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Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Synthesis And Evaluation Of The Diarylthiourea Analogs As Novel Anti-Cancer Agents, Shengquan Liu, Maggie C. Louie, Vanishree Rajagopalan, Guangyan Zhou, Esmerelda Ponce, Tran Nguyen, Linda Green
Synthesis And Evaluation Of The Diarylthiourea Analogs As Novel Anti-Cancer Agents, Shengquan Liu, Maggie C. Louie, Vanishree Rajagopalan, Guangyan Zhou, Esmerelda Ponce, Tran Nguyen, Linda Green
Faculty Publications & Research of the TUC College of Osteopathic Medicine
No abstract provided.
Sodium Glucose Co-Transporter 2 Inhibitors In The Treatment Of Type 2 Diabetes Mellitus, Eden Miller, Jay H. Shubrook
Sodium Glucose Co-Transporter 2 Inhibitors In The Treatment Of Type 2 Diabetes Mellitus, Eden Miller, Jay H. Shubrook
Faculty Publications & Research of the TUC College of Osteopathic Medicine
Type 2 diabetes mellitus (T2DM) is a chronic, progressive disease, control of which typically requires multiple therapies. Current guidelines suggest that, in addition to improving glycemic control, antihyperglycemic therapy should be chosen on the basis of its effects on body weight and the risk of hypoglycemia. The newest class of oral antihyperglycemic agents, the sodium glucose cotransporter 2 (SGLT2) inhibitors, reduces renal glucose reabsorption and increases urinary glucose excretion via an insulin-independent mechanism of action. SGLT2 inhibitors have been shown to improve glycemic control and to reduce body weight and systolic blood pressure, and their use is associated with a …