Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (3)
- Bacteria (2)
- Bacteriology (2)
- Environmental Sciences (2)
- Immunology and Infectious Disease (2)
-
- Medical Sciences (2)
- Microbiology (2)
- Pathogenic Microbiology (2)
- Physical Sciences and Mathematics (2)
- Plants (2)
- Veterinary Medicine (2)
- Viruses (2)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Biology (1)
- Chemicals and Drugs (1)
- Comparative and Laboratory Animal Medicine (1)
- Diseases (1)
- Earth Sciences (1)
- Immunology of Infectious Disease (1)
- Laboratory and Basic Science Research (1)
- Medical Cell Biology (1)
- Medical Microbiology (1)
- Medical Molecular Biology (1)
- Medical Specialties (1)
- Natural Products Chemistry and Pharmacognosy (1)
- Natural Resources and Conservation (1)
- Oncology (1)
- Other Chemicals and Drugs (1)
- Keyword
-
- Rickettsia (2)
- Adenovirus (1)
- Bacterial pathogenesis (1)
- Biogeography (1)
- Breast cancer (1)
-
- Cancer therapy (1)
- Chemo-virotherapy (1)
- Chemotherapy (1)
- Combinationtherapy (1)
- Complement resistance (1)
- Flea-borne spotted fever (1)
- Host-pathogen interactions (1)
- Intracellular bacteria (1)
- Invasion biology (1)
- Invasive species (1)
- Oncolytic virology (1)
- Oncolytic virus (1)
- Prostate cancer (1)
- Rickettsia felis (1)
- Rickettsial transmission (1)
- Tranmission via ingestion (1)
- Virotherapy (1)
- Vitronectin (1)
Articles 1 - 6 of 6
Full-Text Articles in Organisms
Restoration Agriculture In Louisiana: On The Prospects And Ethics Of Creating A Permanent, Dynamic Agricultural System Suited For Louisiana's Environment, Noah Willsea
Honors Theses
No abstract provided.
Biogeography Of Biological Control: Spatial Variation In Agent-Host Interactions, Nathan Harms
Biogeography Of Biological Control: Spatial Variation In Agent-Host Interactions, Nathan Harms
LSU Doctoral Dissertations
Management of plant invasions using biological control has the potential to generate spatial patterns which reflect geographic or genetic variation in invader or control agents. Despite its rarity in practice, investigations into the biogeography of interacting species (i.e., plant invader and control agent) in the context of biological control can lend insights into species distribution-abundance patterns and provide predictions for spatial variation in control success. I explored spatial variability in biological control agent-plant interactions using two wetland weed study systems with large geographic distributions: flowering rush (Butomus umbellatus L.) and alligatorweed (Alternanthera philoxeroides (Mart.) Griseb). Through literature and …
Generation Of An Oncolytic Adenovirus Targeting The Cxcr4 And Cxcr7 Chemokine Receptors In Breast Cancer, Samia Melissa O'Bryan
Generation Of An Oncolytic Adenovirus Targeting The Cxcr4 And Cxcr7 Chemokine Receptors In Breast Cancer, Samia Melissa O'Bryan
LSU Doctoral Dissertations
Breast cancer is the most diagnosed cancer in women under 60 and the second most diagnosed cancer in women over 60. While treatments for localized breast cancer are quite successful with high survival rates at 99%, advanced breast cancer remains hard to treat with a nearly 75% decrease in survival. Current treatments are inefficient at treating advanced stages of breast cancer, and thus, new therapies are sorely needed to address the complexity of advanced stage breast cancer. The ideal therapy would be capable of systemic administration, targets cancer cells and spares normal tissue. Oncolytic adenovirus is an ideal therapeutic vector …
Infection Potential Of Rickettsia Felis Via Ingestion, Matthew M. Schexnayder
Infection Potential Of Rickettsia Felis Via Ingestion, Matthew M. Schexnayder
LSU Master's Theses
Rickettsia felis is the etiologic agent of flea-borne spotted fever (FBSF) in humans and a poorly described cause of fever in animals. It is transmitted by its primary arthropod vector and reservoir host, the cat flea Ctenocephalides felis. Known routes of Rickettsia felis transmission between Rickettsia felis-infected cat fleas and vertebrate hosts include cutaneous bites and contamination of cutaneous wounds with infective flea feces. The bulk of FBSF infections occur in young children in Africa, though infections of people at all ages all over the world have been confirmed. As mammals and young children frequently come into contact …
Paclitaxel Enhances Oncolytic Potential Of Herpes Simplex Virus Type-1 In Cancer Cells, Misagh Naderi
Paclitaxel Enhances Oncolytic Potential Of Herpes Simplex Virus Type-1 In Cancer Cells, Misagh Naderi
LSU Master's Theses
Taxanes are spindle poisons that bind to and stabilize microtubules resulting in mitotic arrest. Herpes simplex Typ-1 (HSV-1) virions utilize the microtubular network for intracellular transport during both virus entry and virus egress from infected cells. It has been reported previously that taxanes may synergize with oncolytic herpes simplex viruses in the treatment of experimental prostate and breast tumors in mice. Other reports have indicated that taxanes may inhibit viral replication in infected cells. In this study the previously characterized Oncolytic Herpes Simplex Virus type 1 (OSVP), which was constructed in Kousoulas lab was used in conjugation with paclitaxel (taxol) …
Characterization Of The Interaction Between R. Conorii And Human Host Vitronectin In Rickettsial Pathogenesis, Abigail Inez Fish
Characterization Of The Interaction Between R. Conorii And Human Host Vitronectin In Rickettsial Pathogenesis, Abigail Inez Fish
LSU Doctoral Dissertations
Spotted Fever Group Rickettsia are inoculated into the mammalian host during hematophagous arthropod feeding. Once in the bloodstream and during dissemination, the survival of these pathogens is dependent upon their ability to evade innate host defenses until a proper cellular target is reached. The establishment of a successful infection also relies on the ability of the bacteria to attach and invade target cells, as failure to do so results in destruction of the bacterium. Rickettsia conorii expresses an outer membrane protein, Adr1, which binds the multifunctional human glycoprotein, vitronectin, to promote resistance to complement mediated killing. Homologs of Adr1 are …