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Multicompartment Hard Capsule With Control Release Properties, George Digenis, Dagmar Noskova
Multicompartment Hard Capsule With Control Release Properties, George Digenis, Dagmar Noskova
Pharmaceutical Sciences Faculty Patents
The present invention relates to a hard capsule made from a material such as gelatin, starch or a hydrophilic polymer. The capsule of the present invention is formulated into a delivery system which incorporates pharmacologically active components in three or more distinct compartments. When three compartments are utilized in the capsule, the outer compartment incorporates a drug and excipients into a layer which coats the outer part of the capsule. This layer represents the rapid release portion of the delivery system. The intermediate compartment comprises a powder formulation comprised of a drug and excipients which represents the intermediary speed release …