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Psychiatric and Mental Health Commons

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2016

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Articles 31 - 60 of 119

Full-Text Articles in Psychiatric and Mental Health

Antenatal Glucocorticoid Treatment Is Associated With Diurnal Cortisol Regulation In Term-Born Children, M. N. Edelmann, Curt A. Sandman, Laura M. Glynn, D. A. Wing, Elyssia Poggi Davis Jun 2016

Antenatal Glucocorticoid Treatment Is Associated With Diurnal Cortisol Regulation In Term-Born Children, M. N. Edelmann, Curt A. Sandman, Laura M. Glynn, D. A. Wing, Elyssia Poggi Davis

Psychology Faculty Articles and Research

Due to the rapid developmental changes that occur during the fetal period, prenatal influences can affect the developing central nervous system with lifelong consequences for physical and mental health. Glucocorticoids are one of the proposed mechanisms by which fetal programing occurs. Glucocorticoids pass through the blood-brain barrier and target receptors throughout the central nervous system. Unlike endogenous glucocorticoids, synthetic glucocorticoids readily pass through the placental barrier to reach the developing fetus. The synthetic glucocorticoid, betamethasone, is routinely given prenatally to mothers at risk for preterm delivery. Over 25% of the fetuses exposed to betamethasone will be born at term. Few …


Transgender Patients' Experiences Of Discrimination At Mental Health Clinics, Corrine Ann Stocking Jun 2016

Transgender Patients' Experiences Of Discrimination At Mental Health Clinics, Corrine Ann Stocking

Dissertations and Theses

The transgender population is makes up about 0.3% of the U.S. population (Gates 2011). The term transgender is both an identity and an umbrella term used to describe people who do not adhere to traditional gender norms (Institute of Medicine 2011). Transgender people experience many barriers to services, negative health outcomes, and discrimination (Fredrikson-Goldsen et al. 2013; Institute of Medicine 2011; Eliason et al. 2009; Hendricks & Testa 2012). Mental health clinics are an important site for understanding transgender peoples' experiences due to being a gatekeeper for other medical services and their role in helping transpeople with issues surrounding coming …


Facing Our Demons: Psychiatric Perspectives On Exorcism Rituals, Joel R. Sanford Jun 2016

Facing Our Demons: Psychiatric Perspectives On Exorcism Rituals, Joel R. Sanford

The Hilltop Review

Belief in possession by malevolent spirits exists in many cultures and religions throughout the world, and such beliefs often serve as explanations for a variety of psychological and emotional afflictions. Traditional remedies in these cases often involve exorcism rituals, which are believed to expel spirits from a person's mind and/or body. Some of the cases commonly attributed to involuntary spirit possession are diagnosed within the psychiatric community as schizophrenia or some sort of dissociative disorder and treated with psychotherapy and/or medicine. For some in the psychiatric community, exorcisms and their use by patients are viewed as problematic due to their …


Unconfessing Transgender: Dysphoric Youths And The Medicalization Of Madness In John Gower’S “Tale Of Iphis And Ianthe”, M W. Bychowski Jun 2016

Unconfessing Transgender: Dysphoric Youths And The Medicalization Of Madness In John Gower’S “Tale Of Iphis And Ianthe”, M W. Bychowski

Accessus

On the brink of the twenty-first century, Judith Butler argues in “Undiagnosing Gender” that the Diagnostic and Statistical Manual of Mental Disorders (DSM) defines the psychiatric condition of “Gender Identity Disorder” (or “Gender Dysphoria”) in ways that control biological diversity and construct “transgender” as a marginalized identity. By turning the study of gender away from vulnerable individuals and towards the broader systems of power, Butler works to liberate bodies from the medical mechanisms managing difference and precluding potentially disruptive innovations in forms of life and embodiment by creating categories of gender and disability.

Turning to the brink of the 15 …


La Folie Comme Aliénation Et Dissidence Chez Mongo Beti Et V.Y. Mudimbe, Florian Alix Jun 2016

La Folie Comme Aliénation Et Dissidence Chez Mongo Beti Et V.Y. Mudimbe, Florian Alix

Présence Francophone: Revue internationale de langue et de littérature

In Le pauvre Christ de Bomba and Entre les eaux, the narrator’s evolution seems a kind of madness, as Ambroise Kom defined it: a process of social exclusion based on alienation because of norms told by dominant discourses. Individuals can’t find their right place in front of “languages in madness” which rule the colonial thought and hide part of reality. Therefore novel becomes a space where individual madness appears as a dissidence against dominant discourses.


Psychological Abuse, Mental Health, And Acceptance Of Dating Violence Among Adolescents, Jeff R. Temple, Hye Jeong Choi, Joanna Elmquist, Michael L. Hecht, Michelle Miller-Day, Gregory L. Stuart, Meagan Brem, Caitlin Wolford-Clevenger May 2016

Psychological Abuse, Mental Health, And Acceptance Of Dating Violence Among Adolescents, Jeff R. Temple, Hye Jeong Choi, Joanna Elmquist, Michael L. Hecht, Michelle Miller-Day, Gregory L. Stuart, Meagan Brem, Caitlin Wolford-Clevenger

Communication Faculty Articles and Research

Purpose

Existing literature indicates that acceptance of dating violence is a significant and robust risk factor for psychological dating abuse perpetration. Past work also indicates a significant relationship between psychological dating abuse perpetration and poor mental health. However, no known research has examined the relationship between acceptance of dating violence, perpetration of dating abuse, and mental health. In addition to exploring this complex relationship, the present study examines whether psychological abuse perpetration mediates the relationship between acceptance of dating violence and mental health (i.e., internalizing symptoms of depression, anxiety, and hostility).

Methods

Three waves of longitudinal data were obtained from …


Improving Suicide Risk Management In Military Primary Care, John A. Hoyos May 2016

Improving Suicide Risk Management In Military Primary Care, John A. Hoyos

Doctor of Nursing Practice Final Manuscripts

Background: In the military, completed suicides and attempt rates have risen across the services since 2001 by 82% per 100,000 in spite of various intervention programs. The literature suggests that absent and inadequate suicide assessments may be part of the problem. Primary care providers are often not prepared for risk assessment and management of suicidal patients.

Aim/Purpose of Project: The project sought to improve the consistency of providers in conducting adequate risk assessments and providing crisis hotline information to patients who were cleared to return home after an encounter, as required by NPSG 15.01.01.

Project Plan Process: This evidenced-based project …


Adolescent Grief: The Nurse's Role In Promoting Healthy Coping Mechanisms And Preventing Future Hospitalizations, Erica C. Reighard May 2016

Adolescent Grief: The Nurse's Role In Promoting Healthy Coping Mechanisms And Preventing Future Hospitalizations, Erica C. Reighard

Senior Honors Projects, 2010-2019

Age and developmental stage directly influence the grieving individual's ability to understand and process death. Adolescents are especially vulnerable to developing negative coping skills such as substance abuse, self-destructive behaviors, and eating disorders. After a loss occurs, nurses can use their role as a caregiver who is neither a parent nor a peer to provide adolescents with an opportunity to express their grief. Nurses can educate grieving adolescents on the differences between positive and negative coping skills and can therefore reduce the number of future hospitalizations related to ineffective coping mechanisms.


Rural Nebraska Women's Explanatory Models Of Postpartum Depressive Symptomatology, Elizabeth Mollard May 2016

Rural Nebraska Women's Explanatory Models Of Postpartum Depressive Symptomatology, Elizabeth Mollard

Theses & Dissertations

The purpose of this study was to construct the explanatory models of postpartum depressive symptomatology (PPDS) from the perspective of rural Nebraska women and to compare these models with the medical model of PPDS. A sample of 20 rural Nebraska women were interviewed in a one-on-one qualitative descriptive telephone interview using questions based on Kleinman’s (1980) explanatory model of illness. This study used feminist pragmatism as a guiding philosophical paradigm. Qualitative data were analyzed using content analysis, and results were compared and contrasted with the medical model of PPDS, which included the onset, symptoms, and duration listed in the DSM-5 …


A Mixed Methods Analysis Of The Relationship Between Attachment, Post-Traumatic Stress, And Post-Traumatic Growth Among United States Service Members, Chauncy T. Brinton May 2016

A Mixed Methods Analysis Of The Relationship Between Attachment, Post-Traumatic Stress, And Post-Traumatic Growth Among United States Service Members, Chauncy T. Brinton

Dissertations, 2014-2019

The impact of secure military relationships on US service members’ response to trauma during military service was examined in this mixed methods study. Veterans with and without combat exposure evidence a high rate of post-traumatic stress disorder (PTSD) and the military has tried to institute resilience-based programs in anticipation of the psychological challenges experienced by soldiers. At the same time, research has shown that some service members report positive outcomes associated with military service including the phenomena of post-traumatic growth (PTG). The constructs from attachment theory (safe haven and exploration) have begun to be the focus of research with service …


Effect Of A 72 Hour Stroke Care Bundle On Early Outcomes After Acute Stroke: A Non Randomised Controlled Study, Martha Sajatovic, Anthony J. Furlan May 2016

Effect Of A 72 Hour Stroke Care Bundle On Early Outcomes After Acute Stroke: A Non Randomised Controlled Study, Martha Sajatovic, Anthony J. Furlan

Faculty Scholarship

Background Integrated care pathways (ICP) in stroke management are increasingly being implemented to improve outcomes of acute stroke patients. We evaluated the effect of implementing a 72 hour stroke care bundle on early outcomes among patients admitted within seven days post stroke to the national referral hospital in Uganda. Methods In a one year non-randomised controlled study, 127 stroke patients who had ‘usual care’ (control group) were compared to 127 stroke patients who received selected elements from an ICP (intervention group). Patients were consecutively enrolled (controls first, intervention group second) into each group over 5 month periods and followed to …


Comparative Organizational Assessments And Partenship Potential For Sekou Pou Nanm-Yo And Asirans Community Counseling Center, Lauren M. Mawe May 2016

Comparative Organizational Assessments And Partenship Potential For Sekou Pou Nanm-Yo And Asirans Community Counseling Center, Lauren M. Mawe

Sustainability and Social Justice

This paper assesses the organizational capacity of two small Non-Governmental Organizations (NGOs) in Port-Au-Prince Haiti. Each NGO has a staff of under 15 members. At the time of the assessment, they were both in early stages of their development, with one in its first year of operations, and the other in its fifth year. Both embody grassroots, community organizations because of their connections to the communities in which they work, their willingness to travel to those communities, and their predominantly Haitian staff. The fieldwork included interviews, focus groups, and three months of participant observation and work with these organizations. In …


Facilitating Effective Communication Between First Responders And Older Adults During Fall Incidents: An Educational Intervention, Krystin M. Beeman, Erica L. Berger, Isabel A. Cabezas, Nicole M. Mathews May 2016

Facilitating Effective Communication Between First Responders And Older Adults During Fall Incidents: An Educational Intervention, Krystin M. Beeman, Erica L. Berger, Isabel A. Cabezas, Nicole M. Mathews

Dissertations, Masters Theses, Capstones, and Culminating Projects

PURPOSE. The purpose of this project was to provide first responders with communication strategies for older adults that may help when responding to fall- related calls. General information was also provided to First Responders on working with older adults with a focus on the aging process, fall risk factors, and communications strategies.

METHODS. A series of educational sessions to first responders at a local fire district were developed and presented by occupational therapy students. Materials were developed by presenters from evidence-based resources and tailored to the target population. Each presentation focused on statistics about older adults, the aging process, fall …


Instilling Hope: Showing Individuals With New Disabilities Between The Ages Of 18 And 24 That Suicide Is Not The Answer, Christine Ann Whiting May 2016

Instilling Hope: Showing Individuals With New Disabilities Between The Ages Of 18 And 24 That Suicide Is Not The Answer, Christine Ann Whiting

Graduate Theses and Dissertations

The purpose of this dissertation is to explore what can be done to mitigate the onset of a disability for young adults aged 18-24 in order to prevent suicidal thoughts or actions. Research suggests that many factors play into suicidal ideation for this young population, including lost hope, lack of coping mechanisms, lack of financial security and bullying. The goal of this research is to determine what rehabilitation professionals can do differently that will hopefully eradicate suicide for this group.


Staff Interactions And Affect In Persons With Dementia: An Observational Study Of A Memory Care Unit, Keirstin V. Meyer May 2016

Staff Interactions And Affect In Persons With Dementia: An Observational Study Of A Memory Care Unit, Keirstin V. Meyer

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

It is estimated that the number of people in the United States living with dementia in 2015 will nearly triple by the year 2050. With no cure for dementia, we are faced with providing care in a way that maximizes well-being. The majority of prior research focused on the best ways to reduce behavioral problems and mood disorders, such as depression and anxiety. The objective of this study was to increase knowledge about the social influences on well-being in persons with dementia, particularly from staff in residential memory care units. This study found that the most common interaction type from …


Nursing Perception Of Psychogenic Nonepileptic Spells: Improving Patient Outcomes, Amanda J. Cramer Apr 2016

Nursing Perception Of Psychogenic Nonepileptic Spells: Improving Patient Outcomes, Amanda J. Cramer

Doctor of Nursing Practice Scholarly Projects

Patients with psychogenic nonepileptic spells (PNES) have generally poor outcomes and many fail to engage in evidence-based treatments (Thompson et al., 2013). Negative healthcare provider perceptions have been implicated as a barrier to patient engagement in treatment recommendations for PNES (Whitehead, Kandler, & Reuber, 2013; Worsely et al., 2011). Illness perception of these patients has been evaluated from the perspective of physicians in multiple settings but perceptions by nurses are not well studied despite the close interactions that nurses have with these patients.

This project used Pender’s health promotion model to collect information about the nursing experience with patients with …


Examination Of The Use Of Accelerated Resolution Therapy (Art) In The Treatment Of Symptoms Of Ptsd And Sleep Dysfunction In Veterans And Civilians, Marian Jevone Hardwick Apr 2016

Examination Of The Use Of Accelerated Resolution Therapy (Art) In The Treatment Of Symptoms Of Ptsd And Sleep Dysfunction In Veterans And Civilians, Marian Jevone Hardwick

USF Tampa Graduate Theses and Dissertations

Posttraumatic Stress Disorder (PTSD) is a prevalent anxiety disorder that is debilitating to both veterans and civilians following one or more traumatic events. Sleep disturbances are hallmark features of PTSD. Sleep disturbances and PTSD remain two significant PTSD-related issues that continue to plague veterans returning from active duty, thereby preventing full reintegration into society. The same problem exists for civilians. This research was conducted as a previously collected pilot study data and a secondary data analysis. The purpose of the study consisted of: 1) examining the impact of treatment with Accelerated Resolution Therapy (ART) on symptoms of PTSD and sleep …


An Intensive Aphasia Needs Assessment Tool, Dalana Marie Henson Apr 2016

An Intensive Aphasia Needs Assessment Tool, Dalana Marie Henson

Masters Theses & Specialist Projects

Persons with aphasia (PWAs) often demonstrate challenges in the areas of expressive language, comprehension, reading, and writing. Due to these deficits, PWAs have limited opportunity to express their opinions and contribute to treatment planning. This project focused on the development of a self-report needs assessment tool for PWAs that facilitates PWAs participation in treatment planning. The needs assessment tool was designed using aphasia-friendly features including pictographic/visual analog scale, key words in bold, simple wording, large font, consistent question formatting, flexible administration, and the use of a communication partner/interview. The needs assessment tool was administered to seven PWAs in the Bowling …


All Things New: A Holistic Theology Of Major Depression And Pastoral Care, T. S. Giovanetto Apr 2016

All Things New: A Holistic Theology Of Major Depression And Pastoral Care, T. S. Giovanetto

Journal of Applied Christian Leadership

Dissertation Notice:

M.A. Thesis, Trinity International University, 2015.

Full Text of the Thesis available from ProQuest Dissertations & Theses Global

This study approaches the topic of mental illness within the church, integrating biblical theology and clinical psychology to propose a model of pastoral care for the severely depressed. Examining the history of distrust between the church and the social sciences, and criticizing prominent models of pastoral care built upon the chastisement of mentally ill individuals, the thesis proposes a model of care built upon the acceptance and validation of persons facing psychological distress. In this model, ministers teach sufferers to …


The Mind Body Problem, Part Three: Ascension Of Sexual Function To Cerebral Level, Ion G. Motofei, David L. Rowland Mar 2016

The Mind Body Problem, Part Three: Ascension Of Sexual Function To Cerebral Level, Ion G. Motofei, David L. Rowland

Journal of Mind and Medical Sciences

Physiologically, the somatic nervous system intervenes in external interaction between the body and environment, while autonomic nervous system ensures the functioning of internal organs. We present in this paper a psycho-physiological perspective suggesting that mental function (somatic in nature, because coordinates environmental interaction) is closer to and more aligned with the physiologic functioning of autonomic nervous system (due to autonomy, duality, etc.). At opposite end, sexual function (autonomic in nature, erection for example being a parasympathetic vasodilatory reflex) seems to be compatible and even dependent by a somatic participation (erectile response is rather induced by environmental stimuli than internal visceral …


Student Reflections Of Psychiatric/Mental Health: Using Journals And Creative Expressions, Melinda Hermanns, Barbara K. Haas Mar 2016

Student Reflections Of Psychiatric/Mental Health: Using Journals And Creative Expressions, Melinda Hermanns, Barbara K. Haas

Nursing Faculty Publications and Presentations

Second semester undergraduate nursing students in their psychiatric/mental health clinical rotation express an array of emotions as they frequently view the setting as foreign. Two assignments, reflective journaling and a form of expression were incorporated into clinical to provide students an opportunity to reflect and convey their thoughts and feelings concerning their clinical experiences. Thematic analysis was used to analyze 10 journals and 10 art forms with a written description. Two content themes emerged: A Change in Perspective and Insight. Exemplars of the students’ perspectives are provided. As evidenced by students’ submissions, reflective journaling and creative expression can be an …


Depression And Body Mass Index, Differences By Education: Evidence From A Population-Based Study Of Adult Women In The U.S. Buffalo-Niagara Region, Ashley Wendell Kranjac, Jing Nie, Maurizio Trevisan, Jo L. Freudenheim Mar 2016

Depression And Body Mass Index, Differences By Education: Evidence From A Population-Based Study Of Adult Women In The U.S. Buffalo-Niagara Region, Ashley Wendell Kranjac, Jing Nie, Maurizio Trevisan, Jo L. Freudenheim

Sociology Faculty Articles and Research

The relationship between obesity and depression is well described. However, the evidence linking depression and body mass index (BMI) across the broad range of body size is less consistent. We examined the association between depressive symptoms and BMI in a sample of adult women in the Buffalo-Niagara region between 1997 and 2001. Using logistic regression, we investigated whether increased weight status beyond normal-weight was associated with a higher prevalence of depressive symptoms, and if educational attainment modified the association between obesity and depression. There was a trend for increased weight status to be associated with higher depressive symptoms (obese II/III, …


Multiple Anti-Epileptic Drug Use In Children With Epilepsy In Mulago Hospital, Uganda: A Cross Ectional Study, Martha Sajatovic Mar 2016

Multiple Anti-Epileptic Drug Use In Children With Epilepsy In Mulago Hospital, Uganda: A Cross Ectional Study, Martha Sajatovic

Faculty Scholarship

Background: Seizures in up to one third of children with epilepsy may not be controlled by the first anti-epileptic drug (AED). In this study, we describe multiple AED usage in children attending a referral clinic in Uganda, the factors associated with multiple AED use and seizure control in affected patients. Methods: One hundred thirty nine patients attending Mulago hospital paediatric neurology clinic with epilepsy and who had been on AEDs for ≥6months were consecutively enrolled from July to December 2013 to reach the calculated sample size. With consent, the history and physical examination were repeated and the neurophysiologic and imaging …


Using Biofeedback In Hiv+ Patients, Domenique Escobar, Mikhail Kogan, Randi Abramson Mar 2016

Using Biofeedback In Hiv+ Patients, Domenique Escobar, Mikhail Kogan, Randi Abramson

GW Research Days 2016 - 2020

Background - The prevalence of HIV in Washington, DC is estimated to be at least 3%, triple what the World Health Organization defines as an epidemic. Even at that conservative estimate, the number of people living with HIV in the District of Columbia is the highest in the nation. Individuals living with HIV face stigma, anxiety, stress and depression, among a host of other physical and mental effects. Stress has a significant impact on the immune system and a biofeedback program can be of benefit to patients undergoing any stress. Biofeedback is a technique that trains people to improve their …


Between Crazy And Fine, Annette Aguilera-Gonzalez Feb 2016

Between Crazy And Fine, Annette Aguilera-Gonzalez

SURGE

As a young Latina, I grew up hiding the fact that I met with a therapist and that I suffered from depression and anxiety. Conversations about mental well-being or taking steps to cope with anxiety were non-existent in my community of friends and family. It was always a taboo topic, an area that we never touched. People were labeled as “crazy” and serious situations were swept under the rug. Seldom was I offered empathy or support. [excerpt]


Perceptions And Experiences Of Perinatal Mental Disorders In Rural, Predominantly Ethnic Minority Communities In Northern Vietnam, Daniel Abrams, Liem T. Nguyen, Jill Murphy, Younji Lee, Nhu K. Tran, David Wiljer Feb 2016

Perceptions And Experiences Of Perinatal Mental Disorders In Rural, Predominantly Ethnic Minority Communities In Northern Vietnam, Daniel Abrams, Liem T. Nguyen, Jill Murphy, Younji Lee, Nhu K. Tran, David Wiljer

Dartmouth Scholarship

Background: Preliminary research has suggested that perinatal mental disorders (PMDs), including post-partum depression, are prevalent in Vietnam. However the extent to which these disorders are recognized at the community level remains largely undocumented in the literature. PMDs have also never been investigated within Vietnam’s significant ethnic minority populations, who are known to bear a greater burden of maternal and infant health challenges than the ethnic majority. Objective: To investigate knowledge and perceptions of PMDs and their treatments at the community level in a rural, predominantly ethnic minority region of northern Vietnam.


Local Health Departments’ Level Of Engagement In Population Mental Health Promotion, Jonathan Purtle, Ann C. Klassen, Jennifer Kolker, Rachel M. Peters, James W. Buehler Feb 2016

Local Health Departments’ Level Of Engagement In Population Mental Health Promotion, Jonathan Purtle, Ann C. Klassen, Jennifer Kolker, Rachel M. Peters, James W. Buehler

Frontiers in Public Health Services and Systems Research

Background: Mental health conditions are highly prevalent in the U.S. and are associated with physical health problems. Federal initiatives recognize mental health as a public health priority, and local health departments (LHDs) have been identified as partners to promote population mental health. Little is known, however, about the extent to which LHDs address mental health or how LHD officials perceive mental health as a public health concern.

Purpose: To describe the cumulative level of LHDs’ engagement in activities to address population mental health and explore how LHD officials perceive their roles in promoting it.

Methods: Module 2 of the 2013 …


Psychiatric Boarding In New Hampshire: Violation Of A Statutory Right To Treatment, James A. Mcclure Feb 2016

Psychiatric Boarding In New Hampshire: Violation Of A Statutory Right To Treatment, James A. Mcclure

The University of New Hampshire Law Review

[Excerpt] "New Hampshire law provides for the involuntary commitment of a patient such as Jane when she is a danger to herself or others as a result of mental illness. The patient has a right to treatment under N.H. Rev. Stat. Ann. § 135-C:1, et seq. Specifically, the patient should receive "adequate and humane treatment" pursuant to an "individual service plan" and "in the least restrictive environment necessary." However, appropriate facilities often are not available for patients waiting in emergency rooms, and patients can become trapped for hours or even days. This phenomenon is called "psychiatric boarding."

New Hampshire is …


A Nursing Approach To Self-Management Education For Individuals With Mental Illness And Diabetes, Edna Fuentes-Casiano, Martha Sajatovic Feb 2016

A Nursing Approach To Self-Management Education For Individuals With Mental Illness And Diabetes, Edna Fuentes-Casiano, Martha Sajatovic

Faculty Scholarship

Patients with serious mental illness (SMI) and diabetes often seek care in primary care settings and have worse health outcomes than patients who have either illness alone. Individual, provider, and system-level barriers present challenges to addressing both psychiatric and medical comorbidities. This article describes the feasibility, acceptability, and implementation of Targeted Training and Illness Management (TTIM), a self-management intervention delivered by trained nurse educators and peer educators to groups of individuals with SMI and diabetes to improve self-management of both diseases. TTIM is intended to be delivered in a primary care setting. Findings are intended to support the future development …


Role Of Pharmacogenetics In Improving The Safety Of Psychiatric Care By Predicting The Potential Risks Of Mania In Cyp2d6 Poor Metabolizers Diagnosed With Bipolar Disorder., Santiago Sánchez-Iglesias, Virginia García-Solaesa, Belén García-Berrocal, Almudena Sanchez-Martín, Carolina Lorenzo-Romo, Tomás Martín-Pinto, Andrea Gaedigk, José Manuel González-Buitrago, María Isidoro-García Feb 2016

Role Of Pharmacogenetics In Improving The Safety Of Psychiatric Care By Predicting The Potential Risks Of Mania In Cyp2d6 Poor Metabolizers Diagnosed With Bipolar Disorder., Santiago Sánchez-Iglesias, Virginia García-Solaesa, Belén García-Berrocal, Almudena Sanchez-Martín, Carolina Lorenzo-Romo, Tomás Martín-Pinto, Andrea Gaedigk, José Manuel González-Buitrago, María Isidoro-García

Manuscripts, Articles, Book Chapters and Other Papers

One of the main concerns in psychiatric care is safety related to drug management. Pharmacogenetics provides an important tool to assess causes that may have contributed the adverse events during psychiatric therapy. This study illustrates the potential of pharmacogenetics to identify those patients for which pharmacogenetic-guided therapy could be appropriate. It aimed to investigate CYP2D6 genotype in our psychiatric population to assess the value of introducing pharmacogenetics as a primary improvement for predicting side effects.A broad series of 224 psychiatric patients comprising psychotic disorders, depressive disturbances, bipolar disorders, and anxiety disorders was included. The patients were genotyped with the AmpliChip …