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Full-Text Articles in Natural Products Chemistry and Pharmacognosy
Psychedelics Can Save: The Scientific And Social Case For Rescheduling Psychedelic Compounds, Galen M. Fader
Psychedelics Can Save: The Scientific And Social Case For Rescheduling Psychedelic Compounds, Galen M. Fader
Chancellor’s Honors Program Projects
No abstract provided.
Characterization Of G-Protein Coupled Receptors In Pain, Depression And Anxiety, Neil Lax
Characterization Of G-Protein Coupled Receptors In Pain, Depression And Anxiety, Neil Lax
Electronic Theses and Dissertations
Chronic pain and major depressive disorder are widespread conditions in the world. Interestingly, these conditions often occur comorbidly, with each individual disease amplifying the symptoms of the other. A significant amount of preclinical research in pain and depression focuses on G-protein coupled receptors (GPCRs), implying that GPCRs may be useful in treating this comorbidity. Our efforts have sought to characterize several poorly understood GPCRs, including the serotonin receptor subtypes 2C and 7 (5-HT2CR and 5-HT7R) and metabotropic glutamate receptor 5 (mGluR5), along with more well-known GPCRs such as the mu opioid receptor (MOR), and the role that they play in …