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Full-Text Articles in Medical Specialties
Vital Signs, December 1988, Boonshoft School Of Medicine
Vital Signs, December 1988, Boonshoft School Of Medicine
Vital Signs
A sixteen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.
Vital Signs, April 1988, Boonshoft School Of Medicine
Vital Signs, April 1988, Boonshoft School Of Medicine
Vital Signs
A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.
Atrioventricular Nodal Function In The Immature Canine Heart, Jorge Mccormack, Henry Gelband, Hui Xu, Juan Villafane, Adrienne Stolfi, Arthur S. Pickoff
Atrioventricular Nodal Function In The Immature Canine Heart, Jorge Mccormack, Henry Gelband, Hui Xu, Juan Villafane, Adrienne Stolfi, Arthur S. Pickoff
Medical Education Faculty Publications
Previous studies have suggested that the atrioventricular nodal functional refractory period in the neonate is equal to or shorter than that of the ventricle, providing little or no protection to the ventricle against rapid atrial rates and allowing closely coupled atrial beats to fall within the ventricular vulnerable period. We evaluated atrioventricular node function in 21 mongrel neonatal puppies, 3-15 days old, and 15 adult dogs utilizing intracardiac His bundle recording and stimulation techniques. The mean atrioventricular nodal functional refractory period (173.1 ± 20.0 ms) exceeded both the ventricular effective refractory period (139.5 ± 14.3) and ventricular functional refractory period …
In Vivo Demonstration Of Maturational Changes Of The Chronotropic Response To Α-Adrenergic Stimulation, Jorge Mccormack, Henry Gelband, Juan Villafañe, Hui Xu, Adrienne Stolfi, Arthur S. Pickoff
In Vivo Demonstration Of Maturational Changes Of The Chronotropic Response To Α-Adrenergic Stimulation, Jorge Mccormack, Henry Gelband, Juan Villafañe, Hui Xu, Adrienne Stolfi, Arthur S. Pickoff
Medical Education Faculty Publications
In vitro studies suggest that neonates and adults may have different cardiac chronotropic responses to a-adrenergic stimulation. To investigate these differences in vivo, three groups of dogs were studied. Group I = 12 puppies, ages 3-7 days; group II = 12 puppies ages 8-15 days, and group III = seven adult dogs. Heart rate and blood pressure determinations were made in the control setting and then after combined β-adrenergic and parasympathetic blockade (propranolol 0.6 mg/kg and bilateral vagotomies). Alpha-stimulation was then achieved with phenylephrine given in doses of 0.5, 1.0, and 10.0 μg/kg/ min. A second, high dose of propranolol …