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Comparison Of Wild And Cultivated Extracts Of Cordyceps Sinensis Apoptotic Potential, Katelyn Staring
Comparison Of Wild And Cultivated Extracts Of Cordyceps Sinensis Apoptotic Potential, Katelyn Staring
Honors Theses
Cordyceps sinensis is a mushroom which contains the compound cordycepin (3’-deoxyadenosine), an analogue of adenosine. In Traditional Chinese Medicine (TCM), cordycepin has multipurpose pharmacological uses including purported anti-tumor effects. In the present study, cordycepin was extracted from the wild mushroom as well as from various commercially available cultivated extracts. Previous research in this lab has demonstrated that cultivated extracts contain less cordycepin than the wild mushroom. However, it is unclear if the decrease in cordycepin correlates with decreased activity. To measure anti-tumor activity, extracts were used to treat human breast cancer cells (MCF-7 cells). In other labs, cordycepin has been …