Pharmacy and Pharmaceutical Sciences Commons^™

Release Of Salicylic Acid From Lanolin Alcohol-Ethyl Cellulose Films, Arshad Rahim Khan

University of the Pacific Theses and Dissertations

In the present study lanolin alcohol films were investigated as potential drug delivery systems for the controlled release of salicylic acid. A series of experiments were conducted in vitro to study the release of salicylic acid from these films. The effect of changes in film composition and stirrer speed on drug release were examined. Seven film compositions with varying proportions of lanolin alcohol and ethyl cellulose were prepared over the ethyl cellulose concentrations of 0-30% w/w, while keeping the drug concentration at 2.5% w/w. The release data obtained in this study were examined by the Q vs ¹_/2 relationship …