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Articles 1501 - 1530 of 2885
Full-Text Articles in Psychiatry and Psychology
Mouse Performance On A Novel Touchscreen Continuous Performance Task Is Dependent On Signaling In The Prelimbic Cortex, Tyler D. Dexter, Daniel Palmer, Amy C. Reichelt, Anita Taksokhan, Lisa M. Saksida, Tim J. Bussey
Mouse Performance On A Novel Touchscreen Continuous Performance Task Is Dependent On Signaling In The Prelimbic Cortex, Tyler D. Dexter, Daniel Palmer, Amy C. Reichelt, Anita Taksokhan, Lisa M. Saksida, Tim J. Bussey
Western Research Forum
Attention is the cognitive processing that facilitates the ability to target and attend to relevant environmental stimuli, while filtering out irrelevant or distracting stimuli. Control over selective attention is theorized to be dependent on organized neural communication that stems from the medial prefrontal cortex (mPFC). To evaluate selective and sustained attention, mice were trained on the novel touchscreen rodent continuous performance task (rCPT), a task designed to emulate the human CPT. In the rodent version, images are continuously presented on a touchscreen, where mice have been trained to selectively respond to one image type while suppressing responses to all others. …
Partnering With A Different Faith: Muslim American Women’S Experiences, Beyza Sinan
Partnering With A Different Faith: Muslim American Women’S Experiences, Beyza Sinan
Seton Hall University Dissertations and Theses (ETDs)
The events of September 11, 2001 critically impacted the identity of Muslim Americans in the United States and spurred attention to their experiences within the psychological literature. Prior literature has rarely explored these individuals’ within-group differences, defined Muslim American identity as bicultural, or explored experiences of being in a romantic relationship. This study was intended to address the gaps in the literature by focusing on the bicultural identity and the experience of interfaith relationships among Muslim American women. The following research questions guided this study: 1) How do Muslim American women experience their romantic relationship with a non-Muslim partner? 2) …
An Integration-To-Bound Model Of Decision-Making That Accounts For The Spectral Properties Of Neural Data, Ramón Guevara Erra, Marco Arbotto, Aaron Schurger
An Integration-To-Bound Model Of Decision-Making That Accounts For The Spectral Properties Of Neural Data, Ramón Guevara Erra, Marco Arbotto, Aaron Schurger
Psychology Faculty Articles and Research
Integration-to-bound models are among the most widely used models of perceptual decision-making due to their simplicity and power in accounting for behavioral and neurophysiological data. They involve temporal integration over an input signal (“evidence”) plus Gaussian white noise. However, brain data shows that noise in the brain is long-term correlated, with a spectral density of the form 1/fα (with typically 1 < α < 2), also known as pink noise or ‘1/f’ noise. Surprisingly, the adequacy of the spectral properties of drift-diffusion models to electrophysiological data has received little attention in the literature. Here we propose a model of accumulation of evidence for decision-making that takes into consideration the spectral properties of brain signals. We develop a generalization of the leaky stochastic accumulator model using a Langevin equation whose non-linear noise term allows for varying levels of autocorrelation in the time course of the decision variable. We derive this equation directly from magnetoencephalographic data recorded while subjects performed a spontaneous movement initiation task. We then propose a nonlinear model of accumulation of evidence that accounts for the ‘1/f’ spectral properties of brain signals, and the observed variability in the power spectral properties of brain signals. Furthermore, our model outperforms the standard drift-diffusion model at approximating the empirical waiting time distribution.
Get Engaged: Results Of Ncpg 2018 National Survey Of Gambling Attitudes & Experiences, Keith Whyte, Don Feeney
Get Engaged: Results Of Ncpg 2018 National Survey Of Gambling Attitudes & Experiences, Keith Whyte, Don Feeney
International Conference on Gambling & Risk Taking
The National Survey of Gambling Attitudes and Gambling Experiences (NGAGE) is the largest published survey of gambling participation and problems in the US. This unprecedented look into how Americans gamble, what they gamble, how they think about it in every state. Includes a special focus on sports gambling. Presenters will review the findings and implications for everyone involved in gambling issues.
Human Learning, Memory, And Student Development, Alan R. Erickson
Human Learning, Memory, And Student Development, Alan R. Erickson
Contemporary Issues in Educational Leadership
My educational interests have largely been informed by my career in the sciences and medicine. My professional education has been both formative and transformative, opening doors to the joy of learning and a realization in the importance of memory. As an educator, clinician, and student, I have been greatly impacted by issues of curricular design, curricular development, learning and memory. My current responsibilities in student affairs also have exposed me to the delicate balance between student development, curricular design, learning and memory. Patton, Renn, Guido, and Quaye (2016) noted the importance of educators being able to use different literature sources …
Promoting Resilience In Economically Disadvantaged Adolescents Through School-Based Expressive Arts Groups, Bailey Knox
Promoting Resilience In Economically Disadvantaged Adolescents Through School-Based Expressive Arts Groups, Bailey Knox
Expressive Therapies Capstone Theses
Since 2013, the majority of students served by the public school system in the United States have been considered “low-income” by the federal government. The stressors associated with low socioeconomic status significantly increase risk for social, emotional and behavioral challenges at all age levels, but can be particularly damaging to adolescents coping with heightened stress levels related to the intense multi-dimensional changes that define this developmental period. As the correlation between economic disadvantage and negative socio-emotional and academic outcomes is increasingly evidenced, schools have begun to recognize their responsibility for providing preventative mental health care to high-risk students. Over the …
A Literature Review Of Nature-Based Expressive Arts Therapy For Bereaved Children, Wendy Dalton
A Literature Review Of Nature-Based Expressive Arts Therapy For Bereaved Children, Wendy Dalton
Expressive Therapies Capstone Theses
There is a need for increased visibility of child bereavement to expand research in and accessibility of developmentally appropriate supports, which views the child holistically and within their biopsychosocial context. Worden’s (1996) formative work with child bereavement resulting in the "tasks" of child bereavement was the first and most recent study of its scale and kind. This marked an affirming of grief as normative response to death and occurring throughout the developmental lifespan. This work also highlights the need for additional inquiry to expand and deepen understanding of child bereavement. A growing body of research suggests that ecotherapy and expressive …
Dance/Movement Therapy As A Tool To Improve Social Skills In Children And Adolescents With Autism Spectrum Disorder: A Literature Review, Holly Berlandy
Dance/Movement Therapy As A Tool To Improve Social Skills In Children And Adolescents With Autism Spectrum Disorder: A Literature Review, Holly Berlandy
Expressive Therapies Capstone Theses
Abstract
Autism spectrum disorder is a neurodevelopmental disorder diagnosed by the presence of social communication and interaction deficits present in their day to day. The deficits present in this disorder appear within the first three years of life and lead to problems with connecting and interacting with other individuals including their own family members. As a result, children and adolescents with Autism spectrum disorder often experience negative self-image and lack the proper skills to interact with others. Autism spectrum disorder is becoming more commonly diagnosed and yet there remains a gap in interventions and treatment due to the individualized appearance …
Moving Blind Spots: Cultural Bias In The Movement Repertoire Of Dance/Movement Therapists, Ebony Nichols
Moving Blind Spots: Cultural Bias In The Movement Repertoire Of Dance/Movement Therapists, Ebony Nichols
Expressive Therapies Capstone Theses
This thesis explores the need for cultural diversity in the field of dance/movement therapy and the impact of unconscious bias as it relates to cultural rhythmic patterns, movement styles, and music choices in therapeutic practice. This literature review examines the historical context that has contributed to the field of dance/movement therapy while outlining cultural competency and ethical considerations in practice as it relates to cultural and/or race identity. Common themes are summarized notating the effects of oppression, bias, and trauma on populations of statistically marginalized communities with specific emphases on African American cultural identity. With consideration toward action steps, culturally …
Breathing Life Into Life: A Literature Review Supporting Body-Based Interventions In The Treatment Of Trauma, Andrea Werbalowksy
Breathing Life Into Life: A Literature Review Supporting Body-Based Interventions In The Treatment Of Trauma, Andrea Werbalowksy
Expressive Therapies Capstone Theses
In the recent turn toward a more trauma-informed practice of mental health counseling, a glaring gap remains between the research validating that trauma is a somatic experience and the continued privileging of cognitive and behaviorist interventions commonly used to treat trauma. In an effort to explore this gap, this paper presents a literature review inquiry into the neurophysiological and overall life effects trauma can have on the people who experience it. The review further explores how Stephen Porges’s Polyvagal Theory elucidates the benefits of using body-based therapeutic interventions in the treatment of trauma. The inquiry investigates the wide gap between …
“There Was Something Magical About This Group”: Building Cohesion In A Psychiatric Hospital, Mariah L. Logan
“There Was Something Magical About This Group”: Building Cohesion In A Psychiatric Hospital, Mariah L. Logan
Expressive Therapies Capstone Theses
This capstone details the development and implementation of Hope Notes, an expressive arts therapy intervention used in a private psychiatric hospital setting. Hope Notes was carried out in the group setting with adolescent and adult clients in a partial-hospitalization or inpatient hospitalization with a range of diagnoses and symptoms including, but not limited to, depression, anxiety, bipolar disorder, schizophrenia, trauma disorders including post-traumatic stress, and obsessive-compulsive disorder with symptoms of delusions, hallucinations, suicidality and homicidally. Using expressive arts therapy the clients worked together to collaboratively discuss, create, design, and build an art piece intended to increase group cohesion and connection …
Expressive Mindfulness: A Trauma-Sensitive Expressive Arts Therapy Group Method, Meghan Daly
Expressive Mindfulness: A Trauma-Sensitive Expressive Arts Therapy Group Method, Meghan Daly
Expressive Therapies Capstone Theses
Mindfulness and expressive arts therapy are both supportive of directing attention in a manner that promotes integration and function of a person. In this paper, a trauma-sensitive method was created for use in a day treatment setting for adults with severe and persistent mental illness (SPMI). This method utilized expressive movement, visual art making with three different materials, and creative writing to encourage mindful, non-judgmental acceptance of the present moment; a sense of relaxation; and an overall increase in quality of life. During development of the method arts-based research informed the choice of materials, music, and structure of the group. …
School-Based Mental Health Screening: Improving Outcomes Through Interprofessional Communication And Collaboration, Tiffany Gishizky
School-Based Mental Health Screening: Improving Outcomes Through Interprofessional Communication And Collaboration, Tiffany Gishizky
Doctor of Nursing Practice (DNP) Projects
For the adolescent population, the immediate impact a mental health disorder has on academics,relationships, and even suicide risk cannot be understated. Access to mental health care in low socioeconomic communities for adolescents is fraught with barriers. These include lack of transportation, lack of insurance coverage, fear of stigma, and a fundamental lack of knowledge regarding available resources. It is therefore a two-fold problem that exists for those in the care and observation of these adolescents; underutilization of appropriate routine screening and navigation to access care. This project aimed to remediate both of these issues at a high school located in …
Watering Black Roots: Exploring Black Ecological Identity Development Within Nature-Based Expressive Arts Therapy, Stormy Saint-Val
Watering Black Roots: Exploring Black Ecological Identity Development Within Nature-Based Expressive Arts Therapy, Stormy Saint-Val
Expressive Therapies Capstone Theses
Nature-based expressive arts therapy promotes the holistic healing and recovery of individuals by interweaving the practices of ecopsychology, ecotherapy, and expressive arts therapy. These interventions have been proven to mediate ranges of symptomologies, such as anxiety disorders and PTSD. Research conducted by the U.S. National Park Services indicates that African- Americans are less likely to have a positive relationship to nature than all other racial groups. The amplification of this report without introspection of its context perpetuates racialized generalizations. This can limit a black individual’s ability to embrace their ecological identity and be receptive of nature-based expressive arts therapy interventions. …
Orthorexia Nervosa Among Collegiate Female Student-Athletes, Maryse Bard-Martel
Orthorexia Nervosa Among Collegiate Female Student-Athletes, Maryse Bard-Martel
Graduate Theses/Dissertations
Orthorexia nervosa (ON) is a specific style of disordered eating defined as an unhealthy obsession with eating healthy food, or going to extremes in the pursuit of a diet that is supposed to be good for you. The purpose of this study was to explore the prevalence of orthorexia nervosa tendencies in college female soccer players in the NCAA Division 1. Purposive sampling was used, and participants were current student-athletes from the Missouri State women’s soccer team (n=18). Survey research was utilized to assess athletes’ attitudes and behaviors related to various aspects of diet and training, and the control it …
Efficacy Of Integrated Mental Health Care With Dual Diagnosis Patients And Their Utilization Of Psychiatric Emergency Services, Denton Scott
Efficacy Of Integrated Mental Health Care With Dual Diagnosis Patients And Their Utilization Of Psychiatric Emergency Services, Denton Scott
Doctoral Dissertations
Historically, patients with dual diagnosis have been subjected to ineffective treatment and negative attitudes from healthcare providers. Further, these patients are plagued with myriad afflictions that exist beyond substance abuse and mental illness. The treatments and collateral damage associated with the diagnosis impose excessive healthcare costs and can be of significant detriment to society. Largely, patients suffering from dual diagnosis do not receive adequate treatment. As such, psychiatric emergency services are frequently utilized as an alternate treatment, wherein the main focus of care is on the substance abuse alone. This study argues that solely treating the substance abuse is not …
It Is In The Cards: An Analysis Of Greeting Card Selection Through Identity And Personality, Emily Topilow
It Is In The Cards: An Analysis Of Greeting Card Selection Through Identity And Personality, Emily Topilow
Honors Projects
In this exploratory study, personal and social identity were analyzed for their effect on how consumers choose greeting cards. Factors, including personality, relationships, and identity will be qualitatively analyzed to understand people’s buying habits. Certain factors, including gender, personality, relationships, type of card, and frequency of receiving and giving cards, will be qualitatively analyzed for frequency. The two theories analyzed were the Social Identity Theory (SIT) and the Identity Theory (IT).
525 college-aged students were surveyed to examine their purchasing habits of greeting cards. The results showed that the identity of the card giver and the identity of the card …
A Meta-Analytic Review Of Cognitive Functioning In Negative And Positive Symptoms Of Schizophrenia, Tiffany Forsythe
A Meta-Analytic Review Of Cognitive Functioning In Negative And Positive Symptoms Of Schizophrenia, Tiffany Forsythe
Electronic Theses and Dissertations
The purpose of the study was to conduct two meta-analytic reviews examining cognitive functioning and schizophrenia. The first review examined the literature comparing the cognitive functioning of schizophrenic patients to healthy controls. A second review examined the cognitive functioning within schizophrenic patients, examining the differences between individuals with primarily positive symptomatology and those with primarily negative symptomatology. The first meta-analysis included 19 studies which assessed 861 schizophrenic patients and 858 healthy volunteers overall. The second meta-analysis included 10 studies comparing the cognitive functioning of 1,263 schizophrenics across positive and negative symptoms. Results of the first review indicated that healthy controls …
“I Do Have A Softer Side”: A Phenomenological Investigation Of The Prisoner-Dog Relationship In The Canine Partners For Life Training Program, Kathleen Kocherzat
“I Do Have A Softer Side”: A Phenomenological Investigation Of The Prisoner-Dog Relationship In The Canine Partners For Life Training Program, Kathleen Kocherzat
Electronic Theses and Dissertations
This qualitative study investigated the relationship between incarcerated dog handlers and the service dogs they trained. Six men at a large northeastern prison were interviewed during the summer of 2017; all were current or former dog trainers in the Canine Partners for Life (CPL) training program. The men were serving prison sentences ranging anywhere from several years to life without parole. The interviews focused on their lived experience, rasing and training puppies for a period up to eighteen months. The qualitative data consisted of approximately thirteen hours of transcribed interviews, which were then interpreted using the phenomenological psychological method developed …
The Unfolding Argument: Why Iit And Other Causal Structure Theories Cannot Explain Consciousness, Adrian Doerig, Aaron Schurger, Kathryn Hess, Michael H. Herzog
The Unfolding Argument: Why Iit And Other Causal Structure Theories Cannot Explain Consciousness, Adrian Doerig, Aaron Schurger, Kathryn Hess, Michael H. Herzog
Psychology Faculty Articles and Research
How can we explain consciousness? This question has become a vibrant topic of neuroscience research in recent decades. A large body of empirical results has been accumulated, and many theories have been proposed. Certain theories suggest that consciousness should be explained in terms of brain functions, such as accessing information in a global workspace, applying higher order to lower order representations, or predictive coding. These functions could be realized by a variety of patterns of brain connectivity. Other theories, such as Information Integration Theory (IIT) and Recurrent Processing Theory (RPT), identify causal structure with consciousness. For example, according to …
An Introduction To Transformative Inquiry: Understanding Compelling And Significant Relationships For Personal And Societal Transformation, Mark L. Mccaslin, Kelly A. Kilrea
An Introduction To Transformative Inquiry: Understanding Compelling And Significant Relationships For Personal And Societal Transformation, Mark L. Mccaslin, Kelly A. Kilrea
The Qualitative Report
Transformative inquiry is a theoretical model designed to facilitate the inquiry of important and meaningful relationships that transform and potentiate us. Creswell (2007) described the essential elements of a research agenda: the axiological, ontological, epistemological, methodological, and rhetorical. Each carries with it assumptions that hold implications for practice and research. Transformative inquiry addresses all of these elements through considerations given to deep ecology, transdisciplinarity, integral meta-theory, heuristic research, and eudaimonistic philosophy, respectively. Transformative inquiry is an approach to understanding and fostering the full range of deep and meaningful relationships from the personal to the political, and beyond. It is a …
Doing From Being: Creating Organizational Integrity Through Mindful Self-Leadership, Adam Stonebraker
Doing From Being: Creating Organizational Integrity Through Mindful Self-Leadership, Adam Stonebraker
Mindfulness Studies Theses
Mindfulness in the workplace is a subject that has seen significant growth in recent years. Mindfulness, which is rooted in ancient contemplative practice, has gained much traction among Western audiences over the last few decades. The application of Mindfulness practices is prevalent now in workplaces, where its efficacy has been well-documented, and impact has included the reduction of employee stress, increased productivity, and enhancement of one’s well-being.
The principles of mindfulness can be applied across disparate workplace settings and in nearly any situation to help bolster employees’ presence and focus in the day-to-day and retain them in the place of …
Rationale, Design, And Baseline Characteristics Of Walkit Arizona: A Factorial Randomized Trial Testing Adaptive Goals And Financial Reinforcement To Increase Walking Across Higher And Lower Walkable Neighborhoods, Marc A. Adams, Jane Hurley, Christine Phillips, Michael Todd, Siddhartha Angadi, Vincent Berardi, Melbourne F. Hovell, Steven Hooker
Rationale, Design, And Baseline Characteristics Of Walkit Arizona: A Factorial Randomized Trial Testing Adaptive Goals And Financial Reinforcement To Increase Walking Across Higher And Lower Walkable Neighborhoods, Marc A. Adams, Jane Hurley, Christine Phillips, Michael Todd, Siddhartha Angadi, Vincent Berardi, Melbourne F. Hovell, Steven Hooker
Psychology Faculty Articles and Research
Little change over the decades has been seen in adults meeting moderate-to-vigorous physical activity (MVPA) guidelines. Numerous individual-level interventions to increase MVPA have been designed, mostly static interventions without consideration for neighborhood context. Recent technologies make adaptive interventions for MVPA feasible. Unlike static interventions, adaptive intervention components (e.g., goal setting) adjust frequently to an individual's performance. Such technologies also allow for more precise delivery of “smaller, sooner incentives” that may result in greater MVPA than “larger, later incentives”. Combined, these factors could enhance MVPA adoption. Additionally, a central tenet of ecological models is that MVPA is sensitive to neighborhood environment …
The Effects Of Adenosine Antagonists On Vigilant Attention In Sleep Restricted Rats, Morgan Crewe
The Effects Of Adenosine Antagonists On Vigilant Attention In Sleep Restricted Rats, Morgan Crewe
Masters Theses, 2010-2019
The relation between chronic sleep restriction and performance on the Psychomotor Vigilance Task (PVT) have been well documented in the human literature, with chronic sleep restriction as little as 7 hours per night resulting in significant impairment in sustained attention performance measured via the PVT. Recently, an analogous version of the human PVT has been developed for use with rodent models (rPVT). Recent studies have measured the effects of sleep restriction on rPVT performance, citing similar results found in the human literature. However, few studies to date have directly examined the role of adenosine accumulation during sleep deprivation in producing …
Understanding The Help-Seeking Behaviors Of Student-Athletes: Effect Of A Multidisciplinary Healthcare Team And The Perception Of Barriers And Facilitators For Seeking Help, Lauren M. Sander
Masters Theses, 2010-2019
This study was aimed at identifying barriers and facilitators that influence help-seeking as well as the effect of implementing an integrated healthcare approach based on current recommendations. A total of 411 student-athletes from 18 intercollegiate teams at a mid-major Division I institution in the mid-Atlantic region completed a 12–item instrument comprised of ten quantitative items and two open-ended questions. The quantitative data was analyzed using SPSS software, and a constant comparative method was used to code responses from the open-ended questions. Findings suggested a prevalence of mental health challenges among student-athletes, especially overwhelming stress, struggles with time management, and anxiety. …
Children And Their Parents’ Assessment Of Postoperative Surgical Pain: Agree Or Disagree?, Olivia Kaminsky, Michelle Fortier, Brooke N. Jenkins, Robert S. Stevenson, Jeffrey I. Gold, Jeannie Zuk, Brenda Golianu, Sherrie H. Kaplan, Zeev N. Kain
Children And Their Parents’ Assessment Of Postoperative Surgical Pain: Agree Or Disagree?, Olivia Kaminsky, Michelle Fortier, Brooke N. Jenkins, Robert S. Stevenson, Jeffrey I. Gold, Jeannie Zuk, Brenda Golianu, Sherrie H. Kaplan, Zeev N. Kain
Psychology Faculty Articles and Research
Objective
The purpose of this study is to compare postoperative pain scores between children undergoing tonsillectomy and adenoidectomy (T&A) surgery and their parents, identify potential predictors for this disagreement, and determine possible impact on analgesic administration.
Methods
This is a prospective longitudinal study conducted with children undergoing outpatient T&A in 4 major tertiary hospitals and their parents. Children and their parents were enrolled prior to surgery and completed baseline psychological instruments assessing parental anxiety (STAI), parental coping style (MBSS), child temperament (EAS) and parental medication administration attitude questionnaire (MAQ). Postoperatively, parents and children completed at-home pain severity ratings (Faces Pain …
The Effects Of A Dementia Simulation Experience On Attitudes Towards People With Dementia, Micah Huckabee
The Effects Of A Dementia Simulation Experience On Attitudes Towards People With Dementia, Micah Huckabee
Health, Human Performance and Recreation Undergraduate Honors Theses
Introduction: The neurodegenerative effects of dementia resulting in cognitive and behavioral impairments is plausibly one of the reasons for a societal stigma towards individuals with dementia. Societal stigmas are associated with decreased life satisfaction, depressive symptoms, and decreased psychological well-being for stigmatized individuals. In an effort to improve attitudes towards individuals with dementia, this study utilized a dementia simulation to measure attitudinal changes after a dementia simulation. Methods: There were 33 participants in this study (13 male and 20 female) between the ages of 18 and 25. Participants completed a Dementia Attitudes Scale (DAS) survey, and then they dressed in …
A Program Evaluation Of Physician Medical Clinic’S Approach To Chronic Pain, William Summers
A Program Evaluation Of Physician Medical Clinic’S Approach To Chronic Pain, William Summers
Doctor of Psychology (PsyD)
Chronic pain costs up to $635 billion dollars annually and impacts 25.3 million adult U.S. citizens (Nahin, 2015). Treatment options have typically included opioid medications, which potentially causes harm with long-term use and has contributed to an epidemic of opioid misuse. Treatment has expanded beyond monotherapy to include holistic approaches to health, such as occupational therapy and mental health therapy. The present study sought to evaluate the effectiveness of group therapy as it is conducted in a rural Oregon clinic using the Quadruple Aim to measure treatment outcomes (Bodenheimer, & Sinsky, 2014). Participants diagnosed with chronic pain and placed on …
The Effects Of Two Novel Anti-Inflammatory Compounds On Prepulse Inhibition And Neural Microglia Cell Activation In A Rodent Model Of Schizophrenia, Heath W. Shelton
The Effects Of Two Novel Anti-Inflammatory Compounds On Prepulse Inhibition And Neural Microglia Cell Activation In A Rodent Model Of Schizophrenia, Heath W. Shelton
Electronic Theses and Dissertations
Recent studies have shown elevated neuroinflammation in a large subset of individuals diagnosed with schizophrenia. A pro-inflammatory cytokine, tumor necrosis factor-alpha (TNFα), has been directly linked to this neuroinflammation. This study examined the effects of two TNFα modulators (PD2024 and PD340) produced by our collaborators at P2D Bioscience, Inc., to alleviate auditory sensorimotor gating deficits and reduce microglial cell activation present in the polyinosinic:polycytidylic (Poly I:C) rodent model of schizophrenia. Auditory sensorimotor gating was assessed using prepulse inhibition and microglial activation was examined and quantified using immunohistochemistry and confocal microscopy, respectively. Both PD2024 and PD340 alleviated auditory sensorimotor gating deficits …
Associations Of First Trimester Co-Use Of Tobacco And Cannabis With Prenatal Immune Response And Psychosocial Well-Being, Kristin Ashford, Amanda Fallin-Bennett, Andrea Mccubbin, Amanda T. Wiggins, Sheila Barnhart, Joshua A. Lile
Associations Of First Trimester Co-Use Of Tobacco And Cannabis With Prenatal Immune Response And Psychosocial Well-Being, Kristin Ashford, Amanda Fallin-Bennett, Andrea Mccubbin, Amanda T. Wiggins, Sheila Barnhart, Joshua A. Lile
Perinatal Research and Wellness Center Faculty Publications
PURPOSE: This study aims to describe the association of first trimester co-use of tobacco and cannabis with maternal immune response and psychosocial well-being, relative to tobacco use only.
METHODS: A preliminary midpoint analysis included 138 pregnant women with biologically verified tobacco use, 38 of whom (28%) also tested positive for recent cannabis use. Maternal perceived stress (Perceived Stress Scale), depressive symptoms (Edinburgh Postnatal Depression Scale), and serum immune markers (IL-1β, IL-2, IL-6, IL-8, IL-10, TNFα, CRP, MMP8), were collected, although cytokine data were only available for 122 women.
RESULTS: Participant average age was 29.1 years, approximately half had a high …