Psychiatry and Psychology Commons^™

Exploring Epigenetic Regulation Of Fear Memory And Biomarkers Associated With Post-Traumatic Stress Disorder, Stephanie A. Maddox, Glenn E. Schafe, Kerry J. Ressler

Publications and Research

This review examines recent work on epigenetic mechanisms underlying animal models of fear learning as well as its translational implications in disorders of fear regulation, such as Post-traumatic Stress Disorder (PTSD). Specifically, we will examine work outlining roles of differential histone acetylation and DNA-methylation associated with consolidation, reconsolidation, and extinction in Pavlovian fear paradigms. We then focus on the numerous studies examining the epigenetic modifications of the Brain-derived neurotrophin factor (BDNF) pathway and the extension of these findings from animal models to recent work in human clinical populations. We will also review recently published data on FKBP5 regulation of …

Treatment Of Psychiatric Inpatients With Relationship Dysfunction Using A Short Term Cognitive Interpersonal Intervention: A Pilot Study, Tamra Rasberry

Doctoral Dissertations and Projects

Relationship conflict for the psychiatric patient can have significant detrimental effects. There are specific types of interactions that can increase conflict and predict the potential for relapse; these have been identified by research and designated as components of Expressed Emotion (EE). Cognitive Behavioral Therapy (CBT) and Interpersonal Therapy (IPT) have been very effective when targeting specific psychiatric diagnoses, but less effective when addressing relationship conflict. The majority of studies addressing relationship conflict have taken place in an outpatient, long-term setting. There is limited research that utilizes an inpatient short-term intensive therapy with relationship conflict as its sole focus, targeting areas …

Research Brief: "Anxiety, Social Support, And Physical Health In A Sample Of Spouses Of Oef/Oif Service Members", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study focused on anxiety disorders in military spouses and their comorbidity with physical health, identifying the potential for such a comorbidity to worsen over time. The study suggests the importance of recognizing, identifying, and supporting these members of the community. The future research proposed includes objectively measuring this study's outcomes, examining ALL of the military branches, and ways of treating these situations of anxiety disorders.

Research Brief: "Partnering With Communities To Address The Mental Health Needs Of Rural Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This research focuses on veterans in rural communities who have less access to mental health providers. The Yellow Ribbon Task Force program promoted and encouraged engagement in mental health care for veterans in rural communities, although future policies should enhance already existing clinical practices to increase standards for care. For further study, researchers should focus on evaluating initial program implementation and pilot testing in a variety of states and rural populations.

Diagnostic Interaction: First-Person Patient Narratives On Hacking's Looping Effects And The Normative Status Of Psychiatric Nosology, Corinne Jager

Honors College Theses

What is the interaction between a psychiatric patient and their diagnosis? How do they respond to being classified? A number of philosophical theories attempt to explain the interaction between the diagnosed patient and their classification. Ian Hacking develops an account of interaction which holds that objects of human science classification are influenced by the awareness of the classification in a way that changes both the classification and its object. Hacking thinks that psychiatric patients are “interactive kinds” whose awareness of their classification causes changes in the individuals' experience of themselves, and thus changes in their classification. Hacking claims that these …

Gait Analysis Of Teenagers And Young Adults Diagnosed With Autism & Severe Verbal Communication Disorders, Michael J. Weiss, Matthew F. Moran, Mary E. Parker, John T. Foley

All PTHMS Faculty Publications

Both movement differences and disorders are common within autism spectrum disorders (ASD). These differences have wide and heterogeneous variability among different ages and sub-groups all diagnosed with ASD. Gait was studied in a more homogeneously identified group of nine teenagers and young adults who scored as “severe” in both measures of verbal communication and overall rating of Autism on the Childhood Autism Rating Scales (CARS). The ASD individuals were compared to a group of typically developing university undergraduates of similar ages. All participants walked a distance of 6-meters across a GAITRite (GR) electronic walkway for six trials. The ASD and …

Two-Legged Hopping In Autism Spectrum Disorders, Matthew F. Moran, John T. Foley, Mary E. Parker, Michael J. Weiss

All PTHMS Faculty Publications

Sensory processing deficits are common within autism spectrum disorders (ASD). Deficits have a heterogeneous dispersion across the spectrum and multimodal processing tasks are thought to magnify integration difficulties. Two-legged hopping in place in sync with an auditory cue (2.3, 3.0 Hz) was studied in a group of six individuals with expressive language impaired ASD (ELI-ASD) and an age-matched control group. Vertical ground reaction force data were collected and discrete Fourier transforms were utilized to determine dominant hopping cadence. Effective leg stiffness was computed through a mass-spring model representation. The ELI-ASD group were unsuccessful in matching their hopping cadence (2.21 ± …

Dyscalculia: Characteristics, Causes, And Treatments, Gavin R. Price, Daniel Ansari

Numeracy

Developmental Dyscalculia (DD) is a learning disorder affecting the ability to acquire school-level arithmetic skills, affecting approximately 3-6% of individuals. Progress in understanding the root causes of DD and how best to treat it have been impeded by lack of widespread research and variation in characterizations of the disorder across studies. However, recent years have witnessed significant growth in the field, and a growing body of behavioral and neuroimaging evidence now points to an underlying deficit in the representation and processing of numerical magnitude information as a potential core deficit in DD. An additional product of the recent progress in …

Dead Men, Walking: Actors, Networks, And Actualized Metaphors In Mrs. Dalloway And Raymond, Elizabeth Outka

English Faculty Publications

This article takes up Rita Felski’s recent call to modernists to explore how Bruno Latour’s latest work on actor-network theory might be adapted for literary studies. It examines two accounts of World War I soldiers who (allegedly) return from the dead in material form: Virginia Woolf’s fictional account of Septimus Smith, who is convinced his friend Evans has come back from the dead, and Oliver Lodge’s best-selling memoir, Raymond, or Life and Death, which recounts in detail how Lodge believed his dead son sent messages to the family to assure them of his continued material existence. That these moments …

Is Modafinil (Provigil®) Effective In Improving Cognitive Function In Adults With Narcolepsy?, Stephanie V. Bui

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not modafinil (Provigil®) is effective in improving cognitive function in adults with narcolepsy.

STUDY DESIGN: Review of all English language primary randomized controlled trials from 1996 to 2010.

DATA SOURCES: Double-blind, randomized controlled trials that compared modafinil (Provigil®) to a visually matched placebo were found using OVID, MEDLINE, and Cochrane Databases.

OUTCOME(S) MEASURED: Each of the three trials assessed the effect of modafinil on cognitive and executive function by Low-Resolution Brain Electromagnetic Tomography (LORETA), and the following assessment tools: Epworth Sleepiness Scale (ESS), Multiple Sleep …

Relation Between Optimism And Lipids In Midlife, Julia K. Boehm, David R. Williams, Eric B. Rimm, Carol Ryff, Laura D. Kubzansky

Psychology Faculty Articles and Research

This research examined optimism’s relationship with total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, and triglycerides. The hypothesis that optimism is associated with a healthier lipid profile was tested. Participants were 990 mostly white men and women from the Midlife in the United States study who were on average 55.1 years old. Optimism was assessed by self-report with the Life Orientation Test. A fasting blood sample was used to assess serum lipid levels. Linear and logistic regression models examined the cross-sectional association between optimism and lipids accounting for covariates such as demographic characteristics (e.g., education) and …

Expression Of Borderline Personality Disorder Symptoms Across The Ovulatory Cycle: A Multilevel Investigation, Tory A. Eisenlohr-Moul

Theses and Dissertations--Psychology

Borderline Personality Disorder (BPD) is a disabling condition characterized by chronic emotion dysregulation and behavioral impulsivity. Prospective studies that test proposed mechanisms of within-person change in BPD hold the key to improving symptom predictability and control in this disorder. A small body of evidence suggests that fluctuations in estradiol such as those occurring naturally at ovulation during the monthly female reproductive cycle may increase symptoms in women with BPD (DeSoto et al., 2003). Furthermore, there is preliminary evidence that both self-esteem and feelings of social rejection are highest at ovulation, when estradiol peaks (Durante and Hill, 2009; Eisenlohr-Moul et al., …

Autonomic And Behavioral Reactivity To An Acute Laboratory Stressor, Jeremy C. Peres

University of New Orleans Theses and Dissertations

Stress has been widely shown to directly influence people’s emotional and behavioral processing as well as their underlying biological systems. This project examined physiological and behavioral responses as indicators of stress and coping in the context of a psychosocial stressor in a controlled laboratory setting. We examined the association between indicators of behavioral coping and underlying physiological reactivity within participants while experiencing stress. Participants included 68 emerging adults. Physiological measures include autonomic biomarkers (e.g., heart-rate, skin conductance) at rest and during the stressor while behavioral indicators that were coded include acute verbal and non-verbal actions exhibited by participants during the …

Parametric Studies Of Antipsychotic-Induced Sensitization In The Conditioned Avoidance Response Model: Roles Of Number Of Drug Exposure, Drug Dose, And Test–Retest Interval, Natashia Swalve, Ming Li

Department of Psychology: Faculty Publications

Repeated haloperidol and olanzapine treatment produces an enhanced disruption of avoidance responding, a validated measure of antipsychotic activity. Experimental parameters affecting this sensitization-like effect have not been thoroughly examined. The present study investigated the role of three parameters (number of injections, dose, and interval between initial exposure and challenge) in antipsychotic sensitization in the conditioned avoidance response paradigm. Well-trained Sprague–Dawley rats received different numbers of drug treatment (1–5 days) or different doses of haloperidol (0.025–0.10 mg/kg, subcutaneously) or olanzapine (0.5–2.0 mg/kg, subcutaneously). After certain time intervals (4, 10 or 17 days), they were tested for the expression of haloperidol or …

The American Psychiatric Association’S Guideline For Major Depressive Disorder: A Commentary, Lisa Cosgrove, Allen F. Shaughnessy, Emily E. Wheeler, Kirsten E. Austad, Irving Kirsch, Harold J. Bursztajn

Counseling, School Psychology & Sport Faculty Publication Series

The American Psychiatric Association (APA) published a new guideline for Major Depressive Disorder (MDD) which will undoubtedly be used by many practitioners to guide clinical decision-making. In fact, it is non-psychiatrist clinicians who prescribe the majority of antidepressants (AD). We review the APA’s most recent guideline on MDD and report on our observations.

Preventing Mental Distress In The Military, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon D. Elhai, J. Donald Richardson

CRDCN Research Highlight/RCCDR en évidence

No abstract provided.

Culture Ontogeny: Lifespan Development Of Religion And The Ethics Of Spiritual Counselling, Glen Milstein, Amy Manierre

Publications and Research

The counsellor has an ethical obligation to treat the whole person. Humans are cultural beings and the foundation of most cultures is religion. Religion and culture are received from our early relation~ ships and modified through later relationships across the lifespan. The paper introduces the term "culture ontogeny" to emphasize that this is a biological process wherein abstract ideas of culture and religion become material in the developing neurophysiology of each brain. A framework and methods are offered to examine the changing roles of religion in clients' emotional self~ structure, inclusive of those who describe themselves as spiritual, not religious. …

Using The Scrambled Sentences Test To Examine Relationships Between Cognitive Bias, Thought Suppression And Borderline Personality Features, Paul Jefferson Geiger

Theses and Dissertations--Psychology

Cognitive bias and thought suppression are two maladaptive patterns of thinking that have been associated with borderline personality disorder (BPD). Negative cognitive biases related to BPD include thoughts that they are bad, powerless, or vulnerable and that the world is dangerous. Thought suppression is a maladaptive emotion regulation strategy where unwanted thoughts are intentionally pushed out of one’s consciousness. However, previous research has connected thought suppression and cognitive biases to BPD only via self-report measures. The present study examined whether a laboratory task meant to measure cognitive bias and thought suppression (Scrambled Sentences Test) would predict BPD features over and …

The Reintegration Myth: An Interpretive Phenomenological Inquiry Into The Reentry Experiences Of Air Force Reservists Returning From Afghanistan, Brent French

Antioch University Dissertations & Theses

This project documents the 18-month reentry trajectory of nine (including the author) United States Air Force Reservists returning home from a six-month deployment to Afghanistan in 2009 and 2010. Compared with their Active Component peers, members of the Reserve Component are more likely to be diagnosed with adaptive disorders and have an elevated risk of unemployment, substance abuse, and suicide. Since a critical difference between Active and Reserve Component members is the dual-status of reservists as both military members and civilians, this project sought to better understand this duality within the context of nonpathological reentry. This required an interdisciplinary approach …

Depicting Estimates Using The Intercept In Meta-Regression Models: The Moving Constant Technique, Blair T. Johnson Dr., Tania B. Huedo-Medina Dr.

CHIP Documents

In any scientific discipline, the ability to portray research patterns graphically often aids greatly in interpreting a phenomenon. In part to depict phenomena, the statistics and capabilities of meta-analytic models have grown increasingly sophisticated. Accordingly, this article details how to move the constant in weighted meta-analysis regression models (viz. “meta-regression”) to illuminate the patterns in such models across a range of complexities. Although it is commonly ignored in practice, the constant (or intercept) in such models can be indispensible when it is not relegated to its usual static role. The moving constant technique makes possible estimates and confidence intervals at …

The Effects Of Working Memory On High And Low Working Memory Capacity, Colleen M. Parks, Christine Agnir

Festival of Communities: UG Symposium (Posters)

Acute stress is a factor that impairs working memory (McHugh et al.,2010). Emotional stimuli have been used in long-term memory studies. The emotional content of information is important in long-term memory studies that have focused on stress, but it is unknown if the valence of the stimuli matter for working memory tasks. Little research is know to use emotional pictures of N-back stimuli. Our goal is to determine whether these factors may significantly disrupt the working memory process of efficiently completing complex tasks.

Nietzsche And Lou, Eros And Art : On Lou’S Triangles And The « Exquisite Dream » Of Sacro Monte, Babette Babich

Research Resources

No abstract provided.

How To Win Jobs And Influence Interviewers: A Psychological Exploration Of Job Interview Best Practices, C. Diggory Rycroft

CMC Senior Theses

Navigating the formal employment interview has long been an imposing obstacle to acquiring gainful employment in the white-collar world, particularly that of the United States. Conventional wisdom offers a wide variety of suggestions for achieving the best possible outcomes from the interview, for instance smiling, having a firm handshake, demonstrating interest in the company, and “being yourself.” Much of this common knowledge is based primarily in intuition and carry-over from standard conversational best practices, rather than rigorous empirical testing. As such, this literature review sets out to bring together the various works of interview research that currently exist, with the …

A Prospective Study Of Positive Psychological Well-Being And Coronary Heart Disease, Julia K. Boehm, Christopher Peterson, Mika Kivimaki, Laura D. Kubzansky

Psychology Faculty Articles and Research

Objective: Research suggests that positive psychological well-being is associated with cardiovascular health. However, much of this research uses elderly samples and has not determined the pathways by which psychological well-being influences cardiovascular disease or whether effects are similar for men and women. This study investigates the association between two aspects of well-being (emotional vitality and optimism) and coronary heart disease (CHD) in a sample of middle-aged men and women, and considers potential mediating factors.

Method: Between 1991 and 1994, well-being and coronary risk factors were assessed among 7,942 individuals without a prior cardiovascular event from the Whitehall II …

Development Of A Positive Psychology Intervention For Patients With Acute Cardiovascular Disease, Jeff C. Huffman, Carol A. Mastromauro, Julia K. Boehm, Rita Seabrook, Gregory L. Fricchione, John W. Denninger, Sonja Lyubomirsky

Psychology Faculty Articles and Research

The management of depression and other negative psychological states in cardiac patients has been a focus of multiple treatment trials, though such trials have not led to substantial improvements in cardiac outcomes. In contrast, there has been minimal focus on interventions to increase positive psychological states in cardiac patients, despite the fact that optimism and other positive states have been associated with superior cardiovascular outcomes. Our objective was to develop an 8-week, phone-based positive psychology intervention for patients hospitalized with acute cardiac disease (acute coronary syndrome or decompensated heart failure). Such an intervention would consist of positive psychology exercises adapted …

An Investigation Of Interpersonal Disruptions And Secondary Traumatic Stress Among Mental Health Therapists, Rachael Ann Robinson-Keilig

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Mental health therapists who work with victims of trauma are often exposed to vivid descriptions of traumatic events and strong emotional expressions from their clients. Research within the last fifteen years has started to explore the impact of this indirect form of trauma exposure on therapists who treat trauma clients.

The purpose of this study was to explore the prevalence of interpersonal and sexual disruptions as symptoms of secondary traumatic stress/vicarious trauma among practicing mental health therapists, to understand how various therapist characteristics predict interpersonal and sexual disruptions, and to explore the role that gender and prior trauma history play …

Neural Substrates Of Reliability-Weighted Visual-Tactile Multisensory Integration, Michael S. Beauchamp, Siavash Pasalar, Tony Ro

Publications and Research

As sensory systems deteriorate in aging or disease, the brain must relearn the appropriate weights to assign each modality during multisensory integration. Using blood-oxygen level dependent functional magnetic resonance imaging of human subjects, we tested a model for the neural mechanisms of sensory weighting, termed “weighted connections.” This model holds that the connection weights between early and late areas vary depending on the reliability of the modality, independent of the level of early sensory cortex activity. When subjects detected viewed and felt touches to the hand, a network of brain areas was active, including visual areas in lateral occipital cortex, …

Effects Of Perceived Fitness Level Of Exercise Partner On Intensity Of Exertion, Thomas G. Plante, Meghan Madden, Sonia Mann, Grace Lee

Psychology

Problem statement: Social comparison theory was used to examine if exercising with a research confederate posing as either high fit or low fit would increase the exertion in exercising. Approach: 91 college students were randomly assigned to one of three conditions: Biking alone, biking with a high fit confederate, or biking with a low fit confederate. All participants were instructed to complete 20 min of exercise at 60-70% of their maximum target heart rate. Results: Results indicated that participants in the high fit condition exercised harder than those in the low fit condition. However, no mood differences emerged between conditions. …

Latino Family Variables And Sexual Activity In Latino Adolescents, Brittany Nicole Barber

Counselor Education and Counseling Psychology Research Exchange Conference

Researchers’ focused examination of Latino adolescents’ cultural values and sexual activity has yielded questions regarding the cultural- and gender-specific attitudes and practices of these youth (Deardorff, Tschann, & Flores, 2008). Cultural values include family-related variables such as different aspects of familism, parent-adolescent communication, and parental monitoring, which have been found to decrease adolescents’ engagement in other negative activities such as aggressive behavior, (Dishion & McMahon, 1998), substance use (Estrada, Rabow, & Watts, 1982), and delinquency (Clark & Shields, 1997). Research investigating these risk behaviors has often implicated Latino adolescents’ level of assimilation to White, mainstream society as a potential risk …

Effects Of Caregiver Burden And Satisfaction On Affect Of Older End-Stage Renal Disease Patients And Their Spouses, Maureen Wilson-Genderson, Rachel A Pruchno, Francine P Cartwright

Rowan-Virtua School of Osteopathic Medicine Departmental Research

We examined the extent to which a 2-factor model of affect explains how the burdens and satisfactions experienced by caregivers influence their own well-being and that of the spouses for whom they provide care. Using data from 315 older patients with end-stage renal disease and their spouses, we extended tests of Lawton et al.'s (1991) 2-factor model both longitudinally and dyadically. Multilevel modeling analyses partially support the 2-factor model. Consistent with the model, mean caregiver burden has a stronger effect on both caregiver and patient negative affect than does mean caregiver satisfaction. Contrary to the model, mean caregiver satisfaction has …