Open Access. Powered by Scholars. Published by Universities.®
Pharmacy and Pharmaceutical Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Abortion (1)
- Analytical Methods (1)
- Antibiotic resistance (1)
- Antibody (1)
- Antigen (1)
-
- Autodock (1)
- Autodock vina (1)
- Autoimmune (1)
- Avogadro (1)
- Bacterial infection (1)
- Birth Control (1)
- Blocking antibodies (1)
- Blocking antigens (1)
- Cell biology (1)
- Chemical Gradients (1)
- Chimerax (1)
- Chromatography (1)
- Contraception (1)
- Controversial (1)
- Drug Analysis (1)
- Drug Development (1)
- Estrogen (1)
- Ferroptosis (1)
- HPV vaccine (1)
- High-Performance Liquid Chromatography (1)
- Hormones (1)
- In silico (1)
- MCTD (1)
- Mechanisms of Action (1)
- Methods (1)
Articles 1 - 5 of 5
Full-Text Articles in Pharmacy and Pharmaceutical Sciences
The Implications Of Ferroptosis In Antibiotic Resistance, Marysol Hohl
The Implications Of Ferroptosis In Antibiotic Resistance, Marysol Hohl
Senior Honors Theses
Bacterial infections in the United States are becoming increasingly resistant to existing antibiotic treatments. Due to projected increases in resistance and the recent decrease in novel antibacterials, experts have determined that the United States is in the “post-antibiotic era.” The scientific community has failed to resolve resistance despite the continual discovery of new antibiotic compounds. In the past decade, a novel form of cell death called ferroptosis has been implicated in antibiotic treatment by employing the use of nanotechnology. This literature review will describe the problem of bacterial resistance and demonstrate how current research is pioneering a new age of …
The Application Of Continuous Stationary Phase Gradients To High-Performance Liquid Chromatography And Its Potential To Improve Pharmacological Research, Hannah Klose
Senior Honors Theses
The separation of mixtures into different components is integral to experimentation and analysis in a multitude of fields. Chromatography is one of the most popular, well-developed, and well-studied methods used to examine the makeup of a mixture. Thus, the improvement of chromatographic procedures directly benefits research across many scientific disciplines. The application of a continuous stationary phase gradient to High-Performance Liquid Chromatography (HPLC) methods has been proposed to improve the separation of complex mixtures that are difficult to achieve with existing separation techniques. By incorporating a gradient stationary phase, analysts will create a more selective mode of separation to improve …
A Proposed Treatment Of Mixed Connective Tissue Disease By Competitive Inhibition Of Autoantibodies, Thomas Russell
A Proposed Treatment Of Mixed Connective Tissue Disease By Competitive Inhibition Of Autoantibodies, Thomas Russell
Senior Honors Theses
Mixed Connective Tissue Disease is an autoimmune disease characterized by Raynaud’s phenomenon and arthritis among other symptoms. It is primarily caused by antibodies that target the U1-RNP 70K peptide. The treatment proposed in this paper uses competitive inhibition to prevent the binding of the anti-U1-RNP 70K antibodies with the U1-RNP 70K peptide. A method for testing the designed treatment in silico is proposed using AutoDock Vina docking software.
Contraceptive Methods In The United States: The Question Of Abortive Mechanisms, Tara Ferenczy
Contraceptive Methods In The United States: The Question Of Abortive Mechanisms, Tara Ferenczy
Senior Honors Theses
This thesis reviews the many methods of contraception available in the United States. Although society’s understanding of women’s health has become a major topic, there is still a significant deficit of information regarding how the accessible methods affect women’s bodies, specifically reproductive tissue. The thesis analyzes numerous contraceptive options focusing specifically on the mechanisms of action to determine whether options have abortifacient properties so that readers may develop educated opinions regarding medical and ethical uses. Information involving strengths and limitations of each technique and the effects on both the female body and the reproductive material assist in understanding the process …
Vaccines In Current Culture: The Hpv Vaccine Controversy, Alyssa Johnston
Vaccines In Current Culture: The Hpv Vaccine Controversy, Alyssa Johnston
Senior Honors Theses
The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care. However, the fear of risks related to vaccines has been partially responsible for the decisions of many parents to delay or avoid vaccinating their children. The human papilloma virus (HPV) vaccine specifically is one of the most controversial vaccines in current culture due to reports of new onset or exacerbation of autoimmune diseases, infertility, and even death following its administration. This review synthesizes information regarding the relevance and safety of the HPV vaccine, as well …