Other Medicine and Health Sciences Commons^™

Effect Of Injury Mechanism And Severity On The Molecular Pathophysiology Of Traumatic Brain Injury, Brandon Mcdonald

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Traumatic brain injury (TBI) mechanism and severity are heterogenous clinically, resulting in a multitude of physical, cognitive, and behavioral deficits. However, approximately 80% suffer from milder injuries. Thus, examining pathophysiological changes associated with mild TBI is imperative for improving clinical translation and evaluating the efficacy of potential therapeutic strategies. Through this work, we developed models of TBI, ranging in both injury mechanism and severity, using an electromagnetic controlled cortical impact (CCI) device. First, we characterized and optimized a closed head, mild TBI model (DTBI) to determine the clinical translatability and practicality of producing repeated mild injuries. Interestingly, we determined that …

Health Information Management Practice In Health Care Delivery System: A Case Study Of University Of Medical Sciences Teaching Hospital Complex, Ondo, Ondo State, Nigeria, Tajudeen Temitayo Adebayo Dr, Sunday Ayo Gbabe Mr

Library Philosophy and Practice (e-journal)

The aim of this research work is to ascertain the relevance of health information management practice in health care delivery system. This research reviewed past and presents literature that of relevance to this research topic. Descriptive survey research design was adopted. Questionnaire was used to collect necessary information through probability sampling method and specifically the simple random sampling. Fifty (50) questionnaires were distributed to Health Information Practitioners at University of Medical Sciences Teaching Hospital Complex, Ondo and all the fifty questionnaires were retrieved for data analysis. It has been proved that HIM practice plays a very vital role in effective …

Clinical Coding And Indexing As Indispensable Tool In Health Care, Teaching And Research: A Case Study Of Obafemi Awolowo Teaching Hospital Complex (Oauthc) Ile-Ife, Osun State, Tajudeen Temitayo Adebayo Dr, Sadiq Anifat Afolabi Mrs, Soladayo Olabisi Fajuyigbe Mrs, Olayiwola Kayode Adepoju Dr, Michael Segun Omole Dr

Library Philosophy and Practice (e-journal)

Clinical coding and indexing is the process by which medical procedure and diagnoses are represented and displayed by universal code number. It is a system that plays a key role in modern healthcare and also allow statistical analyses of diseases and treatment, diagnoses related group, reimbursement, easier observance and tracking of epidemic and production events. The study therefore aimed at examining coding and indexing as indispensable tool in healthcare, teaching and research; a case study of OAUTHC Ile-Ife, Osun State.

The target population was 152 health records officer in OAUTHC, Ile-Ife. A cross-sectional research method was adopted. Data was collected …

Bibliometric Analysis Of Bioscience Trends Journal (2007-2017): Knowledge Dynamics And Visualization, Anis Fuad, Yuan-Chii Gladys Lee, Chien-Yeh Hsu

Library Philosophy and Practice (e-journal)

BioScience Trends (BST) is a peer-reviewed journal belongs to the International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA) Group of Japan. Despite a decade of existence, no study was performed to measure the bibliometric profile of the journal. The objective of this study was to investigate the bibliometric characteristic of BST. A bibliometric analysis will specifically measure: 1) growth rate of the scientific publications, 2) dynamics of authorship and collaboration pattern; 3) core research themes of articles that have been published, and 4) citation pattern of BST. Bibliographical archives of BST were obtained from the Core Collection …

Health Information Needs For The Aged In The Society, Tajudeen Temitayo Adebayo Phd, Michael Segun Omole Phd

Library Philosophy and Practice (e-journal)

The Aged are prone to a lot of challenges as they assume the latent phase of their life. These challenges include loneliness, incapacitates, and degenerative diseases among others. To adequately coop with this problems, information becomes an essential ingredients. This work reports on the importance of identify the types of information needed by the aged, sources and channels of information available to them and how the information may help in modifying their life. The general inputs expected from Librarian were also discussed.

Influence Of National Health Management Information System, On The Planning Of Health Care Services In Nigeria, Michael Segun Omole Dr., Tajudeen Temitayo Adebayo Dr., Rasaq Adetona Adio, Faruk Abubakar Umar, Michael Babatunde Adeojo, Aliyu Wada

Library Philosophy and Practice (e-journal)

This paper reported on the Influence of National Health Management Information System on the planning of health care services in Nigeria. The article, aimed at combining insights of how National Health Management Information System implementation, bridges different aspects of Health Care Service planning in Nigeria; through objective identification of the basic philosophy of NHMIS, its place in the National Health Policy, the concept of NHMIS and assessment of the effect of NHMIS on the planning of Health Care Services

The method used for this study is literature review and theoretical analysis. Inferences drawn from existing literatures and postulated theories indicated …

Health Information Management- A Tool For Effective Health Care Delivery In Nigeria; Mother And Child Hospital, Akure, Ondo State Experience, Tajudeen Temitayo Adebayo Dr., Ebenezer Seun Orimoloye Mr

Library Philosophy and Practice (e-journal)

The study investigates Health Information: A Tool for effective Health Care Delivery in Nigeria (Mother and Child Hospital, Akure Experience.). The descriptive survey design approach was employed and questionnaire was the research instruments. The patients, medical and paramedical staff (Doctors, HROs, Nurses, MLS and others) of the Mother and Child Hospital, Akure were used as the respondents; convenience sampling technique was adopted to get the samples involved. Two hundred questionnaires were administered and all were retrieved by the researcher and was used for this study. Data presentation and analysis were done using frequencies, simple percentages and chi-square statistics. The result …

An Exploration Of The Effect Of Nosology On Clinical Coding In Nigeria, Tajudeen Temitayo Adebayo, Michael Segun Omole Dr.

Library Philosophy and Practice (e-journal)

The article aimed at exploring how Nosology bridges different aspects of Clinical Coding in Nigeria; through objective identification of the basic concept of Nosology, its place in the Clinical Coding and assessment of the effect of Nosology on Clinical Coding. The presentation started with introduction, followed by discussion on Importance of Clinical Coding and the Challenges of Clinical Coding. The Concept of Nosology, the Roles of Nosology in Clinical Coding was extensively discussed. Also, relationship between Nosology and Clinical Coding was established and this was followed by summary, conclusion and recommendations. The method used for this study is literature review …

Information Accessibility And Risk Practices Of People Living With Hiv/Aids In South-West, Nigeria., Tajudeen Temitayo Adebayo, Michael Segun Omole Dr., Muyiwa Adekunle Amin, Adebayo Olawepo Ogunniran

Library Philosophy and Practice (e-journal)

People living with HIV/AIDS (PLWHA) access information from different sources. They are being warned regularly on the need to stay away from all forms of risk practices which may cause further spread of the dreaded diseases. The study endeavour to investigate the level of information access opened to PLWHA and tried to find the relationship between information accessibility and risk practices.

The study adopted survey research design of correlational type. The target population was 8,135PLWHA in the selected three health institutions. Pooled standard error of proportion was used to determine 339 PLWHA and critical incident technique was used to …

Culture And The Development Of Traditional Medicine In Africa, Rowland Edet, Oyedolapo Isaac Bello, Julianah Babajide

Department of Sociology: Faculty Publications

Traditional medicine has been the dominant healthcare system in Africa before westernization, civilization and colonialism. For people living in the rural areas, traditional medicine is easily available, accessible and affordable. The purpose of this paper is to examine how the cultural way of the life of Africans has contributed to the emergence and development of traditional therapeutic systems in the continent. By explaining the way Africans perceive illness and disease, this paper argues that various forms of healing were predicated on the sociocultural environment of the people. The paper therefore opts for concerted efforts in the development of traditional medicine …

Experimental Evaluation Of The Importance Of Colonization History In Early-Life Gut Microbiota Assembly, Inés Martínez, Maria X. Maldonado-Gomez, João Carlos Gomes-Neto, Hatem Kittana, Hua Ding, Robert J. Schmaltz, Payal Joglekar, Roberto Jiménez Cardona, Nathan L Marsteller, Steven W. Kembel, Andrew K. Benson, Daniel A. Peterson, Amanda Ramer-Tait, Jens C. Walter

Department of Food Science and Technology: Faculty Publications

The factors that govern assembly of the gut microbiota are insufficiently understood. Here, we test the hypothesis that inter-individual microbiota variation can arise solely from differences in the order and timing by which the gut is colonized early in life. Experiments in which mice were inoculated in sequence either with two complex seed communities or a cocktail of four bacterial strains and a seed community revealed that colonization order influenced both the outcome of community assembly and the ecological success of individual colonizers. Historical contingency and priority effects also occurred in Rag1^-/- mice, suggesting that the adaptive immune system …

A Gut Pathobiont Synergizes With The Microbiota To Instigate Inflammatory Disease Marked By Immunoreactivity Against Other Symbionts But Not Itself, João Carlos Gomes-Neto, Hatem Kittana, Sara Mantz, Rafael R. Segura Munoz, Robert J. Schmaltz, Laure B. Bindels, Jennifer L. Clarke, Jesse M. Hostetter, Andrew K. Benson, Jens Walter, Amanda Ramer-Tait

Department of Food Science and Technology: Faculty Publications

Inflammatory bowel diseases (IBD) are likely driven by aberrant immune responses directed against the resident microbiota. Although IBD is commonly associated with a dysbiotic microbiota enriched in putative pathobionts, the etiological agents of IBD remain unknown. Using a pathobiont-induced intestinal inflammation model and a defined bacterial community, we provide new insights into the immune-microbiota interactions during disease. In this model system, the pathobiont Helicobacter bilis instigates disease following sub-pathological dextran sulfate sodium treatment. We show that H. bilis causes mild inflammation in mono-associated mice, but severe disease in the presence of a microbiota, demonstrating synergy between the pathobiont and microbiota …

Enduring Chronic Kidney Disease: An Investigation Of Psychosocial Factors And Life Satisfaction In Older Adults Receiving Dialysis Treatment, Bailee Sobotka

Honors Theses

Chronic kidney disease is a condition during which the kidneys begin to shut down and no longer filter blood efficiently. Once the disease has progressed far enough, dialysis treatments are mandatory to sustain life. To further understand how older adults receiving dialysis treatments cope with their disease, psychosocial factors were evaluated to investigate possible correlations with life satisfaction using a Life Satisfaction Index Z (LSI-Z). Expected correlations with life satisfaction were sociability, financial satisfaction, importance of spirituality, and activities of daily living scores. Interviews were conducted with 30 dialysis patients and results were analyzed using various statistical measures. Significant correlations …

Lactose Intolerance: An Overview Of The Facts And Their Implications, Noelle M. Yeo

Honors Theses

Lactose intolerance is often blamed for the symptoms such as bloating, diarrhea, gas, abdominal pain, and nausea, that ail many people. Patients often do not seek proper diagnosis from a physician and create their own treatment plans, severely restricting lactose intake, without professional guidance. Even those who do seek the care of a physician find that diagnosis is complicated by less-than ideal testing and confusion due to the symptoms common to many other conditions. The misconceptions and inability to confirm a diagnosis of lactose intolerance can cause nutrient deficiencies in these patients, as well as begin a pattern of unnecessary …

The Host Microbiome Regulates And Maintains Human Health: A Primer And Perspective For Non-Microbiologists, Sunil Thomas, Jacques Izard, Emily Walsh, Kristen Batich, Pakawat Chongsathidkiet, Gerard Clarke, David A. Sela, Alexander J. Muller, James M. Mullin, Korin Albert, John P. Gilligan, Katherine Diguilio, Rima Dilbarova, Walker Alexander, George P. Prendergast

Department of Food Science and Technology: Faculty Publications

Humans consider themselves discrete autonomous organisms, but recent research is rapidly strengthening the appreciation that associated microorganisms make essential contributions to human health and well being. Each person is inhabited and also surrounded by his/her own signature microbial cloud. A low diversity of microorganisms is associated with a plethora of diseases, including allergy, diabetes, obesity, arthritis, inflammatory bowel diseases, and even neuropsychiatric disorders. Thus, an interaction of microorganisms with the host immune system is required for a healthy body. Exposure to microorganisms from the moment we are born and appropriate microbiome assembly during childhood are essential for establishing an active …

Engaging Parents To Promote Children’S Nutrition And Health: Providers’ Barriers And Strategies In Head Start And Child Care Centers, Dipti A. Dev, Courtney Byrd-Williams, Samantha Ramsay, Brent A. Mcbride, Deepa Srivastava, Ashleigh L. Murriel, Chrisa Arcan, Anna M. Adachi-Mejia

Department of Child, Youth, and Family Studies: Faculty Publications

Purpose: Using the Academy of Nutrition and Dietetics benchmarks as a framework, this study examined childcare providers’ (Head Start [HS], Child and Adult Care Food Program [CACFP] funded, and non-CACFP) perspectives regarding communicating with parents about nutrition to promote children’s health.

Design: Qualitative.

Setting: State-licensed center-based childcare programs.

Participants: Full-time childcare providers (n ¼ 18) caring for children 2 to 5 years old from varying childcare contexts (HS, CACFP funded, and non-CACFP), race, education, and years of experience.

Methods: In-person interviews using semi-structured interview protocol until saturation were achieved. Thematic analysis was conducted.

Results: Two overarching themes were barriers and …

The 1939 Dickinson-Belskie Birth Series Sculptures: The Rise Of Modern Visions Of Pregnancy, The Roots Of Modern Pro-Life Imagery, And Dr. Dickinson’S Religious Case For Abortion, Rose Holz

Women's and Gender Studies Program: Faculty Publications

This multidisciplinary essay examines the hugely influential—yet surprisingly overlooked—Birth Series sculptures. Created in 1939 by Dr. Robert L. Dickinson (obstetrician-gynecologist and leader of the Planned Parenthood Federation of America) and sculptor Abram Belskie, they illustrate the process of human development from fertilization through delivery. First displayed at the 1939–1940 World’s Fair in New York City, they were reproduced in a variety of forms and sent out across the United States and overseas. Hardly a brief fad, their popularity persisted into the 1980s. This essay has four purposes. First, it tells the stories of Dickinson and Belskie to appreciate their contributions …

Encoding Of Saltatory Tactile Velocity In The Adult Orofacial Somatosensory System, Rebecca Custead

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Processing dynamic tactile inputs is a key function of somatosensory systems. Spatial velocity encoding mechanisms by the nervous system are important for skilled movement production and may play a role in recovery of motor function following neurological insult. Little is known about tactile velocity encoding in trigeminal networks associated with mechanosensory inputs to the face, or the consequences of movement.

High resolution functional magnetic resonance imaging (fMRI) was used to investigate the neural substrates of velocity encoding in the human orofacial somatosensory system during unilateral saltatory pneumotactile inputs to perioral hairy skin in 20 healthy adults. A custom multichannel, scalable …

The Relationship Between Physical Activity And Diet And Young Children's Cognitive Development: A Systematic Review, Pooja S. Tandon, Alison Tovar, Avanthi T. Jayasuriya, Emily Welker, Daniel J. Schober, Kristen Copeland, Dipti A. Dev, Ashleigh L. Murriel, Dima Amso, Dianne S. Ward

Department of Child, Youth, and Family Studies: Faculty Publications

Objective. Given the high prevalence of suboptimal nutrition and low activity levels in children, we systematically reviewed the literature on the relationship between physical activity and dietary patterns and cognitive development in early childhood (six months to five years).

Methods. In February 2016, we conducted two different searches of MEDLINE, PsycINFO, and ERIC. Each search included either physical activity (including gross motor skills) or diet terms, and neurocognitive development outcome terms. Included studies were in English, published since 2005, and of any study design in which the physical activity or diet measure occurred prior to age five.

Results. For physical …

Effects Of Local Blood Flow On Muscle Stiffness, Megan E. White, Aaron J. Engel, Greg Bashford

UCARE Research Products

Muscle injuries, in the form of strains or even tears, affect millions of people each year through undue tension on muscles during everyday activities, work tasks, or physical activity including sports or working out. These injuries can take from a few weeks to even months to heal, with patients having to deal with inflammation, swelling, and pain throughout the healing process. Scar tissue also forms when the muscle is injured, which regenerates throughout the healing process, but never fully recovers to its state prior to injury. This scar tissue is thought to make the muscle more prone to subsequent injury, …

The Differentiation And Protective Function Of Cytolytic Cd4 T Cells In Influenza Infection, Deborah M. Brown, Anna T. Lampe, Aspen M. Workman

School of Biological Sciences: Faculty Publications

CD4 T cells that recognize peptide antigen in the context of class II MHC can differentiate into various subsets that are characterized by their helper functions. However, increasing evidence indicates that CD4 cells with direct cytolytic activity (CD4 CTL) play a role in chronic as well as acute infections, such as influenza A virus (IAV) infection. In the last couple of decades, techniques to measure the frequency and activity of these cytolytic cells has demonstrated their abundance in infections, such as human immunodeficiency virus, mouse pox, murine gamma herpes virus, cytomegalovirus, Epstein–Barr virus, and influenza among others. We now appreciate …

Mechanisms By Which Dietary Ellagic Acid Attenuates Obesity And Obesity-Mediated Metabolic Complications, Inhae Kang

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Ellagic acid (EA) is a polyphenol found in various fruits and plants, such as berries, pomegranates, muscadine grapes, nuts and bark of oak tree. EA has been known to exhibit anti-inflammatory and anti-proliferative effects in various types of cancer. However, little is known about the effects of EA on obesity. Herein, 1) the lipid-lowering role of EA was identified in primary human adipose stem cells (hASCs) and human hepatoma Huh7 cells; 2) the molecular mechanisms by which EA attenuates adipogenesis by epigenetic modification were identified; 3) the effects of EA on high fat and high sucrose-mediated obesity was …

A Thematic Study Of Islamic Perspectives In Scopus Indexed Articles. Implications On Medical Imaging., Zainul Ibrahim Zainuddin

Library Philosophy and Practice (e-journal)

Discussions pertaining to the various Islamic dimensions are actively being undertaken in the media. Within the academic circle, journal articles are accepted as an effective media in the dissemination of knowledge. Articles with Islamic perspectives can be found in disciplines that include Medicine, Banking, Economics and Finance. However, there is little to suggest of the types and frequencies of Islamic perspectives in Medical Imaging. This paper attempts to fill the gap. The methodology involves the use of Scopus database and its interactive search facility. The justification of using Scopus is the user-friendliness of its search interface and the ability to …

Social Contexts Of Infant Feeding And Infant Feeding Decisions, Ellen J. Schafer, Natalie A. Williams, Siri Digney, Marion E. Hare, Sato Ashida

Department of Child, Youth, and Family Studies: Faculty Publications

Background: Infant feeding takes place within a network of social relationships. However, the social context in which infant feeding advice is received remains underresearched.

Objective: The objective of this study was to evaluate the social contexts of infant feeding by examining individual and relationship characteristics of mothers and network members associated with advice to exclusively breastfeed, exclusively formula feed, or use a combination of breast milk and formula.

Methods: Information about 287 network members was reported by 80 low-income mothers during a one-time survey. Characteristics of relationships associated with mothers receiving advice (exclusively breastfeed/formula feed, combination feed) from each network …

Blast-Induced Mild Traumatic Brain Injury Through Ear Canal: A Finite Element Study, Praveen Akula, Yi Hua, Linxia Gu

Department of Mechanical and Materials Engineering: Faculty Publications

Purpose The role of ear canal in transmitting blast waves to the brain is not clear. The goal of this work is to characterize the influence of ear canal on blast-induced mild traumatic brain injury through a computational approach.

Methods A three-dimensional human head model with single-side ear canal details was reconstructed from computed tomography images. The ear canal was positioned either facing the incident blast wave or facing away from the blast wave.

Results The blast wave-head interaction has demonstrated that the overpressure within the ear canal was substantially amplified when the ear directly faced the blast wave. When …

Analysis Of Drug Interactions With Lipoproteins By High Performance Affinity Chromatography, Matthew R. Sobansky

Department of Chemistry: Dissertations, Theses, and Student Research

High density lipoprotein (HDL), low density lipoprotein (LDL), and very low density lipoprotein (VLDL) are lipoproteins previously shown to bind many basic and neutral hydrophobic drugs in serum. These interactions impact the distribution, delivery, metabolism, and excretion of drugs and are important in determining drug activity, pharmacokinetics, and toxicity in the human body. Information about drug-lipoprotein interactions and the strength of these interactions can be useful in determining the distribution of drugs following administration.

The research presented in this dissertation uses high performance affinity chromatography (HPAC) and packed columns to study binding of the drug propranolol to immobilized lipoproteins such …

The Environmental And Health Costs Of Alternative Diets: A Comparative Study Of The U.S. Diet Relative To The French, Japanese, Mediterranean, And Nordic Diets, Sarah Rehkamp

Department of Agricultural Economics: Dissertations, Theses, and Student Research

This thesis contributes to the literature on sustainable consumption by using scenario analysis to evaluate the environmental and health costs of the U.S. diet relative to the French, Japanese, Mediterranean, and Nordic diets, identified in the literature as healthier diets. As a first step in estimating environmental costs, the energy efficiencies of each diet are calculated by decomposing each of the diets into their respective components. Then, the dietary efficiencies are translated into CO₂ emissions. As a first step in estimating health costs, a pooled cross-section time-series dataset is used to find the association between BMI and five countries, …

Perceived Impacts Of A Public Health Training Center Field Placement Program Among Trainees: Findings From A Small Group Externship Experience, Patrik Johansson, Brandon Grimm, Tarik Abdel-Monem, Stacey J. Hoffman, Mark Dekraai, Analisa Mcmillan

University of Nebraska Public Policy Center: Publications

There is heightened interest in identifying the impact of the federally funded Public Health Training Center (PHTC) program. Although evaluation studies have been conducted of public health training in general, evaluations of PHTC programs are rare. Field placement components are congressionally mandated requirements of PHTCs. Field placements are typically intensive, supervised externships for students to gain public health experience with local health departments or non-profit organizations. We have found no published evaluations of PHTC field placement components. This may be because of their small size and unique nature. We designed and evaluated a 200-h field placement program at an established …

Grain Sorghum Whole Kernel Oil Lowers Plasma And Liver Cholesterol In Male Hamsters With Minimal Wax Involvement, Bo Hyun Lee, Thomas M. Carr, Curtis Weller, Susan L. Cuppett, Ismail M. Dweikat, Vicki Schlegel

Department of Food Science and Technology: Faculty Publications

The lipid fraction of the grain sorghum whole kernel (GS-WK) (i.e., phytosterol rich oil or policosanol rich wax) responsible for lowering cholesterol in hamsters fed the crude lipid (wax + oil) was determined. As expected, hamsters fed an atherogenic diet for a four week period presented with higher plasma non-HDL plasma and liver esterified cholesterol than those on the low fat diet. However, the atherogenic diet containing 5% (w/w) oil significantly lowered non-HDL plasma and liver cholesterol. Although the 5% wax supplement did not affect either plasma or liver cholesterol, excreted neutral sterol and bile acid were slightly higher than …

Using Quantitative Disease Dynamics As A Tool For Guiding Response To Avian Influenza In Poultry In The United States Of America, K. M. Pepin, E. Spackman, J. D. Brown, K. L. Pabilonia, Lindsey P. Garber, J. Todd Weaver, D. A. Kennedy, Kelly A. Patyk, K. P. Huyvaert, Ryan S. Miller, Alan B. Franklin, Kerri Pedersen, T. L. Bogich, P. Rohani, Susan A. Shriner, Colleen T. Webb, S. Riley

USDA Wildlife Services: Staff Publications

Wild birds are the primary source of genetic diversity for influenza A viruses that eventually emerge in poultry and humans. Much progress has been made in the descriptive ecology of avian influenza viruses (AIVs), but contributions are less evident from quantitative studies (e.g., those including disease dynamic models). Transmission between host species, individuals and flocks has not been measured with sufficient accuracy to allow robust quantitative evaluation of alternate control protocols. We focused on the United States of America (USA) as a case study for determining the state of our quantitative knowledge of potential AIV emergence processes from wild hosts …