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Articles 391 - 420 of 518
Full-Text Articles in Nursing
Marfan Syndrome In Athletes, Chelsey Hastings
Marfan Syndrome In Athletes, Chelsey Hastings
Nursing Student Class Projects (Formerly MSN)
Genetic disorders are widely misunderstood in our society and can lead to early mortality. Marfan syndrome (MFS) is a genetic disorder that affects connective tissue (Harris, Croce, & Tian, 2014). Antoine Marfan, a French pediatrician, first described this disease in 1896 (Elshershari & Harris, 2014). MFS can manifest in several different organ systems. The cardiovascular complications of aortic dilation and dissection often account for the morbidity associated with this disease (Harris et al., 2014). Understanding the inheritance, pathophysiology, and treatment of MFS is important for the advanced practice nurse (APN). Prevalence of the disease is approximately two per 10,000 individuals, …
Granulomatosis With Polyangiitis (Wegner’S) : Often Mistaken For Tuberculosis, Dawn Palumbo
Granulomatosis With Polyangiitis (Wegner’S) : Often Mistaken For Tuberculosis, Dawn Palumbo
Nursing Student Class Projects (Formerly MSN)
The exact cause of GPA has yet to be identified. Dinić et al. (2013) defines GPA/WG as “anti-neutrophil cytoplasmic antibodies (ANCAs)- associated systemic vasculitis of unknown etiology” (p. 887). According to Alam, Dastider, Ahmed, and Rabbani (2012) both cellular and humoral immunity are thought to be involved in the pathogenesis of wegener’s granulomatosis. “ The initial pathologic lesion is granuloma believed to be caused by cellular immune process. The strong association on C-ANCA with this disease suggests the role of humoral immunity” (Alam et al., 2014, p. 98). Huang et al. (2013) suggest, “The main pathological features of limited Wegeners’ …
Basal Cell Carcinoma—A Preventable Disease, Jamie Weaver
Basal Cell Carcinoma—A Preventable Disease, Jamie Weaver
Nursing Student Class Projects (Formerly MSN)
Basal cell carcinoma (BCC) is a nonmelanoma skin cancer. According to the Skin Cancer Foundation, “BCC is the most frequently occurring form of all skin cancers. More than one out of every three new cancers is a skin cancer, and the vast majority are BCC’s” (www.skincancer.org). Exposure to ultraviolet (UV) rays is one of the main risk factors in developing a BCC. People with a lighter skin tone are at a higher risk of developing a BCC than those with a darker skin tone.
Nash: Non-Alcoholic Steatohepatitis, Jennifer Heck
Nash: Non-Alcoholic Steatohepatitis, Jennifer Heck
Nursing Student Class Projects (Formerly MSN)
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which refers to the presence of hepatic steatosis without significant intake of alcohol. Non-alcoholic fatty liver disease develops in a variety of forms from reversible simple steatosis to non-alcoholic steatohepatitis (NASH), which if left unchecked can progress to liver fibrosis, cirrhosis and even develop into hepatocellular carcinoma (Mells et al., 2014). NAFLD is thought to be nonthreatening, but with progression over several years could lead to NASH. A strong link between obesity and NASH has been shown. In addition to obesity, insulin resistance (type II diabetes mellitus), and hyperlipidemia all …
Non-Valvular Atrial Fibrillation And Stroke: Novel Oral Anticoagulants Versus Vitamin K Antagonists, Kathryn A. Viglietta
Non-Valvular Atrial Fibrillation And Stroke: Novel Oral Anticoagulants Versus Vitamin K Antagonists, Kathryn A. Viglietta
Nursing Student Class Projects (Formerly MSN)
Atrial fibrillation (afib) is the most common sustained cardiac arrhythmia and second most common cardiovascular condition in adults in the United States (Zarraga & Kron, 2012). •2.2 million affected, increases risk of stroke 4 to 6 times (National Institute of Neurological Disorders and Stroke [NINDS], 2015). •Vitamin K antagonists (VKAs) have been mainstay of therapy for over 60 years (King, Holley& Moores, 2013). •Limitations with VKAs such as variability in response, need for frequent lab draws, food and drug interactions which decrease patients adherence and under prescribing by physicians (Halperin & Goyette, 2012). •Novel oral anticoagulants (NOACs) have been approved …
Gout, Lorrie Listebarger
Gout, Lorrie Listebarger
Nursing Student Class Projects (Formerly MSN)
Gout is a syndrome caused by an inflammatory response creating an over production of uric acid increasing uric acid levels in the blood and body fluids. Gout is defined as a disorder resulting from tissue deposition of MSU crystals (in joints, bursae, bone, and certain other soft tissues, such as ligaments, tendons and occasionally, skin) and/or crystallization of uric acid within the renal collecting system (tubules and renal pelvis) that typically occurs in acid urine” (Terkeltaub & Edwards, 2013, p. 20). Gout is among the oldest diseases affecting approximately 3.9% of adults in America (Terkeltaub & Edwards, 2013, p. xv). …
Diabetic Ketoacidosis, Mario Bianconi
Diabetic Ketoacidosis, Mario Bianconi
Nursing Student Class Projects (Formerly MSN)
According to “Statistics About Diabetes” (2014), in 2012, 29.1 million Americans, or 9.3% of the population, had diabetes. Additionally, of the 29.1 million, 21 million of the population were diagnosed, and 8.1 million were undiagnosed. With such a high prevalence, it is imperative that the hospital nurse is aware not only how to treat diabetes, but also how to look for complications of diabetes. One of the severe complications of diabetes is Diabetic Ketoacidosis, or DKA. DKA occurs as a result of prolonged untreated diabetes. It is the result of the body not being able to produce, or use, insulin …
Neurological, Nutritional And Cognitive Effects Of Environmental Lead Exposure In Infants And Children, Melissa Bianchi
Neurological, Nutritional And Cognitive Effects Of Environmental Lead Exposure In Infants And Children, Melissa Bianchi
Nursing Student Class Projects (Formerly MSN)
Environmental lead exposure is a pertinent public health risk that affects our rural population in Wyandot County, Ohio. Children exposed to lead hazards through toys, home remodeling and contaminated soil and water are at a greater risk for developing neurological, cognitive and behavioral issues than are children not exposed to lead (Cecil et al., 2011). Wyandot County parents are not adequately educated on the risks and consequences of elevated blood lead levels in their children. As a child advocate and director of the Women, Infant and Children program for Wyandot County there is an obligation to educate and inform parents …
Neuroleptic Malignant Syndrome: A Pathophysicological Dilemma, Samantha Davis
Neuroleptic Malignant Syndrome: A Pathophysicological Dilemma, Samantha Davis
Nursing Student Class Projects (Formerly MSN)
Neuroleptic malignant syndrome (NMS) is a rare disease occurring from an adverse reaction to anti-psychotic use. The diagnosis and predictability of the disease is extremely difficult as it mimics other syndromes (Margetić & Aukst-Margetić, 2010). The disease onset can occur when initiating medications, escalating doses, or adding an adjunctive anti-psychotic to the regimen. Although causing the unpredictability, the disease can occur at any dose (Paul, Michael, John, & Lenox, 2012). Further increasing the difficulty of diagnostics, signs and symptoms are very wide spread. The Diagnostic and Statistical Manual of Mental Disorders created a tool to assist in the clinical setting; …
Raynaud’S Phenomenon, Sarah Gasper
Raynaud’S Phenomenon, Sarah Gasper
Nursing Student Class Projects (Formerly MSN)
Raynaud’s phenomenon (RP) is a widely prevalent clinical disorder commonly seen in outpatient settings. It is characterized by episodic vasospastic attacks of the digital arteries and arterioles that limit blood flow to the extremities, causing severe pain. Temperature changes and stress are the primary triggers that exacerbate this disease. The classic biphasic color changes of RP are pallor, cyanosis, and erythema and commonly affect the fingers and toes and more rarely, the nose, nipples, ears, lips, and penis. RP is divided into subcategories. Primary Raynaud’s phenomenon (PRP) is when no underlying medical disease exists and the condition happens spontaneously. It …
Polycystic Ovarian Syndrome, Tameka Todd
Polycystic Ovarian Syndrome, Tameka Todd
Nursing Student Class Projects (Formerly MSN)
The main goal of this project was to educate peers on the pathophysiology of a disease or disorder of choice. The topic to be discussed is Polycystic Ovarian Syndrome (PCOS). This topic was chosen based on personal interest in women’s health issues. PCOS is a metabolic disease affecting 5-10 percent of women of childbearing age (Morgan, 2013). Characteristics of PCOS include enlarged ovaries consisting of multiple small cysts surrounding the outer ovary, with unknown cause (Morgan, 2013). Leading to the ovaries producing an increased amount of androgen (male hormones) (Morgan, 2013).
Multiple Sclerosis And The Implications Of Anesthesia, Timothy B. Maiden
Multiple Sclerosis And The Implications Of Anesthesia, Timothy B. Maiden
Nursing Student Class Projects (Formerly MSN)
Multiple Sclerosis (MS) is an autoimmune process characterized by inflammation and demyelination of axons in the brain and spinal cord (Schneider, 2005). According to Maclean (2010), MS is one of the most common debilitating neurological disorders in young adults. My intent of this research project is to explain the pathophysiological process and become familiar with the implications of anesthesia related to MS. This research will enable me to prepare a safe, individualized anesthetic plan, taking all essential precautions when caring for a patient with multiple sclerosis.
Chagas Disease: Immigrating Into The United States, Angela Metzger
Chagas Disease: Immigrating Into The United States, Angela Metzger
Nursing Student Class Projects (Formerly MSN)
Chagas Disease is starting to make a profound entrance into our communities within the United States. The influx of the immigrant population is the principal cause of the accumulation in the number of reported cases. (Center for Disease Control and Prevention, 2014). The Trypanosoma cruzi is a parasite that causes Chagas disease. The triatomine blood sucking insect enjoys the mucosal membranes of their pray, both humans and animals. The most common regions of the penetrating bite are the conjunctiva of the eye or around the mouth. It is through the feces of the vector entering the inoculation site that initiates …
Exploring The Pathophysiological Concepts Of Ebola Virus, Andrew T. Wasson
Exploring The Pathophysiological Concepts Of Ebola Virus, Andrew T. Wasson
Nursing Student Class Projects (Formerly MSN)
The Ebola virus is a member of the filoviridae family. Five distinctive species of ebolavirus have been identified, four of which are known to cause disease in humans (Martines, Ng, Greer, Rollin, and Zaki, 2014). The specific species known to cause disease in humans are Zaire, Sudan, Ivory Coast, and Bundibugyo (Bray & Chertow, 2014). Bah et al. (2015) report that the Zaire ebolavirus (EBOV) was the cause of the most recent West African outbreak and carries the highest human mortality rate among the five known species, with up to 90% of cases being fatal. Ebola is a filamentous, enveloped, …
Maggot Therapy For Treating Diabetic Foot Ulcers, Amber Nikolaus
Maggot Therapy For Treating Diabetic Foot Ulcers, Amber Nikolaus
Nursing Student Class Projects (Formerly MSN)
Diabetes mellitus, Type 1 and Type 2, are associated with numerous debilitating consequences. One of the most common and serious complication is diabetic foot ulcers (DFU) (Baltzis, Elftheriadou, and Veves, 2014, p.817). DFUs are “caused by loss of glycemic control, peripheral neuropathy, peripheral vascular disease, and immunosuppression” and account for greater than 80,000 amputations per year in the United States (Aumiller & Dollahite, 2015, p.28). Approximately 15% of people with diabetes have diabetic foot ulcers (Aumiller & Dollahite, 2015, p.28) and studies demonstrate that 45% to 55% of patients presenting with neuropathic and ischemic diabetic foot ulcers will die within …
Chikungunya Virus: More Than A Mosquito Bite, Abigail Shaw
Chikungunya Virus: More Than A Mosquito Bite, Abigail Shaw
Nursing Student Class Projects (Formerly MSN)
Chikungunya fever is a viral infection caused by the Chikungunya virus (CHIKV). Although seldom fatal, CHIKV causes high fevers, polyarthralgia, and rash. The mosquito-borne virus has spread rapidly in the last ten years, causing over three million cases of CHIKV worldwide (Powers, 2015). The recent outbreak initiated in Africa and the islands of the Indian Ocean in 2004 has quickly spread to Asia, Europe and the Americas (CDC, 2015). According to the CDC (2015), until 2014, cases in the United States had only been linked to foreign travel outside of the Americas. As the outbreak has grown, cases of local …
Identifying Acute Organ Dysfunction As A Marker Of Severe Sepsis, Daniell Mcsweeney
Identifying Acute Organ Dysfunction As A Marker Of Severe Sepsis, Daniell Mcsweeney
Nursing Student Class Projects (Formerly MSN)
The current definition of sepsis is suspected or documented infection plus at least one systemic manifestation of infection. Severe sepsis has been defined as sepsis plus evidence of organ dysfunction. Identifying acute organ dysfunction is a marker of severe sepsis. This topic was chosen after witnessing a number a patients fall into septic shock before severe sepsis was diagnosed and treatment initiated. Diagnosis of severe sepsis is important for specific protocol to be implemented in a timely fashion. The current differentiation between sepsis and severe sepsis is evidence of organ dysfunction. There are many examples of organ dysfunction that are …
Raising Awareness: Polycystic Kidney Disease, Dana Dendinger
Raising Awareness: Polycystic Kidney Disease, Dana Dendinger
Nursing Student Class Projects (Formerly MSN)
A young male patient was recently admitted to the intensive care unit at a local hospital with hypertensive urgency and acute renal failure of unknown etiology. A renal ultrasound showed polycystic kidneys and upon further investigation, it was discovered that the patient’s mother passed away last year from end stage renal failure related to polycystic kidney disease (PKD). The aforementioned case and the recent study into inherited disorders are what prompted further investigation into PKD. Liebau and Serra (2013) explain that “inherited cystic kidney diseases, autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), are the …
Insulin Resistance Due To Obesity, Chasity Crist
Insulin Resistance Due To Obesity, Chasity Crist
Nursing Student Class Projects (Formerly MSN)
Diabetes is defined as a common metabolic disorder where hyperglycemia or elevated glucose levels are prevalent (Shah & Vella, 2014). The most common form of diabetes is type two diabetes (T2DM) and effects around 9.3% of the population in the United States (Cornell, 2015, p. 631). The pathophysiology of this disease includes involvement from the pancreas, liver, skeletal muscle, adipose tissue, gastrointestinal tract, brain, and kidneys. Hyperglycemia is high blood sugar levels that effects multiple organs (Rymaszewski & Breakwell, 2013). Protocols are developed to allow nurses to identify and treat hyper/hypoglycemia. Patient education is a direct impact of the long …
Juvenile Myoclonic Epilepsy, April Britton
Juvenile Myoclonic Epilepsy, April Britton
Nursing Student Class Projects (Formerly MSN)
Juvenile myoclonic epilepsy (JME) is one of the most common epilepsies of childhood (Korff, Nordli, & Eichler, 2014). JME typically occurs in otherwise healthy teenagers, and is characterized by one or more of the following seizure types: myoclonic jerks, generalized tonic clonic seizures, and absence seizures (Korff, Nordli, & Eichler, 2014). JME is thought to have genetically mediated factors (Park, Shahid, & Jammoul, 2015). JME is considered to be gender equal (Korff, Nordli, & Eichler, 2014). Most JME patients are diagnosed between 12 and 18 years of age (Korff, Nordli, & Eichler, 2014). Triggers linked to onset of seizure activity …
Thrombotic Thrombocytopenia Purpura, Ann Oliva
Thrombotic Thrombocytopenia Purpura, Ann Oliva
Nursing Student Class Projects (Formerly MSN)
Patients with Thrombotic Thrombocytopenia Purpura, or TTP, are often times seen in the emergency department and subsequently admitted to the inpatient or the critical care unit. The problems that TTP patients can present with vary greatly and astute nursing assessment plus knowledge of the pathophysiology behind the diagnosis is vital to deliver excellent nursing care. Thrombotic Thrombocytopenia Purpura or TTP is a rare but potentially fatal condition that occurs as result of decreased levels of ADAMTS-13, a cleaving protease for von Willebrand factor (vWF), which causes platelet aggregation and microvascular thrombi and subsequent end-organ damage, along with thrombocytopenia, hemolytic anemia, …
Nonimmune Hydrops Fetalis, Heather Walker
Nonimmune Hydrops Fetalis, Heather Walker
Nursing Student Class Projects (Formerly MSN)
Hydrops fetalis is an excessive accumulation of fluid within the fetal extravascular compartments and body cavities generally characterized by: •placental enlargement •ascites •pericardial effusions •pleural effusions (Bellini, 2014, p. 1082). Nonimmune hydrops fetalis (NIHF) develops as a result of one or more nonimmune factors, distinguishing it from immune hydrops fetalis that results from a maternal antigen-body fetal antigen-mediated red blood cell hemolysis (Randenberg, 2010, p. 281).
Malignant Hyperthermia, Hailey Jones
Malignant Hyperthermia, Hailey Jones
Nursing Student Class Projects (Formerly MSN)
According to the Malignant Hyperthermia Association of the United States (2015), “Malignant hyperthermia (MH) is a potentially fatal, inherited disorder usually associated with the administration of certain general anesthetics and/or the drug succinylcholine.” Malignant hyperthermia has been presented to me during hospital skills days over the past year due to the increased need for knowledge regarding this topic. I choose this topic because I find it interesting due to the fact that I could encounter this in the remainder of my days in the intensive care unit, but most importantly because I will be dealing with these drugs on a …
Type Ii Diabetes And Its Treatment, Gregory Mountain
Type Ii Diabetes And Its Treatment, Gregory Mountain
Nursing Student Class Projects (Formerly MSN)
Approximately 28.9 million Americans have been diagnosed with type II diabetes (Jia-Haur Hu, Lin, Miller, Nguyen, & Nguyen, 2014). It is a disease that can cause or potentiate numerous comorbidities that negatively affects multiple body systems if left untreated (Jia-Haur Hu, et al., 2014). In 2012, the total estimated cost for treatment of type II diabetes in America was an astronomical $245 billion (Jia-Haur Hu, et al., 2014). Type II diabetes is a result of many cellular processes that lead to insulin resistance resulting in increased blood glucose levels (Jia-Haur Hu, et al., 2014). Treatments for type II diabetes include …
Acute Immune Thrombocytopenia Purpura, Erin Woodworth
Acute Immune Thrombocytopenia Purpura, Erin Woodworth
Nursing Student Class Projects (Formerly MSN)
Immune thrombocytopenic purpura (ITP), formerly known as idiopathic thrombocytopenic purpura, is a relatively rare, but potentially life threatening autoimmune disorder that involves the destruction of platelets by autoantibodies. The resultant decreased platelet count leaves the patient at risk for excessive bruising and bleeding (Hunt, 2010). ITP can occur in both adults and children, and also occurs as an acute or chronic disorder. It is thought that the cause of acute ITP may differ from that of chronic ITP, however, the underlying disease processes that occur are very similar (Johnsen, 2012). Acute ITP, the most common form of the disease, most …
Malignant Hyperthermia: A Clinical Crisis, Eric Reing
Malignant Hyperthermia: A Clinical Crisis, Eric Reing
Nursing Student Class Projects (Formerly MSN)
Malignant hyperthermia, though uncommon, is a serious and life threatening condition. Malignant hyperthermia is an autosomal dominant disorder that affects skeletal muscle. It can be caused by various general anesthetic agents like succinylcholine and several inhaled anesthetics. Malignant hyperthermia is a relevant topic to certified registered nurse anesthetists due to the potentially fatal result if not recognized and treated promptly. In understanding the pathophysiology, risk factors, signs and symptoms, epidemiology, and current treatments the health care provider can help to prevent complications due to this disorder (Nagelhout, 2014).
Gout As A Significant Risk Factor For Cardiovascular Disease: A Case Study, Emily Leonhard
Gout As A Significant Risk Factor For Cardiovascular Disease: A Case Study, Emily Leonhard
Nursing Student Class Projects (Formerly MSN)
Gout, an inflammatory arthritis caused by elevated serum uric acid levels, is emerging as a significant risk factor for cardiovascular disease (CVD). Recently, a nurse practitioner (NP) was caring for a patient who was suffering from a particularly severe gout attack while being treated in the ICU for new onset Atrial Fibrillation. The patient reported that he had never had an attack this severe before. He asked the NP if his history of gout could be related to his recent heart problems. The nurse practitioner, in order to answer the patient’s question, spent time researching the disease process of gout, …
Antithyroid Drug-Induced Agranulocytosis, Elizabeth Spears
Antithyroid Drug-Induced Agranulocytosis, Elizabeth Spears
Nursing Student Class Projects (Formerly MSN)
We live in a culture that is busy and constantly on the go. With little time to spare, often symptoms of an alteration in bodily function are pushed to the side and attribute to the stress of everyday life. With symptoms including nausea, fatigue, weight loss, nervousness, and irritability, one may be more inclined to disregard these symptoms, only to attribute them to effects of a busy lifestyle. The presentation of the previously listed symptoms can formulate a medical diagnosis of hyperthyroidism. According to the American Thyroid Association, 20 million Americans will develop some type of alteration in thyroid function …
Pathological Jaundice, Dianna Contosta
Pathological Jaundice, Dianna Contosta
Nursing Student Class Projects (Formerly MSN)
Neonatal jaundice is a common condition present in infants after birth. It is caused by elevated bilirubin in the blood. It can affect up to 84% of term infants and is one of the most common cause for hospital readmission for the neonatal department (Muchowski, 2014). It typically appears within 24 hours of life and is normally present in otherwise healthy newborns. Physiologic jaundice, also known as unconjugated bilirubin, is a normal process that happens in neonates because the hepatic system is not matured yet (Kirk, 2008). Majority of the time physiologic jaundice resolves on its own. Pathological jaundice, also …
Deep Venous Thrombosis In Surgical Orthopedic Patients, Kelly Marsh
Deep Venous Thrombosis In Surgical Orthopedic Patients, Kelly Marsh
Nursing Student Class Projects (Formerly MSN)
•The term venous thromboembolism (VTE) is defined as a syndrome that collectively comprises both deep vein thrombosis (DVT) and pulmonary embolism (PE). Each year approximately 350,000-900,000 people in the United States develop VTE and approximately 100,000 people die according to this cause (Streiff et al., 2014). Unfortunately, the reoccurrence rate for VTE remains very high, with an estimated risk of 10%-30% of VTE patients will develop another VTE within five years of the first incident (Streiff et al., 2014). •Deep vein thrombosis (DVT) is blood clot that forms in a large vein, usually in areas of slow blood flow such …