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Articles 211 - 240 of 283
Full-Text Articles in Psychiatry and Psychology
Examining The Appeal And Ascribed Meanings Of Complementary And Alternative Medicine (Cam) Use By Males: An Interpretative Phenomenological Analysis, Kathryn V. Hogan
Examining The Appeal And Ascribed Meanings Of Complementary And Alternative Medicine (Cam) Use By Males: An Interpretative Phenomenological Analysis, Kathryn V. Hogan
Theses : Honours
Men are commonly and consistently underrepresented in global depression rates, however figure predominantly in rates for substance abuse and suicide. It has been suggested that men’s under-utilisation of mental health services accounts for the discrepancy between the genders and that hegemonic masculine stereotypes have created a barrier for males in seeking help for mood disorders. The use of Complementary and Alternative Medicines (CAM) has been expanding globally, with research showing in some instances of self-diagnosed depression and anxiety, CAM is being utilised more often than mainstream health care services. The present study explored the personal meanings of males who currently …
Physical, Emotional, And Competitive Aggression Tendencies In Contact And Non-Contact Collegiate Athletes, Samyra Rose Safraoui
Physical, Emotional, And Competitive Aggression Tendencies In Contact And Non-Contact Collegiate Athletes, Samyra Rose Safraoui
Online Theses and Dissertations
Differences in aggression tendencies between athletes who play a contact sport and athletes who play a non-contact sport at the collegiate level were investigated. Specifically, emotional, physical, and competitive aggression tendencies were measured for both groups and then compared to each other using independent t tests and effect sizes. One hundred student-athletes from a medium sized midwestern university participated in the study, with an even split between contact and non-contact athletes. Student-athletes were sent an electronic survey via email and Survey Monkey; all materials were approved by the university's Institutional Review Board (IRB) and Athletics department.
It was determined that …
The Role Of Positive Alcohol Expectancies In Underage Binge Drinking Among College Students, Nicole M Mcbride, Blake Barrett, Kathleen A. Moore, Lawrence Schonfeld
The Role Of Positive Alcohol Expectancies In Underage Binge Drinking Among College Students, Nicole M Mcbride, Blake Barrett, Kathleen A. Moore, Lawrence Schonfeld
Mental Health Law & Policy Faculty Publications
Objective: This study explored associations between positive alcohol expectancies, and demographics, as well as academic status and binge drinking among underage college students. Participants: A sample of 1,553 underage college students at 3 public universities and 1 college in the Southeast who completed the Core Alcohol and Drug Survey in the Spring 2013 semester. Methods: A series of bivariate analyses and logistic regression models were used to examine associations between demographic and academic status variables as well as positive alcohol expectancies with self-reported binge drinking. Positive alcohol expectancies were examined in multivariable models via 2 factors derived from principal component …
African American Families' Expectations And Intentions For Mental Health Services, Cynthia J. Najdowski, Richard Thompson, Barbara L. Dancy, Tisha R. A. Wiley, Sylvia P. Perry, Jason Wallis, Yara Mekawi, Kathleen Knafl
African American Families' Expectations And Intentions For Mental Health Services, Cynthia J. Najdowski, Richard Thompson, Barbara L. Dancy, Tisha R. A. Wiley, Sylvia P. Perry, Jason Wallis, Yara Mekawi, Kathleen Knafl
Psychology Faculty Scholarship
A cross-sectional qualitative descriptive design was used to examine the links among expectations about, experiences with, and intentions toward mental health services. Individual face-to-face interviews were conducted with a purposive sample of 32 African American youth/mothers dyads. Content analysis revealed that positive expectations were linked to positive experiences and intentions, that negative expectations were not consistently linked to negative experiences or intentions, nor were ambivalent expectations linked to ambivalent experiences or intentions. Youth were concerned about privacy breeches and mothers about the harmfulness of psychotropic medication. Addressing these concerns may promote African Americans’ engagement in mental health services.
Modeling Science And Faith Integration May Be More Powerful Than Words. Reflections On "The Study Of Science In Catholic Higher Education In The United States: A Modern Nuisance?", Thomas Plante
Psychology
In "The study of science in Catholic higher education in the United States: A modern nuisance?", Fr. Cunningham offers a thoughtful and engaging commentary on the history and state of science education in Catholic universities in the United States, carefully weaving history, science, and even politics in a seamless and multilayered manner. But before offering reflections on what he said in his paper, I'd like to make a few comments on who he is which, at the end of the day, might be actually more important.
Instruction In Functional Assessment, Marcie Desrochers, Moira Fallon
Instruction In Functional Assessment, Marcie Desrochers, Moira Fallon
Milne Open Textbooks
Instruction in Functional Assessment introduces learners to functional assessment (FA), which includes a variety of assessment approaches (indirect, observational, and experimental) for identifying the cause of an individual’s challenging behavior for the purpose of designing effective treatments. FA is mandated by federal law and is a recognized empirically based approach to treatment of individuals with challenging behaviors (e.g., disruptive, self-injurious, and aggressive behaviors). Instruction in FA is essential for students who will one day enter professions as educators, psychologists, social workers, counselors, or mental health professionals.
The purpose of this textbook is to provide instruction in FA skills for pre-professionals …
Pd_Ngsatlas: A Reference Database Combining Next-Generation Sequencing Epigenomic And Transcriptomic Data For Psychiatric Disorders, Zheng Zhao, Yongsheng Li, Hong Chen, Jianping Lu, Peter M. Thompson, Juan Cheng, Zishan Wang, Juan Xu, Chun Xu, Xia Li
Pd_Ngsatlas: A Reference Database Combining Next-Generation Sequencing Epigenomic And Transcriptomic Data For Psychiatric Disorders, Zheng Zhao, Yongsheng Li, Hong Chen, Jianping Lu, Peter M. Thompson, Juan Cheng, Zishan Wang, Juan Xu, Chun Xu, Xia Li
Health & Biomedical Sciences Faculty Publications
Background: Psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BP) are projected to lead the global disease burden within the next decade. Several lines of evidence suggest that epigenetic- or genetic-mediated dysfunction is frequently present in these disorders. To date, the inheritance patterns have been complicated by the problem of integrating epigenomic and transcriptomic factors that have yet to be elucidated. Therefore, there is a need to build a comprehensive database for storing epigenomic and transcriptomic data relating to psychiatric disorders.
Description: We have developed the PD_NGSAtlas, which focuses on the efficient storage of epigenomic and transcriptomic data based …
Child Sexual Abuse Leads To Psychological Disorders: Literature Review, Savera Aziz Ali, Sumera Aziz Ali
Child Sexual Abuse Leads To Psychological Disorders: Literature Review, Savera Aziz Ali, Sumera Aziz Ali
School of Nursing & Midwifery
This scholarly paper explains the relationship between child sexual abuse and psychological disorders. Childhood sexual abuse (CSA) is a forceful sexual contact with a child who is incapable of consenting. The impact of sexual abuse can range from physical to very severe psychological effects. Psychological disorders caused by child sexual abuse include panic disorder, anxiety, depression, substance abuse, low self-esteem and post-traumatic stress disorder. The phenomenon of child sexual abuse is shaped by some important theories like behavioral, psychodynamic, attachment, cognitive and integrated theory. These theories may help to develop a sound empirical base through which cost effective strategies can …
Firesetting And Maltreatment, Amy L. Burnett, Hatim A. Omar
Firesetting And Maltreatment, Amy L. Burnett, Hatim A. Omar
Pediatrics Faculty Publications
In this chapter we try to determine if a link exists between firesetting offenders and a past history of maltreatment. A literature review was performed using research from various studies and populations. Firesetting is a significant problem that affects the world's youth today. Even though there is substantial loss of property and life from juvenile firesetters, there is not a great deal of research to provide insight into early identification of those at risk. In the literature review performed, 6 of 7 studies found a link with maltreatment and firesetting behaviors. There does seem to be a correlation between the …
The Relationship Between Simple Pleasures And Trait Gratitude, Megan Shupe
The Relationship Between Simple Pleasures And Trait Gratitude, Megan Shupe
EWU Masters Thesis Collection
Grateful disposition is associated with positive affect, happiness, high levels of overall well-being and an appreciation of simple pleasures. This study further examined the relationship between simple pleasures and trait gratitude. I hypothesized that people with higher trait gratitude scores would notice more simple pleasures in their lives and feel more gratitude for simple pleasures than less grateful people. I acquired data from 169 undergraduate students at Eastern Washington University. Results suggested that grateful people experienced the same number of simple pleasures as less grateful people but were more grateful for them. This suggests that although grateful people do not …
Ordinary Magic: D.W. Winnicott And The E. Nesbit Tradition In Children’S Literature, Sarah Pincus
Ordinary Magic: D.W. Winnicott And The E. Nesbit Tradition In Children’S Literature, Sarah Pincus
English Honors Papers
In this thesis, I look closely at four particular children’s books as representative of a genre within children’s literature, one that I call “ordinary magic.” Whereas most children’s literature can be categorized either as realistic fiction or as fantasy, I examine a group of books that resists such classification. Drawing on the psychoanalyst D.W. Winnicott’s theory of transitional phenomena, I discuss the ways in which the novels within this genre navigate the boundaries between fantasy and realism, exploring related oppositions such as home and away, childhood and adulthood, reading and real life, and rebellion and compliance. I argue that a …
Yoga And Breathing And Relaxation Techniques Used During The School Day And Their Effects On School-Aged Children, Erica Marie Thomas
Yoga And Breathing And Relaxation Techniques Used During The School Day And Their Effects On School-Aged Children, Erica Marie Thomas
Wayne State University Theses
Physical activity during the school day is becoming more important as the health of our children stays below optimal levels. Yoga has been shown to increase physical activity levels and decrease stress. This study, guided by the Social Cognitive Theory's idea of reciprocal determinism, sought to determine the effects of a Yoga Calm® certified classroom teacher incorporating yoga poses, breathing and relaxation techniques and games into every school day. Quantitative data were analyzed using a series of paired and independent t-tests, and self-reports revealed students receiving yoga decreased scores in stress and fighting, but increased scores in anger. Qualitative data …
Affective Responses To Music Without Recognition: Beyond The Cognitivist Hypothesis, W. Trey Hill
Affective Responses To Music Without Recognition: Beyond The Cognitivist Hypothesis, W. Trey Hill
Psychology Faculty Publications
A recent topic of concern for those interested in the science of music is whether affective responses to music are the result of recognition or actual affective experience. Cognitivist researchers have found that individuals recognize rather than feel an affective response when listening to music, while emotivist proponents posit that people have an intrinsic affective experience to music. While it has been promoted that biological methods must be used in order to answer this recognition-experience problem cited above, the current authors employed a more traditional technique (i.e., paper and pencil self-report surveys). Data from the present study show that participants …
Common And Specific Impairments In Attention Functioning In Girls With Chromosome 22q11.2 Deletion, Fragile X Or Turner Syndromes., A I. Quintero, Elliott A. Beaton, Danielle J. Harvey, Judith L. Ross, Tony J. Simon
Common And Specific Impairments In Attention Functioning In Girls With Chromosome 22q11.2 Deletion, Fragile X Or Turner Syndromes., A I. Quintero, Elliott A. Beaton, Danielle J. Harvey, Judith L. Ross, Tony J. Simon
Psychology Faculty Publications
Background:
Chromosome 22q11.2 deletion syndrome (22q11.2DS), fragile X syndrome (FXS), and Turner syndrome (TS) are complex and variable developmental syndromes caused by different genetic abnormalities; yet, they share similar cognitive impairments in the domains of numbers, space, and time. The atypical development of foundational neural networks that underpin the attentional system is thought to result in further impairments in higher-order cognitive functions. The current study investigates whether children with similar higher-order cognitive impairments but different genetic disorders also show similar impairments in alerting, orienting, and executive control of attention.
Methods:
Girls with 22q11.2DS, FXS, or TS and typically developing (TD) …
Monitoring The Health Of Transgender And Other Gender Minority Populations: Validity Of Natal Sex And Gender Identity Survey Items In A U.S. National Cohort Of Young Adults, Sari L. Reisner, Kerith J. Conron, Laura Anatale Tardiff, Stephanie Jarvi Steele, Allegra R. Gordon, S Bryn Austin
Monitoring The Health Of Transgender And Other Gender Minority Populations: Validity Of Natal Sex And Gender Identity Survey Items In A U.S. National Cohort Of Young Adults, Sari L. Reisner, Kerith J. Conron, Laura Anatale Tardiff, Stephanie Jarvi Steele, Allegra R. Gordon, S Bryn Austin
Psychology: Faculty Publications
Background: A barrier to monitoring the health of gender minority (transgender) populations is the lack of brief, validated tools with which to identify participants in surveillance systems.
Methods: We used the Growing Up Today Study (GUTS), a prospective cohort study of U.S. young adults (mean age = 20.7 years in 2005), to assess the validity of self-report measures and implement a two-step method to measure gender minority status (step 1: assigned sex at birth, step 2: current gender identity). A mixed-methods study was conducted in 2013. Construct validity was evaluated in secondary data analysis of the 2010 wave (n = …
Desk Jockey: A Device To Increase Non-Exercise Activity Thermogenesis (Neat) In Adults, Jiangqi Tang
Desk Jockey: A Device To Increase Non-Exercise Activity Thermogenesis (Neat) In Adults, Jiangqi Tang
Wayne State University Theses
Increased sedentary behavior, just like reduced physical activity, has been shown to increase the risk of obesity and chronic diseases. This is mostly due to increased time spent sitting at the office desk. There is limited research studying how to decrease such risk in office workers (OW). This study was to investigate a portable device "Desk Jockey" (DJ) on increasing NEAT and reducing sedentary behavior in a simulated office environment. Participants whose daily work requiring long sitting hours were recruited (mean sitting hours/day: 8.6 ± 3 hr, mean age: 25 ± 7 yr, 54% male, 15% obese). Metabolic rates (METs), …
Is Propranolol Administration Following A Traumatic Event Effective In Reducing Symptoms Of Post-Traumatic Stress Disorder?, Timothy J. Goulet
Is Propranolol Administration Following A Traumatic Event Effective In Reducing Symptoms Of Post-Traumatic Stress Disorder?, Timothy J. Goulet
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective EBM review is to determine whether or not propranolol administration following a traumatic event is effective in reducing symptoms of post-traumatic stress disorder (PTSD).
STUDY DESIGN: Review of three English language randomized, double-blind, placebo-controlled clinical trials published in 2002, 2007, and 2010.
DATA SOURCES: Three randomized, double-blind, placebo-controlled clinical trials found using PubMed and Cochrane Library databases.
OUTCOMES MEASURED: The incidence of PTSD symptoms was measured in patients following traumatic events after the administration of propranolol. This was done using The Screening Tool for Early Predictors of PTSD, the Clinician …
Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel
Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel
The Science Journal of the Lander College of Arts and Sciences
Women who have a history of eating disorders, specifically anorexia nervosa, are more prone to suffer from infertility. There are several hormones which are the driving force in this system and are therefore responsible for this. Fortunately, there are treatments which can help women with a history of eating disorders to reproduce. Using information found on Pubmed and Touro College’s database, this paper will discuss why the body cannot reproduce when it is lacking proper nutrition, as well as the various dynamics in the human reproductive system which are compromised when the body is not properly nourished.
Caffeine And Human Perception Of Time, Trevor Fry
Caffeine And Human Perception Of Time, Trevor Fry
EWU Masters Thesis Collection
The purpose of this study was to investigate the effect of caffeine on several components of time perception in an attention-demanding task. Review of the current literature shows that the rhythm of the brain's internal clock, controlled by the suprachiasmatic nucleus (SCN), which is believed to mediate the perception of short durations, is sensitive to a variety of stimuli including stimulants. This study expands on previous research on the effect of caffeine on prospective time estimation by having participants estimate multiple short durations while completing a cognitively complex time estimation task involving math. The study included a moderate dose caffeine …
Dopamine And Glutamate Dysfunction In A Rodent Model Of Attention-Deficit/Hyperactivity Disorder: Implications For Future Neuropharmacology, Erin M. Miller
Dopamine And Glutamate Dysfunction In A Rodent Model Of Attention-Deficit/Hyperactivity Disorder: Implications For Future Neuropharmacology, Erin M. Miller
Theses and Dissertations--Neuroscience
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders of childhood. It is theorized to be caused by catecholamine dysfunction in the striatum (Str) and frontal cortex (FC). The spontaneously hypertensive rat (SHR) has been used as a model for ADHD because of its attention deficits, impulsiveness, and hyperactivity. Prior studies of dopamine (DA) in the Str and FC have revealed conflicting results in the SHR compared to control, indicative of a need for a better understanding of DA dynamics in this model. In addition to the DA hypothesis, studies have begun implicating glutamate in the etiology of ADHD. …
Exercise Behavior Patterns In Emerging Adulthood: An Exploration Of Predictor Variables From Self-Determination Theory And Transtheoretical Model, Chad R. Johnson
Exercise Behavior Patterns In Emerging Adulthood: An Exploration Of Predictor Variables From Self-Determination Theory And Transtheoretical Model, Chad R. Johnson
College of Graduate Studies: Theses & Dissertations
During the transition from childhood to adulthood, young people establish patterns of behavior and make lifestyle choices that affect both their current and future health (NCHS, 2010). Emerging adulthood – a new conception of development for the period from the late teens through the twenties – focuses on individuals ages 18-25 who did not have a child, own a home, or have sufficient income to be fully independent (Arnett, 2000). Very little is known about social influence, motivational mediators, and motivation on exercise behavior within this developmental period. Therefore, the purpose of this study was to determine the influence of …
Inhibitory Control Deficits And Post-Traumatic Stress Disorder: Evidence From Eye Blink Rate, Mikael Rubin
Inhibitory Control Deficits And Post-Traumatic Stress Disorder: Evidence From Eye Blink Rate, Mikael Rubin
Dissertations and Theses
No abstract provided.
Day Occupation Is Associated With Psychopathology For Adolescents And Young Adults With Down Syndrome, Kitty-Rose R. Foley, Peter Jacoby, Stewart Einfeld, Sonya Girdler, Jenny Bourke, Vivienne Riches, Helen Leonard
Day Occupation Is Associated With Psychopathology For Adolescents And Young Adults With Down Syndrome, Kitty-Rose R. Foley, Peter Jacoby, Stewart Einfeld, Sonya Girdler, Jenny Bourke, Vivienne Riches, Helen Leonard
Research outputs 2014 to 2021
Background: Young adults with Down syndrome experience increased rates of emotional and behavioural problems compared with the general population. Most adolescents with Down syndrome living in Western Australia participate in sheltered employment as their main day occupation. Relationship between day occupation and changes in behaviour has not been examined. Therefore, the aim of this research was to explore any relationship between post school day occupations and changes in the young person's behaviour.Methods: The Down syndrome Needs Opinion Wishes database was used for case ascertainment of young adults aged 15 to 32 years with Down syndrome. Families of 118 young people …
Psychophysiological Research Of Borderline Personality Disorder: Review And Implications For Biosocial Theory, Tara Cavazzi, Rodrigo Becerra
Psychophysiological Research Of Borderline Personality Disorder: Review And Implications For Biosocial Theory, Tara Cavazzi, Rodrigo Becerra
Research outputs 2014 to 2021
According to the Biosocial theory, Borderline Personality Disorder (BPD) is developed by a biological predisposition to hyperarousal and hyperreactivity combined with an invalidating environment. Although widely supported by subjective measures, the impaired insight present in BPD may skew results, and thus psychophysiological measures have been suggested as an alternative method of examining possible biological differences in BPD. The current review aimed to critically assess psychophysiological research of BPD by electronic searching of relevant databases, with 22 articles meeting inclusion criteria. Results showed that in contrast to the hyperarousal proposed in the Biosocial theory, BPD was associated with hypoarousal and hyporeactivity …
Altering Endoplasmic Reticulum Stress In A Model Of Blast-Induced Traumatic Brain Injury Controls Cellular Fate And Ameliorates Neuropsychiatric Symptoms, Aric Flint Logsdon, Ryan Coddington Turner, Brandon Peter Lucke-Wold, Matthew James Robson, Zachary James Naser, Kelly Elizabeth Smith, Rae Reiko Matsumoto
Altering Endoplasmic Reticulum Stress In A Model Of Blast-Induced Traumatic Brain Injury Controls Cellular Fate And Ameliorates Neuropsychiatric Symptoms, Aric Flint Logsdon, Ryan Coddington Turner, Brandon Peter Lucke-Wold, Matthew James Robson, Zachary James Naser, Kelly Elizabeth Smith, Rae Reiko Matsumoto
Faculty Publications & Research of the TUC College of Pharmacy
Neuronal injury following blast-induced traumatic brain injury (bTBI) increases the risk for neuropsychiatric disorders, yet the pathophysiology remains poorly understood. Blood-brain-barrier (BBB) disruption, endoplasmic reticulum (ER) stress, and apoptosis have all been implicated in bTBI. Microvessel compromise is a primary effect of bTBI and is postulated to cause subcellular secondary effects such as ER stress. What remains unclear is how these secondary effects progress to personality disorders in humans exposed to head trauma. To investigate this we exposed male rats to a clinically relevant bTBI model we have recently developed. The study examined initial BBB disruption using Evan’s blue (EB), …
Idiots Savants, Retarded Savants, Talented Aments, Mono-Savants, Autistic Savants, Just Plain Savants, People With Savant Syndrome, And Autistic People Who Are Good At Things: A View From Disability Studies, Joseph N. Straus
Publications and Research
People identified as idiot savants have long comprised an identifiable group (a high level of skill in the context of perceived mental deficiency) whose story has mostly been told by psychiatrists and psychologists within a medicalized model of disability that assumes deficiency and seeks remediation and normalization. More recently, people identified as savants have become common figures of literary and cinematic representation. Both of these narrative frames have enfreaked them as alien Others, whose gifts and disabilities place them outside the normal run of human intelligence and creativity. With a focus on music, this article tries to see through these …
Coping Responses And Mental Health Symptoms In Incarcerated Juvenile Males, Jennifer Renae Newhard
Coping Responses And Mental Health Symptoms In Incarcerated Juvenile Males, Jennifer Renae Newhard
Antioch University Dissertations & Theses
Coping responses develop throughout the lifespan of an individual. Unfortunately for some, difficult life circumstances may lead to the use of maladaptive forms of coping. This study investigated coping responses amongst male incarcerated juvenile offenders and examined which specific mental health symptoms may occur with specific coping responses. The goal of this study was to determine whether male incarcerated juvenile offenders utilize avoidant coping responses over approach coping responses. Also, this study investigated whether specific mental health symptoms, such as depression, anxiety, anger, and disruptive behaviors, were more prevalent amongst those who utilize avoidant coping responses. De-identified, archival data for …
Depression In Children And Adolescents: The Role Of School Professionals, Emily Dawn Hoerman
Depression In Children And Adolescents: The Role Of School Professionals, Emily Dawn Hoerman
Dissertations and Theses @ UNI
Depression in children and adolescents is a significant issue for schools. Research has indicated that most students who see mental health professionals do so within the school setting, indicating a need for effective school-based programs to address mental health issues in the schools. The symptoms of depression and short and long term effects are reviewed. The need for, and necessary components of, a comprehensive mental health system in the school setting is discussed.
Optimism And Planning For Future Care Needs Among Older Adults, Silvia Sörensen, Jameson K. Hirsch, Jeffrey M. Lyness
Optimism And Planning For Future Care Needs Among Older Adults, Silvia Sörensen, Jameson K. Hirsch, Jeffrey M. Lyness
ETSU Faculty Works
Aging is associated with an increase in need for assistance. Preparation for future care (PFC) is related to improved coping ability as well as better mental and physical health outcomes among older adults. We examined the association of optimism with components of PFC among older adults. We also explored race differences in the relationship between optimism and PFC. In Study 1, multiple regression showed that optimism was positively related to concrete planning. In Study 2, optimism was related to gathering information. An exploratory analysis combining the samples yielded a race interaction: For Whites higher optimism, but for Blacks lower optimism …
Adult Response To Olanzapine Or Clozapine Treatment Is Altered By Adolescent Antipsychotic Exposure: A Preclinical Test In The Phencyclidine Hyperlocomotion Model, Qing Shu, Gang Hu, Ming Li
Adult Response To Olanzapine Or Clozapine Treatment Is Altered By Adolescent Antipsychotic Exposure: A Preclinical Test In The Phencyclidine Hyperlocomotion Model, Qing Shu, Gang Hu, Ming Li
Department of Psychology: Faculty Publications
This study examined how repeated olanzapine (OLZ) or clozapine (CLZ) treatment in adolescence alters sensitivity to the same drug in adulthood in the phencyclidine (PCP) hyperlocomotion model. Male adolescent Sprague-Dawley rats (postnatal day (P) 44–48) were first treated with OLZ (1.0 or 2.0 mg/kg, subcutaneously (sc)) or CLZ (10.0 or 20.0 mg/kg, sc) and tested in the PCP (3.2 mg/kg, sc)-induced hyperlocomotion model for five consecutive days. Then a challenge test with OLZ (0.5 mg/kg) or CLZ (5.0 mg/kg) was administered either during adolescence (~P 51) or after the rats matured into adults (~P 76 and 91). During adolescence, repeated …