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Full-Text Articles in Pharmacy and Pharmaceutical Sciences
The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples, Qamar Alshammari
The Use Of Spectral Imaging To Reveal Inorganics And Organics Identity In The Biological Samples, Qamar Alshammari
Pharmaceutical Sciences (PhD) Dissertations
The wavelength is used to identify the exact location and quantify the number of molecules in the spectral imaging system. It aids in identifying materials and studying their quantities by examining how they interact with light. A traditional spectrometer provides spectrum information of chemical compounds, while standard imaging provides the intensity at each pixel of the image. Spectral imaging (SI) combines these two aspects by equipping intensity and spectral data for each pixel. In biomedical research, it is important to assess the inorganics/organics molecules to understand drug activity, cellular toxicity, and distribution. Using the microscopy technique, we found for the …
Characterization Of The Growth Factor Receptor Network Oncogenes In Lung Cancer, Ashley Duche
Characterization Of The Growth Factor Receptor Network Oncogenes In Lung Cancer, Ashley Duche
Pharmaceutical Sciences (MS) Theses
Lung cancer remains the leading cause of cancer related deaths worldwide, reportedly contributing to 1.8 million of the 10.0 million mortalities documented in the year 2020. Although advancements have been made in therapeutics and diagnostic methods, formulation of effective treatments and development of drug resistance continues to be a challenge. These challenges arise from our lack of understanding of intricate signaling pathways, such as the Growth Factor Receptor Network (GFRN), which contributes to complex lung tumor heterogeneity allowing for drug resistance development. In this study, gene expression signatures of six GFRN oncogenes overexpressed in human mammary epithelial cells (HMECs) were …
Viral Factors Influencing Early Infection Events During Ex-Vivo Kshv Infection, Ramina Nabiee
Viral Factors Influencing Early Infection Events During Ex-Vivo Kshv Infection, Ramina Nabiee
Pharmaceutical Sciences (PhD) Dissertations
The enigma of Kaposi Sarcoma Herpes Virus infection, and its persistence despite a quarter century of research on the virus, has given rise to an immediate need for addressing fundamental questions about basic immunology and virology knowledge regarding this virus. Kaposi Sarcoma Herpes Virus (KSHV), also known as Human Herpesvirus 8 (HHV8), is the etiological agent of Kaposi Sarcoma (KS) and other lymphoproliferative cancers, such as Multicentric Castleman’s Disease (MCD), Primary Effusion Lymphoma (PEL), and a newly discovered rare disease called KSHV Inflammatory Cytokines Syndrome (KICS). Epidemic KS, also known as AIDS-KS, is the most common cancer in untreated HIV …