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Articles 571 - 600 of 671
Full-Text Articles in Psychiatry and Psychology
Two Sudden And Unexpected Deaths Of Patients With Schizophrenia Associated With Intramuscular Injections Of Antipsychotics And Practice Guidelines To Limit The Use Of High Doses Of Intramuscular Antipsychotics, Nasratullah Wahidi, Katie M. Johnson, Allen Brenzel, Jose De Leon
Two Sudden And Unexpected Deaths Of Patients With Schizophrenia Associated With Intramuscular Injections Of Antipsychotics And Practice Guidelines To Limit The Use Of High Doses Of Intramuscular Antipsychotics, Nasratullah Wahidi, Katie M. Johnson, Allen Brenzel, Jose De Leon
Psychiatry Faculty Publications
Intravenous haloperidol has been associated with torsades de pointes (TdP). These two sudden deaths were probable adverse drug reactions (ADRs) following intramuscular (IM) antipsychotics. The autopsies described lack of heart pathology and were highly compatible with the possibility of TdP in the absence of risk factors other than the accumulation of antipsychotics with a high serum peak after the last injection, leading to death within hours. The first case was a 27-year-old African-American male with schizophrenia but no medical issues. His death was probably caused by repeated IM haloperidol injections of 10 mg (totaling 35 mg in 2 days). The …
The Effects Of A Trauma-Informed Care Training Program On Mental Health Professionals Knowledge, Skills, And Attitudes With The Smi, Angelina Pelletier
The Effects Of A Trauma-Informed Care Training Program On Mental Health Professionals Knowledge, Skills, And Attitudes With The Smi, Angelina Pelletier
PCOM Psychology Dissertations
Trauma has been found to be highly prevalent among individuals diagnosed with SMIs. Mental health professionals have been reported to misdiagnose or avoid addressing trauma in this population. There is a need to provide information about trauma and to foster awareness among mental health professionals who are treating individuals diagnosed with SMIs. With a TIC approach, operating from a recovery-oriented philosophy, there have been interventions created to address trauma and SMIs with the aim of developing awareness about trauma and the impact it may have on someone’s life. With these factors in mind, mental health professionals should be competent in …
Chronic Pain Causal Attributions In An Interdisciplinary Primary Care Clinic: Patient-Provider And Provider-Provider Discrepancies, Bryan Jensen
Theses and Dissertations
The purpose of the present study was to investigate the influence of pain causal attributions on patient pain-related functioning, treatment engagement, and clinical outcomes. Additionally, the impact of discordant pain causal attributions between patients and their providers as well as between interdisciplinary providers was examined. Patients rated their pain functioning and causal pain attributions during a regular clinic visit. Following the patient’s visit both the behavioral medicine provider and internal medicine resident provided ratings of similar pain-related functioning domains and causal attributions. Follow-up data were collected from the electronic medical record three months following that clinic visit. Overall, results revealed …
The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick
The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick
UROP Posters
The literature shows an inverse association between exercise and mental disorders. The aim of this study is to further elaborate on this association with regards to exercise and its relationship with anxiety and depression in a college sample. The subject group focused on seniors in the Spit for Science data set which incorporated a total of 821 students. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) to estimate the overall metabolic equivalents (MET’s) each student spent in walking, moderate, or vigorous activity levels in the previous week. Sum scores were used to measure depression and anxiety. Overall,the …
The Danger Zone: How The Dangerousness Standard In Civil Commitment Proceedings Harms People With Serious Mental Illness, Sara Gordon
Scholarly Works
Almost every American state allows civil commitment upon a finding that a person, as a result of mental illness, is gravely disabled and unable to meet their basic needs for food and shelter. Yet in spite of these statutes, most psychiatrists and courts will not commit an individual until they are found to pose a danger to themselves or others. All people have certain rights to be free from unwanted medical treatment, but for people with serious mental illness, those civil liberties are an abstraction, safeguarded for them by a system that is not otherwise ensuring access to shelter and …
Association Between Depression And Aggression In Rural Women, Laetitia Meyrueix, Gabriel Durham, Jasmine Miller, K. Bryant Smalley Phd, Psyd, Jacob C. Warren Phd
Association Between Depression And Aggression In Rural Women, Laetitia Meyrueix, Gabriel Durham, Jasmine Miller, K. Bryant Smalley Phd, Psyd, Jacob C. Warren Phd
Journal of Health Disparities Research and Practice
Rural women represent approximately 20% of women living in the United States, yet research on the specific mental health needs of rural women is limited. Given the well-recognized gender-linked disparity in depression, its correlated symptoms in women still need much investigation. While emerging notions of depression in men embrace potential symptoms related to irritability and aggression, less research has focused on the potential role of aggression in depressed women. This connection may be particularly relevant for rural women who face unique mental health stressors in comparison to their urban counterparts. The purpose of this study was to examine if aggression …
Depression With Pain Co Morbidity Effect On Quality Of Life Among Hiv Positive Patients In Uganda: A Cross Sectional Study, Shirley Moore, Martha Sajatovic
Depression With Pain Co Morbidity Effect On Quality Of Life Among Hiv Positive Patients In Uganda: A Cross Sectional Study, Shirley Moore, Martha Sajatovic
Faculty Scholarship
Background: Depression with pain comorbidity (DPC) has not been clearly defined among HIV positive patients in sub-Saharan Africa. It still remains a challenge despite many studies in Africa documenting a high prevalence of pain and depression among people living with HIV/AIDS. Both are associated with a grave impact on the health related outcomes in this pandemic. This study aimed at determining the prevalence, factors associated and effect on quality of life of DPC among HIV positive patients. Methods: In a cross-sectional survey, 345 HIV positive patients were enrolled into the study. Using a pre-tested standardised questionnaire the presence of DPC …
Knowledge, Attitudes And Perceptions Of Stroke: A Cross-Sectional Survey In Rural And Urban Uganda, Svetlana Pundik, Anthony J. Furlan, Martha Sajatovic
Knowledge, Attitudes And Perceptions Of Stroke: A Cross-Sectional Survey In Rural And Urban Uganda, Svetlana Pundik, Anthony J. Furlan, Martha Sajatovic
Faculty Scholarship
Background: Information regarding the increasing burden of non-communicable diseases such as stroke is largely unknown among the vulnerable communities. This analysis, which is part of a larger U.S. National Institute of Heath-funded Medical Education Partnership Initiative neurological disorder survey, assessed community knowledge and attitudes on stroke and stroke risk factors. Methods: A population cross-sectional survey was conducted in urban and rural Mukono, district, central Uganda. Through the systematic sampling method, data were gathered from 377 adult participants who were interviewed about selected aspects of stroke knowledge, attitudes and perception using a pretested structured questionnaire. Results: A total of 377 participants …
The Hidden Epidemic: Mental Health Epidemiology In Post-Conflict Populations And Implications For Conflict Transformation Practices, Jennifer Sato
The Hidden Epidemic: Mental Health Epidemiology In Post-Conflict Populations And Implications For Conflict Transformation Practices, Jennifer Sato
Capstone Collection
This capstone explores the ramifications of unmitigated mental health illness in conflict populations, paying special attention to refugees and migrants. The intersection between conflict and mental health is explored and analyzed in order to highlight the implications of the findings and to make recommendations to both metal health and conflict transformation practitioners. This capstone depends predominately on secondary resources and personal interviews and is informed by my own practicum experience at a refugee health center. The need to improve mental health outcomes in order to pursue conflict transformation and peace building is a key focus and is supported by the …
Asenapine For Bipolar Disorder, Thomas Scheidemantel, Irina Korobkova, Martha Sajatovic
Asenapine For Bipolar Disorder, Thomas Scheidemantel, Irina Korobkova, Martha Sajatovic
Faculty Scholarship
Asenapine (Saphris®) is an atypical antipsychotic drug which has been approved by the US Food and Drug Administration for the treatment of schizophrenia in adults, as well as the treatment of acute manic or mixed episodes of bipolar I in both adult and pediatric populations. Asenapine is a tetracyclic drug with antidopaminergic and antiserotonergic activity with a unique sublingual route of administration. In this review, we examine and summarize the available literature on the safety, efficacy, and tolerability of asenapine in the treatment of bipolar disorder (BD). Data from randomized, double-blind trials comparing asenapine to placebo or olanzapine in the …
The Effects Of Alpha Stimulation On Induced Anxiety, Nolan Thomas Hill
The Effects Of Alpha Stimulation On Induced Anxiety, Nolan Thomas Hill
Electronic Theses and Dissertations
Anxiety is defined as an emotional and physical reaction that prepares us to confront a feared stimulus. Among the many measureable changes induced by anxiety are changes in facial electromyography (EMG), heart rate (HR), and sweat gland activity (EDG). At a pathological level anxiety interferes with cognitive processes. Currently, when anxiety crosses into the pathological level, it is treated with a variety of therapies that share in their use of periods of exposure to anxiety-inducing stimuli. Several devices have been developed to alter brain activity by transcranial electrical stimulation (TCES). One such device, Alpha-Stim®, has been shown to …
Research Brief: "Impact Of Parents' Wartime Military Deployment And Injury On Young Children's Safety And Mental Health", Institute For Veterans And Military Families At Syracuse University
Research Brief: "Impact Of Parents' Wartime Military Deployment And Injury On Young Children's Safety And Mental Health", Institute For Veterans And Military Families At Syracuse University
Institute for Veterans and Military Families
This brief is about the relationship between the mental health of military children and parental deployment. In policy and practice, healthcare providers and teachers should understand the risks during the post-deployment period and the DoD should implement programs to help military families during the post-deployment period. Suggestions for future research include conducting a study over time on this topic, as well as expanding the sample to include longer and multiple deployments and various age groups of children within military families.
Knowledge And Attitudes Of Parkinson's Disease In Rural And Urban Mukono District, Uganda: A Cross-Sectional, Community-Based Study, Martha Sajatovic
Knowledge And Attitudes Of Parkinson's Disease In Rural And Urban Mukono District, Uganda: A Cross-Sectional, Community-Based Study, Martha Sajatovic
Faculty Scholarship
Background. Parkinson's disease (PD) negatively affects the quality of life. There is limited information on PD published from Africa. Lack of adequate knowledge poses a barrier in the provision of appropriate treatment and care for individuals with PD. Methods. A cross-sectional survey was conducted in urban and rural Mukono district, central Uganda. Through the systematic sampling method, data were gathered from 377 adult participants, interviewed on selected aspects of PD knowledge and attitudes. Results. Of the 377 participants, 47% were from urban settings and 68% (260/377) were women with a median age (IQR) of 34 (26-48) years. Half of the …
Behavioural Charactertics Of Patients Vulnerable For Repeated Hospitalisation, Amresh Srivastava, Coralee Berlmont, Miky Kaushal, Avinash Desouza, Robbie Campbell, Larry Stitt
Behavioural Charactertics Of Patients Vulnerable For Repeated Hospitalisation, Amresh Srivastava, Coralee Berlmont, Miky Kaushal, Avinash Desouza, Robbie Campbell, Larry Stitt
Data and Test Instruments
Background Re-hospitalization which takes place in about 30 to 50% postdischarge patienst, leads to poor outcome, increased rate of mortality and consumes more than 2/3 of budgetary allocations. Inability to identify vulnerable candidates for repeated admissions limits our options for strategic treatment. Methods In this prospective study conducted at Regional Mental Health Care ( Presently Parkwood Institute) 101 patienst ( 51 feamles, mean age 43 years), were examined using standard psychometric tools on parameters of clinical, psychopathological, suicide behaviour and resiliency for their risk and preventive characerstics. Results We assessed 101 subjects (51 females) with mean age of 42 years. …
Research Brief: "Prevalence Of Suicidality Among Hispanic And African American Veterans Following Surgery", Institute For Veterans And Military Families At Syracuse University
Research Brief: "Prevalence Of Suicidality Among Hispanic And African American Veterans Following Surgery", Institute For Veterans And Military Families At Syracuse University
Institute for Veterans and Military Families
This brief is about the likelihood of suicidal behavior and ideation among African Americans and Hispanic Americans after surgery. In policy and practice, pain medications should be prescribed after major surgery, health professionals should evaluate for both physical and psychological suffering several months after surgery, and also provide more services to the patient if necessary; the VHA should expand its suicide prevention program and tailor interventions toward cultural subgroups. Suggestions for future research include looking at prescriber and patient characteristics when prescribing pain medication, looking at the differences in post-surgery coping by race, and relying on data from veterans about …
Should Suicide Behaviour Be An Outcome Parameter For Mental Disorder, Amresh Srivastava
Should Suicide Behaviour Be An Outcome Parameter For Mental Disorder, Amresh Srivastava
Data and Test Instruments
Suicide and mental illness are closely related to each other. A high number of people who commit suicide suffer from a mental illness, and a high number of mentally ill patients exhibit suicide behavior. Suicide behavior is a significant aspect of mental illness. It is consistently observed throughout the course of illness, seen in the prodromal stage, during acute phase of remission, in residual phase and whenever illness relapses. A number of times, mental disorder improves but suicide behavior persists. 10-15% patients attempt suicide in the initial phase of an illness. More than half of the patients get hospitalized due …
Early Mortality And Functional Outcome After Acute Stroke In Uganda: Prospective Study With 30 Day Follow-Up, Martha Sajatovic
Early Mortality And Functional Outcome After Acute Stroke In Uganda: Prospective Study With 30 Day Follow-Up, Martha Sajatovic
Faculty Scholarship
Identification of early outcomes post stroke and their predictors is important in stroke management strategies. We prospectively analysed 30-day outcomes (mortality and functional ability) after stroke and their predictors among patients admitted within 7 days post event to a national referral hospital in Uganda. This was a prospective study of acute stroke patients consecutively enrolled between February and July 2014. Social demographics, clinical, laboratory, imaging characteristics, outcomes (all through 30 days), time of death were assessed using standardised questionnaires. Multiple regression was used to analyse the independent influence of factors on outcomes. Of 127 patients, 88 (69.3 %) had ischemic …
A Technology-Enabled Adherence Enhancement System For People With Bipolar Disorder: Results From A Feasibility And Patient Acceptance Analysis, Martha Sajatovic, Kristina A. Cassidy, Johnny Sams, Edna Fuentes-Casiano
A Technology-Enabled Adherence Enhancement System For People With Bipolar Disorder: Results From A Feasibility And Patient Acceptance Analysis, Martha Sajatovic, Kristina A. Cassidy, Johnny Sams, Edna Fuentes-Casiano
Faculty Scholarship
Objective: As poor medication adherence is common in bipolar disorder (BD), technology-assisted approaches may help to monitor and enhance adherence. This study evaluated preliminary feasibility, patient satisfaction and effects on adherence, BD knowledge, and BD symptoms associated with the use of a multicomponent technology-assisted adherence enhancement system. Methods: This prospective study tested the system in five BD patients over a 15-day period. System components included: 1) an automated pill cap with remote monitoring sensor; 2) a multimedia adherence enhancement program; and 3) a treatment incentive program. This study evaluated system usability, patient satisfaction and effects on adherence (Morisky scale), knowledge …
Guilty By Reason Of Insanity: Unforeseen Consequences Of California's Deinstitutionalization Policy, Jen Rushforth
Guilty By Reason Of Insanity: Unforeseen Consequences Of California's Deinstitutionalization Policy, Jen Rushforth
Themis: Research Journal of Justice Studies and Forensic Science
Beginning with the passage of the Lanterman-Petris- Short Act in 1969, deinstitutionalization in California has had a devastating effect on the mentally ill. Instead of affording the mentally ill with more rights and protections, the process of shutting down state psychiatric hospitals and impeding psychiatric care for those in need caused a cascade effect leading to an increase of homelessness and incarceration. Over the past four decades, prisons and jails in California have become the de facto state mental hospitals, with severely mentally ill individuals having nearly a four-to-one chance of ending up in jail or prison over a psychiatric …
An Investigation Of Aerobic Fitness, Perceived Quality Of Life And The Direct Effects Of Self-Determination Theory In College Students 2015, Alanna Darling
An Investigation Of Aerobic Fitness, Perceived Quality Of Life And The Direct Effects Of Self-Determination Theory In College Students 2015, Alanna Darling
Master's Theses
There have been numerous studies examining the association between physical activity, motivation and quality of life. In contrast, studies focusing on aerobic fitness and its relationship with levels of motivation and perceived quality of life are lacking. The purpose of this study was to explore the relationship between a direct measure of aerobic fitness, behavioral regulations, and perceptions of quality of life in college-aged sample. Participants included both males (n=129; 21.1±1.8 years) and females (n=89; 20.8±1.4 years) who completed the Behavioral Regulations of Exercise Questionnaire-2 sub-scores and Perceived Quality of Life (PQoL) instruments. Participants then performed the Queen’s College Step …
The Skinny On Eating Attitudes, Body Image, And The Thin-Ideal In College Women, Lyndsay N. Greene
The Skinny On Eating Attitudes, Body Image, And The Thin-Ideal In College Women, Lyndsay N. Greene
Undergraduate Theses and Capstone Projects
There is evidence of a link between body image and disordered eating among females, and some research that suggests exposure to the media exacerbates both body dissatisfaction and eating pathology. Despite these claims, little research has been done on the effects that exposure to photo-shopped images specifically has on body dissatisfaction and eating pathology. The present study sought to further understand the relationship between cognitive distortions of body image and eating attitudes and to examine the effects that exposure to the thin-ideal found in the media has on body dissatisfaction among college aged women. Eighty female college students answered questions …
Measuring Patient Experience In A Safety Net Setting: Lessons Learned, Nina Shabbat, Katy Dobbins, Sonja Seglin, Kristin Davis
Measuring Patient Experience In A Safety Net Setting: Lessons Learned, Nina Shabbat, Katy Dobbins, Sonja Seglin, Kristin Davis
Patient Experience Journal
Safety net providers have faced barriers in administering patient experience surveys due to a lack of resources and survey expertise, but this problem has received little attention in the literature. In this manuscript, we offer lessons learned from the administration of a patient experience survey at a mid-size behavioral health care agency serving a safety net population. Specifically, we discuss resource needs, methods of increasing response rate among transient populations, methods for engaging stakeholders and clinical staff in quality improvement initiatives, and considerations for responding to setbacks and challenges dynamically. We also offer insight on the effective dissemination of results …
Mental Health Disorders In Child And Adolescent Survivors Of Post-War Landmine Explosions., Mohammad Ali Hemmati, Hamid Shokoohi, Mehdi Masoumi, Shahriar Khateri, Mohammadreza Soroush, Ehsan Modirian, Mahtab Poor Zamany Nejat Kermany, Maryam Hosseini, Batool Mousavi
Mental Health Disorders In Child And Adolescent Survivors Of Post-War Landmine Explosions., Mohammad Ali Hemmati, Hamid Shokoohi, Mehdi Masoumi, Shahriar Khateri, Mohammadreza Soroush, Ehsan Modirian, Mahtab Poor Zamany Nejat Kermany, Maryam Hosseini, Batool Mousavi
Emergency Medicine Faculty Publications
BACKGROUND: To describe the mental health status of 78 child and adolescent survivors of post-war landmine explosions.
METHODS: Child and adolescent survivors of landmine explosions who were younger than 18 years old at the time of the study were identified and enrolled in this study. The mental health status of the participants was assessed by general health assessment and psychiatric examinations. Psychiatric assessment and diagnosis were undertaken using the Diagnostic and Statistical Manual for mental disorders (DSM-IV) criteria. A psychiatrist visited and interviewed each survivor and identified psychiatric disorders.
RESULTS: Seventy-eight child and adolescent survivors with a mean age of …
Evidence Of Distinctive Structural Alterations That Differentiate Adhd Boys With And Without A Comorbid Reading Disability, Dhruman Dilip Goradia
Evidence Of Distinctive Structural Alterations That Differentiate Adhd Boys With And Without A Comorbid Reading Disability, Dhruman Dilip Goradia
Wayne State University Dissertations
Attention deficit hyperactivity disorder (ADHD) and reading disability (RD) are neurodevelopmental disorders that often co-occur. Children with ADHD and co-occurring RD (ADHD/+RD) tend to show greater cognitive deficits than children with ADHD alone (ADHD/-RD). However, the extents to which comorbid RD impact structural alteration in children with ADHD have never been investigated. The overall goal of this study was to assess structural alterations in the subcortical, cortical and white matter that may differentiate ADHD/-RD from ADHD/+RD. The general hypothesis was that ADHD/+RD would show extensive alterations in regions implicated in ADHD than ADHD/-RD as well as show additional abnormalities in …
Impact Of Caregiving Role In The Quality Of Life Of Family Caregivers For Persons With Alzheimer's Disease, Supriya Sarkar
Impact Of Caregiving Role In The Quality Of Life Of Family Caregivers For Persons With Alzheimer's Disease, Supriya Sarkar
All Graduate Theses, Dissertations, and Other Capstone Projects
This study investigated quality of life of family caregivers of persons with Alzheimer's disease (AD). Caregiving is a strenuous and challenging job. Family caregivers experience poor quality of life after they take the role of caregiving which might be related to depression. Purpose of this study was to find if caregiving duration and depression has any role in affecting family caregivers' emotional, physical, and general health.
Data for this study were collected through electronic and mailed survey methods. The questionnaires completed by subjects: Medical Outcomes Study Short Form 36 (MOS-36) and Center for Epidemiologic Studies Depression Scale (CES-D). Descriptive statistics …
Impacts Of Objective And Subjective Social Inclusion On The Quality Of Life Of Individuals With Schizophrenia Spectrum Disorders And Major Depressive Disorder, Katie A. Johanning-Gray
Impacts Of Objective And Subjective Social Inclusion On The Quality Of Life Of Individuals With Schizophrenia Spectrum Disorders And Major Depressive Disorder, Katie A. Johanning-Gray
PCOM Psychology Dissertations
Increased social inclusion and enhanced quality of life for individuals with severe mental illnesses (SMIs) are goals of the recovery movement. The present study examined the differences in reported subjective social inclusion (SubSI) and objective social inclusion (ObjSI) between individuals diagnosed with schizophrenia spectrum disorders (SSDs) and those diagnosed with Major Depressive Disorder (MDD). Furthermore, the amount of variance in quality of life (QOL) which can be predicted by type of diagnosis, SSDs or MDD, symptom severity, and SubSI and ObjSi was determined. An archival data set was used. Participants were 337 individuals whose primary diagnosis was an SSD or …
Adhd Children And Mental Health Service Use: Maternal Determinants, Katarina Krizova
Adhd Children And Mental Health Service Use: Maternal Determinants, Katarina Krizova
Theses and Dissertations--Family Sciences
The current study investigated maternal determinants of mental health service use, namely, individual child therapy, among preadolescent children diagnosed with ADHD. The Behavioral Model of Health Care Utilization (Andersen, 2008) was used as a theoretical framework for the study. Data from the last three rounds of ECLS-K dataset were employed to test a longitudinal model using Bayesian analysis. Socio-demographic variables and maternal mental health were tested as exogenous variables and mother-child relationship variables, discipline variables, and perceived maternal concern about child’s overall behavior and child’s emotional symptoms were tested as intervening variables. Results showed that only maternal mental health remained …
Trauma In Patients With Serious Mental Illness: The Acceptability And Impact Of A Brief Psychoeducational Intervention For Trauma In The General Acute Inpatient Psychiatric Setting, Kevin E. A. Giangrasso
Trauma In Patients With Serious Mental Illness: The Acceptability And Impact Of A Brief Psychoeducational Intervention For Trauma In The General Acute Inpatient Psychiatric Setting, Kevin E. A. Giangrasso
PCOM Psychology Dissertations
Prevalence rates of posttraumatic stress disorder (PTSD) for individuals with serious mental illnesses (SMIs) are high, with an estimated 49% to 100% being exposed to potentially traumatic events. The consequences of these disorders are serious and lasting, with PTSD being the costliest of mental health disorders. At the same time, established evidence-based treatments for PTSD are often not feasible in treatment settings utilized by individuals with SMIs, namely the general acute inpatient psychiatric hospital. Psychoeducational approaches have been incorporated as a component of evidence-based interventions for trauma and have been feasibly implemented in the general acute inpatient psychiatric hospital. The …
The Effectiveness Of A Computer-Assisted, Cognitive-Behavior Program For Treating Anxiety Symptoms In Children With Autism Spectrum Disorder, Jennifer A. Zabel
The Effectiveness Of A Computer-Assisted, Cognitive-Behavior Program For Treating Anxiety Symptoms In Children With Autism Spectrum Disorder, Jennifer A. Zabel
PCOM Psychology Dissertations
Autism Spectrum Disorder (ASD) is a complex and multifaceted, neurodevelopmental disorder that severely impacts children and families across a variety of settings. Prevalence rates of ASD are continuing to increase rapidly, with sizeable intervention and treatment costs placed on families and society. Further complicating the matter, many individuals with ASD also evidence co-occurring anxiety symptoms or disorders and tend to be at a higher risk for developing such problems when compared to other clinical populations or typically developing children. This study investigated the effectiveness of a computer-assisted CBT program, Camp Cope-A-Lot (CCAL), in regards to reducing anxiety symptoms in four …
Chronic Behavioral And Cognitive Deficits In A Rat Survival Model Of Organophosphate Toxicity, Beverly Huang
Chronic Behavioral And Cognitive Deficits In A Rat Survival Model Of Organophosphate Toxicity, Beverly Huang
Theses and Dissertations
Organophosphates (OPs) are a major class of pesticides and nerve agents that elicit acute toxicity by inhibiting acetylcholinesterase (AChE), the enzyme responsible for the degradation of the neurotransmitter acetylcholine in the central and peripheral nervous systems. Acetylcholine accumulation following extensive AChE inhibition leads to an acute cholinergic syndrome characterized by autonomic dysfunction, involuntary movements, muscle fasciculations, respiratory distress, and seizures. Despite their classification as moderate to highly toxic, OP pesticides are the most widely used class of insecticides in the U.S., and are even more commonly used worldwide. Additionally, there is a growing concern that OP nerve agents could be …