Pharmacy and Pharmaceutical Sciences Commons^™

The Clinical Pharmacy Program In A Community Hospital Setting : An Integral Part Of The Educational Process, Franklin D. Kamian

University of the Pacific Theses and Dissertations

The intent of this work is to emphasize that the concept of clinical pharmacy is no longer an innovation or an educational experiment, but rather is a reality which requires national recognition, professional as well as legislative support, and clearly planned educational preparation.

Characterization Of The Physical Properties And The Bioavailability Of Phenobarbital Tablets, Usp, 100 Mg, Mario F. Sylvestri

University of the Pacific Theses and Dissertations

The Food, Drug, and Cosmetic Act of 1938 required a producer of a new drug to substantiate the safety of the drug product when used as recommended; however, the introduction of the Kefauver-Harris Amendments of 1962 considerably strengthened this act. These amendments intensified the controls on quality, labeling, and safety, while adding a new requirement that all NDA's should be able to present substantial evidence of the effectiveness of the drug product for its indicated use of uses (4). The procedure used to determine the efficacy of a drug included identification of the product, copies of the labeling, and a …

Insulin Adsorption To Intravenous Delivery Systems, Michael Joseph Zarcone

University of the Pacific Theses and Dissertations

Lack of quantitative adsorption data makes it difficult for a physician to determine the actual amount of insulin received by a patient against the amount added to the intravenous infusion system. This project was therefore initiated to determine quantitatively the extent of adsorption that would occur in a clinical setting.

In order to achieve the above aim, varying amounts of carrier insulin containing I-labeled insulin were added to the intravenous infusion delivery system. Using the most commonly utilized mode of delivery and flow rate the tagged insulin solution was allowed to flow through the intravenous delivery system. Both the amount …