention For Adolescents, Julie M. Petersen, Patricia Zurita Ona, Moorea Blythe, Clara M. Möller, Michael P. Twohig
Psychology Student Research
Intensive treatments for youth obsessive-compulsive disorder (OCD) are important and underresearched. This study used three adolescent cases to assess the preliminary efficacy of an intensive treatment combining acceptance and commitment therapy (ACT) with exposure and response prevention (ERP) for OCD. Participants received intensive treatment for 15 hours per week for three weeks. Assessments were collected at pre-treatment, weekly during treatment, and at posttreatment. All participants ended treatment in the mild range of OCD severity with 32-60% reductions in symptoms. Participants also reported notable improvements in psychological flexibility and ended treatment in the non-clinical range of depression, anxiety, and stress. These …
Development And Validation Of A New Methodological Platform To Measure Behavioral, Cognitive, And Physiological Responses To Food Interventions In Real Time, M.A. Vargas-Alvarez, H. Al-Sehaim, J.M. Brunstrom, G. Castelnuovo, S. Navas-Carretero, J.A. Martínez, E. Almiron-Roig
Development And Validation Of A New Methodological Platform To Measure Behavioral, Cognitive, And Physiological Responses To Food Interventions In Real Time, M.A. Vargas-Alvarez, H. Al-Sehaim, J.M. Brunstrom, G. Castelnuovo, S. Navas-Carretero, J.A. Martínez, E. Almiron-Roig
Articles
To fully understand the causes and mechanisms involved in overeating and obesity, measures of both cognitive and physiological determinants of eating behavior need to be integrated. Effectively synchronizing behavioral measures such as meal micro-structure (e.g., eating speed), cognitive processing of sensory stimuli, and metabolic parameters, can be complex. However, this step is central to understanding the impact of food interventions on body weight. In this paper, we provide an overview of the existing gaps in eating behavior research and describe the development and validation of a new methodological platform to address some of these issues. As part of a controlled …
A Novel Framework To Estimate Cognitive Impairment Via Finger Interaction With Digital Devices, Ashley A Holmes, Shikha Tripathi, Emily Katz, Ijah Mondesire-Crump, Rahul Mahajan, Aaron Ritter, Teresa Arroyo-Gallego, Luca Giancardo
A Novel Framework To Estimate Cognitive Impairment Via Finger Interaction With Digital Devices, Ashley A Holmes, Shikha Tripathi, Emily Katz, Ijah Mondesire-Crump, Rahul Mahajan, Aaron Ritter, Teresa Arroyo-Gallego, Luca Giancardo
Faculty, Staff and Student Publications
Measuring cognitive function is essential for characterizing brain health and tracking cognitive decline in Alzheimer's Disease and other neurodegenerative conditions. Current tools to accurately evaluate cognitive impairment typically rely on a battery of questionnaires administered during clinical visits which is essential for the acquisition of repeated measurements in longitudinal studies. Previous studies have shown that the remote data collection of passively monitored daily interaction with personal digital devices can measure motor signs in the early stages of synucleinopathies, as well as facilitate longitudinal patient assessment in the real-world scenario with high patient compliance. This was achieved by the automatic discovery …
Family Structure And Maternal Depressive Symptoms: A Cross-National Comparison Of Australia, The United Kingdom, And The United States, Kirsten Rasmussen, Elizabeth K. Sigler, Sadie A. Slighting, Jonathan A. Jarvis, Mikaela J. Dufur, Shana Pribesh
Family Structure And Maternal Depressive Symptoms: A Cross-National Comparison Of Australia, The United Kingdom, And The United States, Kirsten Rasmussen, Elizabeth K. Sigler, Sadie A. Slighting, Jonathan A. Jarvis, Mikaela J. Dufur, Shana Pribesh
Educational Leadership & Workforce Development Faculty Publications
The purpose of this study is to understand the relationship between family structure and maternal depressive symptoms (MDS) in Australia, the United Kingdom, and the United States. Family structures that involve transitions across life's course, such as divorce, can alter access to resources and introduce new stressors into family systems. Using the stress process model, we examine the links between family structure, stress, resources, and MDS. Using nationally representative data from Australia, the United Kingdom, and the United States and cross-sectional models for each country, we find that family structure may influence MDS differently in the UK than it does …
Bolstering The Effectiveness Of Exposure-Response Prevention In The Treatment Of Obsessive-Compulsive Disorder: Using Self-Compassion As An Adjunctive Intervention, Whitney E. Dyer
DSW Capstone Projects
Individuals suffering with Obsessive-Compulsive Disorder (OCD) face many challenges receiving proper diagnostics and evidence-based treatment. Furthermore, Exposure-Response Prevention (ERP), the empirically supported gold standard approach for targeting OCD, presents its own challenges. Examining the influences of ERP treatment reluctance is paramount to bolstering the effectiveness of outcomes and safeguarding participant adherence and ultimate success. This Capstone highlights the overlooking of addressing shame within traditional ERP protocol and posits a practice application model that supports the adjunctive use of self-compassion, a potent antidote for shame, within the use of ERP. As treatment hesitation is an inhibitor to relief for OCD sufferers, …
Parental Barriers Toward Seeking Mental Healthcare For Saudi Children At Risk Of Adhd, Amani Kappi
Parental Barriers Toward Seeking Mental Healthcare For Saudi Children At Risk Of Adhd, Amani Kappi
Theses and Dissertations--Nursing
Attention deficit hyperactivity disorder (ADHD) is a mental health disorder commonly diagnosed in childhood. Underdiagnosis and undertreatment of ADHD can lead to the development of other mental illnesses and disruptions in social functioning in adulthood. Therefore, parents can play a crucial role in proactively seeking mental healthcare for children who are at risk for or who have a clear diagnosis of ADHD. Studies in the United Kingdom and the United States highlight many barriers that prevent parents from seeking mental healthcare for their children, such as negative attitudes towards the mental healthcare system and stigma towards mental illnesses.
Cultural differences …
Building Tools For Improved Modulation Of The Human Gabaa Receptor, A Central Nervous System Target For The Treatment Of Anxiety, Garrett Edward Zinck
Building Tools For Improved Modulation Of The Human Gabaa Receptor, A Central Nervous System Target For The Treatment Of Anxiety, Garrett Edward Zinck
Theses and Dissertations--Pharmacy
In the U.S., anxiety is recognized as an increasing range of mentally and physically debilitating psychiatric health disorders with significant economic repercussions. Over the last 20 years, several novel anti-anxiety therapies have entered the drug development pipeline, but none have made it to market.
The work in this dissertation focused on structurally modifying valerenic acid (VA), a structurally unique carboxylated sesquiterpene acid found in Valeriana officinalis. VA is putatively reported to have allosteric modulatory activity of the human GABAA receptor, a ligand-gated ion channel responsible for attenuating neurotransmissions. Structural modeling of VA’s GABAA receptor interaction suggests that …
Let’S Have A Playdate! Comparing Autistic Children's Social Behavior During Play Sessions With Siblings Versus Peers, Clare Boldt
Let’S Have A Playdate! Comparing Autistic Children's Social Behavior During Play Sessions With Siblings Versus Peers, Clare Boldt
Scripps Senior Theses
Autistic individuals can struggle with social interactions and forming friendships. While siblings and peers are used for social skills intervention, there is a paucity of research analyzing differences in autistic children’s play with siblings versus peers. Investigating these behavior differences helps clinicians learn how to best support social skill development, improve sibling relationships, and determine ideal peer mediators for interventions. I compare social behaviors of autistic children during play sessions with their sibling versus a non-sibling peer. The behaviors measured were prosocial behaviors, cooperative and parallel play, verbalizations (appropriate and inappropriate), aggressive behaviors, eloping, and stereotypy. Based on previous literature, …
J Mich Dent Assoc January 2022
J Mich Dent Assoc January 2022
The Journal of the Michigan Dental Association
Monthly, The Journal of the Michigan Dental Association brings news, information, and feature articles to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists! In this January 2022 issue, the reader will find the following original content:
- A cover feature, “Eating Disorders in Adolescents: Facts and Recommendations for the Oral Health Team”
- An introduction to the Pediatric Health Series, “Psychosocial Factors of COVID-19 Impact Oral Health”
- A DEI Feature, “Inclusion of the Mobility Impaired in Our Community”
- A 10-Minute EBD, “Factors Impacting Gingival Margin Position Following Esthetic Crown Lengthening”
- News you need, an …
Ambiguous Genitalia: A Medical, Surgical, Psychiatric And Ethical Concern, Saachi M. Khanna, Anoush Sardesai Sadat, Ranjani Rammohan, Sundeep Payyanur Thotan
Ambiguous Genitalia: A Medical, Surgical, Psychiatric And Ethical Concern, Saachi M. Khanna, Anoush Sardesai Sadat, Ranjani Rammohan, Sundeep Payyanur Thotan
Manipal Journal of Medical Sciences
Disorders of Sexual Differentiation or DSDs are congenital anomalies which lead to the abnormal development of the internal and external genitalia. Our main objective in this review was to bring to light the psychiatric side of healthcare for a patient with ambiguous genitalia and DSD and create more awareness of the ethical aspects of the condition. The most important step in the management of DSD is the avoidance of prematurely designating sex or using gendered pronouns, as well as reassuring the family. Treatment is not singular, but a multidisciplinary approach. It involves medical management and surgical correction of the genitalia. …
Psychosocial Factors Of Covid-19 Impact Oral Health, Neeru Ramaswami Bds, Ms, Mph
Psychosocial Factors Of Covid-19 Impact Oral Health, Neeru Ramaswami Bds, Ms, Mph
The Journal of the Michigan Dental Association
The impact of psychosocial factors on oral health during the COVID-19 pandemic necessitates an interdisciplinary approach to patient care. This article, part of National Children’s Dental Health Month, focuses on adolescent oral health and eating disorders, authored by experts from the University of Michigan. With a dramatic increase in eating disorders among Michigan adolescents during the pandemic, especially affecting transgender and diverse youth, identifying such issues is crucial. General dentists, in an ideal position for interaction, can play a vital role in addressing these challenges, emphasizing the need for continued education and collaboration.
Covid-19 Restrictions And Psychological Well-Being Of Fathers With Infants Admitted To Nicu—An Exploratory Cross-Sectional Study, Esther Abena Adama, Flora Koliouli, Livio Provenzi, Nancy Feeley, Edwin Van Teijlingen, Jillian Ireland, Frances Thomson-Salo, Minesh Khashu, Finesse Group
Covid-19 Restrictions And Psychological Well-Being Of Fathers With Infants Admitted To Nicu—An Exploratory Cross-Sectional Study, Esther Abena Adama, Flora Koliouli, Livio Provenzi, Nancy Feeley, Edwin Van Teijlingen, Jillian Ireland, Frances Thomson-Salo, Minesh Khashu, Finesse Group
Research outputs 2022 to 2026
Aim
To describe the impact of the COVID-19 restrictions on the caregiving activities and psychological well-being of fathers with infants admitted to neonatal units.
Methods
Cross-sectional study using adapted COPE-IS and COPE-IU tools. Participants' recruitment occurred online via social media and parents' associations. Online survey in English, French and Italian were distributed and promoted via websites and social media platforms of parent's associations. The study was undertaken across 12 countries in Asia, Australia, Africa and Europe.
Results
A total of 108 fathers of NICU infants completed the survey. COVID-19 related restrictions were categorised into 3 types: no restrictions, partial and …
Congenital Anomaly Epidemiological Correlates Of Δ8thc Across Usa 2003–16: Panel Regression And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
Congenital Anomaly Epidemiological Correlates Of Δ8thc Across Usa 2003–16: Panel Regression And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse
Research outputs 2022 to 2026
Δ8-Tetrahydrocannabinol (Δ8THC) is marketed in many US states as ‘legal weed’. Concerns exist relating to class-wide genotoxic cannabinoid effects. We conducted an epidemiological investigation of Δ8THC-related genotoxicity expressed as 57 congenital anomaly (CA) rates (CARs) in the USA. CARs were taken from the Centers for Disease Control, Atlanta, Georgia. Drug exposure data were taken from the National Survey of Drug Use and Health, with a response rate of 74.1%. Ethnicity and income data were taken from the US Census Bureau. National cannabinoid exposure was taken from Drug Enforcement Agency publications and multiplied by state cannabis use data to derive state-based …
Putative Mechanisms Underlying The Antidepressant Actions Of Ketamine: A Review And Study Proposal, Tristan Reece
Putative Mechanisms Underlying The Antidepressant Actions Of Ketamine: A Review And Study Proposal, Tristan Reece
CMC Senior Theses
Major Depressive Disorder (MDD) is a highly debilitating and common psychiatric disorder that affects over 250 million people globally; it is among the most financially and emotionally burdensome illnesses in the world. Currently approved antidepressants are suboptimal in their efficacy and latency of therapeutic action. In contrast, single administrations of sub-anesthetic ketamine have been shown to rapidly alleviate depressive symptoms within hours, even in treatment-resistant patients. Ketamine is believed to exert these effects by increasing glutamatemediated neurotransmission and promoting rapid neurotrophic factor release, restoring the integrity of neural circuits that are compromised in depression. However, uncertainty surrounding its specific antidepressant …
Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White
Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White
Honors Theses and Capstones
Chronic pain is a significant and widely prevalent health condition which requires comprehensive care to address the many facets contributing to symptomatology. In 2016, 20% of American adults (about 50 million) reported experiencing chronic pain, of which 7.4% indicated that chronic pain frequently limited their life and participation in activities within the past 3 months (CDC, 2018). As a result, many individuals with chronic pain turn to opioid-based medication for pain relief, but long-term use of opioids actually increases pain sensation (Tobin, 2019). Moreover, opioid medication is unable to target underlying mental health components which emerge as part of chronic …
Equine Assisted Psychotherapy: Implications For Treating Trauma, Kara L. Harrison Psy.D.
Equine Assisted Psychotherapy: Implications For Treating Trauma, Kara L. Harrison Psy.D.
Psychology Doctoral Specialization Projects
Trauma related symptoms and Posttraumatic Stress Disorder (PTSD) have been increasingly recognized for the key roles they occupy in mental health and overall individual well-being within both adult and childhood populations. They often represent significant barriers to the provision of mental healthcare within military populations and individuals diagnosed with serious mental illness (SMI). This original contribution to practice explores the significance of Equine Assisted Psychotherapy as a novel adjunctive approach to treating trauma. symptoms in adults and children. An extensive literature review examines current research and discussion on common definitions and nomenclature. It begins with discussion on the broader areas …
A Preliminary Validation Of The Polish Version Of The Comprehensive Intellectual Humility Scale (Cihs), Zdzisław Kroplewski, Elizabeth J. Krumrei-Mancuso, Grażyna Bielecka, Małgorzata Szcześniak
A Preliminary Validation Of The Polish Version Of The Comprehensive Intellectual Humility Scale (Cihs), Zdzisław Kroplewski, Elizabeth J. Krumrei-Mancuso, Grażyna Bielecka, Małgorzata Szcześniak
All Faculty Open Access Publications
Background: In the last few years, empirical research on intellectual humility has grown notably, involving the elaboration of promising measures that provide a different outlook on the construct. Although all of them offer valid, theoretically sound, and meaningful contributions, we selected the 22-item Comprehensive Intellectual Humility Scale (CIHS) by Krumrei-Mancuso and Rouse for validation. The rationale for choosing this questionnaire for Polish validation stands in its multidimensional nature, which enables the study of various nuances of this psychological concept. Methods: The research was carried out with the participation of 260 adults (Study 1) and 210 adults (Study 2). The respondents …
Interactions Of International Pilots' Stress, Fatigue, Symptoms Of Depression, Anxiety, Common Mental Disorders And Wellbeing, Marion Venus, Martin Grosse Holtforth
Interactions Of International Pilots' Stress, Fatigue, Symptoms Of Depression, Anxiety, Common Mental Disorders And Wellbeing, Marion Venus, Martin Grosse Holtforth
International Journal of Aviation, Aeronautics, and Aerospace
Objective
This study Investigates more dimensions than previous studies simultaneously: pilots’ duty rosters, stress, sleep difficulties, fatigue levels, wellbeing, symptoms of depression, anxiety, and common mental disorders (CMD), and how they are interrelated.
Background
Several scientific studies have confirmed that fatigue can pose a significant risk to flight safety. Other studies reported positive depression screening results for more pilots, compared with the general population.
Method
A cross-sectional online survey was completed by 406 international pilots, who reported their duty rosters of the last two months. Pilots also self-assessed their stress-levels, sleep problems, fatigue, wellbeing, and mental health.
Results
Although pilots …
Comparison Of Schedules, Stress, Sleep Problems, Fatigue, Mental Health And Well-Being Of Low Cost And Network Carrier Pilots, Marion Venus
Comparison Of Schedules, Stress, Sleep Problems, Fatigue, Mental Health And Well-Being Of Low Cost And Network Carrier Pilots, Marion Venus
International Journal of Aviation, Aeronautics, and Aerospace
Objective
This research investigates and compares working-conditions, duty rosters, stress, sleep problems, fatigue levels, mental health, and well-being of pilots working for network (NWCs), and low-cost carriers (LCCs). This study extends previous research by investigating working conditions, pilots’ actual rosters, fatigue and mental health of two groups of pilots flying for LCC or NWC.
Method
A comprehensive cross-sectional online survey was completed by N=338 pilots (185 NWC, 153 LCC pilots). All pilots reported their roster data of the last 2 months during peak flight season, psychosocial and work-related stress (e.g., high job insecurity, less total flight-experience, lower income, more time …
Racial Identity, Hair Esteem, Hair Texture, And Hairstyle Choice As Correlates Of Psychological Well-Being Among Afro-Latinas In The United States, Marielsy Esther Pimentel
Racial Identity, Hair Esteem, Hair Texture, And Hairstyle Choice As Correlates Of Psychological Well-Being Among Afro-Latinas In The United States, Marielsy Esther Pimentel
Dissertations
Problem
During the Colonial period, hair was one of the designated phenotypic markers of racial group membership used to assign or deny privilege. Privileges are still assigned to people based on their racial group membership and their proximity to Whiteness. As such, Hair remains a salient part of Afro-Latina women’s lives and identities, with its influences seen in the personal, social, and mental realms. How an Afro-Latina wears her hair can have legal, social, and intrapersonal consequences. The subsequent treatment of Afro-Latinas because of their hairstyle can affect how they view themselves and even how they relate to others, especially …
Perceived Instability, Pain, And Psychological Factors Predict Function And Disability In Individuals With Chronic Ankle Instability, Ashley M.B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Jessica C. Martinez, Ryan S. Mccann
Perceived Instability, Pain, And Psychological Factors Predict Function And Disability In Individuals With Chronic Ankle Instability, Ashley M.B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Jessica C. Martinez, Ryan S. Mccann
Rehabilitation Sciences Faculty Publications
Context:
Chronic ankle instability (CAI) is associated with residual instability, pain, decreased function, and increased disablement. Injury-related fear has been associated with CAI, although its relationship to other impairments is unclear. The Fear-Avoidance Model is a theoretical framework hypothesizing a relationship between injury-related fear, chronic pain, pain catastrophizing, and disability. It has been useful in understanding fear's influence in other musculoskeletal conditions but has yet to be studied in those with CAI.
Objective:
To explore relationships between instability, pain catastrophizing, injury-related fear, pain, ankle function, and global disability in individuals with CAI.
Design:
Cross-Sectional Study
Setting:
Anonymous online survey
Patients …
Healing Sanctuary, Kammy Downs
Healing Sanctuary, Kammy Downs
Master's Theses or Doctor of Nursing Practice
The natural world has hidden wisdom and resources that are disregarded as we misuse our responsibility to care for them. The benefits of being in tune with nature have been traded for a culture that manipulates nature on the altar of expediency, waste, and unquenchable desire. Healing Sanctuary presents a duality. My work speaks about the relationship between the seen and unseen, represented by ten larger-than-life drawings of medicinal herbal plants that have had a profound physical healing effect on me. At the same time, plants, roots, and seeds create visceral metaphors for mental health. Our accomplishments, outlook on life, …
Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles
Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles
Graduate Research Posters
Background: We have shown modulations in glycogen synthase kinase 3 beta (GSK3B) abundance or activity regulate ethanol consumption, suggesting potential as a therapeutic target for alcohol use disorder (AUD). Here we report the GSK3B inhibitor tideglusib’s actions on ethanol consumption, basal behaviors, and modulation of GSK3B targets.
Methods: C57BL/6J males and females received i.g. 200mg/kg tideglusib, except drinking-in-the-dark (males;100mg/kg i.p.). Drinking-in-the-dark (DID): Mice given 20% ethanol 4-hours, 4-days/week x 3 weeks and then i.p. tideglusib or vehicle x 4 days in a Latin Square design with ethanol consumption measured daily. Light/Dark Box: Mice gavaged with tideglusib or vehicle …
Transforming Hurt Boys Into Restored Men: The Lack Of Mental Health Treatment For Black Male Trauma Survivors, Shericka Danielle Smith
Transforming Hurt Boys Into Restored Men: The Lack Of Mental Health Treatment For Black Male Trauma Survivors, Shericka Danielle Smith
DSW Capstone Projects
Trauma affects individuals differently, but the prevalence of trauma and its impact on Black males is detrimental. Black males are at higher risk for posttraumatic stress disorder (PTSD), depression, substance abuse, and violent crimes when trauma is left untreated by a mental health professional. As the number of traumatic events experienced by Black males continues to rise, the number of these males who seek mental health treatment remains stagnant and painfully low. Many factors play into these behaviors, yet very little data exists on what is being done to change them.
Product one is a systematic literature review in which …
Youtube, Cyberbullying And Covid-19, Ani Shavliashvili
Youtube, Cyberbullying And Covid-19, Ani Shavliashvili
Dissertations and Theses
The purpose of this research is to uncover how people discuss bullying or cyberbullying experiences via YouTube videos before and after the start of the COVID-19 pandemic. Since people were indoors during the pandemic, individuals took to social media and left comments on YouTube about bullying. Since people could not discuss bullying in-person, it was interesting to see how people shared their views on bullying and cyberbullying via YouTube, as well as how that might have changed after the start of COVID-19. The purpose of this study is to demonstrate how social media platforms like YouTube provide a safe space …
Quality Of Life Before And After Cosmetic Surgery: Should Body Dysmorphic Disorder Be Considered An Absolute Or Relative Contraindication For Cosmetic Surgery?, Lindsay Conlisk
Capstone Showcase
Body Dysmorphic Disorder (BDD) has historically been regarded as a strong contraindication for cosmetic plastic surgery. New research now suggests that the contraindications to cosmetic surgery in patients with BDD may not be so absolute. This paper reviews diagnostic criteria, diagnostic challenges, and current standard of treatment of BDD. It then presents the idea of insight analysis in the BDD patient as a significant factor in determining if patients with BDD may or may not benefit from cosmetic surgery or procedures.
How Religion & Acceptance Affect Attachment: The Impact Of Familial Factors On Lgb Youth, Emily Stine
How Religion & Acceptance Affect Attachment: The Impact Of Familial Factors On Lgb Youth, Emily Stine
Capstone Showcase
Growing up a member of the lesbian, gay, and bisexual (LGB) community comes with its own distinct struggles. Whether it be attempting to integrate an LGB sexual identity with a religious identity, or coming out to friends and family members, there are multiple opportunities for an LGB individual to experience rejection. This rejection, or fear of potential rejection, can detrimentally impact someone’s mental health. As LGB identities are becoming more accepted overall, LGB youth tend to come out earlier. As a result, the coming out experience often coincides with a particularly turbulent time in their social and emotional development. One …