Natural Products Chemistry and Pharmacognosy Commons^™

Antimicrobial And Cytotoxic Activities Of Ascidian Species Collected From Egyptian Coasts, Amany Metwally, Sarah Ali Shalaby, Tarek Ahmed Temraz, Mohammed Ismail Ahmed

Bulletin of Faculty of Pharmacy Cairo University

Discovering novel drugs for curing cancer and infectious diseases is the prime interest of several research areas now. Marine sessile invertebrates have produced secondary metabolites, a lot of which are utilized as novel pharmaceutical agents with diverse effects whether anti-cancer or anti-microbial. Ascidians are marine sessile animals (phylum: Chordata, class: Ascidiacea). Various anti-cancer, anti-viral, and anti-bacterial components are obtained from different bioactive compounds belonging to ascidian species and are in different stages of clinical trials. In this study, five ascidian species which are Polyclinum constellatum, Botryllus eilatensis, Didemnum sp., Symplegma rubra, and Styela canopus were collected from two coastal sites …