Open Access. Powered by Scholars. Published by Universities.®
Pharmacy and Pharmaceutical Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Institution
- Publication
- Publication Type
Articles 1 - 4 of 4
Full-Text Articles in Pharmacy and Pharmaceutical Sciences
Enzim Papain: Aspek Green Chemistry Pada Reaksi Knoevenagel, Laurentius Haryanto, Antonius Herry Cahyana
Enzim Papain: Aspek Green Chemistry Pada Reaksi Knoevenagel, Laurentius Haryanto, Antonius Herry Cahyana
Pharmaceutical Sciences and Research
Green chemistry aspect is the chemical approach that has been studied in the past two decade. One of the principles is the development of green synthesis process that is friendly for the environment. This research showed that papain can be used as catalyst for Knoevenagel reaction with 3 kinds of substituted-benzaldehyde and malononitrile as substrates in aqueous medium. The best reaction condition with 80% yield was reached by utilizing of 25 mg papain/mmol substrate. Reaction was conducted at ambient temperature and pressure for 30 min. Products were as yellowish to yellow needle crystals and successfully characterized by melting point, UV-Vis, …
Losio Antioksidan Buah Naga Merah (Hylocereus Polyrhizusbritton And Rose), Amanda Angelina Sinaga, Sri Luliana, Andhi Fahrurroji
Losio Antioksidan Buah Naga Merah (Hylocereus Polyrhizusbritton And Rose), Amanda Angelina Sinaga, Sri Luliana, Andhi Fahrurroji
Pharmaceutical Sciences and Research
Hylocereus polyrhizus Britton and Rose (Red dragon fruit) has been shown to have antioxidant activity which contains vitamin C, polyphenol, and flavonoid. This research was aimed to investigate antioxidant activity from H. polyrhizus in form of lotion. Lotion were made with 5 concentration from H. polyrhizus methanol extract were 0.04, 0.08, 0.16, 0.32 and 0.64%. Lotion antioxidant activity was measured using DPPH method. The result showed that H. polyrhizus methanol extract had antioxidant activity with inhibition concentration were 19.99±0.33; 25.01±0.08; 39.14±0.04; 66.69±0.12 and 83.37±0.05. The result showed significant differences on antioxidant activity. The physical stability observation of five formula with …
Aktivitas Antioksidan Ekstrak, Fraksi Dan Golongan Senyawakimia Daun Premna Oblongata Miq, Katrin Katrin, Atika Bendra
Aktivitas Antioksidan Ekstrak, Fraksi Dan Golongan Senyawakimia Daun Premna Oblongata Miq, Katrin Katrin, Atika Bendra
Pharmaceutical Sciences and Research
Indonesia has many kinds of plants which can be used as natural antioxidant sources. This study was focused on antioxidant activity of Cincau Perdu leaves extract (Premna oblongata Miq.) using 1-Diphenyl-2-picrylhydrazyl (DPPH) methods. P. oblongata leaves was extracted using n-hexane, ethylacetate and methanol. It was found that methanol extract has the highest activity with IC50 value 20.01 μg/mL. The extract with highest antioxidant activity were fractionated with accelerated column chromatography and were earned 6 combination fractions. The antioxidant activity of each combination fractions were tested by DPPH methods. Fraction-5 showed the highest activity as antioxidant with IC50 23.51 μg/mL. The …
Evaluating Antioxidant Activity Of Selected Plant Species Native To Cedarville, Ohio, Daniel A. Benson, Alexander P. Treide, David Woodfield, Joshua A. Sitler, Denise S. Simpson, Robert L. Paris
Evaluating Antioxidant Activity Of Selected Plant Species Native To Cedarville, Ohio, Daniel A. Benson, Alexander P. Treide, David Woodfield, Joshua A. Sitler, Denise S. Simpson, Robert L. Paris
The Research and Scholarship Symposium (2013-2019)
Over the past several decades, there has been an increase in the number of synthetic drug molecules developed and utilized to treat various conditions. Although these synthetic drugs have proven useful, there has been growing public concern regarding the potentially negative long-term effects of synthetic agents on the body. As a result, there has been an increased interest in identifying and utilizing plant extracts and purified compounds since they are perceived to be a more natural alternative to synthetic drugs. The goal of this study was to evaluate the specific antioxidant properties of alsike clover Trifolum hybridum when produced under …