Substance Abuse and Addiction Commons^™

Reducing Medical Errors For Patients With Substance Use Disorders With A Medical Information Card, Michael V. Hughes

Doctoral Dissertations & Projects

Background

Approximately 98,000 Americans perish annually due to medical errors and adverse events associated with the limited access to or incomplete pertinent patient health information (Centers for Disease Control and Prevention [CDC], 2022; Obrien et al., 2021). Pertinent patient health information includes patients’ allergies, current medications, current medical diagnosis, blood type, insurance, and emergency contact. The purpose of this project was to examine the efficacy in using File of Life cards in reducing medical errors among patients with substance use disorders (SUDs), and the perception of patients and healthcare providers ease of use, satisfaction of using the File of Life …

Designing A Work-Life Balance Learning Module For Cal Poly Construction Management Department, Alex Jones

Construction Management

The construction industry is known to create a highly stressful work environment given its unpredictability and mental/time demanding nature, which creates challenges for professionals to maintain a healthy work-life balance. This senior project aims to research and identify the key areas that foster this stress and propose a learning module for the Cal Poly Construction Management Department to implement into class curriculum. Having this learning module taught to students will raise awareness of the topic for future industry professionals and equip them with the tools to maintain a healthy equilibrium between their work demands and personal life. The learning module …

Characterization Of Differential Rearing And Sex On 5-Ht2ar Receptor Activation, Kelsey Lowe

Theses/Capstones/Creative Projects

The prevalence of substance use disorders (SUDs) continues to rise while the number of medications to combat this deadly disorder remains stagnant. Entirely new thinking about what exemplifies a possible therapeutic is needed. Hallucinogens are continually being studied more as possible treatments for many psychological conditions, including SUDs. Classic hallucinogens engage many serotonin and monoamine systems, but the hallucinogenic effects are driven by serotonin 5-HT_2A receptor (5-HT_2AR) activation. Forced social isolation induces chronic stress, increases 5-HT_2AR expression in the cortex and have been suggested to play a role in the comorbidity between stress, maladaptive coping, …

Art And Rehabilitation: An Analysis Of Art In The Treatment Of Individuals Recovering From Substance Use Disorders, Cheyenne Weis

Theses/Capstones/Creative Projects

Substance use has been a huge problem in the United States for a long time. Typically, techniques such as behavioral therapies or 12-Step Programs are used regarding treatment for those trying to recover from substance use disorders. While these treatment options are useful for many people, it is also important to look at nonnormative options for treatment to help the greatest number of people. One of these treatment options is the use of art, either as art therapy or as therapeutic art-making. Previous research on art therapy and people with substance use disorders demonstrates that there are many benefits of …

“I Know My Body Better Than Anyone Else” Perspectives Of People Who Inject Drugs On Antimicrobial Treatment Decision Making For Serious Infections, Amy Eckland, Michael Kohut Phd, Henry Stoddard, Debra Burris, Frank Chessa, Monica Sikka, Daniel Solomon, Colleen Kershaw, Ellen Eaton, Rebecca N. Hutchinson, Peter Friedmann, Thomas Stopka, Kathleen Fairfield, Kinna Thakarar

Costas T. Lambrew Research Retreat 2023

Introduction:

• Few studies have examined the perspectives of patients with lived experience regarding outpatient treatment options for injection drug use (IDU) associated infections.

• We sought to better understand the perspectives of both community partners with lived experience who work with people who inject drugs (PWID) and hospitalized patients with IDU-associated infections on shared treatment decision making.

Support For Social Workers Treating Adolescent Substance Abusers, Monica Delucia, Kethura Solano

Electronic Theses, Projects, and Dissertations

This study examines the barriers social workers experience when working with adolescent substance users. Research has not fully explored if intervention techniques are effective or suggest other approaches that may support substance use disorder professionals including supervisor support, training, and intervention. The purpose of this study was to evaluate if social workers who provide interventions to adolescent substance users have the adequate resources to be successful in their field. The literature review provides a better understanding of the common themes social workers experience when working with adolescent substance users.

This study used a qualitative design and interviewed 8 professional social …

County Characteristics And Opioid Mortality Rates In The United States, Baksun Sung

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Opioid overdose deaths are not equally distributed across the United States. While some areas have a less severe problem with opioid abuse, others face serious challenges, which are affected by various social factors. To address that question, in Chapter 1, I investigate how opioid mortality trends differ according to opioid types, race, and region to identify susceptible populations and areas. In Chapter 1, I contend that synthetic opioid is a main trigger for the current opioid epidemic and that the epidemic is concentrated among blacks and in the Eastern United States. Next, the following studies examine how varying social vulnerabilities …

Surviving The Stigma: Incorporating Mental Health Literacy To Increase Help-Seeking In California First Responders, Yvonne C. Newson

Master's Projects and Capstones

First responders are at risk of developing mental health problems due to repeated exposure to traumatic incidents, increasing their chance of developing Post Traumatic Stress Disorder, substance abuse, suicidal ideation, and suicide. Unfortunately, first responders do not recognize that they may have a mental illness and are reluctant to seek help. This paper will discuss the prevalence of mental health problems among first responders and the barriers to their help-seeking. These barriers include the stigma around mental illness within the culture, the assessability of professional help, and the lack of mental health literacy regarding their well-being. Further discussion will focus …

One Immune System Plays Many Parts: The Dynamic Role Of The Immune System In Chronic Pain And Opioid Pharmacology, Sanam Mustafa, Juliana E Bajic, Benjamin Barry, Samuel Evans, Kariel R Siemens, Mark R Hutchinson, Peter M Grace

Faculty, Staff and Student Publications

The transition from acute to chronic pain is an ongoing major problem for individuals, society and healthcare systems around the world. It is clear chronic pain is a complex multidimensional biological challenge plagued with difficulties in pain management, specifically opioid use. In recent years the role of the immune system in chronic pain and opioid pharmacology has come to the forefront. As a highly dynamic and versatile network of cells, tissues and organs, the immune system is perfectly positioned at the microscale level to alter nociception and drive structural adaptations that underpin chronic pain and opioid use. In this review, …

Opioid-Related Mortality: Dynamic Temporal And Spatial Trends By Drug Type And Demographic Subpopulations, Massachusetts, 2005–2021, Thomas J Stopka, Marc R Larochelle, Xiaona Li, Dana Bernson, Wenjun Li, Leland K Ackerson, Ric Bayly, Olaf Dammann, Cici Bauer

Faculty, Staff and Student Publications

BACKGROUND: Fatal opioid-related overdoses (OOD) present significant public health challenges. Intuitive and replicable analytical approaches are needed to inform targeted public health responses.

METHODS: We obtained fatal OOD data for 2005-2021 from the Massachusetts Registry of Vital Records and Statistics. We conducted heatmap analyses to assess trends in fatal OOD rates per 100,000 residents, visualizing rates by death year and decedent age at one-year intervals, stratifying by race/ethnicity, sex, rurality, and involved substances. We calculated Getis-Ord Gi* statistics to identify spatial clusters of OOD rates.

RESULTS: Among 20,774 fatal OODs, rates were higher among males, and highly variable by race/ethnicity, …

Perceived Negative Political Climate Among Hispanic/Latino Adolescents Before And After The 2020 Us Presidential Election: Associations With Internalizing Symptoms And Substance Use, Pablo Montero-Zamora, Saskia R Vos, Jennifer B Unger, Ingrid Zeledon, Ryan Lee, Daniel W Soto, Eric C Brown, Maria Duque, Maria Fernanda Garcia, Carolina Scaramutti, Beyhan Ertanir, Seth J Schwartz

Faculty, Staff and Student Publications

The political climate often changes following the installment of a new president. This volatility presents opportunities for examining how elections might affect vulnerable subgroups such as Hispanic/Latino (HL) adolescents. The present study explored the perception of negative political climate among HL adolescents before and after the 2020 U.S. presidential election and its association with internalizing symptoms and substance use. We conducted the study in Los Angeles and Miami between 2020-2021, with a sample of 304 HL adolescents (Females = 60.8%), aged 15.3 years on average. Participants completed measures of negative political climate (pre- post-election) and measures of depressive symptoms, anxiety, …

A Retrospective Comparison Of The Effectiveness Of Buprenorphine Versus Baclofen For Acute Opioid Withdrawal, Matthew Hermenau, Benton Stamper, Kitty Leung, Raymond Pomm, Christina Guerrier, Joseph Cammilleri, Brittany Johnson

HCA Healthcare Journal of Medicine

Background

A significant impediment to opioid cessation or dose reduction is mitigating withdrawal severity that has been shown to affect the course of opioid dependence. Current guidelines recommend the use of buprenorphine and methadone over alpha-2 adrenergic agonists. Baclofen, a GABA-B agonist, has promising results as an adjunct agent for opioid withdrawal but has not been compared to buprenorphine. This study compared the ability of buprenorphine and baclofen to mitigate acute opioid withdrawal.

Methods

This was a single-center, retrospective chart review of 63 patients with diagnosed opioid use disorder that received scheduled buprenorphine or baclofen for 3 days, in addition …

Mental Health In M*A*S*H: An Analysis Of The Changing Portrayal Of Mental Health Topics In The 1970s And Early 1980s, Lyndsey Clark

Departmental Honors & Graduate Capstone Projects

This paper studies all eleven seasons of the hit television show M*A*S*H (1972-1973) and examines how the portrayal of mental health changed in the show’s plotlines in response to changing guidelines and mental health policy in the 1970s and early 1980s. This study focuses on the association of mental illness with homosexuality, the changes made to the American Psychological Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM) in the 1970s and early 1980s, the rise and fall of mental health policies from the Kennedy Administration to the Reagan Administration, and the portrayal of several pertinent mental conditions, such as …

Augmenting Project Echo For Opioid Use Disorder With Data-Informed Quality Improvement, Owen B. Murray, Marcy A. Doyle, Bethany M. Mcleman, Lisa A. Marsch, Elizabeth C. Saunders, Katherine Cox, Delitha Watts, Jeanne Ryer

Faculty Publications

Background

National opioid-related overdose fatalities totaled 650,000 from 1999 to 2021. Some of the highest rates occurred in New Hampshire, where 40% of the population lives rurally. Medications for opioid use disorder (MOUD; methadone, buprenorphine, and naltrexone) have demonstrated effectiveness in reducing opioid overdose and mortality. Methadone access barriers disproportionally impact rural areas and naltrexone uptake has been limited. Buprenorphine availability has increased and relaxed regulations reduces barriers in general medical settings common in rural areas. Barriers to prescribing buprenorphine include lack of confidence, inadequate training, and lack of access to experts. To address these barriers, learning collaboratives have trained …

Prevention And Education In Medication Assisted Treatment Facilities, Lindsey Mccartt

Epsilon Sigma at-Large Research Conference

Introduction and Background: Between 1999 and 2014 the number of patients in the labor and delivery that were on medication for opioid use disorder (MOUD) quadrupled. The rate of unintended pregnancies in pregnant patients of mOUD is at a tremendous high due to inconsistencies in the use of reliable contraception in this population.

Purpose Statement: To reduce the number of unintended pregnancies and infants born with neonatal abstinence syndrome there is a need for prevention and required education for men and women in medication-assisted facilities.

Literature Review: Twenty research studies were reviewed and evaluated. These articles were …

Assessing The Involvement Of Projections From The Prelimbic Prefrontal Cortex To The Paraventricular Nucleus Of The Thalamus In Cocaine Withdrawal-Induced Anxiety, Clinton Coelho

MUSC Theses and Dissertations

Withdrawal from cocaine induces an immediate and powerful negative affective state which is characterized by feelings of agitation and anxiety in humans and anxiety-like behaviors in rodents. It has been hypothesized that the anxiogenic effects associated with cocaine withdrawal play a major role in continued cocaine use and drive relapse to cocaine seeking. The prelimbic (PL) medial prefrontal cortex is not only involved in the processing and regulation of negative emotions such as anxiety but also mediates relapse to cocaine-seeking. Subcortical hubs of the reward system that receive projections from the PL neurons are known to be dysregulated during different …

Computational Design And Molecular Modeling Of Morphine Derivatives For Preferential Binding In Inflamed Tissue, Makena Augenstein, Nayiri Alexander, Matthew Gartner

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The opioid epidemic has impacted over 10 million Americans in 2019. Opioids, like morphine, bind non-selectively in both peripheral tissue, leading to effective pain relief, and central tissue, resulting in dangerous side effects and addiction. The inflamed conditions of injured tissues have a lower pH (pH = 6–6.5) environment than healthy tissue (pH = 7.4). We aim to design a morphine derivative that binds selectively within inflamed tissue using molecular extension and dissection techniques. Morphine binds to the μ-opioid receptor (MOR) when the biochemically active amine group is protonated. Fluorination of a β-carbon from the tertiary amine group led to …

Benefits Of Rooming-In On Infants With Neonatal Opioid Withdrawal Syndrome, Emma Ricioli

Nursing | Student Research Posters

Neonatal opioid withdrawal syndrome (NOWS) is a significant public health concern, affecting infants born to mothers who use opioids during pregnancy. Those exposed in-utero exhibit numerous signs of withdrawal after delivery including tremors, gastrointestinal distress, inconsolability, and poor feeding. Typical treatment for infants suffering from NOWS included direct admission to the neonatal intensive care unit (NICU) for close observation and pharmacological interventions. However, NICU stays can interfere with bonding and breastfeeding. They can also lead to increased lengths of stay, higher costs, and more invasive pharmacological treatments. These infants typically do not have any other concerning health issues besides NOWS …

Adolescent Use And Co-Use Of Tobacco And Cannabis In California: The Roles Of Local Policy And Density Of Tobacco, Vape, And Cannabis Retailers Around Schools, Georgiana Bostean, Anton M. Palma, Alison A. Padon, Erik Linstead, Joni Ricks-Oddie, Jason A. Douglas, Jennifer B. Unger

Sociology Faculty Articles and Research

Adolescent tobacco use (particularly vaping) and co-use of cannabis and tobacco have increased, leading some jurisdictions to implement policies intended to reduce youth access to these products; however, their impacts remain unclear. We examine associations between local policy, density of tobacco, vape, and cannabis retailers around schools, and adolescent use and co-use of tobacco/vape and cannabis.

We combined 2018 statewide California (US) data on: (a) jurisdiction-level policies related to tobacco and cannabis retail environments, (b) jurisdiction-level sociodemographic composition, (c) retailer locations (tobacco, vape, and cannabis shops), and (d) survey data on 534,176 middle and high school students (California Healthy Kids …

The Need For Sharps Boxes To Be Offered In The Hospital Setting For People Who Use Substances: Removing Sharps Boxes Puts All Of Us At Risk., Cheryl Forchuk, Michael Silverman, Abraham Rudnick, Jonathan Serrato, Brenna Schmitt, Leanne Scott

Nursing Publications

INTRODUCTION: Substance use can occur in the hospital setting among people with substance use disorder, including intravenous use. However, the provision of sharps boxes is not typically offered in Canadian hospitals. This study set out to explore the current issues due to the lack of harm reduction in the hospital setting.

METHOD: Thirty-one health care professionals participated in virtual one-to-one interviews and focus groups regarding harm reduction in hospital. The issue of sharps box removal was highlighted as a concern. A secondary ethnographic thematic analysis explored this theme in more detail. A scoping review of the literature observed additional considerations. …

Treating Opioid Use Disorder: One Shot At A Time, Shelly Haferkamp, Michael P. Kinney, Daniel Yang, Lindsey Cunningham, Anna Davey, Amy G Burns

View All Graduate Medical Education Content

No abstract provided.

Benzodiazepine-Minimizing Protocol For Alcohol Withdrawal: A Comparative Analysis, Jennifer Gaston, Hsin-Fang Li, Emily J Cox, Caitlin Klamper, John F Wurzel

View All Graduate Medical Education Content

No abstract provided.

How The United States Can Improve The Prevention And Treatment Of Substance Abuse Disorders, Kimberly E. Combs

Classical Conversations

Over thirty million people worldwide suffer from diagnosed drug-use disorders. In the United States alone, the Substance Abuse and Mental Health Services Administration found in the 2020 National Survey of Drug Use and Health (NSDUH) that of people aged 12 or older, over 40 million reported struggling with substance abuse at some point in their life. Alarming statistics suggest that rates of drug abuse continue to rise worldwide. Drug use is a recognized epidemic in the United States, and it is far from a recent issue. Health professionals, government officials, and researchers have been trying to solve the problem for …

Model Perencanaan Strategis Dalam Service Organization : Sebuah Kajian Literatur, Rakhmiana, Johanna Debora Imelda

Jurnal Ilmu Kesejahteraan Sosial

In Indonesia, several types of HSOs include government organizations, private organizations, and non-profit organizations. Strategic planning is crucial for HSOs as it helps them to map their direction and goals, manage their resources, identify opportunities and challenges, coordinate their activities, and measure and evaluate their performance. To assist in strategic planning, various mapping models can be used. One of the models that can be used is Scenario- Based Road Mapping (SBRM). This research is a literature review that discusses different strategic planning models for HSOs, which can help organizations formulate more effective and adaptive strategies. These models can help HSOs …

Implementasi Kebijakan Bantuan Pangan Non Tunai Dalam Rangka Pengatasan Kemiskinan Di Era Covid - 19, Haura Ariesta, Fentiny Nugroho

Jurnal Ilmu Kesejahteraan Sosial

This study focuses on the implementation of the Non-Cash Food Assistance (BPNT) policy in poverty alleviation efforts in Kembangan District, West Jakarta, during the COVID-19 pandemic. While the BPNT program managed by the Ministry of Social Affairs of the Republic of Indonesia adheres to the distribution procedures, several challenges have emerged, including delays in disbursing aid funds, invalid beneficiary data, issues with E-waroeng (food stalls), account registration, delayed distribution, and occasional inadequacy of food supplies. However, supportive factors such as effective coordination, improved data management, education, active participation from local authorities, and the commitment of E-waroeng owners have contributed to …

Implementasi Tahapan Pengembangan Masyarakat Dalam Program Perhutanan Sosial, Ahmad Nur Faizal, Moch. Ilham Noer Sunan

Jurnal Ilmu Kesejahteraan Sosial

The community's dependence on the forest makes the community's position vulnerable when access to the forest is restricted. The restrictions on community access to forests impact on emerging social problems such as poverty, conflict, and illegal logging. Responding to this problem, the government rolled out a social forestry program to improve people's lives. This research uses a qualitative approach with data collection techniques through observation, semi-structured interviews, and documentation to study in depth how the community development stages are implemented in the social forestry program in Burno Village. The results showed that there were community development efforts from CDK Lumajang …

Desa Wisata Atau Wisata Desa:Menelaah Fase Kesepian Masyarakat Pasca Pandemi Covid -19, Maureen Wanda Sabrina, Kania Saraswati Harisoesyanti

Jurnal Ilmu Kesejahteraan Sosial

The Tourism Village Policy launched by the government has developed into an ambitious initiative that can boost the community's economy. However, behind this dream, there is a complex discussion about how ready the village community is to undertake this transformation. This article discusses the stages of the community undergoing the tourism village program against the background of Taraju Village having limited access, the existence of newly formed supporting community self-help groups, and even the community's initial rejection of the development of a tourism village. Meanwhile, this tourist village has achieved achievements on a provincial and national scale. The research used …

Peran Program Pengembangan Petani Sebagai Implementasi Csr Pt. Smgp Terhadap Resistensi Masyarakat, Ahmad Taufik, Indra Lestari

Jurnal Ilmu Kesejahteraan Sosial

The presence of mining projects or power plants that utilize or exploit natural resources has the potential for environmental, social, and economic problems for the community. There are many cases of rejection from communities around the project area, which can even lead to conflict and anarchic actions that cause losses for several parties. Meanwhile, there are demands for energy sustainability amidst the current crisis in the availability of fossil energy. Therefore, the government provides support through several policies, one of which is encouraging the implementation of Corporate Social Responsibility so that core project activities can take place with attention to …

Evaluating The Efficacy Of Medication-Assisted Treatment For First Episode Psychosis: A Scoping Review, Chanel Thomas Msn, Aprn, Fnp-Bc, Rn-Bc, Alexandra Wittenberg Bsn, Rn-Bc, Anttrenika Anderson Bsn, Rn, Tracy Mcclinton Dnp, Aprn, Agacnp-Bc, Ebp-C

Doctor of Nursing Practice Projects

Purpose/Background

The Substance Abuse and Mental Health Services Administration (SAMHSA) recommends that individuals with substance use disorder (SUD) receive medicated-assisted treatment (MAT), as a complete approach to substance use treatment (SAMHSA, 2019). However, treatment measures using combination treatment for SUD in individuals experiencing first episode psychosis (FEP) are seldom used. This scoping review assesses the efficacy of MAT in conjunction with antipsychotics compared to the use of antipsychotic monotherapy for FEP individuals on hospital readmission rates.

Methods

The authors conducted a literature review utilizing PubMed, EBSCO, Elsevier, Google Scholar, PsychINFO, and Medline from August 2020 to November 2022. Key phrases …

Sexual Health And Relationship Abuse Interventions In Pediatric Primary Care: A Systematic Review, Susheel Kant Khetarpal, Sarah Tiffany-Appleton, Erin E Mickievicz, Romina L Barral, Kimberly A Randell, Jeff R Temple, Elizabeth Miller, Maya I Ragavan

Faculty, Staff and Student Publications

PURPOSE: Supporting adolescents in developing healthy relationships and promoting sexual and reproductive health (SRH) is an important responsibility of pediatric primary care providers. Less is known about evidence-based interventions in pediatric settings focused on healthy relationships and SRH.

METHODS: We conducted a systematic review to describe SRH and healthy relationship/adolescent relationship abuse (ARA) interventions for pediatric primary care over the past 20 years. Eligible articles were original research on an SRH-focused or ARA-focused intervention, conducted in-person within pediatric primary care or school-based health centers specifically for middle or high school-aged adolescents. Data abstracted from included articles included intervention description, content, …