Psychiatry and Psychology Commons^™

The Last Of Us In Therapy: How Mind-Controlling Fungi And Gut Bacteria Affect Your Mental Health, Anastasia Lyon

Journal of Pharmacology & Nutritional Sciences

The "psilocybiome" represents the mutually beneficial relationship between ourselves, our bacteria, and psychedelic drugs. This short review briefly discusses the benefits and limitations surrounding the potential for psychedelic therapy to synergize with gut bacteria to help regulate and maintain proper balance in the immune system, diet, and stress levels. Psychedelic therapy is a novel treatment strategy that has the potential to improve patient mental health, and, by identifying the types of gut bacteria present in patients, it can aid in personalizing medicine by determining how well their "psilocybiome" may respond.

Tf-Cbt Training Augmented With A Self-Care Focus: Understanding Facilitators And Barriers To Treatment Implementation., Julie P. Harrison, Esther Deblinger, Elisabeth Pollio, Beth Cooper, Robert A Steer

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Clinicians working with youth exposed to trauma may be at increased risk for experiencing elevated levels of stress and symptoms of secondary traumatic stress, which can negatively impact clinician wellbeing and ultimately contribute to reduced access to quality care for clients. An innovative Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) training incorporating self-care practices (i.e., Practice What You Preach; PWYP) was developed to help facilitate the implementation of TF-CBT and to enhance clinicians' coping and decrease stress. The primary purpose of this study was to determine whether the PWYP-augmented training met three Objectives: (1) increase clinicians' feelings of TF-CBT competency; (2) improve …

Enacting Stories: Discovering Parallels Of Narrative And Expressive Therapies, A Literature Review, Zoe Reddig

Expressive Therapies Capstone Theses

This literature review will analyze the use of narrative therapy (NT) techniques, dance/movement therapy (DMT) techniques, and expressive therapy (ET) techniques in an effort to distinguish where theoretical parallels exist between these methods of counsel. Narrative therapy is a postmodern framework of counseling that assists clients in resisting damaging stories that have been embedded through bioecological systems of exposure throughout development. Narrative therapy structures its philosophy through processes of externalization and deconstruction, and encourages the process of reframing or re-authoring one’s personal self-narrative. At their core, DMT and ET already utilize components of foundational NT practices, through processes of enactment, …

Transcendence: Exploring The Connections Between Transgender/Gender Non-Conforming Identities And Experiences Of Nature Through Art, Mc Jackson

Undergraduate Theses

“Transcendence: Exploring the connections between transgender/gender non-conforming identities and experiences of nature through art” is the written portion of a creative thesis revolving around an immersive art installation and short film. Transcendence, the installation, was created to promote connection by exploring the overlap between transgender and gender non-conforming (GNC) experiences and experiences of nature. Part of this installation is a short film of interviews conducted with transgender and GNC individuals about nature, their gender experiences, and the transcendent nature of the two. The written thesis analyzes existing literature on nature as a restorative, therapeutic, spiritual setting, offers insight into …

Targeting Social Connection In The Context Of Trauma: Functional Outcomes And Mechanisms Of Change, Andrew J. Smith, David Pincus, Bernard P. Ricca

Psychology Faculty Articles and Research

The current study presents and preliminarily tests a brief, theory driven intervention designed to target social connectivity as a transdiagnostic mechanism of health. We tested four hypotheses to examine whether and how explicitly targeting social behavior engagement (activating values-led behaviors towards specific network members) may improve other downstream aspects of social connectivity (i.e., social cognitions measured as loneliness, interpersonal closeness, perceived social support) and functioning (quality of life [QOL] and posttraumatic stress symptoms [PTS]). Methods. Participants included 15 patients (10 veterans, 5 firefighters) who completed the six-session intervention. Demographics: age (M = 46, SD = 17), 87% male, race (80% …

Effect Of Motivational Music On Peak Knee Torque, Perceived Exertion, And Enjoyment In College-Aged Individuals, Arianna Cole

Undergraduate Honors Theses

There is a general consensus in previous and current literature that the incorporation of music in exercise has the potential to benefit performance (Karageorghis 2020; Terry et al. 2019). Research on the potential benefits of music in rehabilitative exercise has become more prevalent but has mainly focused on music and the rehabilitation of neurological conditions such as Parkinson's disease or stroke (Craig et al. 2015; De Bartolo et al. 2020; Grau-Sánchez et al. 2022; Katlen da Silva et al. 2021; Särkämö 2018). Research in a more general rehabilitative setting has not been explored as widely and this is the aim …

Post-Traumatic Stress Symptoms And Their Role In Intimate Relationships: Do Ptsd Symptoms Moderate The Relationship Between Conflict And Aggression In Military Servicepeople?, Hannah M. Breen

ETD Archive

Military servicepeople often find themselves facing symptoms of Post-Traumatic Stress Disorder (PTSD) following their service. The symptoms of PTSD can impact the functioning of servicepeople’s intimate relationships, particularly in the aspect of conflict and aggression. The present study aimed to assess the effect of a military-involved partner’s PTSD symptoms on the association between relationship conflict and aggression from the perspectives of both partners. Data were collected from 112 military-involved individuals (active-duty or veteran) and 16 couples (one military-involved partner and one civilian partner) who participated in an online survey which collected data on their romantic relationships. It was hypothesized that …

Adolescents With Family History Of Alcohol-Use Disorders Have Reduced Structural Coherence Of Anterior Insula To Nucleus Accumbens Tract, Grace Wood

Psychological Science Undergraduate Honors Theses

Genetics play a significant role in predisposition towards alcohol use disorders. Analyzing the neural phenotypes related to alcohol use disorder development could allow researchers to predict one’s predisposition. The anterior insula (AIns) contributes to binge drinking tendencies while exhibiting downstream signaling towards the nucleus accumbens (NAcc). Recent research has examined this relationship simultaneously with alcohol consumption, but the genetic effect of the AIns and NAcc functional relationship prior to alcohol consumption has yet to be examined. In this study, we used data from the Adolescent Brain Cognitive Development (ABCD) study to analyze the structural coherence of the AIns to NAcc …

Effects Of Parental Alcoholism On Adolescent Development, Diana Michel-Gonzales

Whittier Scholars Program

Studies assessed the magnitude and specificity of parental alcoholism as a risk factor for internalizing symptomatology, externalizing symptomatology, and alcohol and drug use in adolescence. The results show that alcoholism is a moderate risk factor. The outcome measure has a different risk specificity. The risk of alcoholism is caused by parental psychopathology and environmental stress. The father's alcoholism was a risk for alcohol use that was beyond the effects of stress and family turmoil. The children of problem drinkers are affected by externalities. When designing and financing addiction treatment programs, long-term consequences of alcohol misuse should be taken into account. …

An Erp Measure Of Non-Conscious Memory Reveals Dissociable Implicit Processes In Human Recognition Using An Open-Source Automated Analytic Pipeline, Richard J. Addante, Javier Lopez-Calderon, Nathaniel Allen, Carter Luck, Alana Muller, Lindsey Sirianni, Cory S. Inman, Daniel L. Drane

Psychology Faculty Publications

Non-conscious processing of human memory has traditionally been difficult to objectively measure and thus understand. A prior study on a group of hippocampal amnesia (N = 3) patients and healthy controls (N = 6) used a novel procedure for capturing neural correlates of implicit memory using event-related potentials (ERPs): old and new items were equated for varying levels of memory awareness, with ERP differences observed from 400 to 800 ms in bilateral parietal regions that were hippocampal-dependent. The current investigation sought to address the limitations of that study by increasing the sample of healthy subjects (N = 54), applying new …

Social Media And Wellbeing, Aditya Adsule

Honors College Theses

This psychology thesis paper investigates the existing body of scientific literature surrounding the effects of social media on the wellbeing of adolescents and adults ages 18-29. The current body of scientific literature supports the overall finding that social media has a negative impact not only on mental health, but on physical health. There are also key findings showing the impact of social media on other facets of life such as sleep patterns, social interactions, and physical activity. Current intervention therapies need to be revisited and the DSM categorization of social media addiction needs to be investigated further.

What Cognitive Processes Drive Attentional Bias, And How Does Stress Affect Them?, Colton L. Hunter

Graduate Theses and Dissertations

Attentional biases toward or away from emotionally evocative stimuli have been well documented and related to clinical outcomes such as social anxiety. Some work has suggested that stress modulates attentional biases, but there are a number of inconsistencies in this literature regarding the direction of that modulation, highlighting a need to examine moderators of that effect. Sex differences in stress effects could potentially explain this inconsistency, as acute stress can affect males and females differently. It is also possible that stress differentially influences multiple component processes underpinning attentional bias, but these processes have not been well character, and to date …

Therapeutic Approaches To Working With Perinatal Loss Clients: A Grounded Theory Study, Heather H. Olivier

LSU New Orleans Theses and Dissertations

Perinatal loss (i.e., miscarriage, stillbirth, termination, and infant death) is commonly referred to in the literature as an invisible loss, non-loss, and even medical event. It is an ambiguous loss exhibiting the dialectical contradiction between the physical absence and psychological presence of the baby accompanied by disenfranchised grief, a reaction to a loss that is unacknowledged by society. Despite the likelihood of mental health clinicians working with clients who have experienced perinatal loss, there has yet to be a therapeutic model designed specifically for the unique grief and trauma reactions presented in this population. Existing grief models do not address …

Resilience To Stress Across The Lifespan: Childhood Maltreatment, Heart Rate Variability, And Bereavement, Michelle A Chen, Robert Suchting, Julian F Thayer, Christopher P Fagundes

Faculty, Staff and Student Publications

Following a stressful life event, there is considerable variation in how individuals respond and adapt. Multiple models of risk and resilience show that adverse childhood experiences may be associated with an individual's response to stress later in life. While there is considerable support that early adversity can sensitize the stress response system and lead to adverse outcomes later in life, there is mounting evidence that in adolescence and young adulthood, certain biological predispositions to stress may be associated with resilience in the context of subsequent stressors. In this study, we evaluated how individual differences in vagally mediated heart rate variability …

Circumventing Ableism: A Grounded Theory Study Exploring Caregiver Strategies To Promote A Positive Identity, June Furr

All Dissertations

This qualitative research study explores how caregivers and persons with disabilities navigate the rhetoric of disability and caregiving through the interviews of fifteen caregivers and fifteen persons with disabilities using the lens of grounded theory and Burke’s (1952) dramatistic pentad. Significant findings describe how focused disability description can circumvent ableism when rhetorical resources that assist caregivers and persons with disabilities to navigate the rhetoric in disability descriptions are provided. Disability description theory includes the three stages that define, collaborate and revise, and practice and apply a disability description. This qualitative research offers an introduction into the phenomenon of …

Children’S Disclosure Of School Bullying: The Relation Between Peer Victimization, Internalizing Symptoms, Negative Affect, And Gender, Julia L. Kiefer

Graduate Theses and Dissertations

Children who are bullied by their peers are at risk for several negative developmental outcomes and are therefore advised to tell an adult when they are. However, victims of school bullying are often reluctant to disclose to adults that they are being bullied. Some bullied children also experience symptoms of anxiety or depression, which could further reduce their likelihood of telling an adult. In this study, I tested the degree to which children’s internalizing symptoms predicted their likelihood of telling adults about being bullied at school, and if this relation was exacerbated by children’s negative feelings associated with telling an …

Depression, Stress And Regional Cerebral Blood Flow, Joshua Chiappelli, Bhim M Adhikari, Mark D Kvarta, Heather A Bruce, Eric L Goldwaser, Yizhou Ma, Shuo Chen, Seth Ament, Alan R Shuldiner, Braxton D Mitchell, Peter Kochunov, Danny Jj Wang, L Elliot Hong

Faculty, Staff and Student Publications

Decreased cerebral blood flow (CBF) may be an important mechanism associated with depression. In this study we aimed to determine if the association of CBF and depression is dependent on current level of depression or the tendency to experience depression over time (trait depression), and if CBF is influenced by depression-related factors such as stressful life experiences and antidepressant medication use. CBF was measured in 254 participants from the Amish Connectome Project (age 18-76, 99 men and 154 women) using arterial spin labeling. All participants underwent assessment of symptoms of depression measured with the Beck Depression Inventory and Maryland Trait …

Association Between The Epigenetic Lifespan Predictor Grimage And History Of Suicide Attempt In Bipolar Disorder, Camila N C Lima, Emese H C Kovács, Salahudeen Mirza, Alexandra Del Favero-Campbell, Alexandre Paim Diaz, Joao Quevedo, Benney M R Argue, Jenny Gringer Richards, Aislinn Williams, John A Wemmie, Vincent A Magnotta, Jess G Fiedorowicz, Jair C Soares, Marie E Gaine, Gabriel R Fries

Faculty, Staff and Student Publications

Bipolar disorder (BD) has been previously associated with premature mortality and aging, including acceleration of epigenetic aging. Suicide attempts (SA) are greatly elevated in BD and are associated with decreased lifespan, biological aging, and poorer clinical outcomes. We investigated the relationship between GrimAge, an epigenetic clock trained on time-to-death and associated with mortality and lifespan, and SA in two independent cohorts of BD individuals (discovery cohort - controls (n = 50), BD individuals with (n = 77, BD/SA) and without (n = 67, BD/non-SA) lifetime history of SA; replication cohort - BD/SA (n = 48) and BD/non-SA (n = 47)). …

Emotional Reactivity Predicts Dissociation In Maltreated Youth, Jaelin Isquith, Kinsey Ellis

Undergraduate Research Symposium Posters

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR) defines dissociation as “disruption in the usually integrated functions of consciousness, memory, identity or perception of the environment”11. Dissociation most commonly occurs after a traumatic experience and can take many forms; Subtypes include dissociative amnesia, absorption and imaginative involvement, passive influence, and depersonalization and derealization. Dissociation has been linked to several negative outcomes such as increased risk for development of personality disorders, suicidal ideation, and self-harm2,3. Risk factors for dissociation have been understudied in child and adolescent populations. One factor that has been found to be related to severity of dissociative …

Experiencing Moral Distress Within The Intimate Partner Violence & Sexual Assault Workforce, Rachel J Voth Schrag, Sophia Fantus, Sarah Leat, Saltanat Childress, Leila Wood

Faculty, Staff and Student Publications

PURPOSE: Moral distress (MD) refers to the psychological disequilibrium that emerges when institutional policies and/or practices conflict with an individual's professional values and ethics. MD has been interrogated frequently in health care and ancillary medical settings, and has been identified as a critical barrier to enhanced organizational climate and patient care. However, little work has investigated experiences of MD among members of the intimate partner violence (IPV) and sexual violence (SV) workforce.

METHODS: This study investigates MD in a sample of IPV and SV service providers via secondary analysis of 33 qualitative interviews conducted with service providers in the summer …

Dental Fear, Anxiety, And Phobia – Behavioral Management And Implications For Dentists, Nadya Tsetsova Avramova

Journal of Mind and Medical Sciences

Clinical management of patients with dental fear, anxiety, and phobia could be a major challenge to daily practice of dental professionals. The aim of the current review was to expand the modern consideration with respect to these issues, and therefore to discuss basic approaches and psychological techniques for management of oral health behaviors that should be employed in dentistry. This paper presents detailed description of the characteristics of dentist-patient therapeutic relationship as well as the most used techniques to cope with dental fear, anxiety, and phobia - relaxation techniques, cognitive-behavioral therapy (CBT), hypnosis and melotherapy. We can still argue that …

Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information And Proximity To Others, Beth Durkin

Honors Projects

In response to the COVID-19 pandemic, many people expressed a lax attitude to the policies put in place to keep the public safe despite the high risk of infection and its devastating effects on health across the United States. It is possible that this response may be partially due to a “numbness to numbers,” a phenomenon that describes diminished empathy for a large group of people experiencing a negative event (eg. COVID-19). The present study explored the relationship between levels of situational empathy and the medium of exposure to COVID-19 mortality information (eg. personal story or fact sheet) in an …

Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Given the recently renewed interest in using psychedelics to aid in the treatment of psychological disorders, we aimed to examine the impact of psilocybin, a 5-HT_2A agonist, on learning and memory in rodents. Previous work has demonstrated that psilocybin and other 5-HT_2A agonists can enhance fear conditioning, fear extinction, and novel object recognition (NOR). Thus, we predicted that low doses of psilocybin would enhance inhibitory avoidance (IA) and NOR memory. In the first experiment, adult male and female Sprague-Dawley rats underwent step-through IA training (involving 0.45, 0.65, or 1 mA scrambled footshock) and were injected intraperitoneally (i.p.) with …

Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most research examining the impact of stress on learning and memory has exposed participants to a stressor and measured how it affects learning and memory for unrelated material (e.g., list of words). Such work has been helpful, but it has not been the most translational to the human condition. When considering phenomena such as intrusive memories in post-traumatic stress disorder (PTSD) or an eyewitness's memory for a crime, it is most useful to know what an individual remembers about the stress experience itself, not unrelated information. In prior work, investigators used a modified version of the Trier Social Stress Test …

Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz

ONU Student Research Colloquium

Many researchers approach the etiology of trauma-, stressor-, and anxiety-related mental disorders from the perspective of classical conditioning processes gone awry. According to this view, abnormal associative relationships between conditioned and unconditioned stimuli may underlie pathological anxiety and result in unusually intense fear memories or fear memories that cannot be properly extinguished. Recent work has expanded on this view by showing that many psychological disorders involving pathological anxiety are associated with an exaggerated form of stimulus generalization, leading individuals with such disorders to respond with fear and anxiety to a variety of contexts and cues that should not be threatening. …

Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Pharmacotherapy for stress-related psychological disorders remains inadequate. Patients who are treated with conventional pharmacological agents frequently report negligeable symptom reduction, and, in most cases, less than 50% experience full remission. Clearly, there is a need for additional pharmaceutical research into both established and novel approaches to alleviate these conditions. Over the past several years, there has been a renewed interest in the use of psychedelics to aid in the treatment of psychological disorders. Several studies have reported promising results in patients with major depression, anxiety disorders, and post-traumatic stress disorder (PTSD) following treatment with psychedelic agents such as lysergic acid …

The Effects Of School-Based Art Therapy On Depressed Adolescents, Jasmine Nicolas

Nursing | Student Research Posters

Depression in adolescents is associated with deficient behavioral and health outcomes (Fletcher, 2019). Art therapy has been shown to be effective in treating mental health condition such as depression. A student’s academic success heavily depends on treating their depression. Community health nurses can play a vital role in advocating for adequate mental health support to improve a student’s overall well-being and academic success. The literature review contains six articles on the prevalence and impact of depression among adolescents, art therapy as an intervention for improving psychological outcomes and resilience among adolescents, and experiences of adolescent clients in art therapy within …

Mechanisms Linking Threat- And Deprivation-Related Childhood Adversity And Depression: The Biopsychosocial Model, Cut N. Kemala, Marijtje L.A. Jongsma, Donny Hendrawan, Eni Becker

Psychological Research on Urban Society

Childhood adversity involves a wide range of negative experiences that pose a serious threat to a child’s wellbeing. It has been consistently shown to predict (chronic) depression in subsequent stages of development, but mechanisms underlying the relationship are still less clear. Moving from a cumulative approach of lumping heterogeneous categories of childhood adversity to a dimensional approach of classifying negative experiences into two major dimensions (threat and deprivation) has facilitated the identification of specific processes by which childhood adversity can predict depression. This review aims to provide an integrative overview of how childhood adversity increases the risk for depression using …

Brain Deficit Patterns Of Metabolic Illnesses Overlap With Those For Major Depressive Disorder: A New Metric Of Brain Metabolic Disease, Kathryn S Hatch, Si Gao, Yizhou Ma, Alessandro Russo, Neda Jahanshad, Paul M Thompson, Bhim M Adhikari, Heather Bruce, Andrew Van Der Vaart, Aristeidis Sotiras, Mark D Kvarta, Thomas E Nichols, Lianne Schmaal, L Elliot Hong, Peter Kochunov

Faculty, Staff and Student Publications

Metabolic illnesses (MET) are detrimental to brain integrity and are common comorbidities in patients with mental illnesses, including major depressive disorder (MDD). We quantified effects of MET on standard regional brain morphometric measures from 3D brain MRI as well as diffusion MRI in a large sample of UK BioBank participants. The pattern of regional effect sizes of MET in non-psychiatric UKBB subjects was significantly correlated with the spatial profile of regional effects reported by the largest meta-analyses in MDD but not in bipolar disorder, schizophrenia or Alzheimer's disease. We used a regional vulnerability index (RVI) for MET (RVI-MET) to measure …

Time Of Day Preferences And Daily Temporal Consistency For Predicting The Sustained Use Of A Commercial Meditation App: Longitudinal Observational Study, Vincent Berardi, Ryan Fowers, Gavriella Rubin, Chad Stecher

Psychology Faculty Articles and Research

Background: The intensive data typically collected by mobile health (mHealth) apps allows factors associated with persistent use to be investigated, which is an important objective given users’ well-known struggles with sustaining healthy behavior.

Objective: Data from a commercial meditation app (n=14,879; 899,071 total app uses) were analyzed to assess the validity of commonly given habit formation advice to meditate at the same time every day, preferably in the morning.

Methods: First, the change in probability of meditating in 4 nonoverlapping time windows (morning, midday, evening, and late night) on a given day over the first 180 days …