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Full-Text Articles in Pharmacy and Pharmaceutical Sciences

Data For "Subtype-Selective Positive Modulation Of Sk Channels Depends On The Ha/Hb Helices", Miao Zhang, Meng Cui Mar 2021

Data For "Subtype-Selective Positive Modulation Of Sk Channels Depends On The Ha/Hb Helices", Miao Zhang, Meng Cui

Pharmacy Faculty Data Sets

In the activated state of small-conductance Ca2+-activated potassium (SK) channels, calmodulin interacts with the HA/HB helices and the S4-S5 linker. CyPPA potentiates SK2a and SK3 channel activity but not the SK1 and IK subtypes. Here, we report that the subtype-selectivity of CyPPA relies on the HA/HB helices. Mutating residues in the HA (V420) and HB (K467) helices of SK2a channels to their equivalent residues in IK channels diminished the potency of CyPPA. CyPPA elicited prominent responses on mutant IK channels with an arginine residue in the HB helix substituted for its equivalent lysine residue in the SK2a channels …


Equity For All: Providing Accessible Healthcare For Patients Living With Disabilities, Michelle L. Blakely, Sharon E. Connor, Jennifer Ko Jan 2021

Equity For All: Providing Accessible Healthcare For Patients Living With Disabilities, Michelle L. Blakely, Sharon E. Connor, Jennifer Ko

Pharmacy Faculty Books and Book Chapters

At the end of this activity, students will be able to:

  • Identify relevant resources to assist patients living with disabilities
  • Recommend appropriate patient-specific resources to minimize barriers to health
  • Identify strategies to enhance the healthcare experience of patients living with disabilities
  • Describe the policies that currently exist to enhance care for patients living with disabilities


Let Your Pharmacist Be Your Guide: Navigating Barriers To Pharmaceutical Access, Jennifer Ko, Miranda Steinkopf, Sharon E. Connor Jan 2021

Let Your Pharmacist Be Your Guide: Navigating Barriers To Pharmaceutical Access, Jennifer Ko, Miranda Steinkopf, Sharon E. Connor

Pharmacy Faculty Books and Book Chapters

At the end of this case, students will be able to: • Describe policy, organizational, and individual factors that contribute to barriers to accessing medications and pharmaceutical care • Identify resources to improve access to affordable medications for uninsured and underinsured patients • Recommend appropriate resources for obtaining affordable medications


Digging Deeper: Improving Health Communication With Patients, Jennifer Ko, Miranda Steinkopf, Abby A. Kahaleh, Sharon Connor Jan 2021

Digging Deeper: Improving Health Communication With Patients, Jennifer Ko, Miranda Steinkopf, Abby A. Kahaleh, Sharon Connor

Pharmacy Faculty Books and Book Chapters

At the end of this activity, students will be able to:

  • Identify five theories and models that can be used to facilitate the patient-provider health communication process
  • Describe opportunities to optimize communication with patients in healthcare settings
  • Apply health communication theories within patient care, providing specific approaches and language to utilize