Substance Abuse and Addiction Commons^™

Adolescent And Adult Nicotine Exposure On The Acquisition Of Methamphetamine Self-Administration And The Reinstatement Of Extinguished Methamphetamine-Seeking In Male Rats, Joseph Allan Pipkin

Theses Digitization Project

This study sought to determine the individual and combined contribution of adolescent and adult nicotine exposure on METH self-administration and METH-seeking behavior in male rats. Nicotine is a commonly abused substance among adolescents and is believed to be a "gateway" to other drugs of abuse. In support of the gateway hypothesis, cigarette smoking during adolescence is related to increased methamphetamine (METH) use in adulthood.

Preweanling Exposure To Selective Catecholamine Transporter Inhibitors Differentially Effects Morphine-Induced Antinociception In Adulthood, Joseph Marco Valentine

Theses Digitization Project

The purpose of this project is to determine how early methylphenidate exposure alters opioid receptor functioning in adulthood. To this end, we will administer selective monoamine transporter inhibitors for dopamine and norepinephrine (GBR-12904 and atomoxetine) during preweanling period and assess opioid function in adult rats by testing morphine-induced antinociception using the hot-plate and tail-flick tasks. In order to assess the effects of methylphenidate use on brain functions during development, investigations have been conducted in rats using ages roughly analogous to early and late childhood.

Personality And Substance Abuse, Juliana Gonzalez

Masters Theses

The Big Five have shown to be distinct personality traits that do not overlap and have universal applicability, so this study examined whether there are specific personality trait differences in users of Marijuana, Pain Medication, Sedative/Hypnotics, and Stimulants.

Study was placed in the 50 most visited Craigslist pages in the United States. Anonymous web users (N = 547) were recruited through Craigslist. High Neuroticism was associated with Marijuana and Stimulant use. Low Conscientiousness was associated with Marijuana and Stimulant use. High Extraversion was associated with Pain Medication use only. Implications, limitations, and suggestions for future research were discussed.

A Brief Motivational Intervention For Heavy Alcohol Use In Dental Practice Settings: Rationale And Development, James A. Neff, Scott T. Walters, Abby L. Braitman, Michelle L. Kelley, Michele L. Darby, Margaret F. Lemaster

Psychology Faculty Publications

Although brief alcohol interventions have proven effective in a variety of health care settings, the present article describes the development of the first brief intervention for heavy drinkers in dental practice. Elements of motivational interviewing and personalized normative feedback were incorporated in a 3- to 5-minute intervention delivered by dental hygienists. The intervention is guided by a one-page feedback report providing personalized normative feedback regarding the patient's current oral health practices, their drinking in comparison to others, and oral cancer risk associated with current smoking and drinking. Future publications will present data regarding intervention effectiveness from an ongoing randomized trial.

Daily Use Of Protective Behavioral Strategies And Alcohol-Related Outcomes Among College Students, Matthew R. Pearson, Gabrielle M. D'Lima, Michelle L. Kelley

Psychology Faculty Publications

The purpose of the present study was to examine associations between use of protective behavioral strategies (PBS) and alcohol-related outcomes (alcohol consumption, negative alcohol consequences, and positive alcohol consequences) using a daily diary approach. This approach is less affected by retrospective memory biases than typical self-reports of alcohol-related variables and allows the examination of both between-subjects and within-person effects. Using hierarchical linear modeling of data from 40 subjects who completed daily dairies for up to 15 days, we found significant within-person variation in PBS use over time, and each type of PBS had unique relationships with alcohol-related outcomes. For example, …

Predictive Effects Of Good Self-Control And Poor Regulation On Alcohol-Related Outcomes: Do Protective Behavioral Strategies Mediate?, Matthew R. Pearson, Benjamin A. Kite, James M. Henson

Psychology Faculty Publications

In the present study, we examined whether use of protective behavioral strategies mediated the relationship between self-control constructs and alcohol-related outcomes. According to the two-mode model of self-control, good self-control (planfulness; measured with Future Time Perspective, Problem Solving, and Self-Reinforcement) and poor regulation (impulsivity; measured with Present Time Perspective, Poor Delay of Gratification, Distractibility) are theorized to be relatively independent constructs rather than opposite ends of a single continuum. The analytic sample consisted of 278 college student drinkers (68% women) who responded to a battery of surveys at a single time point. Using a structural equation model based on the …

Alcohol Use And Trauma Exposure Among Male And Female Veterans Before, During, And After Military Service, Michelle L. Kelley, Jennifer Runnals, Matthew R. Pearson, Marinell Miller, John A. Fairbank, Va Mid-Atlantic Mirecc Women Veterans Workgroup

Psychology Faculty Publications

Background: The present study examined lifespan and combat-related trauma exposure as predictors of alcohol use among male and female veterans. Posttraumatic stress and depressive symptoms were examined as mediators of the effects of trauma exposure on alcohol use.

Methods: Data were examined from 1825 (1450 male, 375 female) veterans and active duty service members who took part in a multi-site research study conducted through the Department of Veterans Affairs Mid-Atlantic Mental Illness Research, Education and Clinical Center (VISN 6 MIRECC).

Results: For both men and women, depressive symptoms significantly mediated the effects of non-combat trauma exposure experienced before, during and …

The Assessment Of Protective Behavioral Strategies: Comparing The Absolute Frequency And Contingent Frequency Response Scales, Benjamin A. Kite, Matthew R. Pearson, James M. Henson

Psychology Faculty Publications

The purpose of the present studies was to examine the effects of response scale on the observed relationships between protective behavioral strategies (PBS) measures and alcohol-related outcomes. We reasoned that an "absolute frequency" scale (stem: "how many times..."; response scale: 0 times to 11 + times) conflates the frequency of using PBS with the frequency of consuming alcohol; thus, we hypothesized that the use of an absolute frequency response scale would result in positive relationships between types of PBS and alcohol-related outcomes. Alternatively, a "contingent frequency" scale (stem: "When drinking ... how often ..."; response scale: never to always …

Effects Of Restraint Stress And Allopregnanolone Inhibition On Amphetamine Locomotor Sensitivity, Kelly Abuali, Laurel M. Pritchard

McNair Poster Presentations

The chronic, recurring nature of addiction remains a worldwide problem. Even after apparently successful clinical treatment and long term abstinence, individuals may still relapse many months or years later. Although many individual differences exist among substance abusers, relapse tends to occur during periods of high stress (Sinha et al., 2006). Behavioral training and therapy can help cope during these high stress times, but pharmacological interventions have not been shown to be effective (Ross & Peselow, 2009). Although some therapeutic options decrease relapse rates, more effective treatments for relapse need further consideration.

The effect of stress on use of and relapse …

An Analysis Of Treatment Retention And Attrition In An Australian Therapeutic Community For Substance Abuse Treatment, Mark Robert Porter

Theses: Doctorates and Masters

Research undertaken in the last three decades has consistently reported that the length of time spent in inpatient and outpatient alcohol and other drug (AOD) treatment programs predicts treatment success (De Leon, Melnick, Kressel, & Jainchill, 1994; Hubbard, Craddock, & Anderson, 2003; Simpson, Joe, Fletcher, Hubbard, & Anglin, 1999). However, treatment attrition rates are high and present a major problem for improving treatment outcomes. Various factors that have been reportedly associated with increased AOD treatment attrition rates include being female, younger clients, clients using methamphetamines, and clients with elevated psychopathology scores. The aim of this thesis is to improve understanding …

Unplanned Drinking And Alcohol-Related Problems: A Preliminary Test Of The Model Of Unplanned Drinking Behavior, Matthew R. Pearson, James M. Henson

Psychology Faculty Publications

Much research links impulsivity with alcohol use and problems. In 2 studies, unplanned (or impulsive) drinking is assessed directly to determine whether it has direct effects on alcohol use and alcohol-related problems. In Study 1, we examined whether unplanned drinking serves as a proximal mediator of the effects of impulsivity-like traits on alcohol-related outcomes. With a sample of 211 college student drinkers, we found that the Unplanned Drinking Scale was significantly related to alcohol use, and perhaps more important, had a direct effect on alcohol-related problems even after controlling for frequency and quantity of alcohol use. Furthermore, unplanned drinking partially …

The Initial Development Of Child-Focused Interventions In The Treatment Of Maternal Substance Abuse And Child Neglect, Kendra Tracy

UNLV Theses, Dissertations, Professional Papers, and Capstones

This single case study focuses on the development and evaluation of child focused interventions for the treatment of child neglect and concurrent maternal substance abuse that were incorporated into Family Behavior Therapy (FBT). The participants were a mother referred by the Department of Family Services and her child. The child participated in three child focused interventions that were developed to decrease child behavior problems, increase support and communication, and prevent future neglect by strengthening the mother & child relationship. Although not a focus in this study, the mother participated in traditional FBT adult focused intervention components. The chief aim of …

An Evaluation Of Social Capital's Effect On Depression Among Adolescents, Ezechukwu Awgu

Dissertations

Mental illness has been described as a “global burden of disease,” and depression accounts for a large part of the burden (Aslund, Starrin, Nilsson, 2010). In 2009, 35.7 percent of the adolescent population in the United States who reported past-year symptoms of a major depressive episode, for example, feelings of sadness, discouragement, loss of feelings of self-worth, and loss of interest in social activities, also used illicit drugs including marijuana, inhalants, hallucinogens, cocaine, heroin, and prescription-type psychotherapeutics for non-medical purposes (SAMHSA, 2009, APA, 1994). Additionally, substance abuse due to alcoholism was among the major causes of death for adolescents aged …

Racism And Illicit Drug Use Among African American Women: The Protective Effects Of Ethnic Identity, Affirmation, And Behavior, Danelle Stevens-Watkins, Brea Perry, Kathi L. Harp, Carrie B. Oser

Sociology Faculty Publications

Though recent evidence indicates that rates of illicit drug use among African American women are now higher than the national average, little is known about the etiology of substance use in this population. In addition, the effects of racism and other cultural factors are understudied and may be unique amongst African American women. This cross-sectional study explores risk and protective factors for drug use among 204 African American women. More specifically, associations between racism experiences and drug use are investigated in the context of potential moderating influences (i.e., psychosocial resources, social safety net variables, and cultural identity and practices). Findings …

Multiple Peer Group Self-Identification And Adolescent Tobacco Use, C. Anderson Johnson, Juliana L. Fuqua, Peggy E. Gallaher, Jennifer B. Unger, Dennis R. Trinidad, Steve Sussman, Enrique Ortega

CGU Faculty Publications and Research

Associations between peer group self-identification and smoking were examined among 2,698 ethnically diverse middle school students in Los Angeles who self-identified with groups such as Rockers, Skaters, and Gamers. The sample was 47.1% male, 54.7% Latino, 25.4% Asian, 10.8% White, 9.1% Other ethnicity, and 59.3% children of immigrant parents. Multiple group self identification was common: 84% identified with two or more groups and 65% identified with three or more groups. Logistic regression analyses indicated that as students endorsed more high risk groups, the greater their risk of tobacco use. A classification tree analysis identified risk groups based on interactions among …

Testing The Indirect Effect Of Trait Mindfulness On Adolescent Cigarette Smoking Through Negative Affect And Perceived Stress Mediators, C. Anderson Johnson, David S. Black, Joel Milam, Steve Sussman

CGU Faculty Publications and Research

Mindfulness refers to an enhanced attention to and awareness of present moment experience. This study examined how trait mindfulness, as measured with six items from Mindfulness Attention Awareness Scale, might influence adolescent cigarette smoking frequency through its impact on depressive affect, anger affect and perceived stress mediators. Self-reported data from Chinese adolescents (N = 5287, mean age = 16.2 years, SD = 0.7; 48.8% females) were collected within 24 schools. The product of coefficients test was used to determine significant mediation paths. Results from baseline cross-sectional data indicated that trait mindfulness had a significant indirect effect on past 30-day …

Differential Effects Of Acute Amphetamine And Phencyclidine Treatment And Withdrawal From Repeated Amphetamine Or Phencyclidine Treatment On Social Interaction And Social Memory In Rats, Ming Li, Wei He, Rebecca Munro

Department of Psychology: Faculty Publications

Although animal models based on amphetamine (AMPH) or phencyclidine (PCP) treatment have been used extensively to study the neurobiological and behavioral characteristics of schizophrenia, there are conflicting reports regarding their validity in modeling the negative symptoms and cognitive deficits of schizophrenia. The present study examined how acute AMPH or PCP treatment (Experiment 1) and withdrawal from repeated AMPH treatment (Experiment 2) or PCP treatment (Experiment 3) affects social behavior and social recognition memory in male Sprague-Dawley rats. Each subject was tested on two consecutive days. On the first day, the rats were tested four times (5 min/each) at 10-min intervals …

The Effects Of Adolescent Heavy Drinking On The Timing And Stability Of Cohabitation And Marriage, Lela Rankin Williams, Laura Wray-Lake, Eric Loken, Jennifer L. Maggs

CGU Faculty Publications and Research

Based on prospective British Cohort Study data, adolescent alcohol use predicted the timing and stability of committed partnerships between 16 and 34 years (n = 3278; 59% female). Propensity score methods balanced age 16 heavy drinkers (32.4%) and nonheavy drinkers on a range of relevant risk factors assessed in infancy and childhood. Adolescent heavy drinking predicted having ever cohabited, earlier transitions into cohabiting and marital relationships, more breakups, and an increased likelihood of divorce. Gender and social class moderated these relationships; heavy-drinking working-class males were especially likely to cohabit and to experience early entry into cohabitation and marriage. Implications …

The Phenomenology Of Court-Ordered Treatment: From The Perspective Of Methamphetamine Dependent Adults, Justin Steffener

Antioch University Dissertations & Theses

This phenomenological study was designed to explore with a sample of methamphetamine dependent adults their perceptions of the process involved in their experiences of court-ordered treatment. The motivation for this study derives from the researcher's wish to unearth ways to better understand and support the needs of adults suffering from addiction. A significant amount of research has already been conducted in regards to the treatment of methamphetamine addiction from the standpoint of quantitative measurements of treatment outcomes, but limited information is presently available from the perspective of the suffers. The stringent selection of the sample was composed of six individuals …

Attentional Bias And Alcohol Abuse, Jessica Jane Weafer

Theses and Dissertations--Psychology

Selective attention towards alcohol-related cues (i.e., “attentional bias”) is thought to reflect increased incentive motivational value of alcohol and alcohol cues acquired through a history of heavy alcohol use, and as such attentional bias is considered to be a clinically relevant factor contributing to alcohol use disorders. This dissertation consists of two studies that investigated specific mechanisms through which attentional bias might serve to promote alcohol abuse. Study 1 compared magnitude of attentional bias in heavy (n = 20) and light (n = 20) drinkers following placebo and two doses of alcohol (0.45 g/kg and 0.65 g/kg). Heavy drinkers displayed …

Drinking Buddies And Their Prospective Influence On Alcohol Outcomes: Alcohol Expectancies As A Mediator, Cathy Lau-Barraco, Abbly L. Braitman, Kenneth E. Leonard, Miguel Padilla

Psychology Faculty Publications

The process by which peers or the social network influence individual alcohol use, particularly among adults, remains a necessary area of research. The purpose of the present study was to examine the longitudinal influence of "drinking buddies" on alcohol outcomes (i.e., alcohol use, heavy drinking, and alcohol-related problems) as mediated by alcohol expectancies of social facilitation. Participants were 1347 (men = 660, women = 687) newly married individuals recruited from the community. They were assessed at the time of marriage and through the fourth wedding anniversary. Longitudinal mediation across time was evaluated using latent growth modeling. Overall, the prospective association …

The Consequences Of Early Onset Alcohol Experimentation: Adaptive Exploration On Downward Trajectory, Marjorie Grefer

Kaleidoscope

No abstract provided.

The Structure Of Client Language And Drinking Outcomes In Project Match, Tim Martin, Paulette J. Christopher, Jon M. Houck, Theresa B. Moyers

Faculty Articles

Client language during Motivational Interviewing interventions is an important predictor of drinking outcomes, but there are inconsistencies in the literature regarding what aspects of client language are most predictive. We characterized the structure of client language by factor analyzing frequency counts of several categories of client speech. The results provide limited support for a model proposed by Miller et al. (2006) and Amrhein et al. (2003) but with some important differences. While Amrhein et al. (2003) found that only increasing strength in client commitment language predicted behavior change, the current study revealed that client language preparatory to commitment predicted drinking …

Implementation Of The 2009 Cacrep Standards Addiction Competencies, Tiffany K. Lee

Dissertations

Addiction issues have been and continue to be significant problems affecting the United States. Over the past few decades, substantial scholarly attention has been paid to the lack of addictions training in the counseling profession. The purposes of this mixed-method study were to examine the current status of addiction training among institutions that offer counselor education programs accredited by the Council for Accreditation of Counseling and Related Educational Programs (CACREP) and determine how institutions plan to integrate the addiction-related competencies outlined in the 2009 CACREP standards.

The quantitative data were obtained from a 15-item online survey completed by 74 CACREP …

Effectiveness Of A Motivational Enhancement Group Treatment In A Community Treatment Program With A Substance Abusing Population, Matthew S. Willerick

Dissertations

Motivational interviewing (MI) is a directive, client-centered intervention to elicit behavior change by assisting clients in the exploration and resolution of ambivalence toward change. MI-inspired approaches have been used in an attempt to facilitate change in a wide variety of domains including alcohol and drug abuse, safe water handling practices, dual diagnoses, gambling, spousal abuse, health related areas, mood and anxiety disorders, and parental engagement. MI seeks to resolve ambivalence in the direction of change by increasing the client's self-efficacy. This is accomplished by combining clientcentered (e.g., reflective listening) and directive strategies (e.g., attending selectively to change statements). The origins …

Polyamine Modulation In Alcoholism: Examination Using A Novel Screening Procedure Designed To Predict Anti-Relapse And Neuroprotective Efficacy, J. Ben Lewis

University of Kentucky Doctoral Dissertations

Alcohol dependence is a major public health concern. Despite the FDA’s approval of multiple anti-relapse drugs, relapse rates remain unacceptably high. Furthermore, cognitive deficits among chronic drinkers are evident and are suggested to contribute to relapse risk. Current evidence suggests that several critical features of alcoholism and alcohol-associated neurodegeneration are mechanistically linked to glutamatergic actions; specifically, they appear positively affected by glutamatergic inhibition, particularly inhibition via polyamine modulation of a subpopulation of n-methyl-d-aspartate receptors. The current project was designed to evaluate the performance of two putative polyamine modulators (JR-220 and CP-101,606) in a variety of screens designed …

2011-2012 Unlv Mcnair Journal, Cyndy Anang, Sajar Camara, Pamela Cornejo, Carla Antonieta Farcello, Ilse Anahi Garcia, Natiera Magnuson, William L. Mccurdy, Lorena Munoz, Maxym V. Myroshnychenko, Ricardo Rios, Theodore Waldeck, Barbara Wallen, Ana Zuniga, Brenda M. Aguilar, Tiffany Alexandra Alvarez, Daniel N. Erosa, Paige C. Espinosa, Carla Antonieta Farcello, Julienne Jochel Paraiso, Nathaniel Derek Phillipps, Carmen Vallin, Jacent N. Wamala, Ernesto Zamora-Ramos

McNair Journal

Journal articles based on research conducted by undergraduate students in the McNair Scholars Program

Table of Contents

Biography of Dr. Ronald E. McNair

Statements:

Dr. Neal J. Smatresk, UNLV President

Dr. Juanita P. Fain, Vice President of Student Affairs

Dr. William W. Sullivan, Associate Vice President for Retention and Outreach

Mr. Keith Rogers, Deputy Executive Director of the Center for Academic Enrichment and Outreach

McNair Scholars Institute Staff

Therapist-Initiated Addiction Assessment Procedures Of Marriage And Family Therapists In The Southwest United States, Emire Olmeztoprak

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to examine the addiction assessment procedures of marriage and family therapists. Addiction prevalence rates are growing therefore it is likely that marriage and family therapists will have clients affected by addiction. Undetected addictions can impede treatment and/or prevent the therapist from making appropriate treatment related decisions. Marriage and family therapists in Nevada, Arizona, and New Mexico were invited to complete a web-based survey containing a series of questions about their assessment procedures for addiction as well as a series of demographics questions. The data from the completed surveys was collected and analyzed. The data …

Impulsivity, Impulsive And Reflective Processes And The Development Of Alcohol Use And Misuse In Adolescents And Young Adults, Reinout W. Wiers, Susan L. Ames, Wilhelm Hofmann, Marvin Krank, Alan W. Stacy

CGU Faculty Publications and Research

This paper contrasts dual-process and personality approaches in the prediction of addictive behaviors and related risk behaviors. In dual-process models, behavior is described as the joint outcome of qualitatively different “impulsive” (or associative) and “reflective” processes. There are important individual differences regarding both types of processes, and the relative strength of both in a specific situation is influenced by prior behavior and state variables (e.g., fatigue, alcohol use). From this perspective, a specific behavior (e.g., alcohol misuse) can be predicted by the combined indices of the behavior-related impulsive processes (e.g., associations with alcohol), and reflective processes, including the ability to …

Experimental Analysis Of Gambling Using A Concurrent-Schedules Procedure, Andrew Ellis Brandt

Dissertations

Gambling has been experimentally investigated using various types of gambling simulations designed to mimic the contingencies found in real-world games of chance. Findings from past risky choice research suggest that certain procedures used in existing gambling simulations may systematically increase levels of gambling. Two of these characteristics, the use of a participant stake and the type of options available during gambling, were tested in four experiments in which participants had the opportunity to gamble using tokens exchangeable for entries into a $50 lottery. Experiments 1 and 2 tested persistence on a gamble option when either a single-option or a concurrent …