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Articles 151 - 180 of 207

Full-Text Articles in Mental and Social Health

Better Cognitive Control Of Emotional Information Is Associated With Reduced Pro-Inflammatory Cytokine Reactivity To Emotional Stress, Grant S. Shields, Shari Young Kuchenbecker, Sarah D. Pressman, Ken D. Sumida, George M. Slavich Jan 2016

Better Cognitive Control Of Emotional Information Is Associated With Reduced Pro-Inflammatory Cytokine Reactivity To Emotional Stress, Grant S. Shields, Shari Young Kuchenbecker, Sarah D. Pressman, Ken D. Sumida, George M. Slavich

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Stress is strongly associated with several mental and physical health problems that involve inflammation, including asthma, cardiovascular disease, certain types of cancer, and depression. It has been hypothesized that better cognitive control of emotional information may lead to reduced inflammatory reactivity to stress and thus better health, but to date no studies have examined whether differences in cognitive control predict pro-inflammatory cytokine responses to stress. To address this issue, we conducted a laboratory-based experimental study in which we randomly assigned healthy young-adult females to either an acute emotional stress (emotionally evocative video) or no-stress (control video) condition. Salivary levels of …


Adult Relationships In Multiple Contexts And Associations With Adolescent Mental Health, Gordon Capp, Ruth Berkowitz, Kate Sullivan, Ron Avi Astor, Kris T. De Pedro, Tamika D. Gilreath, Eric Rice Jan 2016

Adult Relationships In Multiple Contexts And Associations With Adolescent Mental Health, Gordon Capp, Ruth Berkowitz, Kate Sullivan, Ron Avi Astor, Kris T. De Pedro, Tamika D. Gilreath, Eric Rice

Education Faculty Articles and Research

Purpose: Adult relationships provide critical support for adolescents because of their potential to foster positive development and provide protective influences. Few studies examine multiple ecological layers of adult relationships in connection with well-being and depression. This study examines the influence of relationships from multiple contexts for adolescents and their mental health.
Method: Data from the 2011 California Healthy Kids Survey was used for this analysis; a sample of 7th-, 9th-, and 11th-grade students (N = 14,931) was drawn from 6 school districts in Southern California.
Results: Regression analyses revealed that parent, teacher, and community adult support were …


Knowledge, Attitudes, And Intentions Toward Fertility Awareness And Oocyte Cryopreservation Among Obstetrics And Gynecology Resident Physicians, L. Yu, Brennan Peterson, M. C. Inhorn, Julia K. Boehm, P. Patrizio Dec 2015

Knowledge, Attitudes, And Intentions Toward Fertility Awareness And Oocyte Cryopreservation Among Obstetrics And Gynecology Resident Physicians, L. Yu, Brennan Peterson, M. C. Inhorn, Julia K. Boehm, P. Patrizio

Marriage and Family Therapy Faculty Articles and Research

STUDY QUESTION What knowledge, attitudes and intentions do US obstetrics and gynecology (OB/GYN) residents have toward discussing age-related fertility decline and oocyte cryopreservation with their patients?

SUMMARY ANSWER Most OB/GYN residents believe that age-related fertility decline, but not oocyte cryopreservation, should be discussed during well-woman annual exams; furthermore, nearly half of residents overestimated the age at which female fertility markedly declines.

WHAT IS KNOWN ALREADY Oocyte cryopreservation can be utilized to preserve fertility potential. Currently, no studies of US OB/GYN residents exist that question their knowledge, attitudes, and intentions toward discussing age-related fertility decline and oocyte cryopreservation with patients.

STUDY …


Predictive Factors Of Patient Satisfaction With Pharmacy Services In South Korea: A Cross-Sectional Study Of National Level Data, Sunkyung Lee, Onyeka P. Godwin, Kyungah Kim, Euni Lee Nov 2015

Predictive Factors Of Patient Satisfaction With Pharmacy Services In South Korea: A Cross-Sectional Study Of National Level Data, Sunkyung Lee, Onyeka P. Godwin, Kyungah Kim, Euni Lee

Pharmacy Faculty Articles and Research

Objectives
Patient satisfaction has emerged as a prerequisite to improving patients’ health behaviors leading to better health care outcomes. This study was to identify predictive determinants for patient satisfaction with pharmacy services using national-level data.

Methods
A cross-sectional evaluation was conducted using 2008 Korean National Health and Nutrition Examination Survey (KNHANES) data. To assess the predictive factors for patient satisfaction with pharmacy services, an ordinal logistic regression model was conducted adjusting for patient characteristics, clinical comorbidities, and perception of health.

Results
A total of 9,744 people, a representative sample of 48.2 million Koreans, participated in the 2008 KNHANES, of whom …


#Narcissus, Lauren Potts May 2015

#Narcissus, Lauren Potts

Student Scholar Symposium Abstracts and Posters

My senior BFA exhibition is a project bringing awareness and reflection to the college subculture of drinking. I am creating a large installation (approx. 10x20ft) made out of over 4,000 red plastic cups in the shape of a Catholic Church altar. The cups are stacked and glued together in order to create patterns to separate the forms of the altar (three stairs, columns, the facade arches). The installation is shown at Chapman University's Guggenheim Gallery and must be site specific in order to reflect the nature of its existence and purpose. The installation reflects a parallel between forms of ritual: …


Characterizing Psychological Management Practices Of College And University Athletic Trainers In Orange, California, Hannah L. Alexander, Paulina Tselikis, Michelle A. Cleary, Sara L. Nottingham, Jason Bennett May 2015

Characterizing Psychological Management Practices Of College And University Athletic Trainers In Orange, California, Hannah L. Alexander, Paulina Tselikis, Michelle A. Cleary, Sara L. Nottingham, Jason Bennett

Student Scholar Symposium Abstracts and Posters

An increase in the prevalence, types, and severity of psychological disorders among adolescents and young adults is being recognized. A multidisciplinary team approach to address mental health concerns among student-athletes, including well-developed referral and management plans, is important in the health care setting. Athletic trainers are often the first to notice subtle changes indicative of psychopathology, and have the ability to appropriately intervene and refer student-athletes as necessary. The purpose of this study was to investigate the psychological management practices of college and university athletic trainers in Orange, California. A descriptive exploratory online questionnaire was used to obtain information regarding …


College Students' Communication About Nonmedical Use Of Prescription Stimulants: Applying The Theory Of Planned Behavior, Ana Andreoli, Darren Breese, Kylie Deschenes, Lindsey Sarver May 2015

College Students' Communication About Nonmedical Use Of Prescription Stimulants: Applying The Theory Of Planned Behavior, Ana Andreoli, Darren Breese, Kylie Deschenes, Lindsey Sarver

Student Scholar Symposium Abstracts and Posters

The study examines college students' communication surrounding nonmedical use of prescription stimulants (NPS). Using a hypothetical scenario, the researchers will employ the Theory of Planned Behavior to investigate if students' attitudes and perceived social norms affect their intent to intervene on behalf of a friend who is engaging in what they believe to be excessive NPS. College students’ will complete anonymous web-based surveys, reporting on each of the study variables as well as demographic information. Self-reports of both perceived and actual knowledge of engaging in NPS, as well as students' levels of communication health literacy, will also be collected as …


Efficacy Of The Picture Exchange Communication Systemin Children With Autism Spectrum Disorder, Reagan Blason May 2015

Efficacy Of The Picture Exchange Communication Systemin Children With Autism Spectrum Disorder, Reagan Blason

Student Scholar Symposium Abstracts and Posters

The increasing diagnoses of Autism Spectrum Disorder (ASD) each year affect many families worldwide and are a major concern to therapists, healthcare workers, and educators. Many children diagnosed with ASD will never go on to develop functional speech or will have limited communication, as well as impaired social-communication skills. Limited communication makes education and therapy difficult for these children and their caregivers. Language therapy and interventions aim to improve social-communication and speech in these children, so it is crucial to find the most efficient interventions. The Picture Exchange Communication System (PECS) is a common tool used to assist communication in …


Teacher Narratives And Student Engagement Testing Narrative Engagement Theory In Drug Prevention Education, Michelle Miller-Day, Michael L. Hecht, Janice L. Krieger, Jonathan Pettigrew, Young Ju Shin, John L. Graham May 2015

Teacher Narratives And Student Engagement Testing Narrative Engagement Theory In Drug Prevention Education, Michelle Miller-Day, Michael L. Hecht, Janice L. Krieger, Jonathan Pettigrew, Young Ju Shin, John L. Graham

Communication Faculty Articles and Research

Testing narrative engagement theory, this study examines student engagement and teachers’ spontaneous narratives told in a narrative-based drug prevention curriculum. The study describes the extent to which teachers share their own narratives in a narrative-based curriculum, identifies dominant narrative elements, forms and functions, and assesses the relationships among teacher narratives, overall lesson narrative quality, and student engagement. One-hundred videotaped lessons of the keepin’ it REAL drug prevention curriculum were coded and the results supported the claim that increased narrative quality of a prevention lesson would be associated with increased student engagement. The quality of narrativity, however, varied widely. Implications of …


Fertility Counseling For Couples, Brennan Peterson Apr 2015

Fertility Counseling For Couples, Brennan Peterson

Marriage and Family Therapy Faculty Books and Book Chapters

"The purpose of this chapter is to provide fertility counselors with the tools necessary to effectively assess and treat couples experiencing fertility problems so that these couples can improve their relationships, reduce psychological and infertility related distress, and regain control and direction in their lives. The chapter will outline the challenges unique to couples experiencing infertility, and will integrate several case vignettes which portray common profiles of couples who fertility counselors may encounter. Gender differences in how couples communicate and cope with infertility distress will be presented. The chapter will also examine the impact of infertility on a couple’s sexual …


2nd Place Research Paper: Treatment Of Post-Traumatic Stress Disorder In A Veteran Population: Efficacy Of Complementary And Alternative Medicine Therapies, Brooke D. Snelgrove Apr 2015

2nd Place Research Paper: Treatment Of Post-Traumatic Stress Disorder In A Veteran Population: Efficacy Of Complementary And Alternative Medicine Therapies, Brooke D. Snelgrove

Kevin and Tam Ross Undergraduate Research Prize

It is estimated that a half million veterans from recent deployments in the Middle East conflicts and about 479,000 veterans deployed during the Vietnam War are diagnosed with Post Traumatic Stress Disorder (PTSD). Current treatments are limited by a relatively high frequency of patients who do not continue with their therapy. With increased PTSD diagnosis and limited effectiveness of treatments, there is a growing need to research and develop new therapies to better assist affected service members. The present study assessed the clinical validity of Complementary and Alternative Medicine therapies for the treatment of PTSD symptoms in a military population …


Intentions And Attitudes Towards Parenthood And Fertility Awareness Among Chinese University Students In Hong Kong: A Comparison With Western Samples, C. H. Y. Chan, T. H. Y. Chan, Brennan Peterson, C. Lampic, M. Y. J. Tam Jan 2015

Intentions And Attitudes Towards Parenthood And Fertility Awareness Among Chinese University Students In Hong Kong: A Comparison With Western Samples, C. H. Y. Chan, T. H. Y. Chan, Brennan Peterson, C. Lampic, M. Y. J. Tam

Marriage and Family Therapy Faculty Articles and Research

STUDY QUESTION What are the levels of awareness regarding female fertility and the intentions and attitudes towards parenthood among Chinese university students in Hong Kong compared with their counterparts in the West?

SUMMARY ANSWER Chinese university students in Hong Kong were similarly over-optimistic about the age-related fertility decline, although they were less inclined to have children and undergo fertility treatment compared with their Western counterparts.

WHAT IS KNOWN ALREADY Past studies of highly educated young adults in Europe and the USA have found that they are not sufficiently aware of the age-related decline in female fertility, and falsely believe that …


Adjusting Learning Parameters To Increase Cognitive Resource Allocation In Persons With Alcoholism Risk, Brooke Snelgrove, Taylor Stephens, Yasmin Akbari, Reyn Yoshiura, Lilian Andrade Dec 2014

Adjusting Learning Parameters To Increase Cognitive Resource Allocation In Persons With Alcoholism Risk, Brooke Snelgrove, Taylor Stephens, Yasmin Akbari, Reyn Yoshiura, Lilian Andrade

Student Scholar Symposium Abstracts and Posters

Parental history of alcoholism is associated with increased alcoholism risk in their children. One factor increasing alcoholism risk is the presence of attention and information encoding disruptions in adult children of alcoholics (ACOA) compared to persons who are not ACOAs (NACOA). Alcohol ingestion reduces these disruptions in ACOAs. This study examined whether alterations of information processing parameters can function like alcohol and reduce processing disruptions experienced by the ACOA. Participants were 80 ACOAs and 80 NACOAs, partitioned into four groups of 20 participants. During learning, subjects studied presentations of stimulus items followed by the presentation of associated response items. The …


Increasing Response Time And Response Evaluation Time Compensates For Information Processing Difficulties In Persons At Risk For Alcoholism, Yasmin Akbari Dec 2014

Increasing Response Time And Response Evaluation Time Compensates For Information Processing Difficulties In Persons At Risk For Alcoholism, Yasmin Akbari

Student Scholar Symposium Abstracts and Posters

Parental history of alcoholism is associated with increased alcoholism risk in their children. One factor increasing alcoholism risk is the presence of attention and information encoding disruptions in adult children of alcoholics (ACOA) compared to persons who are not ACOAs (NACOA). Alcohol ingestion reduces these disruptions in ACOAs. This study examined whether alterations of information processing parameters can function like alcohol and reduce processing disruptions experienced by the ACOA.

Participants were 80 ACOAs and 80 NACOAs, partitioned into four groups of 20 participants. During learning, subjects studied presentations of stimulus items followed by the presentation of associated response items. The …


Accommodating Hyperaroused Information Processing In Persons At Risk For Alcoholism, Kellianne Clark, Jaclyn Cutler Dec 2014

Accommodating Hyperaroused Information Processing In Persons At Risk For Alcoholism, Kellianne Clark, Jaclyn Cutler

Student Scholar Symposium Abstracts and Posters

In the search for the factors related to the heightened alcoholism risk in adult children of alcoholics (ACOA), it has been reported that these persons possess a high incidence of attention deficit disorders (ADD) as determined by clinical assessment instruments. However, investigations of alcoholism risk and ADD indicate that, in contrast to the hypoarousal model of ADD, the ACOA’s attention problems represent hyperarousal of attention mechanisms resulting in reduced ability to select and encode relevant information. If true, then unlike persons with ADD, clinical and cognitive assessments of ACOAs would benefit if the ACOA was provided with more time to …


Is Postpartum Depression A Disease Of Modern Civilization?, Jennifer Hahn-Holbrook, Martie Haselton Dec 2014

Is Postpartum Depression A Disease Of Modern Civilization?, Jennifer Hahn-Holbrook, Martie Haselton

Psychology Faculty Articles and Research

Access to calorie-dense foods, medicine, and other comforts has made modern humans healthier than our prehistoric ancestors in many respects. However, the epidemics of obesity, diabetes, and cardiovascular disease suggest that there are also drawbacks to modern living. Here, we address the question of whether the dramatic cultural changes that have occurred over the past century have inflated rates of postpartum depression, adding postpartum depression to the list of diseases of modern civilization. We review evidence from cross-cultural, epidemiological, and experimental studies documenting associations between postpartum depression and modern patterns of early weaning, diets deficient in essential fatty acids, low …


Who Cares? Caregiver Well-Being In Europe, Leah Ruppanner, Georgiana Bostean Aug 2014

Who Cares? Caregiver Well-Being In Europe, Leah Ruppanner, Georgiana Bostean

Sociology Faculty Articles and Research

This paper analyzes a multi-national sample comparing self-reported well-being of those who provide dependent care to that of non-caregivers. We pair individual-level data from the 2004 European Social Survey (ESS) for respondents in 22 nations (n=41,000+) with country-level measures of attitudinal support for co-residential familial caregiving (2007 Eurobarometer), old age and family public transfers (OECD Social Expenditures Database, 2014) and economic development (GDP). Using multi-level modeling, we examine the association between country-level co-residential familial attitudes and public spending and individual-level caregiver well-being, comparing effects by gender. We find that: (1) caregiving is differentially associated with well-being for men and women; …


Severe Depressive Symptoms Predict Individual And Partner Infertility-Related Distress At One-Year Follow-Up, Brennan Peterson, Camilla Sejbaek, Matthew Pirritano, Lone Schmidt Jan 2014

Severe Depressive Symptoms Predict Individual And Partner Infertility-Related Distress At One-Year Follow-Up, Brennan Peterson, Camilla Sejbaek, Matthew Pirritano, Lone Schmidt

Marriage and Family Therapy Faculty Presentations

Poster presentation on whether severe depressive symptoms at baseline are a predictor of individual and partner infertility-related distress after one-year of unsuccessful fertility treatments.


Bipolar Disorder: A Pharmacotherapy Management Overview, Huong Le, Tina Pham, Laura Tsu Jan 2014

Bipolar Disorder: A Pharmacotherapy Management Overview, Huong Le, Tina Pham, Laura Tsu

Pharmacy Faculty Articles and Research

This home-study CPE activity has been developed to educate pharmacists on bipolar disorder and its management using non-pharmacologic and pharmacologic therapies.


Understanding And Treating The Psychosocial Consequences Of Infertility, Arthur L. Greil, Lone Schmidt, Brennan Peterson Jan 2014

Understanding And Treating The Psychosocial Consequences Of Infertility, Arthur L. Greil, Lone Schmidt, Brennan Peterson

Marriage and Family Therapy Faculty Books and Book Chapters

Psychological distress and infertility are linked in a complex pattern, such that distress may be a cause of infertility and reduce the probability of achieving a pregnancy at the same time that infertility may be a cause of psychological distress. Although infertile women are not more likely to be characterized by psychopathology, they are more likely to experience higher levels of distress than comparison groups. Infertile men also experience psychological distress, but women experience more infertility distress than men. Both infertility and its treatment are stressors putting a heavy psychological strain on couple relationships. Whereas there is general agreement about …


Social Compass Curriculum: Three Descriptive Case Studies Of Social Skills Outcomes For Students With Autism, Louanne E. Boyd, Deborah M. Ward Oct 2013

Social Compass Curriculum: Three Descriptive Case Studies Of Social Skills Outcomes For Students With Autism, Louanne E. Boyd, Deborah M. Ward

Engineering Faculty Articles and Research

The Social Compass Curriculum (SCC) was investigated for its effectiveness in improving core social skills in three descriptive case studies of students with autism. Treatment fidelity of the SCC was also measured in the school setting. The Social Responsiveness Scale and the Autism Social Skills Profile were completed by parents to measure pre- and postintervention social skills for three students aged 8 to 11 years who participated in the present multisite pilot study. Fidelity of implementation data were collected via a checklist during observations for three educators who implemented the intervention. Results indicate that the SCC improved core social deficits …


From Kids, Through Kids, To Kids: Examining The Social Influence Strategies Used By Adolescents To Promote Prevention Among Peers, Janice L. Krieger, Samantha Coveleski, Michael L. Hecht, Michelle Miller-Day, John W. Graham, Jonathan Pettigrew, Allison Kootsikas Oct 2013

From Kids, Through Kids, To Kids: Examining The Social Influence Strategies Used By Adolescents To Promote Prevention Among Peers, Janice L. Krieger, Samantha Coveleski, Michael L. Hecht, Michelle Miller-Day, John W. Graham, Jonathan Pettigrew, Allison Kootsikas

Communication Faculty Articles and Research

Recent technological advances have increased the interest and ability of lay audiences to create messages; however, the feasibility of incorporating lay multimedia messages into health campaigns has seldom been examined. Drawing on the principle of cultural grounding and narrative engagement theory, this article seeks to examine what types of messages adolescents believe are most effective in persuading their peers to resist substance use and to provide empirical data on the extent to which audience-generated intervention messages are consistent with the associated campaign philosophy and branding. Data for the current study are prevention messages created by students as part of a …


Narrative Means To Preventative Ends: A Narrative Engagement Framework For Designing Prevention Interventions, Michelle Miller-Day, Michael L. Hecht Oct 2013

Narrative Means To Preventative Ends: A Narrative Engagement Framework For Designing Prevention Interventions, Michelle Miller-Day, Michael L. Hecht

Communication Faculty Articles and Research

This article describes a Narrative Engagement Framework (NEF) for guiding communication-based prevention efforts. This framework suggests that personal narratives have distinctive capabilities in prevention. The article discusses the concept of narrative, links narrative to prevention, and discusses the central role of youth in developing narrative interventions. As illustration, the authors describe how the NEF is applied in the keepin' it REAL adolescent drug prevention curriculum, pose theoretical directions, and offer suggestions for future work in prevention communication.


Human Milk Cortisol Is Associated With Infant Temperament, Katherine R. Grey, Elyssia Poggi Davis, Curt A. Sandman, Laura M. Glynn Jul 2013

Human Milk Cortisol Is Associated With Infant Temperament, Katherine R. Grey, Elyssia Poggi Davis, Curt A. Sandman, Laura M. Glynn

Psychology Faculty Articles and Research

The implications of the biologically active elements in milk for the mammalian infant are largely unknown. Animal models demonstrate that transmission of glucocorticoids through milk influences behavior and modifies brain development in offspring. The aim of this study was to determine the relation between human milk cortisol levels and temperament of the breastfed infant. Fifty-two mother and infant pairs participated when the infants were three-months old. Milk cortisol levels were assessed and each mother completed the Infant Behavior Questionnaire (IBQ), a widely used parent-report measure of infant temperament. Analyses revealed a positive association between milk cortisol and the negative affectivity …


Random Assignment Of Schools To Groups In The Drug Resistance Strategies Rural Project: Some New Methodological Twists, John W. Graham, Jonathan Pettigrew, Michelle Miller-Day, Janice L. Krieger, Jiangxiu Zhou, Michael L. Hecht Jan 2013

Random Assignment Of Schools To Groups In The Drug Resistance Strategies Rural Project: Some New Methodological Twists, John W. Graham, Jonathan Pettigrew, Michelle Miller-Day, Janice L. Krieger, Jiangxiu Zhou, Michael L. Hecht

Communication Faculty Articles and Research

Random assignment to groups is the foundation for scientifically rigorous clinical trials. But assignment is challenging in group randomized trials when only a few units (schools) are assigned to each condition. In the DRSR project, we assigned 39 rural Pennsylvania and Ohio schools to three conditions (rural, classic, control). But even with 13 schools per condition, achieving pretest equivalence on important variables is not guaranteed. We collected data on six important school-level variables: rurality, number of grades in the school, enrollment per grade, percent white, percent receiving free/assisted lunch, and test scores. Key to our procedure was the inclusion of …


The Conceptualization And Communication Of Risk Among Rural Appalachian Adolescents, Jennifer J. Moreland, Janice L. Krieger, Michael L. Hecht, Michelle Miller-Day Jan 2013

The Conceptualization And Communication Of Risk Among Rural Appalachian Adolescents, Jennifer J. Moreland, Janice L. Krieger, Michael L. Hecht, Michelle Miller-Day

Communication Faculty Articles and Research

This study employs a meta-theoretical perspective for examining risk perceptions and behavior in the rural, Appalachian cultural context, an area that remains largely unexplored. In-depth interviews were conducted with 113 rural adolescents to describe how youth conceptualize risk and how risk is communicated in the rural environment. Analyses revealed adolescents viewed behavior as risky when they had personal or vicarious experiences resulting in a loss of control or physical harm. Elements of the rural Appalachian culture including activities, familism, and community ties can both prevent and promote adolescent risk-taking in various forms. This study demonstrates the conceptualization of risk and …


Adapting School-Based Substance Use Prevention Curriculum Through Cultural Grounding: A Review And Exemplar Of Adaptation Processes For Rural Schools, Margaret Colby, Michael L. Hecht, Michelle Miller-Day, Janice L. Krieger, Amy K. Syvertsen, John W. Graham, Jonathan Pettigrew Jan 2013

Adapting School-Based Substance Use Prevention Curriculum Through Cultural Grounding: A Review And Exemplar Of Adaptation Processes For Rural Schools, Margaret Colby, Michael L. Hecht, Michelle Miller-Day, Janice L. Krieger, Amy K. Syvertsen, John W. Graham, Jonathan Pettigrew

Communication Faculty Articles and Research

A central challenge facing twenty-first century community-based researchers and prevention scientists is curriculum adaptation processes. While early prevention efforts sought to develop effective programs, taking programs to scale implies that they will be adapted, especially as programs are implemented with populations other than those with whom they were developed or tested. The principle of cultural grounding, which argues that health message adaptation should be informed by knowledge of the target population and by cultural insiders, provides a theoretical rational for cultural regrounding and presents an illustrative case of methods used to reground the keepin’ it REAL substance use prevention curriculum …


Menthol Binding And Inhibition Of A7-Nicotinic Acetylcholine Receptors, Abrar Ashoor, Jacob C. Nordman, Daniel Veltri, Keun-Hang Susan Yang, Lina T. Al Kury, Yaroslav M. Shuba, Mohamed Magoub, Frank Christopher Howarth, Bassem Sadek, Amarda Shehu, Nadine Kabbani, Murat Oz Jan 2013

Menthol Binding And Inhibition Of A7-Nicotinic Acetylcholine Receptors, Abrar Ashoor, Jacob C. Nordman, Daniel Veltri, Keun-Hang Susan Yang, Lina T. Al Kury, Yaroslav M. Shuba, Mohamed Magoub, Frank Christopher Howarth, Bassem Sadek, Amarda Shehu, Nadine Kabbani, Murat Oz

Mathematics, Physics, and Computer Science Faculty Articles and Research

Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes. The molecular targets of menthol remain poorly defined. In this study we show an effect of menthol on the α7 subunit of the nicotinic acetylcholine (nACh) receptor function. Using a two-electrode voltage-clamp technique, menthol was found to reversibly inhibit α7-nACh receptors heterologously expressed in Xenopus oocytes. Inhibition by menthol was not dependent on the membrane potential and did not involve endogenous Ca2+-dependent Cl− channels, since menthol inhibition remained unchanged by intracellular injection of the Ca2+ chelator BAPTA and perfusion with Ca2+-free bathing solution containing …


Leveraging Family Values To Decrease Unhealthy Alcohol Use In Aging Latino Day Laborers, Homero E. Del Pino, Carolyn Méndez-Luck, Georgiana Bostean, Karina Ramírez, Marlom Portillo, Alison A. Moore Jan 2013

Leveraging Family Values To Decrease Unhealthy Alcohol Use In Aging Latino Day Laborers, Homero E. Del Pino, Carolyn Méndez-Luck, Georgiana Bostean, Karina Ramírez, Marlom Portillo, Alison A. Moore

Sociology Faculty Articles and Research

In one Los Angeles study, 20% of day laborers reported excessive drinking. Older adults are more sensitive to alcohol’s effects, yet heavy drinking persists among Latinos until they are in their 60s. No interventions to reduce heavy drinking exist for aging day laborers. We recruited 14 day laborers aged 50 and older in Los Angeles. We identified their unhealthy alcohol use behaviors and comorbidities and conducted semi-structured interviews to understand their perceptions of unhealthy alcohol use. We found social disadvantages and conditions exacerbated by alcohol use, like depression. Participants were concerned with dying and premature aging, and reported that family …


Placental Corticotropin-Releasing Hormone Mediates The Association Between Prenatal Social Support And Postpartum Depression, Jennifer Hahn-Holbrook, Christine Dunkel Schetter, Chander Arora, Calvin J. Hobel Jan 2013

Placental Corticotropin-Releasing Hormone Mediates The Association Between Prenatal Social Support And Postpartum Depression, Jennifer Hahn-Holbrook, Christine Dunkel Schetter, Chander Arora, Calvin J. Hobel

Psychology Faculty Articles and Research

Three decades of research point to both biological and psychological risk factors for postpartum depression, but very little research integrates the two. This study bridged this gap by testing whether prenatal social support predicted depressive symptoms at 8 weeks postpartum in a multiethnic sample of 210 women and whether the stress hormone placental corticotropinreleasing hormone (pCRH), measured at 19, 29, and 37 weeks’ gestation, mediated this relationship. We found that prenatal family support predicted significantly fewer depressive symptoms postpartum and more gradual increases in pCRH from 29 to 37 weeks’ gestation. Furthermore, steeper increases in pCRH during this same period …