Open Access. Powered by Scholars. Published by Universities.®

Pharmacy and Pharmaceutical Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Richard B. Philp

Selected Works

2007

Drug interactions

Articles 1 - 1 of 1

Full-Text Articles in Pharmacy and Pharmaceutical Sciences

Risks Of Herbal Remedies: More Of The Bad And The Ugly, Richard Philp Feb 2007

Risks Of Herbal Remedies: More Of The Bad And The Ugly, Richard Philp

Richard B. Philp

The widespread and increasing use of herbal remedies has increased the risk, and the documentation, of adverse effects. This paper describes some of these that have occurred since 2004. Cases are discussed in which herbal remedies (St. John’s wort, echinacea, grapefruit juice) have altered the metabolism of prescription drugs. Others have interfered with diagnostic laboratory tests (Chan Su, Dan Shen) or caused pseudoaldosteronism due to their (unidentified) content of glycyerrhizin. Aristolochia spp. have caused nephropathy. Hypersensitivity reactions (spice ginger and others), increased sensitivity to ultraviolet therapy (PUVA) (St. John’s wort) have been reported and the consumption of blue cohosh by …