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Articles 151 - 180 of 556
Full-Text Articles in Mental and Social Health
The Impact Of A Crisis Intervention Team Program On Psychiatric Boarding, Kurtis Hooks
The Impact Of A Crisis Intervention Team Program On Psychiatric Boarding, Kurtis Hooks
Counseling & Human Services Theses & Dissertations
Psychiatric boarding is the phenomenon of housing individuals in emergency departments while awaiting access to mental health services in the community. The expansion of psychiatric boarding is attributed to continued deinstitutionalization and under-resourcing of mental health services. Psychiatric boarding is also associated with deleterious outcomes for individuals in need of access to behavioral health services, facilities. There is limited research on programmatic efforts to reduce psychiatric boarding as it pertains to Crisis Intervention Team programs colocated in medical settings. Crisis Intervention Team (CIT) programs are community-based, multi-stakeholder partnerships that include dedicated assessment centers crisis response and referral. This study utilized …
Injury-Related Fear In Individuals With Chronic Ankle Instability, Ashley Marie Brawford Suttmiller
Injury-Related Fear In Individuals With Chronic Ankle Instability, Ashley Marie Brawford Suttmiller
Rehabilitation Sciences Theses & Dissertations
About 40% of individuals who suffer a lateral ankle sprain develop chronic ankle instability (CAI). The mechanisms for developing CAI is believed to be multi-factorial, however, most literature has focused on the physical manifestations of the condition, leaving our understanding of psychological manifestations of the condition fairly unclear. Injury-related fear has been identified as a psychological factor that may be relevant to the condition, but our understanding is limited. Therefore, the purpose of this dissertation was to better understand injury-related fear in patients with CAI through three studies.
The first study systematically reviewed the literature to understand differences in injury-related …
Effect Of A 2-Week Relaxing Music Intervention On Anxiety, Stress, And Gut Symptoms In Aerobic Exercisers, Halie Marisa Maass
Effect Of A 2-Week Relaxing Music Intervention On Anxiety, Stress, And Gut Symptoms In Aerobic Exercisers, Halie Marisa Maass
Human Movement Studies & Special Education Theses & Dissertations
The purpose of this study was to determine the impact of a two-week relaxing music intervention on stress, anxiety, and gastrointestinal (GI) symptoms in exercisers with at least mild anxiety and exercise-related GI symptoms. Block randomization was used to allocate 15 women and two men into control (n = 8) or intervention (n = 9) groups following a one-week baseline. During the baseline period, participants recorded details of their aerobic exercise sessions and discomfort with GI symptoms (nausea, regurgitation/reflux, stomach fullness, bloating, abdominal cramps, gas, the urge to defecate). Following randomization, both groups tracked these same details for two additional …
Site Supervisors' Perspectives On Supervision Of Counselor Trainees In Integrated Behavioral Health (Ibh) Settings: A Q Methodology Approach, Yeşim Giresunlu
Site Supervisors' Perspectives On Supervision Of Counselor Trainees In Integrated Behavioral Health (Ibh) Settings: A Q Methodology Approach, Yeşim Giresunlu
Counseling & Human Services Theses & Dissertations
Integrated Behavioral Health (IBH) is an integrated care approach where primary care and mental health providers work together to address the medical and behavioral health needs of the patients, or clients (Unützer et al., 2012). An increasing number of clinical mental health counselors are providing services in IBH settings and experiencing challenges with navigating unique aspects of their work in these complex systems. Clinical supervision in these settings appears as a critical resource for mental health counselor trainees (supervisees). However, we have very limited knowledge on clinical supervision provided to supervisees at IBH settings. An exploration of site supervisors’ supervision …
Incivility Of Coworker Behaviors And Minority Firefighters’ Belongingness In The Workplace, Alyssa Reiter
Incivility Of Coworker Behaviors And Minority Firefighters’ Belongingness In The Workplace, Alyssa Reiter
Counseling & Human Services Theses & Dissertations
Research with firefighters continues to indicate that this population is particularly vulnerable to development of mental health conditions as a result of their professional roles (International Association of Firefighters [IAFF], 2019; Stanley et al., 2017; Substance Abuse and Mental Health Services Administration [SAMHSA], 2018) and minority firefighters may be at heightened risk as a result of their experiences within the fire service. An answer to this concern may lie in the exploration of belonging and uncivil behaviors, as research has demonstrated that belonging in the workplace serves to reduce mental health symptoms and enhance an individual’s ability to cope with …
The Role Of Athletic Identity In General Mental Health And Alcohol-Related Help-Seeking Intentions Of College Students, Michael Grant Young
The Role Of Athletic Identity In General Mental Health And Alcohol-Related Help-Seeking Intentions Of College Students, Michael Grant Young
Psychology Theses & Dissertations
Young adults are vulnerable to a range of mental health concerns and tend to drink in high quantities and tend to not seek help for these concerns. Specifically, college students involved in athletics tend to have low help-seeking rates—though help-seeking research for this population is relatively limited. Athletic identity (i.e., identification with the athlete role) is a relevant construct for examining this population, however little is known about its association with help-seeking beliefs and ideas. This study examines: (1) the association between athletic identity and help-seeking intentions for both mental health and alcohol use concerns, (2) the association between …
Body Dissatisfaction And Disordered Eating Among College Women’S Social Networks: An Investigation Of Perceived Changes Following A Dissonance-Based Body Image Intervention, Rachel I. Macintyre
Body Dissatisfaction And Disordered Eating Among College Women’S Social Networks: An Investigation Of Perceived Changes Following A Dissonance-Based Body Image Intervention, Rachel I. Macintyre
Psychology Theses & Dissertations
Body dissatisfaction is associated with numerous health consequences and is pervasive among college women. Effective interventions exist that reduce body dissatisfaction in college women by helping them resist sociocultural pressures to conform to the appearance ideal, such as the Body Project. Yet research is limited on whether social and behavioral processes help participants reduce their engagement in sociocultural appearance-ideal messages and contribute to the intervention’s effectiveness. The primary purpose of the present study was to examine these social and behavioral processes, including the changes in college women’s social networks associated with their participation in the Body Project. Undergraduate and graduate …
An Exploratory Study Of Older Adults’ Emotions To Social Isolation And Their Coping Activities During Covid-19 Pandemic, Letrice Samuels, Michele Kekeh, Muge Akpinar-Elci
An Exploratory Study Of Older Adults’ Emotions To Social Isolation And Their Coping Activities During Covid-19 Pandemic, Letrice Samuels, Michele Kekeh, Muge Akpinar-Elci
College of Health Sciences Posters
Amidst the COVID-19 pandemic, older adults are advised to remain in their homes and personal spaces since they are at greater risk for COVID-19 related illnesses, hospitalizations, and deaths. Health professionals and caregivers are concerned that preventative measures, especially social isolation, may have long-term psychological and age-related effects among older adults. A survey prepared by the Center for Global Health at Old Dominion University, in collaboration with Healthy Chesapeake Inc., assessed social isolation, associated emotions, and daily coping activities of older adults in Chesapeake, Virginia. The target population included senior residents of the Cambridge Square Apartments, where Healthy Chesapeake Inc. …
Burnout, Self-Efficacy, And Coping Strategies Among College Faculty, Jordan M. Ball
Burnout, Self-Efficacy, And Coping Strategies Among College Faculty, Jordan M. Ball
Psychology Theses & Dissertations
Due to the changing college environment, university faculty are faced with a serious burden to support their university. University faculty are expected to satisfy numerous job demands, and these demands in turn lead to burnout, a chronic response to job stressors. Burnout is an essential component of occupational research as it relates to other negative outcomes, such as turnover and decreased performance. Because of this, it behooves both faculty and universities to employ methods that decrease burnout. Research concerning other populations indicates that certain personal resources can decrease burnout. Therefore, the current study seeks to determine if coping strategies and …
Initial Development Of The Escala De Fortaleza En Jóvenes Para Padres, David Moran
Initial Development Of The Escala De Fortaleza En Jóvenes Para Padres, David Moran
Counseling & Human Services Theses & Dissertations
National statistics indicate substantial mental health and academic challenges experienced by a sizable proportion of Hispanic children and adolescents in American school settings. School counselors can provide culturally responsive supports to this population and would benefit from contextually grounded, ecologically valid assessments that focus on the positive development of Hispanic children and adolescents. To address this instrumentation gap, this study sought to develop initial items for the Escala de Fortaleza en Jóvenes para Padres in both English and Spanish. A qualitative approach was implemented to explore the perceptions of Hispanic parents/caregivers of their child or adolescent’s resiliency. Eight Hispanic parents …
Reducing Objectification Could Tackle Stigma In The Covid-19 Pandemic: Evidence From China, Youli Chen, Jiahui Jin, Xiangyang Zhang, Qi Zhang, Weizhen Dong, Chun Chen
Reducing Objectification Could Tackle Stigma In The Covid-19 Pandemic: Evidence From China, Youli Chen, Jiahui Jin, Xiangyang Zhang, Qi Zhang, Weizhen Dong, Chun Chen
Community & Environmental Health Faculty Publications
Stigmatization associated with the coronavirus disease 2019 (COVID-19) is expected to be a complex issue and to extend into the later phases of the pandemic, which impairs social cohesion and relevant individuals' well-being. Identifying contributing factors and learning their roles in the stigmatization process may help tackle the problem. This study quantitatively assessed the severity of stigmatization against three different groups of people: people from major COVID-19 outbreak sites, those who had been quarantined, and healthcare workers; explored the factors associated with stigmatization within the frameworks of self-categorization theory and core social motives; and proposed solutions to resolve stigma. The …
Income-Related Health Inequality Among Chinese Adults During The Covid-19 Pandemic: Evidence Based On An Online Survey, Peng Nie, Lanlin Ding, Zhou Chen, Shiyong Liu, Qi Zhang, Zumin Shi, Lu Wang, Hong Xue, Gordon G. Liu, Youfa Wang
Income-Related Health Inequality Among Chinese Adults During The Covid-19 Pandemic: Evidence Based On An Online Survey, Peng Nie, Lanlin Ding, Zhou Chen, Shiyong Liu, Qi Zhang, Zumin Shi, Lu Wang, Hong Xue, Gordon G. Liu, Youfa Wang
Community & Environmental Health Faculty Publications
BACKGROUND: Partial- or full-lockdowns, among other interventions during the COVID-19 pandemic, may disproportionally affect people (their behaviors and health outcomes) with lower socioeconomic status (SES). This study examines income-related health inequalities and their main contributors in China during the pandemic.
METHODS: The 2020 China COVID-19 Survey is an anonymous 74-item survey administered via social media in China. A national sample of 10,545 adults in all 31 provinces, municipalities, and autonomous regions in mainland China provided comprehensive data on sociodemographic characteristics, awareness and attitudes towards COVID-19, lifestyle factors, and health outcomes during the lockdown. Of them, 8448 subjects provided data for …
A Qualitative Examination Of The Preparedness Of African American Pastors To Address Issues Of Addiction, Shuntay Tarver, Chaniece Winfield, Judith Preston, Alexis Wilkerson, Pastor Isaac Shorter
A Qualitative Examination Of The Preparedness Of African American Pastors To Address Issues Of Addiction, Shuntay Tarver, Chaniece Winfield, Judith Preston, Alexis Wilkerson, Pastor Isaac Shorter
Counseling & Human Services Faculty Publications
This study qualitatively explored the preparedness of African American pastors to meet the needs of parishioners with addictions. Findings indicated that African American pastors do not always perceive themselves to be prepared to address issues of addiction, and existing cultural barriers challenge collaboration between human services practitioners and African American pastors. Findings also revealed that despite existing cultural barriers, African American pastors are willing to collaborate with professionals who offer educational opportunities in culturally relevant ways. Human services professionals’ ability to understand cultural nuances of African American pastors is of paramount concern to effectively enhance the quality of life for …
Maternal Depression Trajectories And Child Bmi In A Multi-Ethnic Sample: A Latent Growth Modeling Analysis, Charlotte V. Farewell, Ryley Donohoe, Zaneta Thayer, James Paulson, Jacinda Nicklas, Caroline Walker, Karen Waldie, Jenn A. Leiferman
Maternal Depression Trajectories And Child Bmi In A Multi-Ethnic Sample: A Latent Growth Modeling Analysis, Charlotte V. Farewell, Ryley Donohoe, Zaneta Thayer, James Paulson, Jacinda Nicklas, Caroline Walker, Karen Waldie, Jenn A. Leiferman
Psychology Faculty Publications
Background
Perinatal (antenatal and postpartum) depression impacts approximately 12% of mothers. Perinatal depression can impact everyday functioning for mothers, and the relationship with, and development of, their children. The purpose of this study was to investigate depression trajectories from the antenatal period through 54-months postpartum and associations with child body mass index at 54-months postpartum.
Methods
This study applied latent growth modeling to the Growing Up in New Zealand study, which is a longitudinal pregnancy cohort study that provides nationally representative-level data, to investigate associations between depression at three time points (antenatal, 9-months postpartum, 54-months postpartum) and child body mass …
Minority Stress And Alcohol Use In Sexual Minority Women's Daily Lives, Robin J. Lewis, Kelly A. Romano, Sarah J. Ehlke, Cathy Lau-Barraco, Cassidy M. Sandoval, Douglas J. Glenn, Kristin E. Heron
Minority Stress And Alcohol Use In Sexual Minority Women's Daily Lives, Robin J. Lewis, Kelly A. Romano, Sarah J. Ehlke, Cathy Lau-Barraco, Cassidy M. Sandoval, Douglas J. Glenn, Kristin E. Heron
Psychology Faculty Publications
No abstract provided.
A Model Of Individual, Relationship, And Societal Factors And Mental Health And Well-Being In Partnered Sexual Minority Women: The Central Role Of Relationship Satisfaction, Charlotte A. Dawson
A Model Of Individual, Relationship, And Societal Factors And Mental Health And Well-Being In Partnered Sexual Minority Women: The Central Role Of Relationship Satisfaction, Charlotte A. Dawson
Psychology Theses & Dissertations
Sexual minority women (SMW) are at increased risk for mental health disorders, substance abuse, and physical health problems compared to heterosexual women. For heterosexual individuals, romantic relationships have been found to be protective against a variety of health issues. Less research, however, has focused on the association between romantic relationships and health in same-sex couples. The purpose of this study was to examine the potential protective nature of being in a relationship for SMW and to test a model investigating the central role of relationship satisfaction in the association between individual, relationship, and societal factors and mental health and well-being …
The Effects Of Military Sexual Trauma And Depressive Symptoms On Reintegration, Rachel L. Davies
The Effects Of Military Sexual Trauma And Depressive Symptoms On Reintegration, Rachel L. Davies
Psychology Theses & Dissertations
Reintegration is a challenge for many veterans returning to civilian roles after military service. Difficulties range from an assortment of issues such as self-care to community participation. Military sexual trauma may be an experience that alters or changes veterans and result in difficulty in reintegration. Specifically, it was predicted that military sexual trauma would indirectly affect reintegration, via depressive symptoms. In addition, locus of control was predicted to play a role in how military sexual trauma impacts reintegration with external locus of control acting as a buffer. Participants were a cross-sectional community sample of both female veterans who reported having …
Group Treatment Effectiveness For Substance Use Disorders: Abstinence Vs. Harm Reduction, Jill D. Parramore
Group Treatment Effectiveness For Substance Use Disorders: Abstinence Vs. Harm Reduction, Jill D. Parramore
Counseling & Human Services Theses & Dissertations
The purpose of this systematic review and meta-analysis was to compare group treatment effectiveness for substance use disorders within the U.S. across treatment philosophies as it relates to the primary research question, Is there a significant difference of group treatment effectiveness between Abstinence and Harm Reduction treatment philosophies? It was hypothesized that group treatment will remain an effective intervention to treat substance use disorders between treatment philosophies and that no significant differences exist between-group comparisons. The aim of this study is to provide evidence of treatment effectiveness that will ultimately improve treatment outcomes for substance use disorders, provide guidance for …
Coping Self-Efficacy As A Potential Moderator Of The Relationship Between Sexual Orientation And Negative Mental Health Outcomes, James M. Macchia
Coping Self-Efficacy As A Potential Moderator Of The Relationship Between Sexual Orientation And Negative Mental Health Outcomes, James M. Macchia
Psychology Theses & Dissertations
Sexual minority individuals (i.e., those who identify as a sexual orientation other than heterosexual) have consistently been linked to an increased risk of negative mental health outcomes. The process of coping can impact the content and severity of said outcomes, and one’s ability to cope is often predicted by the concept known as coping self-efficacy (i.e., one’s belief in his or her ability to cope). This study aimed to assess the effects of sexual orientation, coping self-efficacy, and their interactions on mental health by looking at different aspects of coping self-efficacy as potential moderating variables. Self-perceptions of coping skills were …
Investigating The Impact Of The Fava Well-Being Protocol On Perceived Stress And Psychological Well-Being With At-Promise High School Students, Renee L. Fensom
Investigating The Impact Of The Fava Well-Being Protocol On Perceived Stress And Psychological Well-Being With At-Promise High School Students, Renee L. Fensom
Counseling & Human Services Theses & Dissertations
An elevation in stress levels can be caused by many contributing factors, which can ultimately interfere with the learning of young people. Fortunately, an increase in well being can help promote resilience, creating a buffer to stress. Therefore, the current study investigated the influence of a positive psychology intervention aimed at lowering perceived stress and increasing well-being among at-promise students. The theoretical framework for this study was based on Ryff’s Model of Psychological Well-Being (PWB). The specific intervention used was the Well-being Therapy School Protocol developed by Fava and associates, based off of Carol Ryff’s Model of PWB (Fava, 2016). …
Mindfulness And Its Impact On Adaptive Coping And Psychological Well-Being: An Intervention For Undergraduate Students, Charles Bradley Freligh
Mindfulness And Its Impact On Adaptive Coping And Psychological Well-Being: An Intervention For Undergraduate Students, Charles Bradley Freligh
Psychology Theses & Dissertations
The concept of mindfulness has been shown to positively impact psychological well-being, and one application of mindfulness-based interventions has been the development and implementation of courses specifically for college students, a population that has been shown to be particularly vulnerable to the negative impacts of stress. While these interventions have displayed beneficial outcomes, the mechanisms of how mindfulness exerts its impact remain unclear. One potential mechanism of mindfulness’ enhancement of well-being may be through its cultivation of an adaptive coping style in which an individual becomes more likely to approach and investigate stressors rather than avoid them. In this study, …
Minority Counselor Multicultural Competence In The Current Sociopolitical Climate, Kathleen Brown
Minority Counselor Multicultural Competence In The Current Sociopolitical Climate, Kathleen Brown
Counseling & Human Services Theses & Dissertations
A key component of professional orientation in the field of mental health is the ability to provide counseling that is culturally competent. Counselor preparatory education, ethical codes, professional organizations and regulating bodies recognize cultural competence as a cornerstone of clinical practice. It is especially important during a time in which cultural and racial minorities combat a tumultuous sociopolitical climate. American society has seen an exponential rise in anxiety, depression, and helplessness secondary to the 2016 Presidential Election. For minority counselors, providing multiculturally competent counseling in the face of extreme oppression, and during a period of apparent resurgence in overt systemic …
Workshop #6: Psychological Adjustment For The 2020 Hurricane Season During Covid-19 Pandemic: After-Action Report (Aar), Converge Nsf Working Group, Joshua G. Behr, Wie Yusuf, Jennifer Marshall, Elizabeth Dunn
Workshop #6: Psychological Adjustment For The 2020 Hurricane Season During Covid-19 Pandemic: After-Action Report (Aar), Converge Nsf Working Group, Joshua G. Behr, Wie Yusuf, Jennifer Marshall, Elizabeth Dunn
Presentations, Lectures, Posters, Reports
Participants in the CONVERGE COVID-19 Working Group’s Workshop #6 on Psychological Adjustment breakout sessions discussed the critical threats to psychological health and well-being facing shelter staff, volunteers, and clients in the 2020 hurricane season.
It is widely recognized that people are approaching the 2020 hurricane season under unusual levels of stress. The COVID-19 pandemic has created chronic stressors that individuals are already managing in addition to addressing new acute fears like –will I get sick if I go to a shelter? These new and exacerbated stressors are a risk for higher levels of burnout, compassion fatigue, and ill-being. …
Preferences In Information Processing, Marginalized Identity, And Non-Monogamy: Understanding Factors In Suicide-Related Behavior Among Members Of The Alternative Sexuality Community, Robert J. Cramer, Jennifer Langhinrichsen-Rohling, Andrea R. Kaniuka, Corrine N. Wilsey, Annelise Mennicke, Susan Wright, Erika Montanaro, Jessamyn Bowling, Kristin E. Heron
Preferences In Information Processing, Marginalized Identity, And Non-Monogamy: Understanding Factors In Suicide-Related Behavior Among Members Of The Alternative Sexuality Community, Robert J. Cramer, Jennifer Langhinrichsen-Rohling, Andrea R. Kaniuka, Corrine N. Wilsey, Annelise Mennicke, Susan Wright, Erika Montanaro, Jessamyn Bowling, Kristin E. Heron
Psychology Faculty Publications
Suicide-related behavior (SRB) is a mental health disparity experienced by the alternative sexuality community. We assessed mental health, relationship orientation, marginalized identities (i.e., sexual orientation minority, gender minority, racial minority, ethnic minority, and lower education), and preferences in information processing (PIP) as factors differentiating lifetime SRB groups. An online cross-sectional survey study was conducted in 2018. Members of the National Coalition for Sexual Freedom (NCSF; n = 334) took part. Bivariate analyses identified the following SRB risk factors: female and transgender/gender non-binary identity, sexual orientation minority identity, lower education, suicide attempt/death exposure, Need for Affect (NFA) Avoidance, depression, and anxiety. …
Novel Method Of Supplementing Current Depression Treatments: Using Autonomous Sensory Meridian Response-Centered Therapy To Improve Constipation-Associated Comorbidity Of Depression, Shivam Patel
Virginias Collegiate Honors Council Conference
One-third of individuals struggling with constipation also suffer chronically from comorbid depression, but the evidently shared etiology has remained relatively ambiguous. This proposed study aims to analyze the role of Autonomous Sensory Meridian Response (ASMR), a newly recorded neural phenomenon that causes relaxing “tingles” from unique “triggers” in a subset of individuals, in altering serotonin (5-HT) levels within the ENS to aid with both depression and constipation. In depressed individuals, reduced 5-HT has been clinically accepted as a key symptom and is frequently treated with ineffective SSRIs. Prospective alternative methods of non-invasive treatment, such as ASMR, would not only aid …
Antidepressants Versus Music Therapy: Which Treatment Is Better For Treating Depression In Parkinson's Disease?, Emaan Dawood
Antidepressants Versus Music Therapy: Which Treatment Is Better For Treating Depression In Parkinson's Disease?, Emaan Dawood
Virginias Collegiate Honors Council Conference
Music and medicine are merging to treat depression in Parkinson’s disease (PD). Antidepressants, the current standard, demonstrate mixed effects in clinical trials, warranting other treatment options. Here, I compare music therapy to antidepressants in the treatment of depression in PD via literature review. Studies of depressed PD patients undergoing music therapy and/or antidepressants were reviewed with attention to variables including depression (on a patient-reported outcome) that were measured pre- and post- therapy. In the music studies, improvements were seen in depression. Methodological inconsistencies across these studies, a paucity of studies, and small sample sizes, however, necessitate more research to reach …
Mental Health Counselors' Perceptions On Preparedness In Integrated Behavioral Healthcare In Underserved Areas, Kyulee Park
Mental Health Counselors' Perceptions On Preparedness In Integrated Behavioral Healthcare In Underserved Areas, Kyulee Park
Counseling & Human Services Theses & Dissertations
Integration of behavioral and primary healthcare (IBH) has been increasingly suggested as a model approach in serving historically marginalized populations, including rural, Healthcare Provider Shortage (HPSA), and Medically Underserved (MUA) communities (Coleman & Patrick, 1976; Wong et al., 2019). However, there is no evidence-based practices in interprofessional education and training for professional mental health counselors to serve as competent practitioners in integrated behavioral healthcare. This study examined the gap in interprofessional and counselor education literature by identifying the lived experiences and perceptions of mental health professionals in integrated settings and assessed the need areas in current counselor education. A phenomenological …
Analysis Of Personality, Suicide, And Self‐Injury In Emerging Adulthood, Amanda C. La Guardia, Robert J. Cramer, Claire N. Bryson, Kelly Emelianchik-Key
Analysis Of Personality, Suicide, And Self‐Injury In Emerging Adulthood, Amanda C. La Guardia, Robert J. Cramer, Claire N. Bryson, Kelly Emelianchik-Key
Community & Environmental Health Faculty Publications
Nonsuicidal self‐injury (NSSI) is a maladaptive coping strategy that is of significant clinical concern for behavioral health professionals in college settings. Relationships between NSSI, acquired capability for suicide, interpersonal cognitions, and five‐factor model personality traits were assessed in a survey‐based study that included 192 young adults in a college setting. Results indicated that those with an affirmative suicide attempt history, greater acquired capability for suicide, and elevated neuroticism had an increased likelihood of lifetime NSSI.
A Genome-Wide Association Study Of Cocaine Use Disorder Accounting For Phenotypic Heterogeneity And Gene–Environment Interaction, Jiangwen Sun, Henry R. Kranzler, Joel Gelernter, Jinbo Bi
A Genome-Wide Association Study Of Cocaine Use Disorder Accounting For Phenotypic Heterogeneity And Gene–Environment Interaction, Jiangwen Sun, Henry R. Kranzler, Joel Gelernter, Jinbo Bi
Computer Science Faculty Publications
Background: Phenotypic heterogeneity and complicated gene-environment interplay in etiology are among the primary factors that hinder the identification of genetic variants associated with cocaine use disorder. Methods: To detect novel genetic variants associated with cocaine use disorder, we derived disease traits with reduced phenotypic heterogeneity using cluster analysis of a study sample (n = 9965). We then used these traits in genome-wide association tests, performed separately for 2070 African Americans and 1570 European Americans, using a new mixed model that accounted for the moderating effects of 5 childhood environmental factors. We used an independent sample (918 African Americans, 1382 European …
Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens
Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens
Computer Science Faculty Publications
Background: Although there have been increasing reports of intentional gabapentin misuse, epidemiological evidence for the phenomenon is limited. The purpose of this study was to determine whether there are pharmacovigilance abuse signals for gabapentin.
Methods: Using FDA Adverse Events Reporting System reports from January 1, 2005 to December 31, 2015, we calculated pharmacovigilance signal measures (i.e., reporting odds ratio, proportional reporting ratio, information component, and empirical Bayes geometric mean) for abuse-related adverse event (AR-AE)-gabapentin pairs. Loglinear modeling assessed the frequency of concurrent reporting of abuse-related and abusespecific AEs (AS-AEs) associated with gabapentin. Findings were compared to a positive (pregabalin) and …