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Alternative Reaction Pathways To Metformin Hydrochloride, Mohammed S. Suleiman, Stephen A. Reeves, Jorge E. Gatica
Alternative Reaction Pathways To Metformin Hydrochloride, Mohammed S. Suleiman, Stephen A. Reeves, Jorge E. Gatica
Undergraduate Research Posters 2014
Metformin Hydrochloride is an important pharmaceutical used for the treatment of type 2 diabetes. The current manufacturing of this product involves a well-known and proven process. The process includes the dissolution and reaction, followed by the precipitation of Metformin Hydrochloride. Although reliable and effective, the current process relies on the use of a solvent; which later needs to be eliminated from the precipitates. The purpose of this project is the investigation of an alternative reaction pathway which will avoid the use of solvents and simplify the final purification stage. The anticipated benefits include reduced costs for the processing and a …