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Articles 1 - 30 of 83
Full-Text Articles in Other Medicine and Health Sciences
Implementation Of An Opioid Risk Assessment Tool, Stacey Cuomo
Implementation Of An Opioid Risk Assessment Tool, Stacey Cuomo
Seton Hall University DNP Final Projects
The increased prevalence of opioid use in society has led to an increase in surgical patients with a history of such use. Patients who use or are addicted to opioids have different tolerances and responses to anesthesia than non-opioid users, and will require different care than non-users both pre- and post-operatively. The means to identify this population prior to a surgical procedure is needed as a way to organize, plan and manage patient care during the perioperative period. An Opioid Risk Assessment Tool (ORAT) was used as a way to streamline the process of identifying these patients. This paper addresses …
A Gut Pathobiont Synergizes With The Microbiota To Instigate Inflammatory Disease Marked By Immunoreactivity Against Other Symbionts But Not Itself, João Carlos Gomes-Neto, Hatem Kittana, Sara Mantz, Rafael R. Segura Munoz, Robert J. Schmaltz, Laure B. Bindels, Jennifer L. Clarke, Jesse M. Hostetter, Andrew K. Benson, Jens Walter, Amanda Ramer-Tait
A Gut Pathobiont Synergizes With The Microbiota To Instigate Inflammatory Disease Marked By Immunoreactivity Against Other Symbionts But Not Itself, João Carlos Gomes-Neto, Hatem Kittana, Sara Mantz, Rafael R. Segura Munoz, Robert J. Schmaltz, Laure B. Bindels, Jennifer L. Clarke, Jesse M. Hostetter, Andrew K. Benson, Jens Walter, Amanda Ramer-Tait
Department of Food Science and Technology: Faculty Publications
Inflammatory bowel diseases (IBD) are likely driven by aberrant immune responses directed against the resident microbiota. Although IBD is commonly associated with a dysbiotic microbiota enriched in putative pathobionts, the etiological agents of IBD remain unknown. Using a pathobiont-induced intestinal inflammation model and a defined bacterial community, we provide new insights into the immune-microbiota interactions during disease. In this model system, the pathobiont Helicobacter bilis instigates disease following sub-pathological dextran sulfate sodium treatment. We show that H. bilis causes mild inflammation in mono-associated mice, but severe disease in the presence of a microbiota, demonstrating synergy between the pathobiont and microbiota …
Using Social Narratives To Improve The Healthcare Experiences Of Children Diagnosed With Autism Spectrum Disorder, Margaret Spindel
Using Social Narratives To Improve The Healthcare Experiences Of Children Diagnosed With Autism Spectrum Disorder, Margaret Spindel
Senior Honors Projects, 2010-2019
Children with Autism Spectrum Disorder (ASD) often experience significant emotional stress when they visit a healthcare provider. The focus of this research project was to explore the use of social narratives to help reduce stress associated with this environment. Social narratives are short stories designed to walk a child through a potential situation that they will encounter, that they may not be familiar with, or that they are not currently handling properly. As part of an initial literature review, evidence for the need for additional intervention in the healthcare setting for children with ASD was established. Continuing literature review then …
Next Generation Sequencing Technologies For Real-Time Genotyping And Targeted Sequencing For Precision Medicine, Priyanka Rawat
Next Generation Sequencing Technologies For Real-Time Genotyping And Targeted Sequencing For Precision Medicine, Priyanka Rawat
Biomedical Engineering ETDs
Astounding success of Human genome project and accelerating success of sequencing technologies have enabled $ 1000 genome goals possible. But, this is still far-fetched from the reach of many resource refrained populations with high genetic variations causing lethal genetic diseases. Based on present technology principles, I have developed prototypes for affordable, scalable and customizable point-of-care genotyping and targeted sequencing. Ion-sensitive field effect transistors with novel read-out and signal amplification techniques are used for laying foundation of possible ISFET based allele-arrays. Sequencing-by-synthesis based full-fledge sequencer is made with novel immobilization, flow-cell and data acquisition methods for massive sequenciing.
A Novel Model Of “Remedy And Elimination Of Tuberculosis”, Akanksha Mishra
A Novel Model Of “Remedy And Elimination Of Tuberculosis”, Akanksha Mishra
Master's Theses
Tuberculosis (TB), is one of the top ten causes of death worldwide. TB is commonly linked to poverty and creates poverty as it is the single largest cause of death in the 15-49-year-old age group in South-East Asia (WHO, 2017). It is also linked to the HIV population, and its leading cause of death. TB is effected by socio-economic factors, cultural factors, and health policy. My goal of this dissertation is to identify systematic approaches that shall support the mission set by World Health Organization (WHO): to eliminate TB globally by the year 2050. Measures might include addressing social barriers …
Improving Transitions In Care For People With Dementia: The Cared Tool, Yuwen Deng, Jamie Bisset, Silk Lim, Maryssa Edwards
Improving Transitions In Care For People With Dementia: The Cared Tool, Yuwen Deng, Jamie Bisset, Silk Lim, Maryssa Edwards
Community Engaged Learning Final Projects
Transitions in Care are challenging for people with dementia due to impairments in communication and disorientation from being in a foreign environment. Transitions in care have lead to incidents of unnecessary physical and chemical restraints of this vulnerable population. To investigate how to optimize care transitions, qualitative descriptive information was collected through three personal interviews to gain a broader understanding of mechanisms of care transitions in London, ON. After conducting interviews and literature review, the CARED Tool was developed. The CARED Tool promotes social inclusion of patients with dementia through recognizing that people with dementia have complex needs, thereby allowing …
Subanesthetic Ketamine For Postoperative Analgesia: An Evidenced-Based Project, Jeremy Vance
Subanesthetic Ketamine For Postoperative Analgesia: An Evidenced-Based Project, Jeremy Vance
Doctoral Projects
Roughly 100 million surgical procedures are performed in the United States (U.S.) each year and more than 80% of these patients experience acute postoperative pain. Pain costs the U.S. an estimated $560 to $635 billion annually and is a significant contributor to national rates of mortality, morbidity, and disability. Despite these findings, patients continue to receive suboptimal postoperative pain relief.
The adjunct administration of subanesthetic ketamine is opioid-sparing and can improve the effectiveness of a multimodal pain management approach. This project used an exploratory descriptive design to examine how an evidence-based presentation impacted the clinical practice of certified registered nurse …
Alumni Journal - Volume 88, Number 3, Loma Linda University School Of Medicine
Alumni Journal - Volume 88, Number 3, Loma Linda University School Of Medicine
Alumni Journal, School of Medicine
Features
10 | A Letter to Alumni
12 | The Alumni Association’s Historical Ties to Research
13 | The Opera Singer
15 | Interview: It All Began with a Bald Mouse, Gerald G. Krueger ’66
18 | Graduation 2017
32 | The Art of Unconventional Connections
34 | A Balancing Act
36 | When I Am Not Rewarded
Departments
2 | From the Editor
4 | From the President
6 | From the Vice Dean
7 | The Student Fund
8 | School of Medicine News
38 | Placement and Classified Ads
39 | Alumni News
40 | In Memoriam …
A Quality Improvement Initiative To Increase Statin Therapy Adherence Among Patients With Diabetes Aged 65 Years And Older, Kelly Nunemaker
A Quality Improvement Initiative To Increase Statin Therapy Adherence Among Patients With Diabetes Aged 65 Years And Older, Kelly Nunemaker
Doctor of Nursing Practice
The purpose of this project was to improve statin therapy adherence among diabetic patients aged 65 and older treated at a small family practice clinic in western San Antonio. Additionally, the project aimed to decrease LDL cholesterol (LDL-C) levels in this patient population as recommended to 70 mg/dl or less. Diabetic patients are more likely to die from a cardiac event than patients without diabetes. Statin therapy is an important factor in lowering cholesterol, which reduces the patient’s risk for atherosclerosis. Educating patients aged 65 and older about the role of statin therapy in preventing cardiovascular events, stroke, and vascular …
Simulation As A Multidisciplinary Team Approach In Health Care Programs In An Urban University Setting, Geraldine Fike, Dawn Blue, Guillermo Escalante, Phoebe (Yeon) S. Kim, Jose A. Munoz
Simulation As A Multidisciplinary Team Approach In Health Care Programs In An Urban University Setting, Geraldine Fike, Dawn Blue, Guillermo Escalante, Phoebe (Yeon) S. Kim, Jose A. Munoz
Health Science and Human Ecology Faculty Publications
The poster provided here showcases results from a simulation study that began in the Spring Quarter of 2017 at CSU San Bernardino. The results presented here are based on four simulations conducted on campus in our nursing lab space. We incorporated the participation of 44 students in our study.
Patients are cared for by a nurse and multidisciplinary teams which may include physical therapists, social workers, and public health workers; however, students in health care programs usually will not experience necessary scenarios developing needed skills. Although needed skills are learned within the walls of the university they remain in a …
Computational Investigation Of The Biomechanics Of Babywearing In Regards To Developmental Dysplasia Of The Hip, Gaurav Girish
Computational Investigation Of The Biomechanics Of Babywearing In Regards To Developmental Dysplasia Of The Hip, Gaurav Girish
Doctoral Dissertations and Master's Theses
Developmental Dysplasia of the Hip (DDH) is a congenital condition where an infant’s hip socket is either loose or otherwise unstable. DDH causes a joint instability where the femoral head is not properly situated inside the acetabulum. Etiology of the condition is in part congenital and developmental, with a difference of DDH prevalence between ethnicities. Incidence of DDH is also in some part dependent on cultural practices and activities of the mother and child. The exact nature of this cultural incidence is not clearly understood. A computational approach is hypothesized to identify the impact of babywearing position on the healthy …
Improving Service Delivery Through Provider Training: A Process Evaluation Of The Veterans Affairs Palo Alto Health Care System “Commitment To Serve” Workshop, Ismael Barrera
Master's Projects
As the customer-focused management strategies gradually advances into all of the VISNs [Veterans Integrated Service Networks], the Veterans Health Administration in Palo Alto, California implemented a customer service training program for employees to meet the diverse and complex needs of its customers. This research will analyze whether participants in this training, known as Commitment to SERVE, believe that it is achieving its goal. In other words, does the Veterans Affairs Palo Alto Health Care System (VAPAHCS) staff perceive the Commitment to SERVE workshop as a beneficial customer service training program?
The Pathway To The Use Of A Structured And Supported Approach To Debriefing, Anne H. Zachry, S. B. Lancaster
The Pathway To The Use Of A Structured And Supported Approach To Debriefing, Anne H. Zachry, S. B. Lancaster
Faculty Presentations
Debriefing plays a critical role in the transfer of knowledge in simulation education. Various methods are used in the debriefing process based on a variety of factors; this presentation sheds light on the pathway to the use of a structured and supported approach as traversed in the Department of Occupational Therapy at the University of Tennessee Healthcare Center as well as reflections and lessons learned along the way. Engagement in this session will allow learners to further develop their debriefing skills through exposure to information about strategies to use in the debriefing process that can be used as part of …
Measuring The Impact Of Patient-Engaged Research: How A Methods Workshop Identified Critical Outcomes Of Research Engagement, Ellis C. Dillon, Leah Tuzzio, Sarah Madrid, Heather Olden, Robert T. Greenlee
Measuring The Impact Of Patient-Engaged Research: How A Methods Workshop Identified Critical Outcomes Of Research Engagement, Ellis C. Dillon, Leah Tuzzio, Sarah Madrid, Heather Olden, Robert T. Greenlee
Journal of Patient-Centered Research and Reviews
Purpose: While strategies to evaluate the influence of engaging patient partners in research, such as the Patient-Centered Outcomes Research Institute (PCORI) WE-ENACT surveys, are beginning to emerge, a systematic set of measures for assessing the impact of patient engagement in research (PER) on study approaches and outcomes is lacking. This article describes a workshop and process used to identify and develop Critical Outcomes of Research Engagement (COREs). It proposes preliminary measures for assessing the impact of PER on the research process and outcomes of research studies.
Methods: A group of 24 researchers and 5 patient partners participated in a PCORI-funded …
Positive Impact On Patient Satisfaction And Caregiver Identification Using Team Facecards: A Quality Improvement Study, Nicole M. Martin, Khalil Odeh, Lamya Boujelbane, Marvi V. Rijhwani, Susan Olet, Aijaz Noor, Colleen Nichols, Richard Battiola
Positive Impact On Patient Satisfaction And Caregiver Identification Using Team Facecards: A Quality Improvement Study, Nicole M. Martin, Khalil Odeh, Lamya Boujelbane, Marvi V. Rijhwani, Susan Olet, Aijaz Noor, Colleen Nichols, Richard Battiola
Journal of Patient-Centered Research and Reviews
Background: Patients satisfaction is an increasingly important metric in measuring the quality of care that hospitals and physicians provide. It can be difficult for patients to remember their providers and their roles, all of which may potentially impact a patient’s overall satisfaction.
Purpose: To see if giving facecards with pictures and names of caregivers and description of roles improved patient satisfaction and identification of care team members.
Methods: Team facecards were designed and distributed to the patients during the interventional period of the study. Patients’ identification of team members, the role of each physician and overall satisfaction was measured using …
College Students, Experiences On Smart Phone Technology Usage: A Qualitative Content Analysis Study, Fatemeh Jafarzadeh-Kenarsari, Parand Pourghane
College Students, Experiences On Smart Phone Technology Usage: A Qualitative Content Analysis Study, Fatemeh Jafarzadeh-Kenarsari, Parand Pourghane
The Qualitative Report
Besides many benefits of the cell phone technology, numerous arguments are raised on the different and important negative effects of such a technology. This qualitative content analysis study explored the common usages of smart phone technology, its challenges, and benefits among Iranian college students. Participants were 32 bachelor degree students who were recruited using purposive sampling method with maximum variation. Data were collected through 11 individual semi-structured interviews and 3 focus group discussions (5-8 students in each group). Data analysis was done based on a conventional content analysis approach. Data analysis resulted in 3 main themes and 12 sub-themes. The …
Evaluating Patient Preferences For Different Incentive Programs To Optimize Pharmacist-Provided Patient Care Program Enrollment, Daniel M. Tomaszewski, Tim Cernohaus, Rajiv Vaidyanathan
Evaluating Patient Preferences For Different Incentive Programs To Optimize Pharmacist-Provided Patient Care Program Enrollment, Daniel M. Tomaszewski, Tim Cernohaus, Rajiv Vaidyanathan
Pharmacy Faculty Articles and Research
BACKGROUND: Employers have increased efforts to engage employees in health and wellness programs. Providing employees with incentives to participate in these programs has been shown to improve overall enrollment and engagement. One program that has had challenges with enrollment and engagement is medication therapy management (MTM).
OBJECTIVES: To (a) determine how individuals evaluate different financial incentives to improve participation in an MTM program and (b) measure the effect of participant characteristics on incentive preference.
METHODS: This study was composed of a paper-based survey administered to participants after focus group sessions. Participants included MTMeligible beneficiaries from 2 employer groups and included …
Reducing Medication Errors In Pneumonia Patients During Transitions Of Care, Laressa Bethishou, Noah Fang, Lisa Shieh
Reducing Medication Errors In Pneumonia Patients During Transitions Of Care, Laressa Bethishou, Noah Fang, Lisa Shieh
Pharmacy Faculty Articles and Research
Purpose: At Stanford Health Care, as part of a hospital-wide initiative to reduce pneumonia readmission rates, an interdisciplinary collaborative effort was created between physicians and transitions of care (ToC) pharmacists to optimize discharge planning and medication management for pneumonia patients. The purpose of this study was to describe the impact of the ToC pharmacist in identifying and reducing medication errors on discharge for pneumonia patients.
Methodology: Retrospective chart review was conducted on patients discharged with a pneumonia diagnosis between December 2015 to Feb 2016. Patients were stratified based on whether they received ToC pharmacist medication review vs. standard …
Strategi Pemasaran Poli Bedah Estetik Bali Royal Hospital (Bros) Denpasar, Deity Indrayati Nugraha
Strategi Pemasaran Poli Bedah Estetik Bali Royal Hospital (Bros) Denpasar, Deity Indrayati Nugraha
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
This study aims to create a good marketing strategy to determine the problems faced so it is expected that in the end the number of visits to the aesthetic surgery surgery BROS Denpasar has increased. This research uses qualitative method with observation, and in-depth interview. From the product-price mix, there are several strategies, namely by providing variations of products or additional services, buying aesthetic surgical instruments with the latest technology, and can also lower the rates of aesthetic surgery services. For the price place mix, the strategy is to move the esthetic surgical poly to a more private room. The …
Analisis Kesiapan Rumah Sakit Umum Daerah Kramat Jati Menjadi Health Promoting Hospital Tahun 2017, Winarto Winarto
Analisis Kesiapan Rumah Sakit Umum Daerah Kramat Jati Menjadi Health Promoting Hospital Tahun 2017, Winarto Winarto
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
The readiness of Regional General Hospital (RSUD) of Kramat Jati to become Health Promoting Hospital (HPH) is very important based on Health Promotion Standard of Ministry of Health Republic of Indonesia Year 2011. Therefore, the purpose of this research is to know the preparedness of RSUD Kramat Jati become Health Promoting Hospital, done by qualitative approach. The results showed that from six (6) standard of hospital health promotion, one (1) standard of hospital health promotion has been fulfilled by RSUD Kramat Jati, while five (5) standard of health promotion of hospital have not been fulfilled. Preparation of technical policies for …
Analisis Kesiapan Sistem Remunerasi Berdasarkan Peraturan Gubernur Provinsi Dki Jakarta Nomor 222 Tahun 2016 Di Rsud Pesanggrahan Tahun 2017, Endah Kartika Dewi
Analisis Kesiapan Sistem Remunerasi Berdasarkan Peraturan Gubernur Provinsi Dki Jakarta Nomor 222 Tahun 2016 Di Rsud Pesanggrahan Tahun 2017, Endah Kartika Dewi
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
RSUD Pesanggrahan as a Health Service Unit of Special Capital Region of Jakarta which has applied financial pattern of Regional Public Service Board (BLUD). This research uses quantitative with simulation of system calculation to be applied and qualitative with explore stakeholder perception readiness with indepth interview. From the result of research it is known that in general the informant is satisfied with the income received now. And from the simulate conducted, RSUD Pesanggrahan has not been able to apply the system based on Governor Regulation No. 222/2016 yet. Suggestion to the Health Department as a regulator is to give the …
Analisis Elemen Bauran Pemasaran Yang Mempengaruhi Loyalitas Pelanggan Rumah Sakit: Systematic Review, Elisabeth Dewi Agustine
Analisis Elemen Bauran Pemasaran Yang Mempengaruhi Loyalitas Pelanggan Rumah Sakit: Systematic Review, Elisabeth Dewi Agustine
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Increasing the number of hospitals improves the competitive of medical services. Hospitals must have the right marketing strategy to retain old customers and attract new customers. To increase of the hospital customer loyalty, the marketing mix can be use as tool. Aim: To know the marketing mix elements that influence the loyalty of hospital customers. Preferred report items for systematic reviews and meta-analyzes (PRISMA) are evidence based methods for performing systematic reviews. There are 33.33% of the 9 studies that mention 7 elements (product, price, place, people, process, physical evidence, promotion) in the marketing mix, all of which affect the …
Analisis Penerapan Program Pencegahan Dan Pengendalian Infeksi Di Ruang Rawat Inap Rsud Tebet Tahun 2017, Tetyana Madjid
Analisis Penerapan Program Pencegahan Dan Pengendalian Infeksi Di Ruang Rawat Inap Rsud Tebet Tahun 2017, Tetyana Madjid
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
The focus of this research is indentifying infection prevention and control program in Tebet hospital through observation of nursing action on infusion, bandage, injecting and waste management, and indentifying nurse’s characteristics, policies, facilities, monitoring and reporting of infection. This research using qualitative and quantitative approach. Unit analysis of this research is 105 of actions mentioned above by all nurses in the inpatient room. The results of this study show that most of the actions performed by the nurses were good, analysis with univariat, bivariat and logistic regression of multivariat. The most affecting variables is the reporting of infection. Suggestions for …
Analisis Standar Kompetensi Tenaga Kesehatan Di Rumah Sakit Bhakti Yudha Depok Tahun 2017, Syifa Silviana
Analisis Standar Kompetensi Tenaga Kesehatan Di Rumah Sakit Bhakti Yudha Depok Tahun 2017, Syifa Silviana
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
Competency of healthcare provider has significant impact on performance of the hospital. Measuring competency of healthcare provider are essential to improve better quality of service provisioned. The study evaluates competency of healthcare provider at Bhakti Yudha Hospital by using the competency standards established by multiple organizations of Indonesian national healthcare provider association mapped against eight units of health provider. The result stated that competency level of healthcare providers at Bhakti Yudha Hospital have had not met the expectations. It is concluded that working experiences and number of relevant training received has significant impact on competency level of healthcare provider.
Penerapan Lean Thinking Untuk Mereduksi Waktu Boarding Pasien Igd Ke Rawat Inap Di Rsud Koja Tahun 2017, Theryoto Theryoto
Penerapan Lean Thinking Untuk Mereduksi Waktu Boarding Pasien Igd Ke Rawat Inap Di Rsud Koja Tahun 2017, Theryoto Theryoto
Jurnal ARSI : Administrasi Rumah Sakit Indonesia
The implementation of the National Health Insurance Program (Program JKN) affects the increased number of patients to emergency unit and boarding patients that resulting crowding in the emergency unit. Koja Hospital has implemented bed management in order to reduce the boarding time of emergency unit patients but has not succeeded, so an effort to help reducing the boarding time of emergency unit patients to inpatient in order to continuous improvement was done using the lean thinking principle. This research uses operational research method and intervention with PDCA (Plan, Do, Check, Action) cycle. The study revealed that lean thinking approach could …
Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer
Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer
Purdue Journal of Service-Learning and International Engagement
The Tumaini Children’s Drop-In Center is a daytime drop-in center for the street children of Eldoret, Kenya. It is part of a partnership between the Purdue University College of Pharmacy, the Academic Model Providing Access to Healthcare program, Eldoret community members, and numerous individuals in both Kenya and the US. Through the efforts of local staff and Purdue student pharmacists, who work at the local hospital on an eight-week clinical rotation, the center has helped a population of nearly 400 local street children by providing a safe haven from life on the streets. Purdue student pharmacists aid the center by …
Managing The Cost Of Diabetes, Laressa Bethishou
Managing The Cost Of Diabetes, Laressa Bethishou
Pharmacy Faculty Articles and Research
"This is of concern to health care providers because inadequate management of diabetes results in short- and long-term complications. Patients with diabetes and no health insurance have fewer physician visits and are prescribed fewer medications for management of their diabetes. Patients with diabetes make up 11.9% of all emergency department visits in the United States.Hispanic and non-Hispanic blacks are at greater risk for developing diabetes and serious associated health complications, including chronic kidney disease. This may be attributed to a combination of genetics, diet, and exercise. However, access to health care resources may also play an important role."
Drawbacks Of Utilizing The Logit Link In Propensity Score Weighting Adjustment, Evrim Oral
Drawbacks Of Utilizing The Logit Link In Propensity Score Weighting Adjustment, Evrim Oral
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
International Black-Market Organ Trade, Marni E. Granzow
International Black-Market Organ Trade, Marni E. Granzow
Student Publications
The human organ trade is a global epidemic as citizens of developed-countries look to developing-countries to find organ donors, specifically exploiting the poor for their own personal gain. The impoverished organ donors are treated in an inhumane manner, as they are often left with serious medical complications and are not treated equally in the transaction.
Mathematical Modeling For Predicting Chemotherapy And Nanoparticle Treatment Efficacy In Breast Cancer, Terisse Arielle Brocato
Mathematical Modeling For Predicting Chemotherapy And Nanoparticle Treatment Efficacy In Breast Cancer, Terisse Arielle Brocato
Biomedical Engineering ETDs
Breast cancer treatment response varies by subtype, treatment regiment, and additionally by vasculature characteristics. For this reason, breast cancer is a model disease for the development of both targeted therapy and prognostic and predictive biomarkers. Mathematical modeling allows for personalized patient specific prediction of treatment outcome based on parameters found to be important to the cancer type. Mathematical modeling is beneficial in providing insight into why cancer treatment fails and in what cases, additionally determining what characteristics result in a successful treatment. Presented in Chapter 1 is a scientific introduction and discussion focusing on representative modeling works specified towards breast …