Open Access. Powered by Scholars. Published by Universities.®
Pharmacy and Pharmaceutical Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Publication Type
Articles 1 - 3 of 3
Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Understanding The Impact Of Bcrp And Pgp Efflux Transporters On The Disposition Of Their Endogenous, Xenobiotic And Dietary Substrates, Samit Ganguly
Understanding The Impact Of Bcrp And Pgp Efflux Transporters On The Disposition Of Their Endogenous, Xenobiotic And Dietary Substrates, Samit Ganguly
Theses and Dissertations (ETD)
Breast Cancer Resistant Protein (BCRP) and P-glycoprotein (PGP) are membrane-bound efflux transporters that transport multiple chemical classes of compounds and act as barriers to tissue permeability, thereby regulating tissue exposure of their substrates. The role of these transporters in therapeutic resistance of their xenobiotic substrates due to their expression and efflux function at target organs/tissues, especially in brain and intestine, is well established, which has fueled investigation toward identification of their inhibitors. Multiple clinically used drugs and dietary chemicals have been reported to inhibit these transporters and potentially increase the exposure of concomitantly administered BCRP and/or PGP substrates, which might …
Ketamine Dosing For Sedation In Mechanically Ventilated Patients, Zsanett Kormanyos Pharmd
Ketamine Dosing For Sedation In Mechanically Ventilated Patients, Zsanett Kormanyos Pharmd
Pharmacy Residency
Presentation given at Great Lakes Pharmacy Residency Conference 2018
Impact Of Clinical Guideline Implementation Of Adult Ketamine Dosing In The Emergency Department, Julia Dickman Pharmd
Impact Of Clinical Guideline Implementation Of Adult Ketamine Dosing In The Emergency Department, Julia Dickman Pharmd
Pharmacy Residency
Presentation given at Great Lakes Pharmacy Residency Conference 2018