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2020

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Articles 301 - 330 of 375

Full-Text Articles in Psychiatry and Psychology

Political Centrism, Perspective Taking, And Outgroup Derogation: An Integrated Model, David Kesler Jan 2020

Political Centrism, Perspective Taking, And Outgroup Derogation: An Integrated Model, David Kesler

Murray State Theses and Dissertations

Abstract

The relationship between perspective taking abilities, political centrism, and outgroup derogation is not defined at this time. While previous research has demonstrated a negative relationship between political centrism and outgroup derogation (Van Prooijen, Krouwel, Boiten, & Eendebak, 2015), the relationship between the other variables is unclear. Therefore, the current study sought to measure the relationship between (1) perspective taking abilities and political centrism, (2) perspective taking and outgroup derogation, (3) political centrism and outgroup derogation and lastly, (4) whether the relationship between perspective taking abilities and political outgroup derogation would be mediated by an individual's level of political centrism.


The Relationship Between General Anxiety, Social Physique Anxiety, And Body Image In Collegiate Athletes And Non-Athletes, Jessica Nugent Jan 2020

The Relationship Between General Anxiety, Social Physique Anxiety, And Body Image In Collegiate Athletes And Non-Athletes, Jessica Nugent

West Chester University Master’s Theses

Context: Due to the clinical significance, it is important that anxiety is identified early in collegiate athletes. Unlike the extensive amount of research done conducted on mental health in the general population, there is minimal research examining the mental health of athletes. The relationship between general anxiety (GAD), social physique anxiety (SPA), and body image (BI) in this population has not been studied. Objective: To examine the relationship between general anxiety, social physique anxiety, and body image in collegiate athletes and non-athletes. Design: Cross-sectional quantitative study. Setting: One NCAA Division II University. Participants: Three hundred and eleven students participated in …


Binegative Minority Stress, Psychological Processes, And Disordered Alcohol Use: Disparities Among Sexual Minority Womxn, Kinsie Jean Dunham Jan 2020

Binegative Minority Stress, Psychological Processes, And Disordered Alcohol Use: Disparities Among Sexual Minority Womxn, Kinsie Jean Dunham

Graduate Student Theses, Dissertations, & Professional Papers

Sexual minority womxn (i.e., woman-identified persons) tend to report more harmful alcohol use and more negative alcohol use outcomes than heterosexual women—a pattern not consistently observed in man-identified populations. Further, bisexually-oriented, hereafter called nonexclusively-oriented, womxn (NOW) report more negative alcohol use outcomes and meet criteria for alcohol use disorder at higher rates than both lesbians and heterosexual women (or exclusively-oriented womxn; EOW). These disparities require further investigation to explicate the antecedents and mechanisms impacting alcohol use for this at-risk population. This project examines the incremental negative effects of binegativity as a specific minority stressor and antecedent of disordered alcohol use. …


Transcriptomic Profiling Of Postmortem Prefrontal Cortex And Nucleus Accumbens From Chronic Alcohol Abusers., Eric S. Vornholt Jan 2020

Transcriptomic Profiling Of Postmortem Prefrontal Cortex And Nucleus Accumbens From Chronic Alcohol Abusers., Eric S. Vornholt

Theses and Dissertations

Alcohol use disorder (AUD) is a debilitating psychiatric illness that develops from a combination of genetic and environmental factors. While it is well documented that AUD is heritable, the shift from recreational alcohol use to abuse/dependence is poorly understood. In this dissertation, using postmortem brain tissue from individuals with alcohol dependence (AD), we profiled the genome-wide expression of circular RNA (circRNA), microRNA (miRNA), and messenger RNA (mRNA) to better understand the impact of gene expression on the development of AUD. To achieve this, we performed two independent studies that explore transcriptome differences between AD cases and controls. The first of …


Mindfulness Training's Effect On Stress, Attention, And Perfectionism And Their Relationship To Achievement Goals, Alexandra Lesniak Jan 2020

Mindfulness Training's Effect On Stress, Attention, And Perfectionism And Their Relationship To Achievement Goals, Alexandra Lesniak

Undergraduate Honors Theses

In recent years, the practice of cultivating mindfulness, a nonjudgmental awareness of the present moment, has made a resurgence in areas ranging anywhere from behavioral issues to work and academic productivity (Brown & Ryan, 2003a). The current study was focused on the relationships between mindfulness, achievement styles, stress, attention, and perfectionism at a single-sex, liberal arts institution. One hundred and five undergraduate, female students participated in this study. All participants were randomly assigned to either a mindfulness audio condition or a badminton audio condition as a control. Then, they were given measures relating to achievement goals, mindfulness capability, state mindfulness, …


The Psychological Undertones For Delayed And Non-Treatment Seeking Behavior After Concussion, Nicholas G. Debellis Jan 2020

The Psychological Undertones For Delayed And Non-Treatment Seeking Behavior After Concussion, Nicholas G. Debellis

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Title: Psychological Undertones for Delayed or Non-responding After Concussion.

The topic of my research project focuses on mild traumatic brain injury (concussion) and the reason that people delay or simply never seek treatment after sustaining an injury.

Purpose: The goal of this project is to gain a general understanding for why individuals don’t seek or delay seeking help after sustaining a concussion. We believe that this project is important for helping us to identify why people don't seek treatment while shedding light on the dark figure that exists within mental health and sports culture. We hold that the data gathered …


Alterations In Corticotropin-Releasing Factor Receptor Type 1 In The Hypothalamus And Preoptic Area During The Postpartum Period, Rose Ann M. De Guzman Jan 2020

Alterations In Corticotropin-Releasing Factor Receptor Type 1 In The Hypothalamus And Preoptic Area During The Postpartum Period, Rose Ann M. De Guzman

Legacy Theses & Dissertations (2009 - 2024)

Despite the apparent sex difference in prevalence of anxiety in humans, pre-clinical studies that have led to anxiolytic drug discoveries between 1960 and 2012 used male animals and approximately 6% of 10,000 studies used female animals. The generalizability of the efficacy of these drugs to both sexes may be limited if data derived are predominantly based on the male brain. The purpose of this dissertation, therefore, was to investigate potential underlying neuronal mechanisms that could be contributing to the sex differences in stress-related mood disorder prevalence and to focus on shedding light on female brains.


Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens Jan 2020

Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens

Computer Science Faculty Publications

Background: Although there have been increasing reports of intentional gabapentin misuse, epidemiological evidence for the phenomenon is limited. The purpose of this study was to determine whether there are pharmacovigilance abuse signals for gabapentin.

Methods: Using FDA Adverse Events Reporting System reports from January 1, 2005 to December 31, 2015, we calculated pharmacovigilance signal measures (i.e., reporting odds ratio, proportional reporting ratio, information component, and empirical Bayes geometric mean) for abuse-related adverse event (AR-AE)-gabapentin pairs. Loglinear modeling assessed the frequency of concurrent reporting of abuse-related and abusespecific AEs (AS-AEs) associated with gabapentin. Findings were compared to a positive (pregabalin) and …


Proceedings Of The 2020 Undergraduate Research Conference, Ryan C. Winters, Baylee E. Guillory, Baton Rouge Community College, Grambling State University, Louisiana College, Louisiana State University, Mcneese State University, Northwestern State University Of Louisiana, Southern University And A&M College, University Of Louisiana At Lafayette Jan 2020

Proceedings Of The 2020 Undergraduate Research Conference, Ryan C. Winters, Baylee E. Guillory, Baton Rouge Community College, Grambling State University, Louisiana College, Louisiana State University, Mcneese State University, Northwestern State University Of Louisiana, Southern University And A&M College, University Of Louisiana At Lafayette

Advance: Student Research Experience

Proceedings of the 2020 Undergraduate Research Conference, University of Louisiana at Lafayette, November 9-10, 2020.


From Urges To Action: Negative Urgency And Nonsuicidal Self-Injury In An Acute Transdiagnostic Sample, Andrew D. Peckham, Haley Jordan, Alexandra Silverman, Stephanie Jarvi Steele, Theöstur Björgvinsson, Courtney Beard Jan 2020

From Urges To Action: Negative Urgency And Nonsuicidal Self-Injury In An Acute Transdiagnostic Sample, Andrew D. Peckham, Haley Jordan, Alexandra Silverman, Stephanie Jarvi Steele, Theöstur Björgvinsson, Courtney Beard

Psychology: Faculty Publications

Urgency–rash action during strong emotion–is a robust correlate of nonsuicidal self-injury (NSSI). This study tested whether urgency is associated with time between NSSI urges and NSSI, and sought to replicate the finding that urgency is associated with NSSI history. Participants attending a partial hospitalization program (N = 669) completed self-report measures of urgency, NSSI history and latency, and psychiatric symptoms. Consistent with previous research in clinical samples, rates of lifetime engagement in NSSI were high. Using logistic regression to predict short vs. long latency between urges and NSSI, no significant relationship emerged between negative urgency and latency to self-injure. Negative …


Complex Morphology In Romani Can Resolve The Ambiguity Of Multiple Possessives, Jill De Villiers, Huseyin Kyuchuk, Tyler Poisson Jan 2020

Complex Morphology In Romani Can Resolve The Ambiguity Of Multiple Possessives, Jill De Villiers, Huseyin Kyuchuk, Tyler Poisson

Psychology: Faculty Publications

From the 44th annual Boston University Conference on Language Development, held November 7-10, 2019


Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan Jan 2020

Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan

CMC Senior Theses

Eating disorders are an increasingly prevalent issue, especially among young women. While they aren’t a new phenomenon, they are historically under-researched, and remain widely misunderstood. Without understanding the causes underlying these disorders or the mechanisms working to maintain them, treating them successfully has proved to be incredibly difficult. This is especially the case with Anorexia Nervosa. Out of the six eating disorders in the DSM-5, it has the lowest treatment success rate and an alarmingly high relapse rate. Treating the disorder through weight restoration and the extinction of compensatory behaviors alone does not fully resolve the disordered pathology; interpersonal problems …


The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio Jan 2020

The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio

Honors Theses and Capstones

Social media use has increased substantially in recent years, and for the college-aged population, social media is often the leading method of communication. Research indicates this reliance on digital connection could have a negative impact on the health of young adults (Bagroy et al., 2017). The college years are a time of personal growth and defining actions, yet can also be burdened by mental health issues related to stress, anxiety, and depression (Hunt & Eisenberg, 2010). Acknowledging these trends, the current study explores how college students’ specific frequency and intentionality while interacting on social media relates to their psychological well-being. …


Changing The Subject Of Sati, Deepa Das Acevedo Jan 2020

Changing The Subject Of Sati, Deepa Das Acevedo

Faculty Articles

Charan Shah's 1999 death was widely considered to be the first sati, or widow immolation, to have occurred in India in over twenty years. Media coverage of the event focused on procedural minutiae-her sari, her demeanor-and ultimately, several progressive commentators came to the counterintuitive conclusion that the ritually anomalous nature of Charan's death confirmed its voluntary, secular, and noncriminal nature. This article argues that the "unlabeling" of Charan's death, like those of other women between 1999 and 2006, reflects a tension between the nonindividuated, impervious model of personhood exemplified by sati and the particularized citizen-subject of liberal-democratic politics in India.


Tobacco Use Disparities By Sexual And Gender Minority Status Among Ucf Students., Parth N. Patel Jan 2020

Tobacco Use Disparities By Sexual And Gender Minority Status Among Ucf Students., Parth N. Patel

Digital Repository: Showcase of Undergraduate Research Excellence

No abstract provided.


Schizophrenia Spectrum Disorders: Linking Motor And Process Skills, Sensory Patterns, And Psychiatric Symptoms, Lola Halperin, Janet Falk-Kessler Jan 2020

Schizophrenia Spectrum Disorders: Linking Motor And Process Skills, Sensory Patterns, And Psychiatric Symptoms, Lola Halperin, Janet Falk-Kessler

Occupational Therapy Faculty Publications

Background: Consistent evidence suggests sensory abnormalities and skill deficits in people with Schizophrenia Spectrum Disorder (SSD). Further exploration of their sensory patterns and performance skills is warranted to promote community participation among these individuals.

Method: This study examined sensory patterns and motor and process skills in relationship to psychiatric symptoms in adult patients with SSD. Participants were evaluated using the Adolescent/Adult Sensory Profile, the Assessment of Motor and Process Skills, and the Brief Psychiatric Rating Scale.

Results: Of the 18 participants, the majority showed sensory differences, deficits in motor and process skills, and the presence of moderate to severe symptoms. …


Measuring The Effects Of Lobinaline-N-Bioxide (419) On Alcohol Consumption, Nicotine Locomotor Sensitization, And Conditioned Place Preference In Mice And Rats, Cocanut M. Suhail Jan 2020

Measuring The Effects Of Lobinaline-N-Bioxide (419) On Alcohol Consumption, Nicotine Locomotor Sensitization, And Conditioned Place Preference In Mice And Rats, Cocanut M. Suhail

Theses and Dissertations--Medical Sciences

Objective: Novel drug 419 was examined to see the effect it has in vivo mice and rats on alcohol consumption, nicotine locomotor sensitization, and conditioned place preference (CPP) models regarding behavioral tests on dopamine transporter activity.

Methods: Mice and rats were used to see how they react to the drug 419 and control vehicle, in each of the models. The animals were assessed to pre- and post- drug administration of novel drug 419. We examined each model to see the association between how drug 419 will help with treating drug abuse.

Results: We found that in alcohol consumption model the …


The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop Jan 2020

The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop

Theses and Dissertations--Pharmacy

Objectives: We investigated whether there is a measurable difference in medication utilization for psychiatric conditions before and after bone marrow transplantation (BMT). Previous studies have identified a potential association between psychiatric conditions and immune function. We hypothesized that medication utilization for psychiatric diagnoses would be impacted by BMT.

Methods: This study was a retrospective, quasi-experimental cohort design. De-identified data was compiled from the Truven database for patients ranging from January 2009 through December 2016. Two measurements of medication utilization, proportion of days covered (PDC) and medication possession ratio (MPR) were calculated for each included Medispan-defined class of medications before analyzing …


Mixed Features Specifier In Mood Disorder: The Prevalence And Associated Factors, M. Paramannantha Veloo Tesini Jan 2020

Mixed Features Specifier In Mood Disorder: The Prevalence And Associated Factors, M. Paramannantha Veloo Tesini

Student Works (2020-2029)

Introduction: Mixed episode has been an unrelieved source of discussion in the field of psychiatry over the course of two decades as the DSM-IV criteria for both a depressive and manic episode had to be fulfilled to make this diagnosis. Nevertheless, in practice, this threshold was demonstrated to be too high. Therefore, the DSM-5 introduced a less stringent ‘specifier’ in which three symptoms of the opposite pole suffice thereby creating depression and mania with mixed features, respectively. Literatures points out that approximately 40% of patients have mixed episodes, but this figure may be much higher within the context of DSM-5. …


Psychometric Properties Of Bergen Social Media Addiction Scale (Bsmas) In Malay Version, Kee Hui Romi Tiong Jan 2020

Psychometric Properties Of Bergen Social Media Addiction Scale (Bsmas) In Malay Version, Kee Hui Romi Tiong

Student Works (2020-2029)

Background The percentage of internet users in Malaysia has recorded continuous increment annually, in which it increased from 76.9% in 2016 to 87.4% of users in 2018. The prevalent use of all sorts of social media platform and the convenient access to the internet regardless of time and place has massively enhance the potential of social media addiction. After many years of research, the researchers have yet to reach the consensus in identifying criteria to diagnose problematic attachment to social media. The aim of the study was to validate the Malay version of Bergen Social Media Addiction Scale (BSMAS), by …


Psychiatric Morbidity Among Orang Asli In Bukit Lanjan, Iberahim Muhammad Ilham Jan 2020

Psychiatric Morbidity Among Orang Asli In Bukit Lanjan, Iberahim Muhammad Ilham

Student Works (2020-2029)

Prevalence of Psychiatric Morbidity Among Orang Asli In Bukit Lanjan, Selangor, Malaysia Introduction Orang Asli, the indigenous people of peninsular Malaysia, are those peoples who were born among Orang Asli, lives according to their distinguished culture and beliefs, and spoke their native languages. Malaysia has evolved rapidly over the years in the socioeconomic development especially in the rural areas. More jungle areas are open up for land development scheme such as Federal Land Development Authority (FELDA), housing projects, commercial farms and many more. Indigenous people are forced to face this rapid urbanization. The questions arise whether they are able to …


Improving Transitions In Care: Focus On The Revocation Of Conditional Discharge Process In New Hampshire, Stacy A. Sorrell Jan 2020

Improving Transitions In Care: Focus On The Revocation Of Conditional Discharge Process In New Hampshire, Stacy A. Sorrell

DNP Scholarly Projects

Background: At this time there is no standardized education for providers of New Hampshire Hospital addressing the Revocation of Conditional Discharge Process. Psychiatric patients in New Hampshire most at risk for harm to self or others are managed through Involuntary Commitment Orders. These orders are intended to support those most at risk of destabilization and treatment non-compliance. The Revocation of Conditional Discharge Process is one of the procedures used to re-hospitalize a patient whose care is managed through an Involuntary Commitment Order when needed. The psychiatric providers at New Hampshire Hospital must complete this last step in the revocation process, …


Relationship Between Iranian L2 Learners’ Intercultural Communicative Competence And Personality Traits, Mahmood Hashemian, Maryam Farhang-Ju Jan 2020

Relationship Between Iranian L2 Learners’ Intercultural Communicative Competence And Personality Traits, Mahmood Hashemian, Maryam Farhang-Ju

Khazar Journal of Humanities and Social Sciences

The rapid development of communication technologies has facilitated communication between citizens with diverse personality traits. As intercultural communicative competence (ICC) has recently found its way into L2 theory and research, not only is it important for L2 learners to gain knowledge of ICC but also it is essential to be aware of personality traits. Therefore, through investigating the (possible) relationship between ICC and personality traits, this study was an attempt to gain knowledge of L2 learners’ ICC and personality traits/types profiles. For this purpose, 165 upper-intermediate L2 learners (70 males and 95 females) participated in this study. Then, they filled …


Therapeutic Art For Individuals With Multiple Sclerosis, Alexandra Kocsik, Silva Markovic-Plese, Md, Phd Jan 2020

Therapeutic Art For Individuals With Multiple Sclerosis, Alexandra Kocsik, Silva Markovic-Plese, Md, Phd

Phase 1

Introduction: Depression is more prevalent in individuals with MS than in the average population, which presents complications of quality of life beyond simply the primary disease process. This project aims to explore the immediate emotional benefits of therapeutic art sessions for individuals with MS, in addition to exploring the feasibility of reducing concomitant depression in this population with therapeutic art alongside standard medical therapy.

Methods: Therapeutic art sessions were held with 3 support groups of 5 to 12 individuals with MS. Participants were initially prompted with a writing exercise regarding how they perceive themselves, and then prompted to paint a …


The Efficacy Of Yoga As An Adjunctive Therapy To Standard Multidisciplinary Care In The Treatment Of Female Patients Presenting With Cognitive Eating Disorder Symptoms, Cassidy Nagle Jan 2020

The Efficacy Of Yoga As An Adjunctive Therapy To Standard Multidisciplinary Care In The Treatment Of Female Patients Presenting With Cognitive Eating Disorder Symptoms, Cassidy Nagle

Capstone Showcase

Introduction: Current treatment of patients exhibiting cognitive eating disorder symptoms is standard multidisciplinary care (SMDC) involving behavioral therapy, medical management and dietetics. Because these symptoms often persist or relapse despite treatment, research has begun to explore adjunctive therapies like yoga for this population. This review will explore seven studies in order to analyze the effect of yoga (I) on cognitive eating disorder symptoms (O) in teenage and adult females (P) when added to SMDC compared to symptom reduction with SMDC alone (C).

Methods: A literature search was conducted in PubMed, Academic Search Ultimate and Google Scholar starting November 2018. Seven …


College Students’ Perceptions Of Popular Diets And Orthorexia Nervosa, Madison W. Weinstock Jan 2020

College Students’ Perceptions Of Popular Diets And Orthorexia Nervosa, Madison W. Weinstock

Theses and Dissertations

Data suggest that individuals’ purported dietary patterns influence others’ perceptions of them. However, few studies have investigated how adherence to specific popular diets might influence these perceptions. This study investigated female undergraduates’ (n = 463) perceptions of vignette characters described as adhering to specific dietary practices perceptions of a vignette character in a sample of 463 female undergraduates. Characters described as adhering to a Clean Eating diet were viewed most positively, followed by individuals on the Ketogenic diet or nondieters. Characters following an Intermittent Fasting diet, and those with Orthorexia Nervosa were viewed most negatively. These findings support the …


Mood Effects And Individual Differences On Reappraisal And Distraction: An Erp Study Of The Sensitivity Of Emotion Regulation Strategies, Elsa Mastico Jan 2020

Mood Effects And Individual Differences On Reappraisal And Distraction: An Erp Study Of The Sensitivity Of Emotion Regulation Strategies, Elsa Mastico

All Master's Theses

The present research evaluated the effect of mood and individual differences on the regulatory process of emotions by using a regulation task with negative and neutral images to assess reappraisal and distraction ability. Specifically, this research evaluated the average amplitude of the latent positive potential (latent positivity, LPP) brainwave linked to distraction and reappraisal using an ERP analysis. In addition, the current study compared the modulation of the LPP to the self-reported mood of the participants and their individual differences in regulation ability through scores of a self-report emotion regulation questionnaire. The latent positive potentials from an emotion regulation task …


A Metacognitive Triggering Mechanism For Anticipatory Thinking, Alexander R. Hough, Othalia Larue, Ion Juvina Jan 2020

A Metacognitive Triggering Mechanism For Anticipatory Thinking, Alexander R. Hough, Othalia Larue, Ion Juvina

Psychology Faculty Publications

Current autonomous systems have the ability to adapt to envi-ronmental changes in real-time, but limited ability to engage inanticipatory thinking (AT) with the flexibility to generalize andconsider hypothetical future situations. We argue that metacog-nitive processes are important for an and provide supporting lit-erature primarily from psychology. As an example, we presenta metacognitive monitoring mechanism implemented in a cog-nitive model and discuss ways to extend the mechanism to allowfor dynamic behavior and anticipatory thinking capabilities.


Analysis Of The Ethical Leadership Behaviors’ Effect On Life Satisfaction And Mediation Effect Of Organizational Commitment, Zülbiye Kaçay, Fikret Soyer, Ersin Eskiler Jan 2020

Analysis Of The Ethical Leadership Behaviors’ Effect On Life Satisfaction And Mediation Effect Of Organizational Commitment, Zülbiye Kaçay, Fikret Soyer, Ersin Eskiler

Khazar Journal of Humanities and Social Sciences

The aim of this study was to examine the effect of ethical leadership behaviours of school administrators on life satisfaction of physical education and sports teachers and the mediating effect of organizational commitment on this effect. For this purpose, in 2015-2016 academic year, the physical education and sport teachers working at a formal schools in different provinces of Turkey were determined as a research sample by preferring an easy sampling method, the data was obtained from a total of 436 physical education and sport teachers, (176 female and 259 male). In order to obtain data, online surveys (147) and face …


Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya Jan 2020

Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya

Publications and Research

IMPORTANCE Autism spectrum disorder (ASD) is highly heritable, and modest contributions of common genetic variants to ASD have been reported. However, the association of genetic risks derived from common risk variants with ASD traits in children from the general population is not clear, and the association of these genetic risks with neurodevelopment in infants has not been well understood.

OBJECTIVE To test whether a polygenic risk score (PRS) for ASD is associated with neurodevelopmental progress at age 18 months and ASD traits at age 6 years among children from the general population.

DESIGN, SETTING, AND PARTICIPANTS In this cohort study, …