Psychiatry and Psychology Commons^™

A Cocktail Nanovaccine Targeting Key Entry Glycoproteins Elicits High Neutralizing Antibody Levels Against Ebv Infection, Ling Zhong, Wanlin Zhang, Hong Liu, Xinyu Zhang, Zeyu Yang, Zhenfu Wen, Ling Chen, Haolin Chen, Yanran Luo, Yanhong Chen, Qisheng Feng, Mu-Sheng Zeng, Qinjian Zhao, Lixin Liu, Claude Krummenacher, Yi-Xin Zeng, Yongming Chen, Miao Xu, Xiao Zhang

Faculty, Staff and Student Publications

Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely associated with various malignancies. Considering the complex life cycle of EBV, developing vaccines targeting key entry glycoproteins to elicit robust and durable adaptive immune responses may provide better protection. EBV gHgL-, gB- and gp42-specific antibodies in healthy EBV carriers contributed to sera neutralizing abilities in vitro, indicating that they are potential antigen candidates. To enhance the immunogenicity of these antigens, we formulate three nanovaccines by co-delivering molecular adjuvants (CpG and MPLA) and antigens (gHgL, gB or gp42). These nanovaccines induce robust humoral and cellular responses through efficient …

Cues And Identity: Assessing Substance Use Cues, Life Experience, And Context, Katelynn Carlsen

USF Tampa Graduate Theses and Dissertations

This project employs Ecological Momentary Assessment (EMA) methods alongside semi-structured interviews to examine substance use cues, or “triggers”, in the everyday context. This includes repeated assessment of participants’ behaviors and thoughts over time. EMA allows researchers to sample phenomena the moment they occur within the context. These methods are most used in psychology and clinical science. Current research on substance use relies on lab-based assessments to understand cues and their relationship to consumption (Carter and Tiffany 1999, Conklin and Tiffany 2003, Witteman et al. 2015). This analysis uses data collected by the Cues in the Everyday (CITED) Team. The CITED …

Predictors Of Help Seeking Among Asian Americans With Chronic Pain, Cory Duffield

Clinical Psychology Dissertations

Purpose: Chronic pain can contribute to both physical discomfort and psychological distress. Psychological distress may sometimes increase the odds of seeking help for pain. On the other hand, factors such as attitudes towards receiving help and the need to present oneself as perfect may constitute barriers to seeking help for pain. However, relatively little research has examined such processes in Asian American individuals experiencing chronic pain.

Aim: This study aimed to better understand, in Asian Americans that reported chronic pain, the relationships among distress, help-seeking attitudes, perfectionistic self-presentation (PSP) in predicting help-seeking behaviors. It tested whether higher distress would predict …

Mean Affect Moderates The Association Between Affect Variability And Mental Health, Brooke N. Jenkins, Lydia Q. Ong, Anthony D. Ong, Hee Youn (Helen) Lee, Julia K. Boehm

Psychology Faculty Articles and Research

Increasing evidence suggests that within-person variation in affect is a dimension distinct from mean levels along which individuals can be characterized. This study investigated affect variability’s association with concurrent and longitudinal mental health and how mean affect levels moderate these associations. The mental health outcomes of depression, panic disorder, self-rated mental health, and mental health professional visits from the second and third waves of the Midlife in the United States Study were used for cross-sectional (n = 1,676) and longitudinal outcomes (n = 1,271), respectively. These participants took part in the National Study of Daily Experiences (NSDE II), …

History Of Suicidal Behavior And Clozapine Prescribing Among People With Schizophrenia In China: A Cohort Study, Yi Yin, Chen Lin, Lijing Wei, Jinghui Tong, Junchao Huang, Baopeng Tian, Shuping Tan, Zhiren Wang, Fude Yang, Yongsheng Tong, Song Chen, L Elliot Hong, Yunlong Tan

Faculty, Staff and Student Publications

BACKGROUND: Clozapine is an off-label drug used in most countries to prevent suicide in individuals with schizophrenia. However, few studies have reported real-world prescription practices. This study aimed to explore the association between a history of suicidal behavior and clozapine prescribing during eight weeks of hospitalization for individuals with early-stage schizophrenia.

METHODS: This observational cohort study used routine health data collected from a mental health hospital in Beijing, China. The study included 1057 inpatients who had schizophrenia onset within 3 years. History of suicidal behavior was coded from reviewing medical notes according to the Columbia Suicide Severity Rating Scale. Information …

Family Fragments: Pressure And Proximity In First-Episode Psychosis, Cassandra B. Seltman

Dissertations, Theses, and Capstone Projects

This study explores the value of assuming a position that decenters the identified patient in families with a member with schizophrenia. Instead, a systemic view of the family is taken, as subject to pressures from without and within, and utilizing observable processes for the management and discharge of tension. It attempts the difficult balance of thinking dynamically without sacrificing scientific rigor, considering the social without discounting the biological, and exploring the functionality of the family without collapsing into blame, reductive cause-and-effect thinking, and the search to prioritize one true origin.

When treating family members as discrete units around an identified …

Accessible Real-Time Eye-Gaze Tracking For Neurocognitive Health Assessments, A Multimodal Web-Based Approach, Daniel C. Tisdale

Master's Theses

We introduce a novel integration of real-time, predictive eye-gaze tracking models into a multimodal dialogue system tailored for remote health assessments. This system is designed to be highly accessible requiring only a conventional webcam for video input along with minimal cursor interaction and utilizes engaging gaze-based tasks that can be performed directly in a web browser. We have crafted dynamic subsystems that capture high-quality data efficiently and maintain quality through instances of user attrition and incomplete calls. Additionally, these subsystems are designed with the foresight to allow for future re-analysis using improved predictive models, as well as enable the creation …

Determining Factors For Improved Uptake Of Harm Reduction Services In The United States: A Study Of Inclusive, Culturally Sensitive Messaging, Lauretta Ekanem Omale

Dissertations

Harm reduction refers to public health policies and programs aimed at decreasing the adverse consequences associated with drug use. While harm reduction services (e.g., syringe exchange programs) can mitigate health risks, marginalized groups face barriers to service access and utilization, partially due to ineffective messaging approaches that fail to align with cultural values and experiences. A one-size-fits-all approach to messaging can negatively impact service utilization, health outcomes, and health disparities. Ineffective communication can lead to poor adherence to treatment, poorer health outcomes, and increased adverse events.

Culturally insensitive communication contributes to stigma, mistrust, and lack of perceived relevance, discouraging service …

Dietary Probiotic Supplement Attenuates Methamphetamine-Induced Conditioned Place Preference In Female Sprague-Dawley Rats, Kristen Powell

Masters Theses

Substance use disorders (SUD) represent a global public health crisis with limited effective treatment options. Recent findings implicate the gut microbiome and gut/brain axis in the pathophysiology of SUDs. Several preclinical studies have established that psychostimulants alter gut microbiome composition, but no published studies have assessed behavioral effects of dietary probiotic supplements on drug-induced behavioral changes. This study utilized rodent conditioned place preference (CPP) as a behavioral index of conditioned drug reward to determine if a dietary probiotic supplement alters the behavioral effects of (+)-methamphetamine (METH). Fifty-four adult female Sprague-Dawley rats were randomly assigned to receive either a standard rodent …

Effects Of A Cb1 Receptor Antagonist On Anxiety In Adult Rats Exposed To Thc During Development, Jennifer Aguilera-Fonseca, Karla Colley, Atoria Hamm, Eddie Galarza, Joe Morse, Rachel Ntor, Destiny Pichardo, Vincent P. Markowski

McNair Scholars Program

No abstract provided.

Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi

Publications and Research

Background The Pandemic Anxiety Inventory (PAI) was developed in the context of the COVID-19 pandemic. Its content allows it to assess anxiety in connection to any pandemic. Previous research has demonstrated the instrument’s reliability and validity. An important question for clinicians and researchers, however, remains open: Does the PAI have similar meaning for members of different demographic groups? The finding of measurement invariance would allow clinicians and researchers to comparatively assess pandemic-related anxiety across demographic groups, including favored and disfavored groups.

Methods We conducted a multi-group confirmatory factor analysis to assess the measurement invariance of the PAI using data obtained …

Individual Longitudinal Changes In Dna-Methylome Identify Signatures Of Early-Life Adversity And Correlate With Later Outcome, Annabel K. Short, Ryan Weber, Noriko Kamei, Christina Wilcox Thai, Hina Arora, Ali Mortazavi, Hal S. Stern, Laura M. Glynn, Tallie Z. Baram

Psychology Faculty Articles and Research

Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas the enduring impact of ELA on cognitive and emotional health is established, there are no tools to predict vulnerability to ELA consequences in an individual child. Epigenetic markers including peripheral-cell DNA-methylation profiles may encode ELA and provide predictive outcome markers, yet the interindividual variance of the human genome and rapid changes in DNA methylation in childhood pose significant challenges. Hoping to mitigate these challenges we examined the relation of several ELA dimensions to DNA methylation changes and outcome using a within-subject longitudinal design and a high methylation-change threshold. …

Resonant Perceptions: Exploring Autistic Aesthetics Through Embodied Cognition, James Hutson, Piper Hutson

Ought: The Journal of Autistic Culture

This study investigates the nuanced realm of aesthetic preferences among individuals with Autism Spectrum Condition (ASC) compared to neurotypical individuals, addressing a significant gap in understanding the diverse perceptual experiences within the neurodiverse community. The impetus for this study stems from the growing recognition of neurodiversity and the need to appreciate how individuals with ASC uniquely experience and interpret their environment, particularly in the context of aesthetics. Employing a dual-method approach, the research integrates data from comprehensive surveys and in-depth interviews to construct a comparative analysis of aesthetic preferences and experiences. Participants encompassed a broad demographic spectrum, ensuring a diverse …

A Microcosting Approach For Planning And Implementing Community-Based Mental Health Prevention Program: What Does It Cost?, Sharmily Roy, Henry Shelton Brown, Lisa Sanger Blinn, Sarah Carter Narendorf, Jane E Hamilton

Faculty, Staff and Student Publications

BACKGROUND: Estimating program costs when planning community-based mental health programs can be burdensome. Our aim was to retrospectively document the cost for the first year of planning and implementing Healthy Minds Healthy Communities (HMHC), a mental health promotion and prevention multi-level intervention initiative. This Program is among the first to use the Community Initiated Care (CIC) model in the US and is aimed at building community resilience and the capacity for communities to provide mental health support, particularly among those disproportionately impacted by COVID-19. Our objective is to share our methods for costing a program targeting 10 zip codes that …

Colorful Conversations: Enhancing Communication In Nonspeaking Toddlers Through Art Therapy, Joy Wu

Expressive Therapies Capstone Theses

The purpose of this study was to learn how art therapy helps non-speaking children ages two years old build up their communication with others. Although there are not many early publications on the benefit of art therapy to children ages two, the existing research suggests that art therapy can aid those children in speaking based on the experience of art making. During the art creation process, engaging with art materials and their potential power can enable the expression and conveyance of emotions as art serves as containment. Therefore, art therapy can assist nonspeaking toddlers to begin communicating verbally. This writer …

Regulation Through Rhythm: A Literature Review On Dance/Movement Therapy Approaches To Facilitating Nervous System Regulation, Elizabeth Barbera

Expressive Therapies Capstone Theses

Abstract

The mental health field has started to pay attention to how trauma plays into a person’s overall mental and physical well-being. Because of this more research has shown the connection between mind and body. Yet the clinical implications and literature on theories of how to treat trauma and trauma related disorders do not always connect. This review of literature seeks to analyze the literature on Porges’, Polyvagal Theory and Amighi’s, Kestenberg Movement Profiles. An investigation of the current literature makes a connection between the phylogenetic order of both the nervous system and developmental movement. Considerations of how trauma, in …

Embodied Co-Regulation: A Neuroregulatory-Informed Dance/Movement Therapy Transition Intervention Method For Arousal Regulation For Adolescents In A Partial Hospitalization Program, Anamaria Guzman

Expressive Therapies Capstone Theses

This thesis introduces a novel Dance/Movement Therapy (DMT) approach, focusing on nervous system arousal regulation during transitions between therapy groups. The core of the method involves a brief 5-minute exercise designed to modulate arousal levels, encompassing alertness and energy, aiming to establish a baseline homeostasis. Rooted in Polyvagal Theory and Developmental Neurobiology, the approach assumes the co-regulation of nervous systems within a group therapeutic setting. Two primary outcomes are self-assessed: 1) somatic experiences documented through narratives and 2) nervous system biodata measured using the Flowtime headband monitoring of brainwaves, heart rate, and other biomarkers. Results indicated that all six sessions …

Utilizing Dance/Movement Therapy For Children With Attention-Deficit/Hyperactivity Disorder: Development Of A Method, Jayda Pearson

Expressive Therapies Capstone Theses

While there is limited research on the use of dance/movement therapy (DMT) with attention-deficit/hyperactivity disorder. This thesis introduces an intervention focused on utilizing (DMT) to assist children with ADHD in self-regulation during periods of dysregulation associated with the disorder. The research is backed by literature reviews covering various topics related to ADHD symptoms such as dysregulation, impulsivity, and attention difficulties. Furthermore, the thesis delves into the background of dance/movement therapy and explores how DMT can be integrated with other modalities such as play therapy for a comprehensive therapeutic approach.

Utilizing Flow Arts Movement As An Expressive Arts Therapy Tool To Treat Trauma: A Literature Review And Autoethnography, Shannon Mcgrail

Expressive Therapies Capstone Theses

This expressive arts-based autoethnography research explores the effectiveness of using flow arts movement as a tool of expressive arts therapy to treat symptoms of trauma for individuals who experienced a traumatic event in their lifetime. While research on the use of flow arts movement to treat mental illness is in its early stage, much can be drawn from the literature on expressive arts therapy and dance/movement therapy research with a range of populations addressing trauma. Through exploration of trauma through neuroscience, mind, body, and integrated mindfulness through flow, this work aims to bring an understanding of using intermodal expressive arts …

Feldenkrais And Music Informed Listening: A Neurophenomenological Perspective On Autism, Arona Primalani

Expressive Therapies Capstone Theses

Phenomenologists identify the subjective body and its felt-senses as the basis for human development and consciousness, including mental health. Several mental health disorders, when viewed from a phenomenological perspective, share common symptomology related to varying extents of fractured selves, which in turn hinders dynamic interaction between individuals, their actions, and their relationships with their social and material worlds. Autism is one such condition. Hence, I created an intervention to investigate how listening, which foster subjective and intersubjective experiences, lies at the heart of somatic and arts-based interventions. This thesis, first, begins with a summary of the presenting symptoms observed in …

Re-Member Selfhood A Drama Therapy Intervention, Option 1, Angelique Beauchêne

Expressive Therapies Capstone Theses

Re-member Selfhood is a specific trauma-informed, drama therapy, intervention designed to meet the needs of adults with exposure to trauma and traumatic stress, who have pertinent adverse childhood experience scores and/or experience persistent trauma cycles over the lifespan concurrent with somatization. The aim of this thesis was to introduce an intervention which could function as indirect exposure and assist in the integration process taking the whole being of trauma sufferers into account, including body, mind, and soul. Additionally, the hope of this intervention is to decrease perceived physical pain, assist in the integration of the rejected aspect of self, and …

Exploring The Role Of Pain On Physical Activity Among Youth With Acute Lymphoblastic Leukemia Using The Biopsychosocial Model, Anna E. Van Asselt, Renee Gilbert, Meghan Tokala, Jacee Weber, Meredith L. Dreyer Gillette, Robert C. Gibler, Carolyn R. Bates, Keith August

Research Days

The Role of Pain on Physical Activity in Pediatric ALL

Keywords: Biopsychosocial model, pediatric Acute Lymphoblastic Leukemia, pain, physical activity

Introduction: Engaging in physical activity (PA) during cancer treatment benefits a child’s physical and mental well-being (McLaughlin et al., 2021). However, engaging in PA may be challenging due to treatment and disease-related pain (Uhl et al., 2020). Pediatric cancer research has primarily focused on management of procedural and chronic pain, with fewer studies examining how pain may interfere with PA during treatment (Clews et al., 2022). The current study qualitatively investigated the impact of pain on PA using a …

Teacher Voices: Stress And Coping Mechanisms Among The Teaching Profession, Jasmine Suttles

Education | Master's Theses

Stress is a natural response that occurs in our body when we feel overwhelmed, and it can manifest in both positive and negative instances. The teaching profession is not exempt from this phenomenon, as it is unique in that educators have multiple roles to play and have to manage and interact with many students simultaneously. Teachers have been described as "exasperated by heavy loads of emotional labor in the classroom" (Ferguson et al., 2022). This "heavy load" can place the teaching profession at risk of stress and burnout if self-care is not addressed or mental health resources are not offered. …

The Relationship Between Autistic Traits, Autistic Camouflaging, And Adults’ Representations Of Abstract And Social Concepts, Henry Tomiser, Katja Wiemer Dr.

Honors Capstones

Concrete concepts (e.g., BUTTON) can be experienced directly by the senses, whereas abstract concepts (e.g., FRIENDSHIP) cannot. Additionally, the mind may represent abstract concepts using more introspective, social, and emotional information than concrete concepts. Social difficulties are one defining feature of autism, and autistic individuals may use social camouflaging to hide these difficulties, but the precise nature of social processing in autism is not known. This study aims to explore possible links between autistic traits, autistic camouflaging, and mental representations of concepts. Participants gave open-ended definitions for concepts varying in concreteness and social content via an online survey. Responses were …

Trends In Substance Use And Mental Health Among Adolescents In Georgia, 2002-2022, Saumya S. Palipudi, Bangaru Talli Palipudi, Murty Komanduri

Georgia Public Health Association Annual Meeting & Conference

Background: While substance use and absence of mental health disorders among youth in the United States (US) have declined over the past two decades, post COVID-19 pandemic, these conditions have increased significantly with notable disparities, and witnessed a crisis in public health. In 2022, 24.7% or 6.1 million adolescents aged 12 to 17 in the US had either Major Depressive Episodes (MDE) or Substance Use Disorder (SUD) and 3.7 percent had both in the prior year². Increased stress, lack of peer connections, parental abuse, and poor mental health conditions were attributed to this increase in substance use^{3-7 …}

Emotion Regulation Strategies And Perceived Emotional Intelligence: The Effect Of Age., Iwanna Sepiadou

Adultspan Journal

The aim of this study was to investigate the relationship between perceived emotional intelligence and the reported use of cognitive reappraisal and expressive suppression. We also investigated the possible effects of age on the aforementioned variables. The total sample consisted of 379 people (158 men, 220 women, 1 unreported). Across participants, 273 were young (20-39 years old) and 106 were middle-aged (40-65 years old). We found statistically significant positive correlations between the dimensions of perceived emotional intelligence and the reported use of cognitive reappraisal and negative primarily correlations between the dimensions of perceived emotional intelligence and the reported use of …

Expressive Therapies And Resiliency – Resistance In Mental Health: A Literature Review, Gabrielle Lopez

Expressive Therapies Capstone Theses

This review evaluates the current literature on psychological resistance amongst human service professionals experiencing burnout and the effect of Expressive Arts interventions on resiliency. Concepts include identifying the main symptoms, risk factors, causes, and treatments for burnout in education faculty, medical staff, and clinicians. Qualitative, quantitative, and meta-analysis studies are included to identify the most prevalent intervention frameworks for reducing stress including Arts-Based and Mindfulness-compassion based techniques. The effectiveness of Arts-based tools on strengthening identity, self-esteem, emotional regulation, and meaning-making in combating burnout is presented. Based on analysis of the literature, the author proposes a three-step intervention framework for utilizing …

An Actuarial Prediction Of Adhd Using Neuropsychological Data, Kimberlyn Williams

Poster Presentations

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most common psychiatric diagnosis in children and a frequent psychiatric diagnosis in adults. ADHD is a clinical diagnosis based on self-reported symptoms which makes accurate diagnosis challenging. Actuarial prediction has been demonstrated to be more accurate than clinical judgment. The current study explored an actuarial approach to predicting ADHD based on a comprehensive battery of neuropsychological tests. This project utilized test data from Meyers Neuropsychological Battery (MNB) to develop a logistic regression model to accurately predict diagnosed ADHD cases (n=65) from normal functioning cases (n=79) with a history of Mild Traumatic Brain Injury (mTBI). Binary …

Evaluating The Effectiveness Of A School-Based Cognitive Behavioral Youth Depression Prevention Program In Improving Life Satisfaction, Roshani Patel, Steven M. Brunwasser, Alissa Hochman

Rowan-Virtua Research Day

Depression is the leading cause of disability worldwide, known as the global burden of disease. Incident cases from 1990 to 2017 have increased by 49.86%. Additionally, rates have been seen to dramatically rise in adolescents aged 18-25 (17%) compared to rates in individuals aged 10-14 (1.1%). This makes it beneficial to have prevention programs for middle school aged children. The Penn Resiliency Program (PRP) is a youth depression prevention program focused on cultivating healthy thinking styles and behavioral coping skills. In our study, we used archival data from a randomized control trial of PRP to evaluate whether the program led …

Incorporating Ai Tools To Enhance Information Literacy And Critical Thinking In First Year Medical Students, James Martin Ii, Mercedes Byrd

Rowan-Virtua Research Day

This study aims to evaluate the impact of an educational intervention incorporating medical databases, search engines, and generative artificial intelligence (GAI) tools on the critical thinking skills and confidence of first-year medical students at Rowan-Virtua School of Osteopathic Medicine (SOM). Approximately 125 students participating in a three-week pre-matriculation program will be subjects of the study. The intervention will consist of a curriculum focused on developing research questions, using search tools and GAI, evaluating sources, and writing a research paper. Pre- and post-tests, including a CARS assessment and a perceived knowledge and abilities questionnaire, will be administered to measure changes in …