Primary Care Commons^™

Brazilian Longitudinal Study Of Adult Health (Elsa-Brasil): Objectives And Design., Paulo A. Lotufo

Paulo A Lotufo

The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information with respect to the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular diseases and diabetes. In this report, the authors delineate the study's objectives, principal methodological features, and timeline. At baseline, ELSA-Brasil enrolled 15,105 civil servants from 5 universities and 1 research institute. The baseline examination (2008-2010) included detailed interviews, clinical and anthropometric examinations, an oral glucose tolerance test, overnight urine collection, a 12-lead resting electrocardiogram, measurement of carotid intima-media thickness, echocardiography, measurement of pulse wave velocity, hepatic ultrasonography, retinal fundus photography, and an …

Chronic Non-Communicable Diseases In Brazil: Priorities For Disease Management And Research, Bruce B. Duncan, Dora Chor, Estela M. Aquino, Isabela M. Bensenor, J.Geraldo Mill, M.Ines Schmidt, Paulo A. Lotufo, Alvaro Vigo, Sandhi M. Barreto

Paulo A Lotufo

Chronic Non-Communicable Diseases are the main source of disease burden in Brazil. In 2011, the Brazilian Ministry of Health launched the Strategic Plan of Action for Management of Chronic Non-Communicable Diseases focusing on population-based interventions to manage cardiovascular diseases, diabetes, cancer, and chronic respiratory diseases mainly through fi ghting tobacco use, unhealthy diets, physical inactivity and the harmful use of alcohol. Although a signifi cant number of scientifi c studies on chronic diseases and their risk factors have been undertaken in Brazil, few are of cohort design. In this context, the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a cohort …

Elsa-Brasil: Historico [In Portuguese], Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Pufa And Vitamin D And Type 2 Diabetes Inflammatory Markers, Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Measurements Of Adiposity And High Blood Pressure Among Children And Adolescents Living In Belo Horizonte, Paulo A. Lotufo

Paulo A Lotufo

Abstract Objective: To verify an association, if it exists, between obesity and blood pressure raised beyond the 90th percentile in children and adolescents, and to determine the measure of adiposity that best correlates with blood pressure in these subjects. Design: Cross-sectional study. Setting: A school-based study in Belo Horizonte, Brazil. Participants: We selected randomly 1,403 students, aged from 6 to 18 years, from 545,046 students attending 521 public and private schools. Those selected completed the study. Main measures of outcome: We recorded the weight, height, skin fold in the triceps, subscapular, and suprailiac areas, waist and hip circumference, body-mass index, …

Estudo Longitudinal De Saúde Do Adulto -Elsa-Brasil [English], Paulo A. Lotufo

Paulo A Lotufo

Presentation update on September, 2011.

Additional Cardiovascular Risk Factors Associated With Excess Weigth In Children And Adolescents. The Belo Horizonte Heart Study, Paulo A. Lotufo

Paulo A Lotufo

OBJECTIVE: To examine the association of overweight and obesity with physical activity, blood pressure (BP) and serum lipid profiles. METHODS Epidemiologic investigation of 1,450 students, between the ages of 6 and 18, in the city of Belo Horizonte, MG. Data: weight, height, BP, skinfold thickness, waist circumference, physical activity, total cholesterol (TC), LDL-c, HDL-c, and dietary habits. RESULTS The prevalence rates for overweight and obesity were 8.4% and 3.1%, respectively. In relation to the students in the lower quartile (Q1) of the distribution of subscapular skinfold, the students in the upper quartile (Q4) presented a 3.7 times higher risk (odds …

The "Common Soil" Theory: Coronary Disease, Diabetes And Inflammation., Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Framingham Score For Cardiovascular Diseases Among Civil Servantes,Sao Paulo, 1998.[Portuguese], Paulo A. Lotufo

Paulo A Lotufo

Lecture presented the first meeting for a cohort study addressing cardiovascular diseases in Brazil. Hospital Universitario/ Universidade de Sao Paulo, August, 2004.

Screening At Worksite Applying The Framingham Heart Study Score., Paulo A. Lotufo

Paulo A Lotufo

The first evaluation of class of occupation and cardiovascular risk factors in a Brazilian sample of civil servants. 1) context: Cardiovascular diseases are the main causes of death in Brazil. The high-risk approach to cardiovascular risk factors by screening test at worksite is one possible strategy of prevention. 2) objective: to verify the impact of a risk factors screening according to occupational levels. 3) type of study: cross-sectional 4) setting: occupational division of University of Sao Paulo 5) participants: 6,587 employees aged 20 to 69 years-old classified according three occupational grades (non-skilled, both manual and non-manual jobs; technical; faculty). 6) …

Diabetes And All-Cause And Coronary Heart Disease Mortality Among Us Male Physicians, Paulo A. Lotufo, Joann E. Manson

Paulo A Lotufo

Background: While diabetes has long been associated

with increased risk of coronary heart disease (CHD), the

magnitude of risk of diabetes-related CHD is uncertain.

Objective: To evaluate the impact of diabetes and prior

CHD on all-cause and CHD mortality.

Methods: In a prospective cohort study of 91 285 US

male physicians aged 40 to 84 years, participants were

divided into 4 groups: (1) a reference group of 82 247

men free of both diabetes and CHD (previous myocardial

infarction and/or angina) at baseline, (2) 2317 men

with a history of diabetes but not CHD, (3) 5906 men

with a history …

Increasing Obesity In Brazil: Predicting A New Peak Of Cardiovascular Diseases, Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Alcohol Consumption And Risk Of Coronary Heart Disease By Diabetes Status, Paulo A. Lotufo

Paulo A Lotufo

Background—An inverse association between moderate alcohol consumption and coronary heart disease (CHD) has been observed in several epidemiological studies. To assess whether a similar association exists among diabetics, we examined the relation between light to moderate alcohol consumption and CHD in men with and without diabetes mellitus in a prospective cohort study. Methods and Results—A total of 87 938 US physicians (2790 with diagnosed diabetes mellitus) who were invited to participate in the Physicians’ Health Study and were free of myocardial infarction, stroke, cancer, or liver disease at baseline were followed for an average of 5.5 years for death with …